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1. 发明授权

US07736393B2 Artificial dura mater and process for producing the same 失效
标题翻译：人造硬脑膜及其制造方法
公开(公告)号：US07736393B2
公开(公告)日：2010-06-15
申请号：US11578971
申请日：2005-04-18
申请人： Noriaki Shirahama , Tomokazu Mukai , Takao Okada , Yukari Imamura , Yoshimichi Fujiyama
发明人： Noriaki Shirahama , Tomokazu Mukai , Takao Okada , Yukari Imamura , Yoshimichi Fujiyama
IPC分类号： A61F2/02 , A61F2/00 , A61B17/00 , A61L15/10 , C08G63/91 , C08G65/332 , C08G63/08 , C08L67/04
CPC分类号： A61L27/58 , A61L27/18 , A61L2430/32 , Y10S623/926 , C08L67/04
摘要： Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/ε-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2
摘要翻译：本发明提供一种具有至少两层体内可降解聚合物的层压结构的人造硬膜，其至少一层为基材层，所述基材层由乳酸/乙醇酸/己内酯共聚物，共聚物的组分摩尔比为60-85:3-15:10-30摩尔％，共聚物的平均链长满足下述表达式（1）至（3）及其制备方法，当使用这种人造硬膜时，由于缝合孔的膨胀小而导致液体泄漏，并且其保持其强度的时间段适宜地比再生的时间长一点自然硬度，2

2. 发明授权

US5580370A Total heat energy exchanger element preventing a transfer of odors and method of manufacturing same 失效
标题翻译：防止气味转移的总热交换器元件及其制造方法
公开(公告)号：US5580370A
公开(公告)日：1996-12-03
申请号：US51706
申请日：1993-04-26
申请人： Toshimi Kuma , Noriaki Shirahama
发明人： Toshimi Kuma , Noriaki Shirahama
IPC分类号： B32B3/28 , B01D53/04 , B01D53/26 , B01J20/28 , F24F3/14 , F28F3/00 , F28F3/08 , B01D53/02
CPC分类号： B01D53/02 , B01D53/04 , B01D53/06 , B01D53/261 , B01J20/28023 , B01J20/2803 , B01J20/28033 , B01J20/28045 , F24F3/1423 , B01D2253/106 , B01D2253/108 , B01D2253/3425 , F24F2203/1036 , F24F2203/1048 , F24F2203/1068 , F24F2203/108 , F24F2203/1096 , Y10T428/24149 , Y10T428/24694 , Y10T428/24727 , Y10T428/259 , Y10T428/2982
摘要： Adsorbents are used whose equilibrium isotherms for adsorption show no rapid rise in relative humidity more than 40% and whose equilibrium isotherms for adsorption and desorption show no hysteresis phenomenon and in which adsorbed humidity does not cause capillary condensation, for example, A-type or RD-type silica gel or hydrophilic zeolite. Adhesive or binder is applied on the surface of a metallic sheet, a plastic sheet or a ceramic fiber paper, and particulates of the above-mentioned adsorbents are fixed on or in it to get a total heat energy exchanger material. The total heat energy exchanger material is corrugated and laminated to obtain a total heat energy exchanger element. When outer air or return air contains various odorous gases, these odorous gases can be mostly prevented from transferring into supply air through the total heat energy exchanger. When particulates of the above-mentioned adsorbents and chemical blowing agents are mixed in adhesive and said chemical blowing agents are made to blow by heating, the part of adsorbent particulates buried in the adhesive layer can also function as adsorbent through communicating pores and thus total heat energy exchange efficiency can be increased.
摘要翻译：使用吸附剂的吸附平衡等温线不显示相对湿度快速上升超过40％，吸附和解吸的平衡等温线没有滞后现象，吸附湿度不会引起毛细管冷凝，例如A型或RD 型硅胶或亲水性沸石。将粘合剂或粘合剂施加在金属片，塑料片或陶瓷纤维纸的表面上，并将上述吸附剂的颗粒固定在其上或其上以获得总热交换器材料。总热交换器材料是波纹状和层压的，以获得总热交换器元件。当外部空气或回流空气含有各种恶臭气体时，这些恶臭气体可以大部分被防止通过总热能交换器转移到供给空气中。当将上述吸附剂和化学发泡剂的颗粒混合在粘合剂中并且使所述化学发泡剂通过加热而吹动时，埋在粘合剂层中的吸附剂微粒的一部分也可以通过连通的孔而起到吸附剂的作用，从而使总热量能量交换效率可以提高。

