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1. 发明公开

US20240207223A1 VITAMIN C PREPARATION 审中-公开
公开(公告)号：US20240207223A1
公开(公告)日：2024-06-27
申请号：US18108509
申请日：2023-02-10
申请人： PEDRO P. PEREZ
发明人： PEDRO P. PEREZ
IPC分类号： A61K31/375 , A61K31/352 , A61K47/10 , A61K47/12
CPC分类号： A61K31/375 , A61K31/352 , A61K47/10 , A61K47/12
摘要： The present invention relates to vitamin C preparations which enhance absorption of vitamin C into cells and prolong the retention of vitamin C within the blood plasma and tissue of mammals, such as humans. The vitamin C preparations of the present invention include lipophilic molecules which improve the absorption of vitamin C resulting in higher plasma and cellular levels.

2. 发明公开

US20240299300A1 LIPOSOME VITAMIN C PREPARATION 审中-公开
公开(公告)号：US20240299300A1
公开(公告)日：2024-09-12
申请号：US18595072
申请日：2024-03-04
申请人： Pedro P Perez
发明人： Pedro P Perez
IPC分类号： A61K9/127 , A61K31/375 , A61P39/06
CPC分类号： A61K9/127 , A61K31/375 , A61P39/06
摘要： The present invention relates to liposome vitamin C preparations which enhance absorption of vitamin C into cells and prolong the retention of liposome vitamin C within the blood plasma and tissue of mammals, such as humans. The liposome vitamin C preparations of the present invention include amphipathic and amphiphilic molecules which improve the absorption of liposome vitamin C resulting in higher plasma and cellular levels.

3. 发明公开

US20240226121A1 PHYTOCANNABINOID FORMULATIONS AND METHODS FOR EXTRACTION 审中-公开
公开(公告)号：US20240226121A1
公开(公告)日：2024-07-11
申请号：US18433084
申请日：2024-02-05
申请人： Pedro P. Perez
发明人： Pedro P. Perez
IPC分类号： A61K31/00 , A61K9/00 , A61K9/06 , A61K9/20 , A61K9/48 , A61K47/12 , A61K47/22 , A61K47/24 , A61K47/36 , A61K47/44 , A61K47/46
CPC分类号： A61K31/658 , A61K9/0095 , A61K9/06 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2068 , A61K9/4858 , A61K9/4875 , A61K47/12 , A61K47/22 , A61K47/24 , A61K47/36 , A61K47/44 , A61K47/46
摘要： A phytocannabinoid formulation comprises an amount of at least about 90 percent by weight of one or more phytocannabinoid. The phytocannabinoid formulation further comprises an amount of at least about 0.1 percent by weight of a plurality of lipophilic molecules including at least one saturated straight chain C14-C20 fatty acid and at least one unsaturated ω-6 C18-C22 fatty acid. The phytocannabinoid formulation also includes an amount of at least about 0.1 percent by weight of at least one bioflavonoid.

4. 发明授权

US07141611B2 High molecular weight primary aliphatic alcohols obtained from natural products and uses thereof 有权
标题翻译：由天然产物获得的高分子量伯脂肪醇及其用途
公开(公告)号：US07141611B2
公开(公告)日：2006-11-28
申请号：US10622249
申请日：2003-07-18
申请人： William R. Gamble , Zhengjie Liu , David T. Bailey , Pedro P. Perez , Dean P. Stull , Steven L. Richheimer , Rebecca L. Nichols , Rod Lenoble
发明人： William R. Gamble , Zhengjie Liu , David T. Bailey , Pedro P. Perez , Dean P. Stull , Steven L. Richheimer , Rebecca L. Nichols , Rod Lenoble
IPC分类号： A61K31/045 , C07C29/76 , C07C29/28 , C07C29/86
CPC分类号： C07C29/76 , C07C29/86 , C07C31/125 , C07C33/025
摘要： This invention provides an isolated mixture of higher molecular weight primary aliphatic alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms and having enhanced purity. This invention also provides a process for obtaining the alcohol mixture by extracting a natural product with organic solvents with or without saponification of the natural product. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering total cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels and therefore is effective in treating hypercholesterolemia. The composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis), and can be used as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.
摘要翻译：本发明提供了具有20,22,24,26,27,28,30,32和34个碳原子的较高分子量伯脂肪醇的分离混合物，并且具有增强的纯度。本发明还提供了一种通过在天然产物皂化或不皂化的情况下用有机溶剂萃取天然产物来获得醇混合物的方法。酒精混合物可用于药物组合物，食品和膳食补充剂中，并有效降低总胆固醇和低密度脂蛋白胆固醇并增加HDL-胆固醇水平，因此有效治疗高胆固醇血症。该组合物可用于降低冠心病的风险，抑制动脉粥样硬化过程（血小板超聚集，缺血和血栓形成），并可用作抗炎和抗血栓形成剂。该组合物还具有神经营养性质，可用于改善男性的性活动。

