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1. 发明申请

US20220387454A1 NUTRITIONAL COMPOSITION FOR VISUAL FUNCTION 有权
公开(公告)号：US20220387454A1
公开(公告)日：2022-12-08
申请号：US17762727
申请日：2020-11-10
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Muralidhara PADIGARU , Abhijeet MORDE , Prakash BHANUSE
IPC分类号： A61K31/593 , A61K31/047 , A61K31/12 , A61K47/44 , A61K47/24 , A61K47/14 , A61P27/04
摘要： A nutritional composition for prevention, improvement and maintenance of visual function. The nutritional composition comprising the nutrients and at least one pharmaceutically and/or nutraceutically accepted excipient. The nutritional composition wherein the nutrients are selected from one or more of lutein, curcumin and vitamin D3 for prevention, improvement and maintenance of dry eye. The process of preparation of the nutritional composition comprising lutein, curcumin and vitamin D3 use for visual function more specifically dry eye. The present invention is further encompassing to the nutritional composition comprising lutein, curcumin, vitamin D3 in selective percentage which is formulated in different forms like as, powders, granules, pellets, beadlets, caplets, tablets, capsules, soft gel capsules, solution, emulsions, suspensions, oil suspensions, dispersions and the like.

2. 发明授权

US11382879B2 Methods for improving physical performance and capsicum compositions used therein 有权
公开(公告)号：US11382879B2
公开(公告)日：2022-07-12
申请号：US16329479
申请日：2017-08-29
申请人： OmniActive Health Technologies Limited
发明人： Jayant Deshpande , Khadija Ghanam , Vijaya Juturu
IPC分类号： A61K31/165 , A61K36/81
摘要： Methods of improving physical performance and endurance include administering a capsicum composition to a subject. More particularly the methods include administration of an effective amount of a capsicum composition including capsaicinoids alone and/or in combination with other nutrients for improvement in performance of physical activities. The methods described include administration of a capsicum composition to a subject undergoing physical activity to deliver daily dose of capsaicinoids in an effective amount. The methods include administering a capsicum composition to a subject in an effective amount to reduce blood lipids and oxidative stress. Methods for enhancing physical endurance and exhaustion time include administering an effective amount of a capsicum composition to a physically active subject, wherein body antioxidants are increased and muscle lactates are decreased, resulting in recovery from muscle fatigue arising due to such indoor and/or outdoor physical activities.

3. 发明授权

US10583095B2 Method for stress management and overall health status improvement and compositions used therein 有权
公开(公告)号：US10583095B2
公开(公告)日：2020-03-10
申请号：US15058821
申请日：2016-03-02
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Jayant Deshpande , James M. Stringham , Vijaya Juturu
IPC分类号： A61K31/047 , A61K31/07 , A61P25/00 , A61P27/00 , G01N33/74 , G01N33/487 , G01N30/00 , G01N21/59 , G01N30/88
摘要： Carotenoid compositions are described for management, treatment, and/or prevention of stress by reducing cortisol levels and/or improving distribution and/or density of macular pigment and thus improving overall health status. More particularly, a subject in need thereof for the method has disturbed macular pigment optical density or increased levels of cortisol as markers of psychological and physiological stress. Methods are also described of administering macular carotenoid compositions in daily doses of at least or about 0.005 mg/kg body weight of lutein, and at least or about 0.001 mg/kg body weight of meso-zeaxanthin and zeaxanthin isomer along with at least one food grade excipient and evaluating overall health status. The composition may be derived from plant extract containing xanthophylls and/or xanthophylls esters. The composition also reduces cortisol levels in the blood and relieves physiological stress, thus improving overall health status of a subject in need thereof.

