专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06311409B1 Freeze drying apparatus 失效
标题翻译：冷冻干燥装置
公开(公告)号：US06311409B1
公开(公告)日：2001-11-06
申请号：US09255581
申请日：1999-02-22
申请人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
发明人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
IPC分类号： F26B506
CPC分类号： F26B5/06
摘要： The present invention provides methods and apparatus for freeze drying in which a solution, which can be a radioactive salt dissolved within an acid, is frozen into a solid on vertical plates provided within a freeze drying chamber. The solid is sublimated into vapor and condensed in a cold condenser positioned above the freeze drying chamber and connected thereto by a conduit. The vertical positioning of the cold condenser relative to the freeze dryer helps to help prevent substances such as radioactive materials separated from the solution from contaminating the cold condenser. Additionally, the system can be charged with an inert gas to produce a down rush of gas into the freeze drying chamber to also help prevent such substances from contaminating the cold condenser.
摘要翻译：本发明提供了一种用于冷冻干燥的方法和装置，其中可将溶解在酸中的放射性盐的溶液在冷冻干燥室内的垂直板上冷冻成固体。将固体升华成蒸汽并在位于冷冻干燥室上方的冷凝器中冷凝并通过导管与其连接。冷凝器相对于冷冻干燥机的垂直定位有助于防止从溶液中分离的放射性物质等物质污染冷凝器。此外，该系统可以带有惰性气体，以产生气体进入冷冻干燥室的下冲，也有助于防止这些物质污染冷凝器。

2. 发明授权

US5996248A Freeze drying method 失效
标题翻译：冷冻干燥方法
公开(公告)号：US5996248A
公开(公告)日：1999-12-07
申请号：US716008
申请日：1996-09-19
申请人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
发明人： Nicholas V. Coppa , Paul Stewart , Ernesto Renzi
IPC分类号： G21F9/08 , F26B5/06 , G21F9/14 , F26B5/04
CPC分类号： F26B5/06
摘要： The present invention provides methods and apparatus for freeze drying in which a solution, which can be a radioactive salt dissolved within an acid, is frozen into a solid on vertical plates provided within a freeze drying chamber. The solid is sublimated into vapor and condensed in a cold condenser positioned above the freeze drying chamber and connected thereto by a conduit. The vertical positioning of the cold condenser relative to the freeze dryer helps to help prevent substances such as radioactive materials separated from the solution from contaminating the cold condenser. Additionally, the system can be charged with an inert gas to produce a down rush of gas into the freeze drying chamber to also help prevent such substances from contaminating the cold condenser.
摘要翻译：本发明提供了一种用于冷冻干燥的方法和装置，其中可将溶解在酸中的放射性盐的溶液在冷冻干燥室内的垂直板上冷冻成固体。将固体升华成蒸汽并在位于冷冻干燥室上方的冷凝器中冷凝并通过导管与其连接。冷凝器相对于冷冻干燥机的垂直定位有助于防止从溶液中分离的放射性物质等物质污染冷凝器。此外，该系统可以带有惰性气体，以产生气体进入冷冻干燥室的下冲，也有助于防止这些物质污染冷凝器。

3. 发明申请

US20060207122A1 Freeze dryer 审中-公开
标题翻译：冷冻干燥机
公开(公告)号：US20060207122A1
公开(公告)日：2006-09-21
申请号：US11080596
申请日：2005-03-15
申请人： Paul Stewart , Ernesto Renzi
发明人： Paul Stewart , Ernesto Renzi
IPC分类号： F26B25/00 , F26B5/06
CPC分类号： F26B25/12 , F16J15/008 , F16J15/46 , F26B5/06
摘要： A freeze dryer comprises a chamber having an opening through which containers can be inserted into the chamber, a door, and a mechanism for moving the door against the opening. A sealing mechanism comprises a first gasket extending around the opening, and a second gasket extending around the first gasket. The second gasket is moveable between a first position at which the first gasket forms an airtight seal with the door and a second position at which the second gasket forms an airtight seal with the door.
摘要翻译：冷冻干燥机包括具有开口的室，容器可以通过该开口插入室中，门和用于使门相对于开口移动的机构。密封机构包括围绕开口延伸的第一垫圈和围绕第一垫圈延伸的第二垫圈。第二垫圈可在第一垫圈与门之间形成气密密封的第一位置和第二垫圈与门形成气密密封的第二位置之间移动。

