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1. 发明授权

US08968270B2 Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment 有权
标题翻译：更换胃肠旁路套管进行治疗调整的方法
公开(公告)号：US08968270B2
公开(公告)日：2015-03-03
申请号：US13373999
申请日：2011-12-05
申请人： Jonathan Kagan , Mitchell Dann , Lee Guterman , Joshua Butters , Paul Swain , T. Wade Fallin , Thomas Baldwin
发明人： Jonathan Kagan , Mitchell Dann , Lee Guterman , Joshua Butters , Paul Swain , T. Wade Fallin , Thomas Baldwin
IPC分类号： A61M31/00 , A61B17/064 , A61B17/00 , A61B17/04 , A61B17/11 , A61B17/12 , A61F2/04 , A61F5/00 , A61B17/29 , A61B17/06
CPC分类号： A61F5/0076 , A61B17/00234 , A61B17/0401 , A61B17/0482 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B17/1114 , A61B17/12 , A61B17/29 , A61B2017/00349 , A61B2017/00827 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/0647 , A61B2017/0649 , A61F2/04 , A61F5/0036 , A61F5/0086 , A61F2002/044
摘要： Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.
摘要翻译：公开了用于可替换地附接在患者消化道内用于治疗肥胖症的腔内胃肠装置（例如人工造口装置，胃肠旁路套管装置或附件袖带）的方法。

2. 发明申请

US20120232459A1 DEVICES AND METHODS FOR ENDOLUMENAL GASTROINTESTINAL BYPASS 审中-公开
标题翻译：内分泌胃肠旁路旁路器的设备及方法
公开(公告)号：US20120232459A1
公开(公告)日：2012-09-13
申请号：US13476884
申请日：2012-05-21
申请人： Mitchell Dann , Joshua Butters , Greg Fluet , Lee Guterman , Jonathan Kagan , Paul Swain , Gerard von Hoffmann , James Wright
发明人： Mitchell Dann , Joshua Butters , Greg Fluet , Lee Guterman , Jonathan Kagan , Paul Swain , Gerard von Hoffmann , James Wright
IPC分类号： A61M5/00
CPC分类号： A61F5/0076 , A61B17/00234 , A61B17/0401 , A61B17/0482 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B17/1114 , A61B17/12 , A61B17/29 , A61B2017/00349 , A61B2017/00827 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/0647 , A61B2017/0649 , A61F2/04 , A61F5/0036 , A61F5/0086 , A61F2002/044
摘要： The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.
摘要翻译：本发明提供了用于在患者的消化道内附着腔内胃肠装置的装置和方法，例如人造气道装置，胃肠旁路套管或其他治疗或诊断装置。在本发明的一个应用中，腹腔内旁路套管可移除地附接在胃食管结合部附近以治疗肥胖症和/或其合并症，例如糖尿病。旁路套管可以至少部分地通过外翻来展开。

3. 发明申请

US20120209164A1 Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment 审中-公开
标题翻译：更换胃肠旁路套管进行治疗调整的方法
公开(公告)号：US20120209164A1
公开(公告)日：2012-08-16
申请号：US13373999
申请日：2011-12-05
申请人： Jonathan Kagan , Mitchell Dann , Lee Guterman , Joshua Butters , Paul Swain , T. Wade Fallin , Thomas Baldwin
发明人： Jonathan Kagan , Mitchell Dann , Lee Guterman , Joshua Butters , Paul Swain , T. Wade Fallin , Thomas Baldwin
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61B17/00234 , A61B17/0401 , A61B17/0482 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B17/1114 , A61B17/12 , A61B17/29 , A61B2017/00349 , A61B2017/00827 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/0647 , A61B2017/0649 , A61F2/04 , A61F5/0036 , A61F5/0086 , A61F2002/044
摘要： Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.
摘要翻译：公开了用于可替换地附接在患者消化道内用于治疗肥胖症的腔内胃肠装置（例如人工造口装置，胃肠旁路套管装置或附件袖带）的方法。

4. 发明申请

US20120029535A1 DEVICES AND METHODS FOR TRANSMURAL ANCHOR DELIVERY VIA A TUBULAR BODY 审中-公开
标题翻译：用于通过管状体输送的输送锚固装置和方法
公开(公告)号：US20120029535A1
公开(公告)日：2012-02-02
申请号：US13196812
申请日：2011-08-02
申请人： Paul Swain
发明人： Paul Swain
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0401 , A61B2017/0404 , A61B2017/0417 , A61B2017/0496 , A61B2017/06052
摘要： Disclosed is a transmural tissue anchor deployment system and method, for attachment to a tissue wall. The method can include the steps of advancing the tubular body through a single, non-plicated tissue wall of the gastrointestinal tract; ejecting the tissue attachment structure out of the tubular body such that the retention surface rests against a serosal surface of the tissue wall; and withdrawing the tubular body proximally across the tissue wall, wherein the tension element spans the single non-plicated tissue wall after withdrawal of the tubular body.
摘要翻译：公开了一种用于附着到组织壁的透壁组织锚展开系统和方法。该方法可以包括以下步骤：使管状体通过胃肠道的单个的，非打孔的组织壁前进; 将组织附着结构从管状体排出，使得保持表面靠在组织壁的浆膜表面上; 以及将所述管状体向近端撤回穿过所述组织壁，其中所述张紧元件在所述管状体撤回之后跨越所述单个非打浆组织壁。

