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1. 发明授权

US07037260B2 Method and apparatus for determining attention deficit hyperactivity disorder (ADHD) medication dosage and for monitoring the effects of ADHD medication on people who have ADHD using complementary tests 失效
标题翻译：用于确定注意力缺陷多动障碍（ADHD）药物用量的方法和装置，并用于使用补充测试监测ADHD药物对ADHD患者的影响
公开(公告)号：US07037260B2
公开(公告)日：2006-05-02
申请号：US10832824
申请日：2004-04-27
申请人： Richard S. Keirsbilck , Peter A. Parks , David L. Patton , Richard N. Blazey , Paige Miller
发明人： Richard S. Keirsbilck , Peter A. Parks , David L. Patton , Richard N. Blazey , Paige Miller
IPC分类号： A61B5/00
CPC分类号： A61B5/01 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00
摘要： A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD. The method comprises sampling the peripheral skin temperature of left and right like extremities of an individual during a predetermined time interval when the individual is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data, processing the sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures whose magnitudes are indicative of the level of ADHD manifestation. The effectiveness of the medication is calculated by comparison to predetermined threshold values.
摘要翻译：用于确定在具有ADHD的个体中治疗注意力缺陷多动障碍（ADHD）的药物的适当剂量的方法。该方法包括当个体处于感觉剥夺状态时在预定时间间隔期间对个体的左右四肢的周边皮肤温度进行采样，以提供相应的左和右采样的外周皮肤温度数据，处理采样的外周皮肤温度数据 ; 处理采样的外围皮肤温度数据，包括滤波，微分和转换到频域，以导出其幅度表示ADHD表现水平的光谱特征。通过与预定阈值进行比较来计算药物的有效性。

2. 发明授权

US06652470B2 Using image modification and temperature biofeedback to diagnose and treat ADHD 有权
标题翻译：使用图像修改和温度生物反馈来诊断和治疗ADHD
公开(公告)号：US06652470B2
公开(公告)日：2003-11-25
申请号：US09747216
申请日：2000-12-21
申请人： David L. Patton , Richard N. Blazey , Peter A. Parks
发明人： David L. Patton , Richard N. Blazey , Peter A. Parks
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B3/113 , A61B5/0002 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00 , G16H15/00
摘要： A method of reducing the symptoms of an individual having Attention Deficit Hyperactivity Disorder (ADHD) comprising: displaying an image, having a level of obscuration, to an individual with the symptoms of ADHD; sampling the peripheral skin temperature of the individual to provide sampled peripheral skin temperature data and reducing the level of obscuration of the image as a function of the sampled peripheral skin temperature data in order to minimize the symptoms of ADHD.
摘要翻译：一种降低患有注意缺陷多动障碍（ADHD）的个体的症状的方法，包括：对具有ADHD症状的个体显示具有遮蔽程度的图像; 对个体的周边皮肤温度进行采样，以提供采样的周边皮肤温度数据，并根据采样的周边皮肤温度数据降低图像的遮蔽程度，以便最大限度地减少ADHD的症状。

3. 发明授权

US06527730B2 Reducing noise in a technique for diagnosing attention deficit hyperactivity disorder 失效
公开(公告)号：US06527730B2
公开(公告)日：2003-03-04
申请号：US09746052
申请日：2000-12-21
申请人： Richard N. Blazey , David L. Patton , Peter A. Parks
发明人： Richard N. Blazey , David L. Patton , Peter A. Parks
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B5/168
摘要： A method of determining whether an individual has Attention Deficit Hyperactivity Disorder (ADHD) comprising: sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state to provide a sampled peripheral skin temperature signal containing noise: modulating said sampled peripheral skin temperature signal containing noise with a known reference signal to produce a modulated signal; inputting said modulated signal and said known reference signal to a lock-in amplifier to produce a sampled peripheral skin temperature signal free of said noise; and analyzing the sampled peripheral skin temperature signal for a pre-selected parameter to determine whether said predetermined parameter has a value indicative of ADHD.

