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1. 发明申请

US20120165693A1 Detection of Respiratory System Lesions 有权
标题翻译：呼吸系统病变检测
公开(公告)号：US20120165693A1
公开(公告)日：2012-06-28
申请号：US12874456
申请日：2010-09-02
申请人： Deryk John Peter Williams , Jonh Jam Peter Williams , Mark Sinclair Varney , Michael Garrett
发明人： Deryk John Peter Williams , Jonh Jam Peter Williams , Mark Sinclair Varney , Michael Garrett
IPC分类号： A61B5/08
CPC分类号： A61B5/082 , A61B2562/029
摘要： Humidity profiles of exhaled air of individuals obtained using a sensor to detect water vapour content or temperature versus time of exhalation may exhibit an irregularity indicative of a space-occupying respiratory system lesion. Detection of such irregularities provides an inexpensive and rapid means of pre-screening individuals for lung cancer diagnosis, and is applicable even to individuals with other respiratory disorders such as asthma and COPD.
摘要翻译：使用传感器检测水蒸汽含量或温度与呼气时间获得的个人呼出空气的湿度曲线可能表现出指示空间占据呼吸系统病变的不规则性。这种不规则检测提供了一种便宜且快速的预筛选个体用于肺癌诊断的方法，并且甚至适用于具有其它呼吸系统疾病如哮喘和COPD的个体。

2. 发明授权

US09261434B2 Tire uniformity testing system having a testing station for changing rim sets 有权
标题翻译：轮胎均匀性测试系统具有用于更换轮辋组的测试台
公开(公告)号：US09261434B2
公开(公告)日：2016-02-16
申请号：US13885850
申请日：2011-11-22
申请人： James Wollbrinck , Richard R. Matuszny , Barry Cargould , Peter Williams
发明人： James Wollbrinck , Richard R. Matuszny , Barry Cargould , Peter Williams
IPC分类号： G01M17/02 , B60C23/00 , B60C23/02 , B60C25/00
CPC分类号： G01M17/02 , B60C25/002 , G01M17/021 , Y10T29/49815 , Y10T29/49826
摘要： An apparatus for changing rim sets at a testing station of a tire uniformity testing system that includes a storage unit for storing a plurality of rim set assemblies. A transfer arm is reciprocally movable and includes a gripper mechanism for gripping a rim set assembly and moving it from a storage position to a position at which rims forming part of the rim set assembly are aligned with opposed spindles at the testing station. The rim set assembly includes a bracket having structure engageable by the transfer arm and at least one of the rims forming part of the assembly includes a locking member rotatable between a first position and a second position. The bracket includes a structure for immobilizing the rim to inhibit relative rotation between the rim and the bracket and further includes a lever mechanism for moving the locking member from its first position to its second position in order to engage retaining members forming part of the bracket. The lever mechanism moves the locking member from its second position to its first position when the rim is aligned with an associated spindle in order to engage other retaining members forming part of the spindle. The rim is released from the bracket as the locking member moves to engage the other retaining members. After release, the bracket moves to a remote position spaced from the testing station. To remove the rim sets, the steps for attaching rims to the spindles are reversed in order to release the rims from the spindles while simultaneously engaging the bracket. The resulting rim set assembly is moved to a remote position defined by a storage unit that stores a plurality of rim set assemblies. The disclosed locking member and associated rim can be used to facilitate the manual installation of a test rim to a spindle.
摘要翻译：一种用于在轮胎均匀性测试系统的测试站处改变轮辋组件的装置，其包括用于存储多个轮辋组件的存储单元。传送臂是可往复运动的，并且包括夹持机构，用于夹持轮圈组件并将其从存放位置移动到形成轮圈组件的一部分的轮缘与测试台处的相对的主轴对准的位置。轮辋组件包括具有可由传送臂接合的结构的支架，并且构成组件的一部分的至少一个轮辋包括可在第一位置和第二位置之间旋转的锁定构件。支架包括用于固定轮缘以阻止轮缘和支架之间的相对旋转的结构，并且还包括杠杆机构，用于将锁定构件从其第一位置移动到其第二位置，以便接合构成支架的一部分的保持构件。当边缘与相关联的主轴对准时，杠杆机构将锁定构件从其第二位置移动到其第一位置，以便接合形成主轴的一部分的其它保持构件。当锁定构件移动以与其它保持构件接合时，边缘从支架释放。释放后，支架移动到与测试站隔开的远程位置。为了拆下轮辋组，将轮辋连接到主轴上的步骤是相反的，以便在同时接合支架的同时将轮辋从主轴上松开。所得到的轮圈组件移动到由存储多个轮圈组件的存储单元限定的远程位置。所公开的锁定构件和相关联的边缘可以用于便于将试验轮辋手动安装到主轴。