5. 发明授权

US07846138B2 Cuff and sleeve system for gastrointestinal bypass 有权
标题翻译：袖口系统用于胃肠旁路
公开(公告)号：US07846138B2
公开(公告)日：2010-12-07
申请号：US11430274
申请日：2006-05-08
申请人： Mitchell Dann , Jonathan Kagan , Paul Swain , Joshua Butters , Lee Guterman
发明人： Mitchell Dann , Jonathan Kagan , Paul Swain , Joshua Butters , Lee Guterman
IPC分类号： A61M5/00
CPC分类号： A61F5/0076 , A61B17/00234 , A61B17/0401 , A61B17/0482 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B17/1114 , A61B17/12 , A61B17/29 , A61B2017/00349 , A61B2017/00827 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/0647 , A61B2017/0649 , A61F2/04 , A61F5/0036 , A61F5/0086 , A61F2002/044
摘要： The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removeably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.
摘要翻译：本发明提供了用于在患者的消化道内附着腔内胃肠装置的装置和方法，例如人造气道装置，胃肠旁路套管或其他治疗或诊断装置。在本发明的一个应用中，腔内旁路套管可移除地附着在胃食管结合部附近以治疗肥胖症和/或其并发症，例如糖尿病。旁路套管可以至少部分地通过外翻来展开。

6. 发明申请

US20080221619A1 Surgical suture anchors and deployment device 有权
标题翻译：外科缝合锚和部署装置
公开(公告)号：US20080221619A1
公开(公告)日：2008-09-11
申请号：US11715710
申请日：2007-03-08
申请人： James T. Spivey , David Stefanchik , Christopher Paul Swain
发明人： James T. Spivey , David Stefanchik , Christopher Paul Swain
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0445 , A61B2017/0446 , A61B2017/0488 , Y10T24/3916
摘要： A suture anchor is provided which includes a hollow member having an outer surface defining an enclosure therein, the member having a longitudinal axis and a slot through a portion of the outer surface in a direction transverse to the longitudinal axis, the slot providing an opening into the enclosure. The suture anchor further includes a one-way valve positioned within the enclosure at the slot to allow entry of a suture through the slot into the enclosure and to prevent the exit of the suture from the enclosure. A device is provided for deploying the suture anchor. The deployment device includes an elongate hollow member having a suture anchor release zone positioned at the distal end thereof, a launch bar having at least a portion thereof positioned in the release zone, wherein the launch bar is movable within the release zone between a resting position and a launching position and is operatively connected to an actuation member positioned proximally to the elongate member. The hollow elongate member defines a housing for receiving a plurality of suture anchors in tandem along the longitudinal axis of the hollow member, wherein each of the suture anchors is configured for release from the release zone when such suture anchor is positioned within the release zone upon movement of the launch bar from the resting position to the launching position.
摘要翻译：提供了缝合锚，其包括具有限定其中的外壳的外表面的中空构件，所述构件具有纵向轴线和穿过外表面的横向于纵向轴线的一部分的狭槽，所述狭槽提供开口外壳。缝合锚还包括位于外壳内的单向阀，该单向阀位于狭槽处，以允许缝线通过狭槽进入外壳并防止缝合线从外壳排出。提供了用于展开缝线锚的装置。展开装置包括细长的中空构件，其具有位于其远端处的缝合线锚释放区，发射杆至少有一部分位于释放区中，其中发射杆可在释放区域内在静止位置和发射位置，并且可操作地连接到位于细长构件的近侧的致动构件。中空细长构件限定了用于沿着中空构件的纵向轴线串联地接收多个缝合锚的壳体，其中每个缝合线锚构件被构造成当这种缝合锚固件位于释放区域内时从释放区域释放，发射杆从静止位置移动到发射位置。

7. 发明申请

US20080108868A1 Device, System and Method of In-Vivo Electro-Stimulation 审中-公开
标题翻译：体内电刺激的装置，系统和方法
公开(公告)号：US20080108868A1
公开(公告)日：2008-05-08
申请号：US11792254
申请日：2005-12-04
申请人： Christopher Paul Swain , Charles Alexander Mosse , Timothy Noel Mills
发明人： Christopher Paul Swain , Charles Alexander Mosse , Timothy Noel Mills
IPC分类号： A61B1/00
CPC分类号： A61N1/36007 , A61B1/00016 , A61B1/00156 , A61B1/04 , A61B1/041 , A61B5/07 , A61N1/37205
摘要： An autonomous in-vivo device (140) includes: an in-vivo electro-stimulation unit (190, 192) to electro-stimulate at least a portion of a body lumen; and an imager (146) to acquire in-vivo images.
摘要翻译：自主体内装置（140）包括：体内电刺激单元（190,192），用于电刺激体腔的至少一部分; 以及用于获取体内图像的成像器（146）。

