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1. 发明申请

US20120122732A1 Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules 有权
公开(公告)号：US20120122732A1
公开(公告)日：2012-05-17
申请号：US11804583
申请日：2007-05-17
申请人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
发明人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
IPC分类号： C40B40/00 , C40B40/10 , C40B40/14 , C40B40/06 , C40B40/02 , B82Y25/00 , B82Y35/00
CPC分类号： H01F10/3272 , B01J2219/00378 , B01J2219/00497 , B01J2219/00563 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00655 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00734 , B01L3/5027 , B82Y5/00 , B82Y15/00 , B82Y25/00 , B82Y30/00 , C12Q1/6834 , C40B40/06 , C40B40/10 , C40B40/14 , C40B60/14 , C40B70/00 , G01N33/54326 , G01N33/5434 , G01N33/553 , G01N2446/10 , H01F1/0054 , H01F10/3254 , Y10T428/2991 , C12Q2563/143
摘要： Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.

2. 发明授权

US07682838B2 Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules 有权
标题翻译：磁性纳米颗粒，磁性检测器阵列及其用于检测生物分子的方法
公开(公告)号：US07682838B2
公开(公告)日：2010-03-23
申请号：US11938187
申请日：2007-11-09
申请人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
发明人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
IPC分类号： G01N33/543 , G01N1/36
CPC分类号： H01F10/3272 , B01J2219/00378 , B01J2219/00497 , B01J2219/00563 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00655 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00734 , B01L3/5027 , B82Y5/00 , B82Y15/00 , B82Y25/00 , B82Y30/00 , C12Q1/6834 , C40B40/06 , C40B40/10 , C40B40/14 , C40B60/14 , C40B70/00 , G01N33/54326 , G01N33/5434 , G01N33/553 , G01N2446/10 , H01F1/0054 , H01F10/3254 , Y10T428/2991 , C12Q2563/143
摘要： Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.
摘要翻译：公开了磁性纳米颗粒及其用于检测生物分子的方法。磁性纳米颗粒可以连接到核酸分子，然后通过与检测器（例如自旋阀检测器或磁性隧道结检测器）连接的互补序列捕获。可以以高特异性和灵敏度实现结合的磁性纳米颗粒的检测。

3. 发明申请

US20070296477A1 Method and delay circuit with accurately controlled duty cycle 有权
标题翻译：方法和延迟电路具有精确控制的占空比
公开(公告)号：US20070296477A1
公开(公告)日：2007-12-27
申请号：US11473637
申请日：2006-06-23
申请人： Robert L. White
发明人： Robert L. White
IPC分类号： H03K3/017
CPC分类号： H03K5/1565 , H03K5/133 , H03L7/0812
摘要： A delay locked loop includes a storage element coupled to a data bus and produces a data synchronization signal. A phase detector receives a data clock signal and the data synchronization signal and produces a delay control signal. A first delay circuit produces a signal which is delayed relative to the data clock signal according to the delay control signal. A second delay circuit receiving the delayed signal produces a control signal coupled to a control input of the storage element by delaying the delayed signal an amount which causes the control signal to have a predetermined duty cycle.
摘要翻译：延迟锁定环包括耦合到数据总线的存储元件并产生数据同步信号。相位检测器接收数据时钟信号和数据同步信号并产生延迟控制信号。第一延迟电路根据延迟控制信号产生相对于数据时钟信号延迟的信号。接收延迟信号的第二延迟电路通过将延迟信号延迟使控制信号具有预定占空比的量而产生耦合到存储元件的控制输入的控制信号。

4. 发明授权

US5311445A Deconvoluted band representation for infrared spectrum compression 失效
标题翻译：用于红外光谱压缩的解卷积频带表示法
公开(公告)号：US5311445A
公开(公告)日：1994-05-10
申请号：US124522
申请日：1993-09-20
申请人： Robert L. White
发明人： Robert L. White
IPC分类号： G01J3/28 , G01J3/453 , G06F17/00 , G06F15/31 , G06F15/42
CPC分类号： G01J3/28 , G01J2003/2859 , G01J2003/2866 , G01J2003/4538
摘要： Disclosed is a method for infrared spectrum compression wherein a plurality of referenced spectrums each corresponding to one of a plurality of known substances is digitized to obtain a plurality of reference digitized spectrums. The intensity, location and width of each peak for each reference digitized spectrum then is identified and this information is stored. The stored information relating to each of the referenced digitized spectrums is used to compare with an unknown digitized spectrum of an unknown substance to identify the unknown substance.
摘要翻译：公开了一种用于红外光谱压缩的方法，其中将多个已知物质中的一个对应的多个参考光谱数字化以获得多个参考数字化光谱。然后识别每个参考数字化频谱的每个峰值的强度，位置和宽度，并存储该信息。与每个参考数字化频谱相关的存储信息用于与未知物质的未知数字化频谱进行比较以识别未知物质。