4. 发明申请

US20070022622A1 Freeze drying apparatus 审中-公开
标题翻译：冷冻干燥装置
公开(公告)号：US20070022622A1
公开(公告)日：2007-02-01
申请号：US11189532
申请日：2005-07-26
申请人： Ivan Lanaway , Ernesto Renzi
发明人： Ivan Lanaway , Ernesto Renzi
IPC分类号： F26B13/30 , F26B5/04
CPC分类号： F26B25/12 , F26B5/06 , F26B25/066
摘要： Freeze drying apparatus is described, the freeze drying apparatus comprising freezing apparatus for freezing a liquid component of a sample into a solid, a mobile drying chamber for receiving samples from the freezing apparatus, a condensation chamber comprising a condenser, a condenser conduit system comprising an outlet connected to the condensation chamber, an inlet for connection to the drying chamber, and an isolation valve for selectively isolating the inlet from the outlet, an evacuation system for evacuating the drying chamber, and a thermal control system for controlling the temperature of the samples located within the drying chamber. The drying chamber is moveable between a first location at which samples are transferred from the freezing apparatus to the chamber, and a second location at which the chamber is connected to the inlet of the condenser conduit system.
摘要翻译：描述了冷冻干燥设备，该冷冻干燥设备包括用于将样品的液体组分冷冻成固体的冷冻设备，用于从冷冻设备接收样品的移动干燥室，包括冷凝器的冷凝室，包括冷凝器的冷凝器管道系统连接到冷凝室的出口，用于连接到干燥室的入口和用于选择性地将入口与出口隔离的隔离阀，用于抽空干燥室的抽空系统和用于控制样品的温度的热控制系统位于干燥室内。干燥室可以在样品从冷冻装置转移到室之间的第一位置和室连接到冷凝器管道系统的入口的第二位置之间移动。

5. 发明授权

US08640358B2 Freeze dryer slot door actuator and method 失效
标题翻译：冷冻干燥器槽门执行器和方法
公开(公告)号：US08640358B2
公开(公告)日：2014-02-04
申请号：US13131949
申请日：2009-12-15
申请人： Francis W. DeMarco , Ernesto Renzi
发明人： Francis W. DeMarco , Ernesto Renzi
IPC分类号： F26B11/02
CPC分类号： F26B5/06 , F26B25/12
摘要： Movement of a slot door of a freeze dryer is driven by a rack and pinion actuator. The actuator is easily sanitized and includes internal elements that are accessible to sanitizing sprays. The pinions are driven by pinion shafts that pass through a seal separating an aseptic area from a non-aseptic area where the drive train is positioned. Only rotary motion is transferred across the aseptic barrier, reducing the need for a bellows or sliding covers, which are difficult to sanitize.
摘要翻译：冷冻干燥机的狭槽门的移动由齿条和小齿轮致动器驱动。致动器易于消毒，并且包括可以消毒喷雾剂的内部元件。小齿轮由小齿轮轴驱动，齿轮轴穿过将无菌区域与传动系定位的非无菌区域分开的密封件。只有旋转运动才能跨越无菌屏障传递，减少了对波纹管或滑盖的需求，这些难以消毒。

6. 发明授权

US5783156A Transfer port system between sterile environments 失效
标题翻译：无菌环境之间的转运系统
公开(公告)号：US5783156A
公开(公告)日：1998-07-21
申请号：US682250
申请日：1996-07-17
申请人： Ernesto Renzi , Johannes W. Krikhaar
发明人： Ernesto Renzi , Johannes W. Krikhaar
IPC分类号： B65B55/04 , B01L1/02 , B65D81/20 , F26B5/06 , A61L2/04 , B01L1/00 , B01L11/02
CPC分类号： F26B5/06 , B01L1/02
摘要： A transfer port system between two sterile environments having docked and undocked positions which is made up of two door frames connected to the environments and two doors connected to the two door frames. When the sterile environments are in the docked position the door frames of the two doors are juxtaposed and in close physical contact with one another and when the two sterile environments are in the undocked position the two door frames are spaced apart from one another and the two doors seal the sterile environments. The two door frames and the doors have a potentially non-sterile peripheral juncture located at the juncture between the doors and door frames when the doors are in a closed position sealing the sterile environments when the sterile environments are in their docked position. In order to sterilize this non-sterile peripheral junction, one or both of the door frames is provided with internal channels for circulation of a heat transfer fluid to heat the two door frames and the two doors and thereby sterilize said juncture. A vacuum sealing gasket is provided to allow a vacuum to be pulled between the two doors to hold the two doors together when the sterile environments are in the docked position. The two doors are then rotated as a unit between a closed position sealing the two sterile environments and an opened position away from the two door frames permitting transport through the two door frames and between the sterile environments.
摘要翻译：两个无菌环境之间的转接口系统，具有停靠和离开的位置，该两个不连接的位置由连接到环境的两个门框和连接到两个门框的两个门构成。当无菌环境处于对接位置时，两个门的门框并置并且彼此紧密地物理接触，并且当两个无菌环境处于脱离位置时，两个门框彼此间隔开，并且两个门框门密封无菌环境。当门处于关闭位置时，当无菌环境处于对接位置时，两个门框和门具有位于门和门框之间的接合处的潜在的非无菌外围接合处。为了对这种非无菌外围连接件进行消毒，一个或两个门框设置有用于循环传热流体的内部通道，用于加热两个门框和两个门，从而对所述接合部进行消毒。提供真空密封垫圈以允许在两个门之间拉动真空，以在无菌环境处于对接位置时将两个门保持在一起。然后将两个门作为一个单元旋转，在密封两个无菌环境的关闭位置和离开两个门框的打开位置之间允许运输通过两个门框架和无菌环境之间。