3. 发明申请

US20070233275A1 Artificial Dura Mater and Process for Producing the Same 失效
标题翻译：人造硬脑膜及其制造方法
公开(公告)号：US20070233275A1
公开(公告)日：2007-10-04
申请号：US11578971
申请日：2005-04-18
申请人： Noriaki Shirahama , Tomokazu Mukai , Takao Okada , Yukari Imamura , Yoshimichi Fujiyama
发明人： Noriaki Shirahama , Tomokazu Mukai , Takao Okada , Yukari Imamura , Yoshimichi Fujiyama
IPC分类号： A61F2/02
CPC分类号： A61L27/58 , A61L27/18 , A61L2430/32 , Y10S623/926 , C08L67/04
摘要： Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/ε-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2
摘要翻译：本发明提供一种人造硬膜，其具有至少两层体内可降解聚合物的层叠结构，其至少一层为基材层，所述基材层由乳酸/乙醇酸/ε-己内酯共聚物形成，所述共聚物的组分摩尔比为60-85:3-15:10-30摩尔％，所述共聚物的平均链长满足下述表达式（1）至（3）及其制备方法，当使用这种人造硬脑膜时，不会引起液体渗漏，因为缝合孔的膨胀小，并且其保持其强度的时间段适宜地比自动切口再生所需的时间长一点 2， <？in-line-formula description =“In-line formula”end =“lead”？> 1 < L（GA）<[GA％/（LA％+ GA％+ CL％）] xXx0。 58（2）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line-formula description =“In-line Formulas”end =“lead”？> 1 < L（CL）<[CL％/（LA％+ GA％+ CL％）xXx0。其中L（LA），L（GA）和L（CL）表示乳酸单元的平均链长，58（3）<？乙醇酸单元和己内酯单元，LA％，GA％和CL％表示共聚物中乳酸组分，乙醇酸组分己内酯组分的摩尔比，X是共聚物的聚合度。

4. 发明授权

US06441073B1 Biological materials 有权
标题翻译：生物材料
公开(公告)号：US06441073B1
公开(公告)日：2002-08-27
申请号：US09807707
申请日：2001-04-17
申请人： Junzo Tanaka , Masanori Kikuchi , Kimihiro Miyamoto , Shuji Suwa , Shunji Ichikawa , Etsuro Yokoyama , Soichi Shono , Takao Okada , Yukari Imamura , Kazuo Takakuda , Yoshihisa Koyama , Shigeo Tanaka , Noriaki Shirahama , Takatoshi Itoh
发明人： Junzo Tanaka , Masanori Kikuchi , Kimihiro Miyamoto , Shuji Suwa , Shunji Ichikawa , Etsuro Yokoyama , Soichi Shono , Takao Okada , Yukari Imamura , Kazuo Takakuda , Yoshihisa Koyama , Shigeo Tanaka , Noriaki Shirahama , Takatoshi Itoh
IPC分类号： C08K332
CPC分类号： A61L31/127 , A61L27/46 , A61L27/58 , A61L27/54 , A61L27/507 , C08L67/04 , A61L31/18 , A61L31/16
摘要： The followings are disclosed herein: a biomaterial comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone; a biomaterial for the induction of osteoanagenesis, characterized in that a periosteum is attached to the biomaterial comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone; and a biomaterial for the prevention of adhesion comprising calcium phosphate and a copolymer of lactic acid, glycolic acid and &egr;-caprolactone where the molar ratio of lactic acid, glycolic acid and &egr;-caprolactone is within a range of 5-90:3-75:5-40.
摘要翻译：本文公开了以下内容：包含磷酸钙和乳酸，乙醇酸和ε-己内酯的共聚物的生物材料;用于诱导骨诱导成骨的生物材料，其特征在于，将骨膜连接到包含磷酸钙的生物材料和乳酸，乙醇酸和ε-己内酯; 以及乳酸，乙醇酸和ε-己内酯的摩尔比在5-90:3〜75的范围内的防止粘附性的生物材料，包括磷酸钙和乳酸，乙醇酸和ε-己内酯的共聚物：5-40。