5. 发明授权

US06225354B1 High molecular weight primary aliphatic alcohols obtained from beeswax and pharmaceutical use thereof 有权
标题翻译：从蜂蜡获得的高分子量伯脂肪醇及其药物用途
公开(公告)号：US06225354B1
公开(公告)日：2001-05-01
申请号：US09337339
申请日：1999-06-21
申请人： Pedro P. Perez
发明人： Pedro P. Perez
IPC分类号： A61K31045
CPC分类号： C07C29/76 , C07C31/02
摘要： The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 24 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from beeswax without saponification ofthe beeswax. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 24, 26, 27, 28, 29, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol in LDL-C levels so that it is effective in treating hypercholesterolemia. Consequently the composition may be used to reduce the risk of coronary heart disease, the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis) and also acts as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.
摘要翻译：本发明涉及天然得到的含有24至34个碳原子的较高分子量伯脂肪醇的混合物。本发明还涉及通过蜂蜡中的有机溶剂提取和纯化而获得醇混合物的方法，而不需要将蜂蜡皂化。从蜂蜡获得的醇混合物具有提高的纯度，并且含有具有24,26,27,28,29,30,32和34个碳原子的醇的混合物。醇混合物可用于药物组合物，食品和膳食补充剂中，并且可有效降低LDL-C水平的胆固醇，从而有效治疗高胆固醇血症。因此，该组合物可用于降低冠心病，动脉粥样硬化过程（血小板超聚集，局部缺血和血栓形成）的风险，并且还用作抗炎和抗血栓形成剂。该组合物还具有神经营养性质，可用于改善男性的性活动。

6. 发明申请

US20210106555A1 PHYTOCANNABINOID FORMULATIONS AND METHODS FOR EXTRACTION 有权
公开(公告)号：US20210106555A1
公开(公告)日：2021-04-15
申请号：US17070047
申请日：2020-10-14
申请人： Pedro P. Perez
发明人： Pedro P. Perez
IPC分类号： A61K31/352 , A61K47/10 , A61K47/12 , A61K31/05 , A61K47/26
摘要： A phytocannabinoid formulation comprises an amount of at least about 90 percent by weight of one or more phytocannabinoid. The phytocannabinoid formulation further comprises an amount of at least about 0.1 percent by weight of a plurality of lipophilic molecules including at least one saturated straight chain C14-C20 fatty acid and at least one unsaturated ω-6 C18-C22 fatty acid. The phytocannabinoid formulation also includes an amount of at least about 0.1 percent by weight of at least one bioflavonoid.

7. 发明申请

US20080207748A1 VITAMIN C PREPARATION 审中-公开
标题翻译：维生素C制剂
公开(公告)号：US20080207748A1
公开(公告)日：2008-08-28
申请号：US12035987
申请日：2008-02-22
申请人： Pedro P. Perez
发明人： Pedro P. Perez
IPC分类号： A61K31/375 , A61P25/00
CPC分类号： A61K31/355 , A61K9/2013 , A61K9/4858 , A61K31/20 , A61K31/202 , A61K31/35 , A61K31/375 , A61K2300/00
摘要： The present invention relates to vitamin C preparations which enhance absorption of vitamin C into cells, and prolong the retention of vitamin C within the blood plasma and tissue of mammals, such as humans. The vitamin C preparations of the present invention include lipophilic molecules which improve the absorption of vitamin C resulting in higher plasma and cellular levels.
摘要翻译：本发明涉及增加维生素C吸收细胞的维生素C制剂，并延长维生素C在哺乳动物如人的血浆和组织中的保留。本发明的维生素C制剂包括改善维生素C吸收的亲脂性分子，导致更高的血浆和细胞水平。

8. 发明授权

US06596776B2 High molecular weight primary aliphatic alcohols obtained from natural products and uses thereof 有权
公开(公告)号：US06596776B2
公开(公告)日：2003-07-22
申请号：US10133986
申请日：2002-04-25
申请人： William R. Gamble , Zhengjie Liu , David T. Bailey , Pedro P. Perez , Dean P. Stull , Steven L. Richheimer , Rebecca L. Nichols , Rod Lenoble
发明人： William R. Gamble , Zhengjie Liu , David T. Bailey , Pedro P. Perez , Dean P. Stull , Steven L. Richheimer , Rebecca L. Nichols , Rod Lenoble
IPC分类号： A61K31045
CPC分类号： C07C29/76 , C07C29/86 , C07C31/125 , C07C33/025
摘要： The present invention relates to a naturally obtained mixture of higher molecular weight primary aliphatic alcohols which contain 20 to 34 carbon atoms. This invention also relates to the process for obtaining the alcohol mixture by extraction and purification with organic solvents from a natural product, such as beeswax with and without saponification of the natural product. The alcohol mixture obtained from beeswax has enhanced purity and contains a mixture of alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels so that it is effective in treating hypercholesterolemia. Consequently the composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis) and also to act as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.

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