3. 发明授权

US09221034B2 Process for preparing catalysts 有权
标题翻译：制备催化剂的方法
公开(公告)号：US09221034B2
公开(公告)日：2015-12-29
申请号：US12446108
申请日：2007-10-18
申请人： Graeme Douglas Campbell , Gordon James Kelly , Fiona Mary Campbell , Brian Peter Williams
发明人： Graeme Douglas Campbell , Gordon James Kelly , Fiona Mary Campbell , Brian Peter Williams
IPC分类号： B01J27/232 , B01J23/80 , B01F3/12 , B01F11/00 , B01J8/40 , B01J19/00 , B01J19/24 , B01J23/00 , B01J37/03 , B01J35/00 , B01J35/02 , B01J37/00 , B01J37/14 , B01J37/16
CPC分类号： B01J23/80 , B01F3/12 , B01F11/0071 , B01J8/40 , B01J19/006 , B01J19/243 , B01J23/002 , B01J35/0053 , B01J35/023 , B01J37/0009 , B01J37/031 , B01J37/08 , B01J37/14 , B01J37/16 , B01J2219/00777 , B01J2523/00 , B01J2523/12 , B01J2523/17 , B01J2523/22 , B01J2523/27 , B01J2523/31 , B01J2523/842
摘要： A process for manufacturing a catalyst composition comprises the steps of (i) precipitating one or more metal compounds from solution using an alkaline precipitant, preferably comprising an alkaline carbonate, optionally in the presence of a thermostabilizing material, ii) ageing the precipitated composition, and (iii) recovering and drying the aged composition, wherein the ageing step is performed using a pulse-flow reactor.
摘要翻译：制备催化剂组合物的方法包括以下步骤：（i）任选地在热稳定材料存在下，使用碱性沉淀剂，优选包含碱性碳酸盐，从溶液中沉淀一种或多种金属化合物，ii）使沉淀的组合物老化，以及（iii）回收和干燥老化组合物，其中老化步骤使用脉冲流反应器进行。

4. 发明授权

US08537042B2 Multi-bit digital to analogue converter and a delta-sigma analogue to digital converter 有权
标题翻译：多位数模转换器和一个delta-sigma模数转换器
公开(公告)号：US08537042B2
公开(公告)日：2013-09-17
申请号：US13359741
申请日：2012-01-27
申请人： Hashem Zare-Hoseini , Peter Williams
发明人： Hashem Zare-Hoseini , Peter Williams
IPC分类号： H03M1/66 , H03M3/02
CPC分类号： H03M1/0665 , H03M1/74 , H03M3/464
摘要： The present invention relates to a multi-bit digital to analogue converter (DAC) and to a delta-sigma analogue to digital converter employing such a DAC. The DAC has a multi-bit input, a plurality of elements for processing an input signal received at the input and a selector for selecting, based on the input signal, one or more of the DAC elements to process the signal. The DAC has control means for controlling the selector such that if the input to the DAC is below a predetermined level for a predetermined period of time the selector is operative to select only a single one of the DAC elements to process the input signal. Also disclosed is a delta-sigma analogue to digital converter (ADC) employing such a DAC.
摘要翻译：本发明涉及一种多位数模转换器（DAC）以及采用这种DAC的Δ-Σ模数转换器。 DAC具有多位输入，用于处理在输入端接收的输入信号的多个元件和用于根据输入信号选择一个或多个DAC元件来处理该信号的选择器。 DAC具有用于控制选择器的控制装置，使得如果DAC的输入在预定时间段内低于预定电平，则选择器仅可操作以仅选择DAC单元中的一个来处理输入信号。还公开了采用这种DAC的Δ-Σ模数转换器（ADC）。