4. 发明申请

US20180370891A1 CURCUMIN COMPOSITIONS FOR IMPROVEMENT IN CARDIOVASCULAR FLOW 审中-公开
公开(公告)号：US20180370891A1
公开(公告)日：2018-12-27
申请号：US15774875
申请日：2016-11-09
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Jayant DESHPANDE , Vijaya JUTURU
IPC分类号： C07C49/84 , A61P9/08
摘要： Curcumin compositions are described for administration to healthy subjects, in need thereof, for improving cardiovascular flow. Curcumin compositions described herein can be administered to a subject in an effective dose of 250 mg to 1000 mg, corresponding to about 50 mg to 200 mg curcuminoids, for improvement of endothelial function and reducing risk of cardiovascular diseases. Compositions herein include curcumin either alone or curcumin along with at least one excipient to enhance absorption. Compositions herein improve endothelial function in healthy subjects having FMD value of 5-7% or higher and who are not diagnosed with cardiovascular disease. Compositions herein also improve cardiovascular endothelial function by reducing vascular resistance and enhancing nitric oxide generation in vascular endothelium. Curcumin compositions herein are safe for consumption, possesses enhanced absorption and can be employed for improvement of endothelial function and cardiovascular flow, when administered in an effective dose to a healthy subject, in need thereof.

5. 发明申请

US20160051490A1 NEUROPROTECTIVE EFFECT OF CAROTENOIDS IN BRAIN 有权
标题翻译：卡介质在脑中的神经保护作用
公开(公告)号：US20160051490A1
公开(公告)日：2016-02-25
申请号：US14780595
申请日：2014-03-28
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Jayant DESHPANDE , J. SHANKARANARAYANAN
IPC分类号： A61K31/047 , A61K31/198
CPC分类号： A61K31/047 , A61K31/07 , A61K31/198 , A61P25/16 , A61K2300/00
摘要： The present invention provides use of composition containing molecular dispersions of carotenoids for the prevention of neurodegenerative disorders which are safe for human consumption and are particularly useful as dietary supplements for nutrition and health promoting benefits. The present invention particularly relates to the use of highly water soluble composition with enhanced bioavailability containing at least 80% by weight of total xanthophylls, out of which the trans-lutein content is 80-95% w/w; (R,R)-zeaxanthin is 14-20% w/w; (R,S)-zeaxanthin is 0.01-1% w/w and traces of other carotenoids derived from the plant extracts/oleoresin containing xanthophylls/xanthophylls esters. The present invention also provides use of the said composition in treatment of neurodegenerative disorders when co-administered along with reduced dose of Levodopa and Carbidopa.
摘要翻译：本发明提供了含有类胡萝卜素分子分散体的组合物用于预防对人类消费具有安全性的神经变性疾病的用途，并且特别可用作营养和健康促进益处的膳食补充剂。本发明特别涉及具有增加的生物利用度的高度水溶性组合物的用途，所述组合物含有至少80％（重量）的总叶绿素，其中异黄酮含量为80-95％w / w; （R，R） - 次黄豆素为14-20％w / w; （R，S） - 茶黄素的含量为0.01-1％w / w，其他类胡萝卜素衍生自植物提取物/含有油茶叶的叶黄素/叶黄素酯。本发明还提供了当与同时使用左旋多巴和卡比多巴的剂量共同施用时所述组合物在治疗神经变性疾病中的用途。

6. 发明申请

US20220151941A1 PULSED RELEASE CAFFEINE FORMULATIONS AND A PROCESS FOR PREPARATION THEREOF 有权
公开(公告)号：US20220151941A1
公开(公告)日：2022-05-19
申请号：US17436615
申请日：2020-04-28
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Manutosh ACHARYA , Pravin NALAWADE , Munja BAKAN
IPC分类号： A61K9/50 , A23L2/52 , A23F3/14 , A23F3/18 , A23P10/28 , A23P10/35
摘要： The present invention describes pulsed release caffeine formulations comprising caffeine particulate systems prepared by using release retarding agents and at least one or more food grade excipients. The present invention also relates to the process for preparation of caffeine formulations, wherein plurality of particulate systems combined to get the pulsed release caffeine formulation comprising release retarding agents, which provide caffeine release in pulses at different physiological conditions. The pulsed release caffeine formulation is prepared as tablets, capsules, soft gel capsules, caplets, oil suspensions or mixed with nutrient supplements for administration to the subjects. Caffeine formulations as described herein release the caffeine over entire GIT in pulses in a period of 2 to 8 hours and can be administered to subjects for boosting energy, improving concentration, cardiovascular health and for weight management.