7. 发明申请

US20110232123A1 Freeze Dryer Slot Door Actuator and Method 失效
标题翻译：冷冻干燥器门执行器和方法
公开(公告)号：US20110232123A1
公开(公告)日：2011-09-29
申请号：US13131949
申请日：2009-12-15
申请人： Francis W DeMarco , Ernesto Renzi
发明人： Francis W DeMarco , Ernesto Renzi
IPC分类号： F26B5/06
CPC分类号： F26B5/06 , F26B25/12
摘要： Movement of a slot door of a freeze dryer is driven by a rack and pinion actuator. The actuator is easily sanitized and includes internal elements that are accessible to sanitizing sprays. The pinions are driven by pinion shafts that pass through a seal separating an aseptic area from a non-aseptic area where the drive train is positioned. Only rotary motion is transferred across the aseptic barrier, reducing the need for a bellows or sliding covers, which are difficult to sanitize.
摘要翻译：冷冻干燥机的狭槽门的移动由齿条和小齿轮致动器驱动。致动器易于消毒，并且包括可以消毒喷雾剂的内部元件。小齿轮由小齿轮轴驱动，齿轮轴穿过将无菌区域与传动系定位的非无菌区域分开的密封件。只有旋转运动才能跨越无菌屏障传递，减少了对波纹管或滑盖的需求，这些难以消毒。

8. 发明申请

US20100242300A1 FREEZE DRYER BARRIER SYSTEM 审中-公开
标题翻译：冷冻干燥机系统
公开(公告)号：US20100242300A1
公开(公告)日：2010-09-30
申请号：US12514067
申请日：2007-11-01
申请人： David Debo , Ernesto Renzi , Francis W. DeMarco
发明人： David Debo , Ernesto Renzi , Francis W. DeMarco
IPC分类号： F26B5/06 , F26B19/00 , B23P19/04
CPC分类号： F26B5/06 , F26B25/008 , Y10T29/53
摘要： This invention is directed to freeze dryers used in the pharmaceutical industry, and in particular, to a barrier system for freeze dryers located in an isolator or clean room facilitate sterilization of the isolator.
摘要翻译：本发明涉及制药工业中使用的冷冻干燥机，尤其涉及一种位于隔离器或洁净室中的用于冷冻干燥器的阻隔系统，促进隔离器的灭菌。

9. 发明申请

US20070294912A1 Integrated heater/cooler 审中-公开
标题翻译：集成加热器/冷却器
公开(公告)号：US20070294912A1
公开(公告)日：2007-12-27
申请号：US11801147
申请日：2007-05-09
申请人： Ernesto Renzi , David Debo , Francis Demarco
发明人： Ernesto Renzi , David Debo , Francis Demarco
IPC分类号： F26B25/06 , F26B5/06
CPC分类号： F28D7/0066 , F28D7/0083 , F28D7/024 , F28D2021/0077
摘要： An integrated heater/cooler for heating and cooling of heat transfer fluid in a freeze dryer is provided. This integrated heater/cooler is made up on a housing having a heat exchange fluid outlet to discharge heat exchange fluid; a heat exchanger disposed on one side of the housing having a refrigerant inlet to receive refrigerant, a refrigerant outlet to discharge refrigerant and a heat exchange fluid inlet to receive heat exchange fluid; and a heater disposed on the other side of the housing.
摘要翻译：提供了一种用于在冷冻干燥器中加热和冷却传热流体的集成加热器/冷却器。该集成加热器/冷却器由具有热交换流体出口的壳体构成以排出热交换流体; 设置在壳体一侧的热交换器，具有用于接收制冷剂的制冷剂入口，用于排出制冷剂的制冷剂出口和用于接收热交换流体的热交换流体入口; 以及设置在所述壳体的另一侧上的加热器。

10. 发明申请

US20050198856A1 Freeze dryer 有权
标题翻译：冷冻干燥机
公开(公告)号：US20050198856A1
公开(公告)日：2005-09-15
申请号：US10796943
申请日：2004-03-10
申请人： Frans Damen , Francis DeMarco , Ernesto Renzi
发明人： Frans Damen , Francis DeMarco , Ernesto Renzi
IPC分类号： E05D15/58 , F26B5/06 , F26B25/12 , F26B13/30 , F26B19/00
CPC分类号： F26B5/06 , F26B25/12
摘要： A freeze dryer comprising a chamber having a rectangular slot through which vials are inserted into the chamber, and a slot door for forming a seal with the chamber to close the slot. To enable the vials to be subsequently removed from the chamber, the slot door is raised. As the door is raised, it is rotated to expose the rear surface of the door for cleaning purposes.
摘要翻译：一种冷冻干燥机，包括具有矩形狭缝的室，小瓶通过所述矩形狭槽插入到所述室中，以及狭槽门，用于与所述室形成密封以封闭所述狭槽。为了使小瓶随后从腔室中取出，槽门升高。当门升起时，它被旋转以暴露门的后表面用于清洁目的。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式