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1. 发明授权

US08685293B1 Control of particle formation at the nanoscale 失效
标题翻译：在纳米尺度下控制颗粒形成
公开(公告)号：US08685293B1
公开(公告)日：2014-04-01
申请号：US13053119
申请日：2011-03-21
申请人： Nicholas V. Coppa , Robert J. Levis
发明人： Nicholas V. Coppa , Robert J. Levis
IPC分类号： B29C35/08 , B29B9/00
CPC分类号： B23K26/03 , B23K26/0624 , B23K26/064 , B23K26/361 , B23K26/40 , B23K2101/04 , B23K2103/10 , B23K2103/50 , B29B9/16 , B29B2009/125
摘要： Our invention allows for control of particle formation at the nanoscale, providing a means to control nanoparticle and nanostructure formation using feedback on the fly from nanoparticle characteristic analysis and optimization/knowledge extraction control algorithms. A closed loop feedback controller causes the interaction of a shaped flaser pulse with a substrate. The substrate can be one or more solid, liquid or gas or any combination thereof. Nanoparticles are produced and their characteristics are measured. The measured characteristics are compared with the desired nanoparticle characteristics. If the measured and desired characteristics are not equivalent, the closed loop feedback controller modifies the shape of the laser pulse and the next cycle begins. With successive loop of the control process the difference between the desired and measured characteristics converges until they are equivalent. At the end of the process a relationship is developed between the desired nanoparticle characteristics and the laser pulse shape. A catalog of all pulse shapes generated and the resulting nanoparticle characteristics is generated each time the processor is cycled whether or not the nanoparticle characteristics are those desired.
摘要翻译：我们的发明允许在纳米尺度下控制颗粒形成，提供了使用纳米颗粒特征分析和优化/知识提取控制算法的飞行反馈来控制纳米颗粒和纳米结构形成的手段。闭环反馈控制器导致成形的激光脉冲与衬底的相互作用。基底可以是一种或多种固体，液体或气体或其任何组合。产生纳米颗粒并测量它们的特性。将测量的特性与期望的纳米颗粒特性进行比较。如果测量和期望的特性不相等，则闭环反馈控制器修改激光脉冲的形状，并开始下一个循环。在控制过程的连续循环中，期望和测量特性之间的差异收敛，直到它们相等。在该过程结束时，在所需的纳米颗粒特性和激光脉冲形状之间形成关系。生成所有脉冲形状的目录，并且每次处理器循环时都产生所得纳米粒子特征，无论纳米粒子特征是否为所需的那些。

2. 发明申请

US20090197085A1 ORGANIC NANOPARTICLES AND METHOD OF PREPARATION THEREOF 审中-公开
标题翻译：有机纳米颗粒及其制备方法
公开(公告)号：US20090197085A1
公开(公告)日：2009-08-06
申请号：US12309890
申请日：2007-08-06
申请人： Nicholas V. Coppa
发明人： Nicholas V. Coppa
IPC分类号： B32B5/02 , C07D307/62
CPC分类号： A61K9/14 , A61K31/34 , Y10T428/2982
摘要： The invention relates to organic nanopowders and methods for their production, including ascorbic acid nanoparticles and nanopowder salts of ascorbic acid, such as, calcium ascorbate nanopowders. Such organic nanopowders may have utility in cosmetics, pharmaceutical preparations and nutrition. The invention additionally relates to methods for producing ascorbic acid nanoparticles and calcium ascorbate nanopowders. The method of preparation of ascorbic acid or calcium ascorbate nanopowders involves: (i) preparing an solution including an organic compound solute and a solvent to disperse or dissolve the organic compound, and (ii) removal or separation of the solvent in such a manner so as to limit the growth of the organic solute particles to nanometer range which is typically below 500 nm but preferably 100 nm or less.
摘要翻译：本发明涉及有机纳米粉末及其生产方法，包括抗坏血酸纳米颗粒和抗坏血酸的纳米粉末盐，如抗坏血酸钙纳米粉末。这样的有机纳米粉末可用于化妆品，药物制剂和营养。本发明还涉及生产抗坏血酸纳米颗粒和抗坏血酸钙纳米粉末的方法。制备抗坏血酸或抗坏血酸钙纳米粉体的方法包括：（i）制备包括有机化合物溶质和溶剂的溶液以分散或溶解有机化合物，和（ii）以这样的方式除去或分离溶剂以将有机溶质颗粒的生长限制在通常低于500nm但优选100nm或更小的纳米范围内。