7. 发明授权

US10568846B2 Betacryptoxanthin compositions, processes for preparation and uses thereof 有权
公开(公告)号：US10568846B2
公开(公告)日：2020-02-25
申请号：US15140063
申请日：2016-04-27
申请人： OmniActive Health Technologies Limited
发明人： Jayant Deshpande , Abhijit Bhattacharya , Vijaya Juturu , Khadija Ghanam , Vandita Srivastava , Vallabh Mulay
IPC分类号： A61K36/81 , A61K31/045
摘要： Compositions are described that include a betacryptoxanthin extract, rich in trans-betacryptoxanthin, which are prepared by a cost and time effective process and are for use in methods of enhancing cardio-respiratory fitness for physical performance and exercise endurance and to maintain healthy lung function. Betacryptoxanthin extract is prepared by a cost and time effective process of saponification and column chromatography, in which saponification cycle time, solvent amount, column separation time and silica amount are reduced, thus making it industrially viable. Betacryptoxanthin compositions increase exercise time, endurance performance, and lung capacity and maintain healthy lung and cardiovascular function during such physical activities. The compositions also improve physical performance, attenuate muscle fatigue, and enhance aerobic respiration utilization capacity. The compositions are safe for consumption, and can be employed for enhancing cardio-respiratory fitness when administered in an effective amount.

8. 发明授权

US10532035B2 Methods for improvement of visual function and compositions used therein 有权
公开(公告)号：US10532035B2
公开(公告)日：2020-01-14
申请号：US15081272
申请日：2016-03-25
申请人： OmniActive Health Technologies Limited
发明人： Jayant Deshpande , Vijaya Juturu , Khadija Ghanam , Lynda Doyle
IPC分类号： A61K31/047
摘要： Methods herein are described for improvement in visual function by administering macular carotenoid compositions containing an effective daily dose, to a subject in need thereof. More particularly, methods herein are described and include use of the compositions herein by identifying a subject in need thereof, administering a daily dose of lutein and/or zeaxanthin isomers, comprised of meso-zeaxanthin and R,R zeaxanthin, alone or in combination thereof, the composition also including at least one food grade excipient, and evaluating visual performance. The subject is exposed to light of variable wavelengths and intensity and is suffering from visual fatigue. The composition improves contrast sensitivity, glare performance, photo stress recovery, and/or macular pigment optical density, and thus alleviates visual fatigue. The composition is safe for human and other animals for consumption and can be used for improvement in visual health in the subject, when administered in an effective amount.

9. 发明授权

US10301259B2 Beta-cryptoxanthin from plant source and a process for its preparation 有权
公开(公告)号：US10301259B2
公开(公告)日：2019-05-28
申请号：US15663942
申请日：2017-07-31
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Thattaruparambil Krishna Das Sunilkumar , Madapura Lingappiah Shankaranarayana , Padinjarevattom Abdulkadir Sherena , Jeyakodi Shankaranarayanan
IPC分类号： A61K36/00 , C07C403/02 , A61K31/045 , C07C403/24 , C09B61/00 , B01D15/42 , A23L5/44 , A23L33/105
摘要： The present invention provides beta-cryptoxanthin crystals from plant source and a process for its preparation. The present invention particularly relates to a process for the preparation of high purity beta-cryptoxanthin crystals comprising at least about 10% by weight total xanthophylls, of which at least about 75% by weight is trans-beta-cryptoxanthin and the remaining including beta-carotene, and trace amounts of trans-capsanthin and other carotenoids derived from the plant source, including capsicum fruits. The production of beta-cryptoxanthin crystals with high content of trans-beta-cryptoxanthin makes it ideal and suitable for use as a provitamin A source material and also has potential effects on improving bone health and inhibiting bone resorption.

10. 发明授权

US09968565B2 Method for protection and improvement of liver health with meso-zeaxanthin compositions 有权
公开(公告)号：US09968565B2
公开(公告)日：2018-05-15
申请号：US15058823
申请日：2016-03-02
申请人： OMNIACTIVE HEALTH TECHNOLOGIES LIMITED
发明人： Jayant Deshpande , Vijaya Juturu , Abhijit Bhattacharya
IPC分类号： A61K31/047
CPC分类号： A61K31/047
摘要： A method for protection, treatment and improvement of liver health includes administering a meso-zeaxanthin composition in an effective amount to a subject in need thereof. In particular, methods are described of administering a meso-zexanthin composition to a subject fed with high fat diet (HFD), and studying the effect of meso-zeaxanthin for treatment of fatty liver condition, through evaluation of various parameters such as biochemical indicators, anti-inflammatory markers, and nutritional markers.

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