5. 再颁专利

USRE37779E1 Adsorber for humidity and odorous gas exchange 有权
标题翻译：吸附器用于湿度和恶臭气体交换
公开(公告)号：USRE37779E1
公开(公告)日：2002-07-02
申请号：US09433271
申请日：1999-11-03
申请人： Toshimi Kuma , Noriaki Shirahama , Hiroaki Izumi
发明人： Toshimi Kuma , Noriaki Shirahama , Hiroaki Izumi
IPC分类号： B32B328
CPC分类号： B32B3/12 , B01D53/02 , B01D53/0438 , B01D53/0446 , B01D53/0454 , B01D53/06 , B01D53/261 , B01D53/28 , B01D2251/302 , B01D2251/40 , B01D2251/60 , B01D2253/106 , B01D2253/108 , B01D2253/202 , B01D2253/206 , B01D2253/25 , B01D2253/304 , B01D2253/3425 , B01D2257/80 , B01D2257/90 , B01D2259/40088 , B01D2259/65 , B32B3/28 , B32B5/18 , B32B19/02 , B32B29/08 , B32B2264/102 , F24F3/1423 , F24F2203/1004 , F24F2203/1036 , F24F2203/1048 , F24F2203/1056 , F24F2203/1068 , F24F2203/1084 , F24F2203/1096 , Y10T428/24372 , Y10T428/24421 , Y10T428/2457 , Y10T428/24579 , Y10T428/24612 , Y10T428/24694 , Y10T428/259 , Y10T428/2911
摘要： In an adsorbing body for humidity and odorous gas exchange such as an adsorbing sheet for dehumidification, an adsorbing element for dehumidification or an adsorbing element for total heat energy exchange, a sheet or a honeycomb laminate is impregnated or coated with silica sol containing, as solid content, not more than 30% of the silica sol weight of minute silica particles not larger than 120 Å in diameter which contain many stable silanol radicals on the surface and 0.01-1% of alkali metal ion Na2O. It is then dried to rigidly fix silica gel. Other humidity adsorbing or absorbing agents such as zeolite, organic high-polymer electrolyte, etc. may be mixed in said silica sol. Silica gel with excellent humidity adsorbing ability can be strongly adhered to a sheet or a honeycomb laminate in an extremely simple method.
摘要翻译：在用于除湿的吸湿片等湿度和恶臭气体交换用吸附体中，除湿用吸附元件或全热能交换用吸附元件，片状或蜂窝状叠层体浸渍或涂覆有含有固体的硅溶胶含量不超过表面含有许多稳定的硅烷醇基团的直径不大于120的二氧化硅微粒的硅溶胶重量的30％，碱金属离子Na 2 O的含量为0.01〜1％。然后将其干燥以使硅胶刚性固定。可以在所述二氧化硅溶胶中混合沸石，有机高分子电解质等其它吸湿剂等吸收剂。以极其简单的方法，能够将具有优异的吸湿能力的硅胶牢固地附着在片材或蜂窝状叠层体上。

6. 发明授权

US5753345A Adsorber for humidity and odorous gas exchange 失效
标题翻译：吸附器用于湿度和恶臭气体交换
公开(公告)号：US5753345A
公开(公告)日：1998-05-19
申请号：US637377
申请日：1996-04-25
申请人： Toshimi Kuma , Noriaki Shirahama , Hiroaki Izumi
发明人： Toshimi Kuma , Noriaki Shirahama , Hiroaki Izumi
IPC分类号： F28D19/04 , B01D53/04 , B01D53/06 , B01D53/26 , B01D53/28 , B01J20/10 , B32B3/12 , B32B3/28 , B32B19/02 , F24F3/14 , B05D3/02
CPC分类号： F24F3/1423 , B01D53/02 , B01D53/06 , B01D53/261 , B01D53/28 , B32B19/02 , B32B3/12 , B32B3/28 , B01D2251/302 , B01D2251/40 , B01D2251/60 , B01D2253/106 , B01D2253/108 , B01D2253/202 , B01D2253/206 , B01D2253/25 , B01D2253/304 , B01D2253/3425 , B01D2257/80 , B01D2257/90 , B01D2259/40088 , B01D2259/65 , B01D53/0438 , B01D53/0446 , B01D53/0454 , F24F2203/1004 , F24F2203/1036 , F24F2203/1048 , F24F2203/1056 , F24F2203/1068 , F24F2203/1084 , F24F2203/1096 , Y10T428/24372 , Y10T428/24421 , Y10T428/2457 , Y10T428/24579 , Y10T428/24612 , Y10T428/24694 , Y10T428/259 , Y10T428/2911
摘要： In an adsorbing body for humidity and odorous gas exchange such as an adsorbing sheet for dehumidification, an adsorbing element for dehumidification or an adsorbing element for total heat energy exchange, a sheet or a honeycomb laminate is impregnated or coated with silica sol containing, as solid content, not more than 30% of the silica sol weight of minute silica particles not larger than 120 .ANG. in diameter which contain many stable silanol radicals on the surface and 0.01-1% of alkali metal ion Na.sub.2 O. It is then dried to rigidly fix silica gel. Other humidity adsorbing or absorbing agents such as zeolite, organic high-polymer electrolyte, etc. may be mixed in said silica sol. Silica gel with excellent humidity adsorbing ability can be strongly adhered to a sheet or a honeycomb laminate in an extremely simple method.
摘要翻译：在用于除湿的吸湿片等湿度和恶臭气体交换用吸附体中，除湿用吸附元件或全热能交换用吸附元件，片状或蜂窝状叠层体浸渍或涂覆有含有固体的硅溶胶含量不超过二氧化硅颗粒的二氧化硅溶胶重量的30％，直径不大于120安培，其表面含有许多稳定的硅烷醇基，0.01-1％的碱金属离子Na2O。然后将其干燥以使硅胶刚性固定。可以在所述二氧化硅溶胶中混合沸石，有机高分子电解质等其它吸湿剂等吸收剂。以极其简单的方法，能够将具有优异的吸湿能力的硅胶牢固地附着在片材或蜂窝状叠层体上。

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