3. 发明授权

US5238913A Superconducting microcircuitry by the microlithgraphic patterning of superconducting compounds and related materials 失效
标题翻译：超导微电路通过微结构图案化超导化合物及相关材料
公开(公告)号：US5238913A
公开(公告)日：1993-08-24
申请号：US860337
申请日：1992-03-30
申请人： Nicholas V. Coppa
发明人： Nicholas V. Coppa
IPC分类号： H05K1/09 , H01L39/24 , H05K3/14
CPC分类号： H01L39/2464 , Y10S505/725 , Y10S505/728 , Y10S505/742
摘要： Superconducting microcircuits including a thin layer of Ba.sub.2 Cu.sub.3 O.sub.5+x (0
摘要翻译：在衬底上包括Ba2Cu3O5 + x（0

4. 发明授权

US06311409B1 Freeze drying apparatus 失效
标题翻译：冷冻干燥装置
公开(公告)号：US06311409B1
公开(公告)日：2001-11-06
申请号：US09255581
申请日：1999-02-22
申请人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
发明人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
IPC分类号： F26B506
CPC分类号： F26B5/06
摘要： The present invention provides methods and apparatus for freeze drying in which a solution, which can be a radioactive salt dissolved within an acid, is frozen into a solid on vertical plates provided within a freeze drying chamber. The solid is sublimated into vapor and condensed in a cold condenser positioned above the freeze drying chamber and connected thereto by a conduit. The vertical positioning of the cold condenser relative to the freeze dryer helps to help prevent substances such as radioactive materials separated from the solution from contaminating the cold condenser. Additionally, the system can be charged with an inert gas to produce a down rush of gas into the freeze drying chamber to also help prevent such substances from contaminating the cold condenser.
摘要翻译：本发明提供了一种用于冷冻干燥的方法和装置，其中可将溶解在酸中的放射性盐的溶液在冷冻干燥室内的垂直板上冷冻成固体。将固体升华成蒸汽并在位于冷冻干燥室上方的冷凝器中冷凝并通过导管与其连接。冷凝器相对于冷冻干燥机的垂直定位有助于防止从溶液中分离的放射性物质等物质污染冷凝器。此外，该系统可以带有惰性气体，以产生气体进入冷冻干燥室的下冲，也有助于防止这些物质污染冷凝器。

5. 发明授权

US5996248A Freeze drying method 失效
标题翻译：冷冻干燥方法
公开(公告)号：US5996248A
公开(公告)日：1999-12-07
申请号：US716008
申请日：1996-09-19
申请人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
发明人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
IPC分类号： G21F9/08 , F26B5/06 , G21F9/14 , F26B5/04
CPC分类号： F26B5/06
摘要： The present invention provides methods and apparatus for freeze drying in which a solution, which can be a radioactive salt dissolved within an acid, is frozen into a solid on vertical plates provided within a freeze drying chamber. The solid is sublimated into vapor and condensed in a cold condenser positioned above the freeze drying chamber and connected thereto by a conduit. The vertical positioning of the cold condenser relative to the freeze dryer helps to help prevent substances such as radioactive materials separated from the solution from contaminating the cold condenser. Additionally, the system can be charged with an inert gas to produce a down rush of gas into the freeze drying chamber to also help prevent such substances from contaminating the cold condenser.
摘要翻译：本发明提供了一种用于冷冻干燥的方法和装置，其中可将溶解在酸中的放射性盐的溶液在冷冻干燥室内的垂直板上冷冻成固体。将固体升华成蒸汽并在位于冷冻干燥室上方的冷凝器中冷凝并通过导管与其连接。冷凝器相对于冷冻干燥机的垂直定位有助于防止从溶液中分离的放射性物质等物质污染冷凝器。此外，该系统可以带有惰性气体，以产生气体进入冷冻干燥室的下冲，也有助于防止这些物质污染冷凝器。

6. 发明授权

US5350569A Storage of nuclear materials by encapsulation in fullerenes 失效
标题翻译：通过包封在富勒烯中储存核材料
公开(公告)号：US5350569A
公开(公告)日：1994-09-27
申请号：US39668
申请日：1993-03-30
申请人： Nicholas V. Coppa
发明人： Nicholas V. Coppa
IPC分类号： C01B31/02 , G21F9/00 , C01B31/00
CPC分类号： B82Y30/00 , B82Y40/00 , C01B31/0206 , C01B31/0213 , G21F9/00 , Y10S977/736 , Y10S977/903
摘要： A method of encapsulating radioactive materials inside fullerenes for stable long-term storage. Fullerenes provide a safe and efficient means of disposing of nuclear waste which is extremely stable with respect to the environment. After encapsulation, a radioactive ion is essentially chemically isolated from its external environment.
摘要翻译：将放射性物质包裹在富勒烯内部以保持长期储存的方法。富勒烯提供了一种安全有效的处理对环境非常稳定的核废料的手段。封装后，放射性离子基本上与其外界环境化学分离。

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