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1. 发明授权

US08349252B2 Vitrified composition which preserves biological materials 有权
标题翻译：保护生物材料的玻璃化组合物
公开(公告)号：US08349252B2
公开(公告)日：2013-01-08
申请号：US12980645
申请日：2010-12-29
申请人： Gloria Elliott , Nilay Chakraborty
发明人： Gloria Elliott , Nilay Chakraborty
IPC分类号： A61L2/00 , A61L2/04 , A61L9/00 , A61L11/00 , C23F11/00
CPC分类号： A01N1/02 , A01N1/0221 , A01N1/0294 , A61L2/0082 , C12N1/04
摘要： The present invention relates to a method for preserving biological material comprising the steps of: providing a vitrification solution comprised of the biological material and a vitrification agent where the solution has a temperature in the range from 0.1° C. to 17.9° C.; microwaving the vitrification solution for a first period of time; allowing the vitrification solution to rest for a second period of time; repeating steps b and c until the vitrification solution enters into a glassy state.
摘要翻译：本发明涉及一种保存生物材料的方法，包括以下步骤：提供由生物材料和玻璃化剂组成的玻璃化溶液，其中溶液的温度范围为0.1℃至17.9℃; 在第一时间内微波玻璃化溶液; 允许玻璃化溶液休息一段时间; 重复步骤b和c，直到玻璃化溶液进入玻璃状态。

2. 发明申请

US20090288479A1 STANDING WAVE FLUIDIC AND BIOLOGICAL TOOLS 审中-公开
标题翻译：标准波流体和生物工具
公开(公告)号：US20090288479A1
公开(公告)日：2009-11-26
申请号：US12395213
申请日：2009-02-27
申请人： SHANE C. WOODY , Bethany A. Woody , Marcin B. Bauza , Stuart T. Smith , Nilay Chakraborty
发明人： SHANE C. WOODY , Bethany A. Woody , Marcin B. Bauza , Stuart T. Smith , Nilay Chakraborty
IPC分类号： G01B5/28
CPC分类号： B01F11/0088 , B01F13/0059 , B81B3/0027 , B81B2201/0292 , B81B2201/038 , B82Y15/00 , G01N11/162 , G01N2203/0286
摘要： The present invention provides standing wave fluidic and biological tools, including: at least one elongated fiber that has mesoscale (i.e. milliscale), microscale, nanoscale, or picoscale dimensions, the at least one elongated fiber having a first end and a second end; and an actuator coupled to the first end of the at least one elongated fiber, wherein the actuator is operable for applying oscillation cycles to the at least one elongated fiber in one or more directions, and wherein the actuator is operable for generating a standing wave in the at least one elongated fiber. These standing wave fluidic and biological tools are selectively disposed in a fluid to provide a function such as mixing the fluid, measuring the viscosity of the fluid, attracting particles in the fluid, shepherding particles in the fluid, providing propulsive force in the fluid, pumping the fluid, dispensing the fluid, sensing particles in the fluid, and detecting particles in the fluid, among others.
摘要翻译：本发明提供了驻波流体学和生物学工具，其包括：至少一种细长纤维，其具有中尺度（即，微米），微米级，纳米级或者尺寸尺寸，所述至少一种细长纤维具有第一端和第二端; 以及联接到所述至少一个细长光纤的第一端的致动器，其中所述致动器可操作以在一个或多个方向上对所述至少一根细长光纤施加振荡周期，并且其中所述致动器可操作以产生驻波所述至少一根细长纤维。这些驻波流体和生物工具选择性地设置在流体中以提供诸如混合流体，测量流体的粘度，吸引流体中的颗粒，流体中的游牧颗粒，在流体中提供推进力的泵送流体，分配流体，感测流体中的颗粒，以及检测流体中的颗粒等。