8. 发明申请

US20070010864A1 Gastrointestinal implant system 审中-公开
标题翻译：胃肠道植入系统
公开(公告)号：US20070010864A1
公开(公告)日：2007-01-11
申请号：US11429934
申请日：2006-05-08
申请人： Mitchell Dann , Jonathan Kagan , Paul Swain , Joshua Butters , Lee Guterman
发明人： Mitchell Dann , Jonathan Kagan , Paul Swain , Joshua Butters , Lee Guterman
IPC分类号： A61F2/06
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0482 , A61B17/0487 , A61B17/0643 , A61B17/0644 , A61B17/1114 , A61B17/12 , A61B17/29 , A61B2017/00349 , A61B2017/00827 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06052 , A61B2017/0647 , A61B2017/0649 , A61F2/04 , A61F5/0076 , A61F5/0086 , A61F2002/044 , A61F2220/0016
摘要： The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removeably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.
摘要翻译：本发明提供了用于在患者的消化道内附着腔内胃肠装置的装置和方法，例如人造气道装置，胃肠旁路套管或其他治疗或诊断装置。在本发明的一个应用中，腔内旁路套管可移除地附着在胃食管结合部附近以治疗肥胖症和/或其并发症，例如糖尿病。旁路套管可以至少部分地通过外翻来展开。

9. 发明申请

US20050165389A1 Microwave hollow organ probe 审中-公开
标题翻译：微波中空器官探针
公开(公告)号：US20050165389A1
公开(公告)日：2005-07-28
申请号：US10519676
申请日：2003-07-08
申请人： Paul Swain , Malcolm Birch , Jonathan Reeves
发明人： Paul Swain , Malcolm Birch , Jonathan Reeves
IPC分类号： A61B17/00 , A61B18/18 , A61B18/04
CPC分类号： A61B18/1815 , A61B18/18 , A61B2018/0022
摘要： An apparatus for heat ablation of the internal wall of a hollow organ such as the oesophagus comprises a catheter having at least one internal lumen, a balloon located at the distal end of the catheter and attached to a lumen, a supply of a liquid for filling the balloon via the lumen, a tuned microwave antenna located in the region of the balloon for radiating microwave energy at a predetermined frequency to heat the balloon to a temperature suitable for heat ablation of the hollow organ wall tissue, a waveguide for supplying microwave energy to the microwave antenna, and a temperature probe to measure the temperature of the balloon. The balloon is filled from the proximal end of the catheter with a liquid having a dielectric constant of from 41 to 63 and a conductivity of from 1.0 Sm−1 to 1.5 Sm−1.
摘要翻译：用于诸如食道的中空器官的内壁的热消融的装置包括具有至少一个内腔的导管，位于导管的远端并附接到内腔的气囊，用于填充的液体的供应通过管腔的球囊，位于球囊区域中的调谐微波天线，用于以预定频率辐射微波能量以将球囊加热到适于中空器官壁组织的热消融的温度;用于将微波能量提供给微波天线和温度探头，以测量气球的温度。从导管的近端填充气球，其介电常数为41〜63，导电率为1.0Sm -1〜1.5Sm -1。 >。

10. 发明授权

US06358259B1 Device for use in tying knots 有权
标题翻译：用于打结的装置
公开(公告)号：US06358259B1
公开(公告)日：2002-03-19
申请号：US09428782
申请日：1999-10-28
申请人： Paul Swain , Feng Gong , Geoffrey John Brown , Timothy Noel Mills
发明人： Paul Swain , Feng Gong , Geoffrey John Brown , Timothy Noel Mills
IPC分类号： A61B1704
CPC分类号： A61B1/00089 , A61B17/0469 , A61B17/0482 , A61B17/12013 , A61B2017/00296 , A61B2017/0474 , A61B2017/0475
摘要： A thread guide device is provided which is adapted to be removably or fixedly mounted on the distal end of an endoscope, or which is an integral part thereof. Alternatively, the device may comprise a head joined to the distal end of an elongate example in the form of longitudinally extending passages, which are laterally spaced from one another. The device permits a knot formed by threads which have passed through the thread guides to be viewed by the endoscope.
摘要翻译：提供了一种线引导装置，其适于可拆卸地或固定地安装在内窥镜的远端上，或者其是其一部分。或者，装置可以包括以纵向延伸的通道的形式连接到细长实例的远端的头部，其彼此横向间隔开。该装置允许由穿过导线器的螺纹形成的结被内窥镜观察。

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