5. 发明授权

US5203274A Amphibious vehicle 失效
标题翻译：大型车
公开(公告)号：US5203274A
公开(公告)日：1993-04-20
申请号：US510971
申请日：1990-04-19
申请人： Douglas S. Hart , Larry D. Beller , Robert L. White
发明人： Douglas S. Hart , Larry D. Beller , Robert L. White
IPC分类号： B60F3/00
CPC分类号： B60F3/0023
摘要： A buoyant boat hull of an amphibious vehicle has concave, quarter cylinder recesses along the sides down from the waterline, such recesses receiving the upper inboard quadrants of helical augers. The recesses confine water between the screw threads and project it directly to the rear for more efficient forward thrust. The engine and pumps for the hydraulic motors are mounted on a slide to be moved forward and aft as desired to shift the center of gravity and aid in transition between land and water travel.
摘要翻译：水陆两用车辆的漂浮船体沿着水线沿着侧面具有凹入的四分之一圆柱凹槽，这种凹槽接收螺旋钻的上内侧象限。这些凹槽将水分限制在螺纹之间并将其直接投射到后面以获得更有效的向前推力。用于液压马达的发动机和泵安装在滑块上，以根据需要向前和向后移动，以移动重心并帮助陆地和水道之间的过渡。

6. 发明授权

US4888196A Process for tempering flavored confectionery compositions containing reduced calorie fats and resulting tempered products 失效
标题翻译：用于回火含有低热量脂肪和所产生的回火产品的调味糖果组合物的方法
公开(公告)号：US4888196A
公开(公告)日：1989-12-19
申请号：US329619
申请日：1989-03-28
申请人： Albert M. Ehrman , Paul Seiden , Rose M. Weitzel , Robert L. White
发明人： Albert M. Ehrman , Paul Seiden , Rose M. Weitzel , Robert L. White
IPC分类号： A23G1/00 , A23G1/18 , A23G1/36 , A23G3/00 , A23G3/02 , A23G3/40
CPC分类号： A23G1/36 , A23G1/18 , A23G3/0226 , A23G3/40
摘要： A process for tempering flavored confectionery compositions, in particular chocolate-flavored confectionery compositions, containing certain reduced calorie fats is disclosed. These compositions are rapidly cooled to a temperature of about 57.degree. F. (13.9.degree. C.) or less and then held in this cooler temperature range for typically at least about 16 hours. The cooled composition is then raised to a temperature in the range from above about 57.degree. to about 72.degree. F. (about 13.9.degree. to about 22.2.degree. C.) in a manner such that bloom formation (surface discoloration) does not occur. The resulting tempered product has a firmness and mouthmelt comparable to cocoa butter-based chocolate products.
摘要翻译：公开了一种回收含有某些降低热量的脂肪的调味糖食组合物，特别是巧克力风味糖食组合物的方法。将这些组合物快速冷却至约57°F（13.9℃）或更低的温度，然后保持在该较冷的温度范围内通常至少约16小时。然后将冷却的组合物以不会发生开花形成（表面变色）的方式升高至约57℃至约72℃（约13.9℃至约22.2℃）范围内的温度。所产生的回火产品具有与可可脂基巧克力产品相当的坚固性和口感。

7. 发明授权

US4645679A Process for making a corn chip with potato chip texture 失效
标题翻译：制作玉米片与薯片纹理的方法
公开(公告)号：US4645679A
公开(公告)日：1987-02-24
申请号：US685276
申请日：1984-12-24
申请人： William E. Lee, III , James M. Bangel , Robert L. White , David J. Bruno, Jr.
发明人： William E. Lee, III , James M. Bangel , Robert L. White , David J. Bruno, Jr.
IPC分类号： A23G3/50 , A23L1/164 , A23L1/10 , A23L1/01
CPC分类号： A23L7/13 , Y10S426/808
摘要： A process for making a corn chip with potato chip texture is described. The chip has increased mouthmelt, crispness, and lightness like potato chips and it is less hard and gritty than standard corn chips. It also has a distinctive corn flavor. In a preferred process, corn is cooked in water at 140.degree. F. (60.degree. C.) to 212.degree. F. (100.degree. C.) for 30 minutes to 4 hours. The corn hulls are removed, and the corn is comminuted. A starch material is cooked in water until it is adequately hydrated, and then comminuted. The comminuted corn and starch material are mixed together to form a dough having a ratio of corn to starch material of 95:5 to 80:20. The dough is extruded, formed into a sheet, cut into segments, and deep-fried to form the finished chip.
摘要翻译：描述了制造具有薯片纹理的玉米芯片的方法。该芯片的口感，脆性和轻便如薯片增加，并且比标准玉米片更难硬。它也具有独特的玉米味。在优选的方法中，将玉米在140°F（60℃）至212°F（100℃）的水中煮熟30分钟至4小时。玉米壳被去除，玉米被粉碎。将淀粉材料在水中煮熟直到其充分水合，然后粉碎。将粉碎的玉米和淀粉材料混合在一起形成具有95:5至80:20的玉米与淀粉材料的比例的面团。将面团挤出，形成片材，切成片段，并油炸以形成成品芯片。

