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1. 发明授权

US06959836B2 Dispenser 有权
标题翻译：分配器
公开(公告)号：US06959836B2
公开(公告)日：2005-11-01
申请号：US10204574
申请日：2001-02-19
申请人： Michael Collasius , Konstantin Lutze , Pius Fink , Marco Di Berardino
发明人： Michael Collasius , Konstantin Lutze , Pius Fink , Marco Di Berardino
IPC分类号： G01N1/38 , G01N35/10 , G01F11/00
CPC分类号： G01N1/38 , G01N35/1002 , G01N35/1074
摘要： The invention relates to a dispensing device and a method for dispensing liquids, preferably reagents, in an essentially automated and finely dosed manner. The dispensing device comprises a first duct that is connected to a storage element for storing the liquid to be dispensed. In addition, a conveying element for conveying the liquid through the fist duct is provided, whereby the liquid has to be dispensed. Liquid is transported from the storage element and is conveyed into the first duct by the conveying element. Moreover, the dispensing device is provided with a closing device that is arranged downstream in the conveying direction of the liquid in relation to the conveying element and serves for quickly closing and quickly opening the first duct. The aim of the invention is to regulate the pressure of the liquid in the region between the conveying element and the closing device. A device for regulating the pressure of the liquid in this region is provided. Liquids can be very exactly and repeatedly dispensed in short time intervals by means of the inventive device and the inventive method. In another embodiment of the invention, a dispensing element is provided for evenly dividing the liquid stream into partial streams.
摘要翻译：本发明涉及一种分配装置和一种以基本上自动化和精细计量的方式分配液体，优选试剂的方法。分配装置包括连接到用于存储要分配的液体的存储元件的第一管道。此外，提供了用于通过第一导管输送液体的输送元件，由此液体必须被分配。液体从存储元件输送并通过输送元件输送到第一管道中。此外，分配装置设置有关于装置，该封闭装置相对于输送元件布置在液体的输送方向的下游，并用于快速关闭并快速打开第一管道。本发明的目的是调节输送元件和关闭装置之间的区域中的液体的压力。提供了用于调节该区域中的液体的压力的装置。通过本发明的装置和本发明的方法，液体可以以短时间间隔非常精确和重复地分配。在本发明的另一个实施例中，提供了用于将液体流均匀地分成部分流的分配元件。

2. 发明申请

US20150158177A1 PIPETTING ROBOT 审中-公开
标题翻译：运动机器人
公开(公告)号：US20150158177A1
公开(公告)日：2015-06-11
申请号：US14407176
申请日：2012-06-11
申请人： Pius Fink
发明人： Pius Fink
IPC分类号： B25J9/16 , G01N35/10 , G01N35/00
CPC分类号： B25J9/1671 , B25J9/1679 , G01N35/0099 , G01N35/10
摘要： The invention concerns a method of manufacturing a pipetting robot adjusted for desired operation, a method of controlling said pipetting robot, a method of fault diagnostics for said pipetting robot, a method of programming said pipetting robot, a pipetting robot system, and a computer program product. This is achieved with the provision on a computer of a simulation of the pipetting robot with control inputs simulated, and responding identically to the pipetting robot on receipt of identical control signals.
摘要翻译：本发明涉及一种制造针对所需操作进行调节的移液机器人的方法，一种控制所述移液机器人的方法，所述移液机器人的故障诊断方法，编程所述移液机器人的方法，移液机器人系统和计算机程序产品。这是通过在计算机上提供模拟控制输入的移液机器人的模拟实现的，并且在接收到相同的控制信号时与移液机器人的响应相同。

3. 发明授权

US09121841B2 Pipetting arrangement and method of controlling a pipetting arrangement or of producing liquid product doses 有权
标题翻译：移液装置和控制移液装置或产生液体产品剂量的方法
公开(公告)号：US09121841B2
公开(公告)日：2015-09-01
申请号：US13697916
申请日：2010-05-14
申请人： Pius Fink
发明人： Pius Fink
IPC分类号： B01L3/02 , G01N35/10
CPC分类号： G01N35/1009 , B01L3/021 , B01L2300/0861 , B01L2400/0475 , B01L2400/0487 , B01L2400/0694 , B01L2400/082 , G01N35/1011 , G01N35/1072 , Y10T137/0318
摘要： The invention relates to a pipetting arrangement comprising at least two sets of pipettes (9a; 9b; 9c; 9d). Each set of pipettes (9a; 9b; 9c; 9d) is operationally connected, via a controllable ON/OFF valve (11a; 11b; 11e; 11d) to a common aspiration port (7). Latter is connectable to a pumping arrangement (3). The valves (11a; 11b; 11e; 11d) are controlled by a timing-control unit (15) conceived to establish, by control of the valves (11a; 11b; 11e; 11d), the operational connections of the at least two sets of pipettes (9a; 9b; 9c; 9d) to the aspiration port (7) in a time-multiplexed manner.
摘要翻译：本发明涉及包括至少两组移液管（9a; 9b; 9c; 9d）的移液装置。每组移液器（9a; 9b; 9c; 9d）通过可控的开/关阀（11a; 11b; 11e; 11d）可操作地连接到公共抽吸口（7）。后部可连接到泵送装置（3）。阀门（11a; 11b; 11e; 11d）由定时控制单元（15）控制，该定时控制单元（15）通过控制阀（11a; 11b; 11e; 11d）建立至少两组的操作连接的移液管（9a; 9b; 9c; 9d）以时间复用的方式连接到抽吸口（7）。