5. 发明授权

US08486713B2 Mass spectrometric immunoassay 失效
标题翻译：质谱免疫测定
公开(公告)号：US08486713B2
公开(公告)日：2013-07-16
申请号：US13421633
申请日：2012-03-15
申请人： Randall W. Nelson , Peter Williams , Jennifer Reeve Krone
发明人： Randall W. Nelson , Peter Williams , Jennifer Reeve Krone
IPC分类号： G01N24/00
CPC分类号： G01N24/00 , C12Q1/6816 , C12Q1/6872 , G01N33/5302 , G01N33/54373 , G01N33/6851 , Y10T436/24
摘要： Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass spectrum obtained for an antibody/antigen of known concentration.
摘要翻译：用于利用亲和捕获来检测和/或定量抗体和抗原分析物以分离分析物和内部参考物质（用于定量），随后对分离的分析物/内部参考物质进行质谱分析的快速质谱免疫测定方法。通过对获得的已知浓度的抗体/抗原的质谱进行标准化和校准获得的质谱来获得定量。

6. 发明申请

US20130173028A1 Systems and Methods for Extending Physical Sensor Range Using Virtual Sensors 有权
标题翻译：使用虚拟传感器扩展物理传感器范围的系统和方法
公开(公告)号：US20130173028A1
公开(公告)日：2013-07-04
申请号：US13338646
申请日：2011-12-28
申请人： Timothy Joe Felty , James Robert Mason , Stuart Paul Smith , Anthony James Grichnik , Gavin Peter Williams
发明人： Timothy Joe Felty , James Robert Mason , Stuart Paul Smith , Anthony James Grichnik , Gavin Peter Williams
IPC分类号： G05B9/02
CPC分类号： G05B13/02
摘要： A control system is disclosed. The control system may have a physical sensor that may output a physical output value, and a virtual sensor network that may output a virtual output value. The control system may also have an electronic control module that may be configured to receive the physical output value from the physical sensor and receive the virtual output value from the virtual sensor. The electronic control module may be further configured to determine a trust level of the physical sensor based on the physical output value, and determine that the trust level of the physical sensor is below a first threshold trust value. The electronic control module may control a machine based on the virtual output value responsive to determining that the trust level of the physical sensor is below the first threshold trust value.
摘要翻译：公开了一种控制系统。控制系统可以具有可以输出物理输出值的物理传感器以及可以输出虚拟输出值的虚拟传感器网络。控制系统还可以具有电子控制模块，其可被配置为从物理传感器接收物理输出值并从虚拟传感器接收虚拟输出值。电子控制模块还可以被配置为基于物理输出值来确定物理传感器的信任级别，并且确定物理传感器的信任级别低于第一阈值信任值。响应于确定物理传感器的信任级别低于第一阈值信任值，电子控制模块可基于虚拟输出值来控制机器。

7. 发明授权

US08458451B2 Database outsourcing with access privacy 有权
标题翻译：数据库外包与访问隐私
公开(公告)号：US08458451B2
公开(公告)日：2013-06-04
申请号：US12321326
申请日：2009-01-20
申请人： Dennis Shasha , Peter Williams , Radu Sion
发明人： Dennis Shasha , Peter Williams , Radu Sion
IPC分类号： H04L29/06
CPC分类号： H04L63/0435 , G06F11/1004 , G06F21/54 , G06F21/602 , G06F21/606 , G06F21/6263 , G06F2221/2101 , G06F2221/2151
摘要： This invention introduces a new paradigm for outsourcing the transaction processing backend of a multi-client database application to an untrusted service provider. Specifically, the invention enables untrusted service providers to support transaction serialization, backup and recovery for clients, with full data confidentiality and correctness. Moreover, providers learn nothing about transactions (except their size and timing), thus achieving read and write access pattern privacy.
摘要翻译：本发明引入了将多客户端数据库应用的事务处理后端外包给不可信服务提供商的新范例。具体来说，本发明使得不信任的服务提供商能够以完整的数据机密性和正确性支持客户端的事务序列化，备份和恢复。此外，提供商对事务（尺寸和时间除外）也没有学习，从而实现读写访问模式隐私。