8. 发明授权

US07906345B2 Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules 有权
标题翻译：磁性纳米颗粒，磁性检测器阵列及其用于检测生物分子的方法
公开(公告)号：US07906345B2
公开(公告)日：2011-03-15
申请号：US10829505
申请日：2004-04-22
申请人： Shan X Wang , Robert L White , Chris D Webb , Guanxiong Li
发明人： Shan X Wang , Robert L White , Chris D Webb , Guanxiong Li
IPC分类号： G01N33/553 , G01N33/53
CPC分类号： H01F10/3272 , B01J2219/00378 , B01J2219/00497 , B01J2219/00563 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00655 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00734 , B01L3/5027 , B82Y5/00 , B82Y15/00 , B82Y25/00 , B82Y30/00 , C12Q1/6834 , C40B40/06 , C40B40/10 , C40B40/14 , C40B60/14 , C40B70/00 , G01N33/54326 , G01N33/5434 , G01N33/553 , G01N2446/10 , H01F1/0054 , H01F10/3254 , Y10T428/2991 , C12Q2563/143
摘要： Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.
摘要翻译：公开了磁性纳米颗粒及其用于检测生物分子的方法。磁性纳米颗粒可以连接到核酸分子，然后通过与检测器（例如自旋阀检测器或磁性隧道结检测器）连接的互补序列捕获。可以以高特异性和灵敏度实现结合的磁性纳米颗粒的检测。

9. 发明授权

US07615382B2 Magnetic sifter 有权
标题翻译：磁选机
公开(公告)号：US07615382B2
公开(公告)日：2009-11-10
申请号：US11595818
申请日：2006-11-09
申请人： Shan X. Wang , Nader Pourmand , Robert L. White
发明人： Shan X. Wang , Nader Pourmand , Robert L. White
IPC分类号： G01N33/553 , B03C1/30
CPC分类号： B03C1/0335 , B03C2201/18 , B03C2201/22
摘要： The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The magnetic sifter includes at least one substrate. Each substrate contains a plurality of slits, each of which extends through the substrate. The sifter also includes a plurality of magnets attached to the bottom surface of the substrate. These magnets are located proximal to the openings of the slits. An electromagnetic source controls the magnitude and direction of magnetic field gradient generated by the magnets. Either one device may be used, or multiple devices may be used in series. In addition, the magnetic sifter may be used in connection with a detection chamber.
摘要翻译：本发明提供一种规模小的磁选筛机，使得能够沿垂直于基底的方向进行三维流动，允许相对较高的捕获率和较高的流速，并且提供了一种相对容易的释放捕获的生物分子的方法。磁选机包括至少一个衬底。每个基板包含多个狭缝，每个狭缝延伸穿过基板。筛子还包括附着到基底的底表面的多个磁体。这些磁体位于缝隙的开口附近。电磁源控制由磁体产生的磁场梯度的大小和方向。可以使用一个设备，或者可以串联使用多个设备。此外，磁选机可以与检测室结合使用。

10. 发明授权

US06885007B2 Radiation detection apparatus 失效
标题翻译：辐射检测装置
公开(公告)号：US06885007B2
公开(公告)日：2005-04-26
申请号：US10210764
申请日：2002-08-01
申请人： David M. Donaghue , Robert L. White , Leonard W. Zimmermann
发明人： David M. Donaghue , Robert L. White , Leonard W. Zimmermann
IPC分类号： A61N5/10 , G01J1/42 , G01T1/00 , G01T1/16 , G01T1/17 , G01T1/185 , G01T1/24
CPC分类号： G01T1/244 , A61N5/1048
摘要： A radiation detection system has a linear array of radiation detectors, which are preferably ionization chambers. The detectors are connected, preferably permanently, to a multi-channel signal processor through a flexible multi-conductor shielded cable. The multi-channel signal processor is connected to a controller, such as a personal computer, through a multi-conductor cable and a communication interface device. Multiple detector arrays and multi-channel electrometers may be connected to a single personal computer and used simultaneously.
摘要翻译：放射线检测系统具有辐射检测器的线性阵列，其优选为电离室。检测器优选地通过柔性多导体屏蔽电缆连接到多通道信号处理器。多声道信号处理器通过多芯电缆和通信接口装置连接到诸如个人计算机的控制器。多个检测器阵列和多通道静电计可以连接到单个个人计算机并同时使用。

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