4. 发明授权

US06746409B2 Technique for diagnosing attention deficit hyperactivity disorder using complimentary tests 失效
标题翻译：使用免费测试诊断注意缺陷多动障碍的技术
公开(公告)号：US06746409B2
公开(公告)日：2004-06-08
申请号：US10076261
申请日：2002-02-14
申请人： Richard S. Keirsbilck , Richard N. Blazey , Peter A. Parks , David L. Patton , Paige Miller
发明人： Richard S. Keirsbilck , Richard N. Blazey , Peter A. Parks , David L. Patton , Paige Miller
IPC分类号： A61B500
CPC分类号： A61B5/168 , A61B5/7257 , A61B5/726
摘要： A method of determining threshold values, subsequently used to determine whether an individual has Attention Deficit Hyperactivity Disorder (ADHD) comprising: providing a group of subjects, a segment of which is known to have ADHD and a segment is known to not have ADHD; and testing each subject in the group by: (a) sampling the peripheral skin temperature of left and right like extremities during a predetermined time interval when the subject is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data; (b) processing the sampled peripheral skin temperature data, including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures having magnitude values; and (c) final processing of spectral signatures for all of the subjects of the group to determine threshold values which are complimentarily effective for determining whether or not an individual has ADHD when tested by the testing method.
摘要翻译：一种确定阈值的方法，随后用于确定个体是否具有注意缺陷多动障碍（ADHD），其包括：提供一组受试者，其一部分已知具有ADHD并且已知细节不具有ADHD; 并且通过以下步骤对所述组中的每个受试者进行测试：（a）当所述对象处于感觉剥夺状态时，在预定时间间隔期间对左右四肢的外周皮肤温度进行采样，以提供相应的左和右采样的外周皮肤温度数据; （b）处理采样的外围皮肤温度数据，包括滤波，微分和转换到频域以导出具有幅度值的光谱特征; 和（c）对组的所有受试者的光谱特征的最终处理，以确定当通过测试方法测试时，个体具有ADHD是否有ADHD的阈值。

5. 发明授权

US06306077B1 Management of physiological and psychological state of an individual using images overall system 失效
标题翻译：使用图像整体系统管理个人的生理和心理状态
公开(公告)号：US06306077B1
公开(公告)日：2001-10-23
申请号：US09430580
申请日：1999-10-29
申请人： Girish V. Prabhu , Cecelia M. Horwitz , Paige Miller , Richard N. Blazey , Elena A. Fedorovskaya , Swatee N. Surve , David L. Patton , Laurie Schaefer , John R. Fredlund , Jose V. Mir , Peter A. Parks
发明人： Girish V. Prabhu , Cecelia M. Horwitz , Paige Miller , Richard N. Blazey , Elena A. Fedorovskaya , Swatee N. Surve , David L. Patton , Laurie Schaefer , John R. Fredlund , Jose V. Mir , Peter A. Parks
IPC分类号： A61M2100
CPC分类号： A61B5/486 , A61B5/16 , A61B5/7257 , A61B5/7264 , G06F19/00
摘要： A method of managing a physiological or psychological state of an individual using images comprising: determining an individual's direction or preference for a state management session; based on the determination, deciding whether a current set of images selected through a personal image profile session, will achieve the desired management effect; if the current set are deemed satisfactory, presenting the set of images to the individual to achieve management of the individual's state.
摘要翻译：使用图像管理个体的生理或心理状态的方法，包括：确定个人对于状态管理会话的方向或偏好; 基于确定，决定通过个人图像配置文件会话选择的当前图像集是否将实现期望的管理效果; 如果当前集合被认为是令人满意的，则将该组图像呈现给个人以实现个人状态的管理。

6. 发明授权

US06726624B2 METHOD AND APPARATUS FOR DETERMINING ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD) MEDICATION DOSAGE AND FOR MONITORING THE EFFECTS OF ADHD MEDICATION ON PEOPLE WHO HAVE ADHD USING COMPLEMENTARY TESTS 失效
标题翻译：用于确定缺陷性高血压疾病（ADHD）药物剂量和用于监测ADHD药物对具有ADHD的患者使用补充测试的方法和装置
公开(公告)号：US06726624B2
公开(公告)日：2004-04-27
申请号：US10092284
申请日：2002-03-06
申请人： Richard S. Keirsbilck , Peter A. Parks , David L. Patton , Richard N. Blazey , Paige Miller
发明人： Richard S. Keirsbilck , Peter A. Parks , David L. Patton , Richard N. Blazey , Paige Miller
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00
摘要： A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD. The method comprises sampling the peripheral skin temperature of left and right like extremities of an individual during a predetermined time interval when the individual is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures whose magnitudes are indicative of the level of ADHD manifestation. The effectiveness of the medication is calculated by comparison to predetermined threshold values.
摘要翻译：用于确定在具有ADHD的个体中治疗注意力缺陷多动障碍（ADHD）的药物的适当剂量的方法。该方法包括当个体处于感觉剥夺状态时在预定时间间隔期间对个体的左右四肢的周边皮肤温度进行采样，以提供相应的左和右采样的外周皮肤温度数据; 处理采样的外围皮肤温度数据; 处理采样的外围皮肤温度数据，包括滤波，微分和转换到频域，以导出其幅度表示ADHD表现水平的光谱特征。通过与预定阈值进行比较来计算药物的有效性。