4. 发明授权

US07250767B2 Method for introducing a liquid sample into an NMR spectrometer 有权
标题翻译：将液体样品引入NMR光谱仪的方法
公开(公告)号：US07250767B2
公开(公告)日：2007-07-31
申请号：US11144779
申请日：2005-06-06
申请人： Martin Hofmann , Pius Fink
发明人： Martin Hofmann , Pius Fink
IPC分类号： G01V3/00
CPC分类号： G01R33/307
摘要： A method for introducing a liquid sample into an NMR spectrometer to measure an NMR spectrum of the liquid sample, wherein the liquid sample is injected into a supply line and wherein further liquids are supplied into the supply line following the liquid sample, which are separated from each other and from the liquid sample by gas bubbles is characterized in that the liquid sample is supplied via an injection inlet to a valve configuration whose output side can be connected to the supply line and the further liquids and gas are supplied to the valve configuration via supply lines, wherein a desired sequence of sample segments, gas bubbles and further liquid segments is generated through temporally matched switching of the valve configuration in the supply line and is supplied to the NMR spectrometer. The inventive method realizes supply of a liquid sample into an NMR spectrometer with rapid sample transfer while thereby preventing mixing and dilution of the individual segments.
摘要翻译：一种用于将液体样品引入NMR光谱仪中以测量液体样品的NMR光谱的方法，其中将液体样品注入供应管线，并且其中进一步的液体被供应到液体样品之后的供应管线中，其特征在于，液体样品通过注射入口供给到阀构造，其输出侧可以连接到供应管线，并且进一步的液体和气体经由供应管线，其中通过供应管线中的阀配置的时间匹配切换产生样品段，气泡和另外的液体段的期望序列，并将其提供给NMR光谱仪。本发明的方法实现了将液体样品供应到具有快速样品转移的NMR光谱仪中，从而防止各个片段的混合和稀释。

5. 发明申请

US20130056079A1 PIPETTING ARRANGEMENT AND METHOD OF CONTROLLING A PIPETTING ARRANGEMENT OR OF PRODUCING LIQUID PRODUCT DOSES 有权
标题翻译：管道布置方式和控制排水装置或生产液体产品的方法
公开(公告)号：US20130056079A1
公开(公告)日：2013-03-07
申请号：US13697916
申请日：2010-05-14
申请人： Pius Fink
发明人： Pius Fink
IPC分类号： B01L3/02
CPC分类号： G01N35/1009 , B01L3/021 , B01L2300/0861 , B01L2400/0475 , B01L2400/0487 , B01L2400/0694 , B01L2400/082 , G01N35/1011 , G01N35/1072 , Y10T137/0318
摘要： The invention relates to a pipetting arrangement comprising at least two sets of pipettes (9a; 9b; 9c; 9d). Each set of pipettes (9a; 9b; 9c; 9d) is operationally connected, via a controllable ON/OFF valve (11a; 11b; 11e; 11d) to a common aspiration port (7). Latter is connectable to a pumping arrangement (3). The valves (11a; 11b; 11e; 11d) are controlled by a timing-control unit (15) conceived to establish, by control of the valves (11a; 11b; 11e; 11d), the operational connections of the at least two sets of pipettes (9a; 9b; 9c; 9d) to the aspiration port (7) in a time-multiplexed manner.
摘要翻译：本发明涉及包括至少两组移液管（9a; 9b; 9c; 9d）的移液装置。每组移液器（9a; 9b; 9c; 9d）通过可控的开/关阀（11a; 11b; 11e; 11d）可操作地连接到公共抽吸口（7）。后部可连接到泵送装置（3）。阀门（11a; 11b; 11e; 11d）由定时控制单元（15）控制，该定时控制单元（15）通过控制阀（11a; 11b; 11e; 11d）建立至少两组的操作连接的移液管（9a; 9b; 9c; 9d）以时间复用的方式连接到抽吸口（7）。

6. 发明申请

US20050280416A1 Method for introducing a liquid sample into an NMR spectrometer 有权
标题翻译：将液体样品引入NMR光谱仪的方法
公开(公告)号：US20050280416A1
公开(公告)日：2005-12-22
申请号：US11144779
申请日：2005-06-06
申请人： Martin Hofmann , Pius Fink
发明人： Martin Hofmann , Pius Fink
IPC分类号： G01R33/30 , G01V3/00
CPC分类号： G01R33/307
摘要： A method for introducing a liquid sample into an NMR spectrometer to measure an NMR spectrum of the liquid sample, wherein the liquid sample is injected into a supply line and wherein further liquids are supplied into the supply line following the liquid sample, which are separated from each other and from the liquid sample by gas bubbles is characterized in that the liquid sample is supplied via an injection inlet to a valve configuration whose output side can be connected to the supply line and the further liquids and gas are supplied to the valve configuration via supply lines, wherein a desired sequence of sample segments, gas bubbles and further liquid segments is generated through temporally matched switching of the valve configuration in the supply line and is supplied to the NMR spectrometer. The inventive method realizes supply of a liquid sample into an NMR spectrometer with rapid sample transfer while thereby preventing mixing and dilution of the individual segments.
摘要翻译：一种用于将液体样品引入NMR光谱仪中以测量液体样品的NMR光谱的方法，其中将液体样品注入供应管线，并且其中进一步的液体被供应到液体样品之后的供应管线中，其特征在于，液体样品通过注射入口供给到阀构造，其输出侧可以连接到供应管线，并且进一步的液体和气体经由供应管线，其中通过供应管线中的阀配置的时间匹配切换产生样品段，气泡和另外的液体段的期望序列，并将其提供给NMR光谱仪。本发明的方法实现了将液体样品供应到具有快速样品转移的NMR光谱仪中，从而防止各个片段的混合和稀释。

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