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1. 发明授权

US6162395A Sterilization of elongate lumens 失效
标题翻译：细菌腔的灭菌
公开(公告)号：US6162395A
公开(公告)日：2000-12-19
申请号：US135146
申请日：1998-08-17
申请人： Nicholas Kowanko
发明人： Nicholas Kowanko
IPC分类号： A61B1/12 , A61L2/20 , A61L2/00
CPC分类号： A61L2/208 , A61B1/125 , A61L2/204 , A61L2/206 , A61L2202/122 , A61L2202/24
摘要： A method of and system for sterilizing the internal surfaces of one or more elongate relatively narrow passages of interest contained in a device of interest, said passages having end openings and being susceptible of sustaining flow therealong by inducing a positive flow of sterilizing gas through each passage of interest in a selected direction. Gas flow through a device of interest is caused by a passive two-chamber device which generates a transient pressure gradient between the ends of the lumens of the device in response to externally imposed variations of pressure. Sterilant gas is provided from outside the two chamber systems.
摘要翻译：一种用于对感兴趣的装置中包含的一个或多个细长的相对狭窄的感兴趣的通道的内表面进行消毒的方法和系统，所述通道具有端部开口，并且通过诱导通过每个通道的消毒气体的正向流动而容易地保持其流动对所选方向感兴趣。通过感兴趣的装置的气体流动是由无源双室装置引起的，其在响应于外部施加的压力变化而在装置的流明端部之间产生瞬时压力梯度。从两个室系统的外部提供灭菌气体。

2. 发明授权

US5385606A Adhesive composition and method 失效
标题翻译：粘合剂组合物和方法
公开(公告)号：US5385606A
公开(公告)日：1995-01-31
申请号：US34184
申请日：1993-03-22
申请人： Nicholas Kowanko
发明人： Nicholas Kowanko
IPC分类号： A61L24/00 , A61L24/04 , A61L24/10 , C09J189/00 , C08L89/00 , C08H1/02
CPC分类号： C09J189/00 , A61L24/043 , A61L24/106
摘要： An adhesive composition, primarily intended as a tissue adhesive, comprised of cross-linked proteinaceous material, and methods for its use.
摘要翻译：主要用作组织粘合剂的由交联的蛋白质材料组成的粘合剂组合物及其使用的方法。

3. 发明授权

US06312646B2 Sterilization of elongate lumens 失效
公开(公告)号：US06312646B2
公开(公告)日：2001-11-06
申请号：US09725976
申请日：2000-11-29
申请人： Nicholas Kowanko
发明人： Nicholas Kowanko
IPC分类号： A01N100
CPC分类号： A61L2/204 , A61B1/125 , A61L2/206 , A61L2/208 , A61L2202/122 , A61L2202/24
摘要： A method of and system for sterilizing the internal surfaces of one or more elongate relatively narrow passages of interest contained in a device of interest, said passages having end openings and being susceptible of sustaining flow there along by inducing a positive flow of sterilizing gas through each passage of interest in a selected direction. Gas flow through a device of interest is caused by a passive two-chamber device which generates a transient pressure gradient between the ends of the lumens of the device in response to externally imposed variations of pressure. Sterilant gas is provided from outside the two chamber systems.

4. 发明授权

US6036918A Vapor sterilization 失效
标题翻译：蒸气灭菌
公开(公告)号：US6036918A
公开(公告)日：2000-03-14
申请号：US32606
申请日：1993-03-17
申请人： Nicholas Kowanko
发明人： Nicholas Kowanko
IPC分类号： A01N37/16 , A61L2/20
CPC分类号： A61L2/208 , A01N37/16 , A61L2/202 , A61L2202/122 , A61L2202/24
摘要： The present invention discloses the use of peracid vapor as a sterilant. A process is disclosed for sterilizing a load by exposure to peracid vapor, the load being disposed in a sterilization chamber adapted to contain the peracid vapor, including the steps of exposing the load to the peracid vapor in the sterilization chamber at reduced pressure, i.e., below atmospheric pressure and introducing a quantity of another gas, the gas being of a type which does not interfere with the sterilization procedure, to increase the pressure in the chamber to a value above that at which the chamber was when the peracid vapor alone was present but below atmospheric pressure, whereby the penetration of any vapor penetrable portions of the load to be sterilized by the peracid vapor is enhanced.
摘要翻译：本发明公开了使用过酸蒸气作为灭菌剂。公开了一种通过暴露于过酸蒸气对负载进行消毒的方法，该负载被设置在适于容纳过酸蒸汽的消毒室中，包括以下步骤：将负载暴露于消毒室中的过酸蒸气中，低于大气压，并引入一定量的另外的气体，气体是不干扰灭菌程序的气体，以将室内的压力增加到高于单独存在过酸蒸气时室的温度但低于大气压，从而增强了由过酸蒸气灭菌的负载的任何蒸气穿透部分的穿透。

5. 发明授权

US4003941A Process for producing polyhalocarbons oxides 失效
标题翻译：生产多卤代烃氧化物的方法
公开(公告)号：US4003941A
公开(公告)日：1977-01-18
申请号：US360905
申请日：1973-05-16
申请人： George H. Crawford , Nicholas Kowanko
发明人： George H. Crawford , Nicholas Kowanko
IPC分类号： C08G65/00 , C08G67/00 , C07C43/17
CPC分类号： C08G65/007
摘要： A process for the production of polyhalocarbon oxides not requiring the use of light is disclosed. This process involves introducing into a reaction zone perhaloolefin and ozone. The polymers obtained are substantially free of oxidizing linkages. The polyhalocarbon oxides and hydrolyzed products obtained therefrom are useful as intermediates for stabilized materials useful, for instance, as heat transfer media and lubricants, and for cured materials useful, for instance, in sealant systems and adhesive systems.
摘要翻译：公开了一种不需要使用光的生产多卤氧化物的方法。该方法包括将全卤代烯烃和臭氧引入反应区。获得的聚合物基本上不含氧化键。从其获得的多卤氧化物和水解产物可用作稳定材料的中间体，例如作为传热介质和润滑剂，以及用于例如在密封剂系统和粘合剂体系中有用的固化材料。

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