3. 发明申请

US20110165553A1 VITRIFIED COMPOSITION WHICH PRESERVES BIOLOGICAL MATERIALS 有权
标题翻译：保护生物材料的维生素组合物
公开(公告)号：US20110165553A1
公开(公告)日：2011-07-07
申请号：US12980645
申请日：2010-12-29
申请人： Gloria Elliott , Nilay Chakraborty
发明人： Gloria Elliott , Nilay Chakraborty
IPC分类号： A01N1/02 , A01N1/00 , C12N7/00 , C12N5/00 , C12N1/20 , C12N1/14 , C12N1/12 , C07K14/00
CPC分类号： A01N1/02 , A01N1/0221 , A01N1/0294 , A61L2/0082 , C12N1/04
摘要： The present invention relates to a method for preserving biological material comprising the steps of: providing a vitrification solution comprised of the biological material and a vitrification agent where the solution has a temperature in the range from 0.1° C. to 17.9° C.; microwaving the vitrification solution for a first period of time; allowing the vitrification solution to rest for a second period of time; repeating steps b and c until the vitrification solution enters into a glassy state.
摘要翻译：本发明涉及一种保存生物材料的方法，包括以下步骤：提供由生物材料和玻璃化剂组成的玻璃化溶液，其中溶液的温度范围为0.1℃至17.9℃; 在第一时间内微波玻璃化溶液; 允许玻璃化溶液休息一段时间; 重复步骤b和c，直到玻璃化溶液进入玻璃状态。

4. 发明授权

US07883664B2 Microwave drying process for vitrification of biologics 有权
标题翻译：用于生物制剂玻璃化的微波干燥过程
公开(公告)号：US07883664B2
公开(公告)日：2011-02-08
申请号：US11769249
申请日：2007-06-27
申请人： Gloria Elliott , Nilay Chakraborty
发明人： Gloria Elliott , Nilay Chakraborty
IPC分类号： A61L2/00 , H05B6/64 , H05B6/80
CPC分类号： A61L2/0082 , A01N1/02 , A01N1/0221
摘要： The present invention relates to a biological composition which is storable above cryogenic temperature which is comprised of a vitrification solution in a glassy state. The vitrification solution is comprised of a biological material and a vitrification agent.
摘要翻译：本发明涉及一种生物组合物，其可存储在低温温度下，其由玻璃态的玻璃化溶液组成。玻璃化溶液由生物材料和玻璃化剂组成。

5. 发明申请

US20090004048A1 VITRIFIED COMPOSITION WHICH PRESERVES BIOLOGICAL MATERIALS 有权
标题翻译：保护生物材料的维生素组合物
公开(公告)号：US20090004048A1
公开(公告)日：2009-01-01
申请号：US11769249
申请日：2007-06-27
申请人： Gloria Elliott , Nilay Chakraborty
发明人： Gloria Elliott , Nilay Chakraborty
IPC分类号： A01N1/02 , A61L2/16 , C09K3/00 , C12N1/00
CPC分类号： A61L2/0082 , A01N1/02 , A01N1/0221
摘要： The present invention relates to a biological composition which is storable above cryogenic temperature which is comprised of a vitrification solution in a glassy state. The vitrification solution is comprised of a biological material and a vitrification agent.
摘要翻译：本发明涉及一种生物组合物，其可存储在低温温度下，其由玻璃态的玻璃化溶液组成。玻璃化溶液由生物材料和玻璃化剂组成。

6. 发明申请

US20130260452A1 Methods For The Cryopreservation Of Mammalian Cells 审中-公开
标题翻译：哺乳动物细胞冷冻保存方法
公开(公告)号：US20130260452A1
公开(公告)日：2013-10-03
申请号：US13501381
申请日：2010-10-18
申请人： Mehmet Toner , Heidi Y. Elmoazzen , Thomas L. Toth , Yunseok Heo , Ho-Joon Lee , Nilay Chakraborty
发明人： Mehmet Toner , Heidi Y. Elmoazzen , Thomas L. Toth , Yunseok Heo , Ho-Joon Lee , Nilay Chakraborty
IPC分类号： G01N1/42
CPC分类号： C12N1/04 , A01N1/0268 , A01N1/0284 , G01N1/42
摘要： Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.
摘要翻译：制造的毛细管可以包括：管状构件; 以及部分地覆盖管状构件的涂层，该涂层限定一个窗口，其中管状构件没有涂层。包含的试剂盒和与毛细管有关的方法可用于细胞的低温保存。

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