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    • 3. 发明授权
    • Teething toy
    • 牙齿玩具
    • US07695339B2
    • 2010-04-13
    • US11986048
    • 2007-11-21
    • Mary Kathryn FriedmanLarry P. LaPointeCandace M. LaPointeRichard Friedman
    • Mary Kathryn FriedmanLarry P. LaPointeCandace M. LaPointeRichard Friedman
    • A63H33/00
    • A61J17/02A61J7/0053A61J9/06A61J17/006A61J2200/42A61J2200/44A63H33/22
    • A teething toy that is chewable and sensory stimulating uses a hollow cylinder made of a soft clear polymeric material. It is approximately half filled with a colored fluid. Shiny particle specks and different shaped multicolored floating objects are suspended in the fluid. Nipple shaped protrusions extend from end spherical end. A circular handle with oval cross section extends from the side of the cylinder. Directly opposite this handle is a rectangular shaped handle with oval cross section. The sides of both handles have small extension knobs protruding from the narrow sides of the cross sections. Options include longitudinal ribs running along the cylinder surface for easy grasp and manipulation. Additional options include rectangular grips extending, from the sides of the toy. Options include a suction cup and suspended from a flexible plastic cord that tethers the toy to a surface such as a high chair tray.
    • 可咀嚼和感觉刺激的出牙玩具使用由柔软的透明聚合材料制成的中空圆筒。 大约有一半用彩色液体填充。 闪烁的颗粒斑点和不同形状的五彩浮动物体悬浮在流体中。 乳头形突起从端部球形端延伸。 具有椭圆形截面的圆形手柄从气缸的侧面延伸。 与该手柄直接相对的是具有椭圆形横截面的矩形手柄。 两个手柄的侧面具有从横截面的窄边突出的小的延伸旋钮。 选项包括沿着气缸表面延伸的纵向肋条,便于把握和操纵。 附加选项包括从玩具的两侧延伸的矩形把手。 选项包括一个吸盘,并悬挂在柔性塑料绳上,将玩具系在一个表面上,如高脚椅。
    • 8. 发明申请
    • Teething toy
    • 牙齿玩具
    • US20090130944A1
    • 2009-05-21
    • US11986048
    • 2007-11-21
    • Mary Kathryn FriedmanLarry P. LaPointeCandace M. LaPointeRichard Friedman
    • Mary Kathryn FriedmanLarry P. LaPointeCandace M. LaPointeRichard Friedman
    • A61J17/02A63H33/22
    • A61J17/02A61J7/0053A61J9/06A61J17/006A61J2200/42A61J2200/44A63H33/22
    • A teething toy that is chewable and sensory stimulating uses a hollow cylinder made of a soft clear polymeric material. It is approximately half filled with a colored fluid. Shiny particle specks and different shaped multicolored floating objects are suspended in the fluid. Nipple shaped protrusions extend from each spherical end. A circular handle with oval cross section extends from the side of the cylinder. Directly opposite this handle is a rectangular shaped handle with oval cross section. The sides of both handles have small extension knobs protruding from the narrow sides of the cross sections. Options include longitudinal ribs running along the cylinder surface for easy grasp and manipulation. Additional options include rectangular grips extending from the sides of the toy. Other options include a suction cup end suspended from a flexible plastic cord that tethers the toy to a surface such as a high chair tray.
    • 可咀嚼和感觉刺激的出牙玩具使用由柔软的透明聚合材料制成的中空圆筒。 大约有一半用彩色液体填充。 闪烁的颗粒斑点和不同形状的五彩浮动物体悬浮在流体中。 乳头形突起从每个球形端延伸。 具有椭圆形截面的圆形手柄从气缸的侧面延伸。 与该手柄直接相对的是具有椭圆形横截面的矩形手柄。 两个手柄的侧面具有从横截面的窄边突出的小的延伸旋钮。 选项包括沿着气缸表面延伸的纵向肋条,便于把握和操纵。 附加选项包括从玩具的两侧延伸的矩形把手。 其他选项包括从柔性塑料绳悬吊的吸盘端,将玩具系在诸如高脚椅等表面上。
    • 9. 发明申请
    • Rapid tuberculosis detection method
    • 快速结核病检测方法
    • US20070243557A1
    • 2007-10-18
    • US11545748
    • 2006-10-10
    • Richard FriedmanLinoj Samuel
    • Richard FriedmanLinoj Samuel
    • G01N33/569
    • G01N33/5695
    • Methods for diagnosing Mycobacterium tuberculosis infection in a human that include providing blood serum, contacting the serum with an Eis antigen fixed on a substrate, thereby forming complexes of Eis antigen with a human antibody that binds to the Eis antigen, contacting the antibody/Eis complexes with a labeled anti-human secondary antibody, and measuring a titer of the human antibody bound to the Eis antigen. In addition, statistically significant positive or negative diagnosis of infection with Mycobacterium tuberculosis is provided by comparing patient serum antibody titer with a second titer from a negative control blood sample.
    • 用于诊断人类结核分枝杆菌感染的方法,包括提供血清,使血清与固定在底物上的Eis抗原接触,从而形成Eis抗原与与Eis抗原结合的人抗体的复合物,接触抗体/ Eis复合物 与标记的抗人二抗,并测量与Eis抗原结合的人抗体滴度。 此外,通过将阴性对照血液样品的患者血清抗体滴度与第二滴度进行比较,提供了结核分枝杆菌感染的统计学显着的阳性或阴性诊断。