7. 发明授权

US06652458B2 ADHD detection by eye saccades 有权
标题翻译： ADHD检测通过眼睛扫视
公开(公告)号：US06652458B2
公开(公告)日：2003-11-25
申请号：US09866183
申请日：2001-05-25
申请人： Richard N. Blazey , David L. Patton , Peter A. Parks
发明人： Richard N. Blazey , David L. Patton , Peter A. Parks
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B3/113 , A61B5/0002 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00 , G16H15/00
摘要： A method of determining whether an individual has Attention Deficit Hyperactivity Disorder comprising: sampling the eye movement of a human subject during a predetermined time interval when the subject is in an inactive state to provide sampled eye movement data; and analyzing the sampled eye movement data for a pre-selected parameter, to determine whether said pre-selected parameter has a value indicative of ADHD.
摘要翻译：一种确定个体是否具有注意力缺陷多动障碍的方法，包括：当所述对象处于非活动状态时，在预定时间间隔期间对人类受试者的眼睛运动进行采样，以提供采样的眼睛运动数据; 以及分析采样的眼睛运动数据以获得预选参数，以确定所述预选参数是否具有指示ADHD的值。

8. 发明授权

US06565518B2 Technique for diagnosing attention deficit hyperactivity disorder 失效
标题翻译：诊断注意缺陷多动障碍的技术
公开(公告)号：US06565518B2
公开(公告)日：2003-05-20
申请号：US09865902
申请日：2001-05-25
申请人： Richard N. Blazey , Peter A. Parks , David L. Patton , Paige Miller
发明人： Richard N. Blazey , Peter A. Parks , David L. Patton , Paige Miller
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B5/168 , A61B5/7257 , A61B5/726
摘要： A method for determining a threshold value of a parameter used to determine whether an individual has Attention Deficit Hyperactivity Disorder (ADHD). The method includes: providing a group of individuals a segment of which is known to have ADHD and a segment of which is known to be normal and not have ADHD; testing each individual in the group by sampling the peripheral skin temperature of the individual during a pre-determined time interval when the individual is in an inactive state to provide sampled peripheral skin temperature data, and analyzing the sampled peripheral skin data to produce a parameter value for that individual. The method further includes: processing the individual parameter values for all of the members of the group to determine a threshold parameter value which is acceptable for determining whether or not an individual has ADHD when tested by the testing procedure.
摘要翻译：用于确定用于确定个体是否具有注意缺陷多动障碍（ADHD）的参数的阈值的方法。该方法包括：提供一组个体，其一部分已知具有ADHD，其一部分已知是正常的且没有ADHD; 通过在个体处于非活动状态的预定时间间隔期间对个体的周边皮肤温度进行采样来提供组中的每个个体以提供采样的周边皮肤温度数据，并分析采样的外围皮肤数据以产生参数值对于那个人所述方法还包括：处理组的所有成员的各个参数值，以确定当通过测试程序测试时可以判断个体是否具有ADHD的阈值参数值。

9. 发明授权

US06482165B1 Homekit for determining attention deficit hyperactivity disorder 失效
标题翻译：用于确定注意缺陷多动障碍的家庭套件
公开(公告)号：US06482165B1
公开(公告)日：2002-11-19
申请号：US09692682
申请日：2000-10-19
申请人： David L. Patton , Richard N. Blazey , Peter A. Parks
发明人： David L. Patton , Richard N. Blazey , Peter A. Parks
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B3/113 , A61B5/00 , A61B5/0002 , A61B5/0482 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00 , G16H15/00
摘要： A kit and method for determining whether an individual has Attention Deficit Hyperactivity Disorder, comprising a device for sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state, and an analyzer for analyzing the sampled peripheral skin temperature data for a pre-selected parameter, to determine whether the pre-selected parameter has a value indicative of ADHD.
摘要翻译：一种用于确定个体是否具有注意力缺陷多动障碍的试剂盒和方法，包括用于在受试者处于非活动状态的预定时间间隔期间对人类受试者的外周皮肤温度进行取样的装置和用于分析采样周边用于预选参数的皮肤温度数据，以确定预选参数是否具有指示ADHD的值。

10. 发明授权

US06394963B1 Technique for diagnosing attention deficit disorder 有权
标题翻译：诊断注意缺陷障碍的技术
公开(公告)号：US06394963B1
公开(公告)日：2002-05-28
申请号：US09597610
申请日：2000-06-20
申请人： Richard N. Blazey , Peter A. Parks , David L. Patton
发明人： Richard N. Blazey , Peter A. Parks , David L. Patton
IPC分类号： A61B500
CPC分类号： A61B5/01 , A61B3/113 , A61B5/0002 , A61B5/168 , A61B5/7257 , A61B5/726 , G06F19/00 , G16H15/00
摘要： A method of determining whether an individual has Attention Deficit Disorder (ADD) comprising: sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state to provide sampled peripheral skin temperature data; and analyzing the sampled peripheral skin temperature data for a pre-selected parameter, to determine whether said pre-selected parameter has a value indicative of ADD.
摘要翻译：一种确定个体是否具有注意缺陷障碍（ADD）的方法，包括：当所述受试者处于非活动状态时，在预定时间间隔期间对人类受试者的外周皮肤温度进行取样以提供取样的周边皮肤温度数据; 并且对采样的周边皮肤温度数据进行分析以预选参数，以确定所述预选参数是否具有指示ADD的值。

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