8. 发明授权

US08403861B2 Detection of respiratory system lesions 有权
标题翻译：检测呼吸系统病变
公开(公告)号：US08403861B2
公开(公告)日：2013-03-26
申请号：US12874456
申请日：2010-09-02
申请人： Deryk John Peter Williams , Mark Sinclair Varney , Michael Garrett
发明人： Deryk John Peter Williams , Mark Sinclair Varney , Michael Garrett
IPC分类号： A61B5/08
CPC分类号： A61B5/082 , A61B2562/029
摘要： Humidity profiles of exhaled air of individuals obtained using a sensor to detect water vapor content or temperature versus time of exhalation may exhibit an irregularity indicative of a space-occupying respiratory system lesion. Detection of such irregularities provides an inexpensive and rapid means of pre-screening individuals for lung cancer diagnosis, and is applicable even to individuals with other respiratory disorders such as asthma and COPD.
摘要翻译：使用传感器检测水蒸汽含量或温度与呼气时间获得的个人呼出空气的湿度曲线可能表现出指示空间占据呼吸系统病变的不规则性。这种不规则检测提供了一种便宜且快速的预筛选个体用于肺癌诊断的方法，并且甚至适用于具有其它呼吸系统疾病如哮喘和COPD的个体。

9. 发明申请

US20120202681A1 CARBON OXIDES CONVERSION PROCESS 有权
标题翻译：碳氧化物转化过程
公开(公告)号：US20120202681A1
公开(公告)日：2012-08-09
申请号：US13378589
申请日：2010-05-24
申请人： Colin William Park , Brian Peter Williams , Graeme Douglas Campbell , David Allan Buckworth
发明人： Colin William Park , Brian Peter Williams , Graeme Douglas Campbell , David Allan Buckworth
IPC分类号： B01J21/04 , C01B3/16 , C07C29/154 , C07C41/01 , B01J21/06 , B01J21/10
CPC分类号： B01J21/04 , B01J23/80 , B01J35/0026 , B01J35/0053 , B01J35/023 , B01J37/0045 , B01J37/12 , B01J37/18 , C01B3/16 , C07C29/154 , Y02P20/52 , C07C31/04
摘要： A carbon oxides conversion process includes reacting a carbon oxide containing process gas containing hydrogen and/or steam and containing at least one of hydrogen and carbon monoxide in the presence of a catalyst including shaped units formed from a reduced and passivated catalyst powder, the powder including copper in the range 10-80% by weight, zinc oxide in the range 20-90% by weight, alumina in the range 5-60% by weight and optionally one or more oxidic promoter compounds selected from compounds of Mg, Cr, Mn, V, Ti, Zr, Ta, Mo, W, Si and rare earths in the range 0.01-10% by weight, wherein said shaped units have a reduced to as-made mean horizontal crush strength ratio of ≧0.5:1 and a copper surface area above 60 m2/g Cu.
摘要翻译：碳氧化物转化方法包括在包含由还原和钝化的催化剂粉末形成的成形单元的催化剂存在下，使含有氢和/或蒸汽的含氧化物的工艺气体与氢和一氧化碳中的至少一种反应，所述粉末包括铜的范围为10-80重量％，氧化锌在20-90重量％范围内，氧化铝在5-60重量％范围内，以及任选的一种或多种氧化促进剂化合物，其选自Mg，Cr，Mn ，V，Ti，Zr，Ta，Mo，W，Si和稀土在0.01-10重量％的范围内，其中所述成形单元的平均横向抗压强度比为0.5:1; 铜表面积高于60 m2 / g Cu。

10. 发明授权

US08216514B2 Method of determining the nucleotide sequence of Oligonucleotides and DNA molecules 有权
标题翻译：确定寡核苷酸和DNA分子的核苷酸序列的方法
公开(公告)号：US08216514B2
公开(公告)日：2012-07-10
申请号：US13156117
申请日：2011-06-08
申请人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
发明人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
IPC分类号： G01N15/06 , C12Q1/68 , C12P19/34 , C07H19/04
CPC分类号： C12Q1/6869 , C12Q1/6816 , C12Q1/6825 , C12Q2533/101 , C12Q2563/103 , C12Q2563/107 , C12Q2563/116 , C12Q2565/301 , C12Q2565/629 , G01N33/573 , G01N33/6863
摘要： The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.
摘要翻译：本发明涉及一种用于分析核酸序列的新方法，该方法基于DNA聚合酶催化的四个核苷酸碱基中的每一个（在微流体系统中单独提供和连续供给）中并入到包含模板系统的反应池中包含未知序列的DNA片段和寡核苷酸引物。将核苷酸碱基掺入模板系统可以通过多种方法中的任何一种检测，包括但不限于荧光和化学发光检测。或者，可以使用通过使用热电堆，热敏电阻和折射率测量将核苷酸并入扩展模板系统产生的热的微量热法测定来检测延伸反应。

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