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    • 1. 发明授权
    • Systems and methods for preparing autologous fibrin glue
    • 制备自体纤维蛋白胶的系统和方法
    • US08491564B2
    • 2013-07-23
    • US12424317
    • 2009-04-15
    • Roberto BerettaNicholas A. Grippi
    • Roberto BerettaNicholas A. Grippi
    • A61B19/00
    • A61L24/106A61B17/00491A61B2017/00495A61C5/64A61J1/062A61J1/201A61J1/2013A61J1/2065A61J1/2086A61J1/2089A61L24/00B01D21/262B01D33/15
    • The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a separation medium and a low-density high-viscosity liquid. The separation medium is capable of separating red blood cells from plasma when the container contains blood and is centrifuged, and the primary container has a first pressure. The system further includes a sealed secondary container containing a calcium-coagulation activator. The secondary container has a second pressure that is less than the first pressure. The system also includes a transfer device having a cannula with a first end and a second end. The first and second ends are adapted to puncture the sealed primary and secondary containers in order to provide fluid communication between the first and second containers.
    • 本发明提供了一种用于制备适于再生生物体中的组织的自体固体纤维蛋白网的系统。 该系统包括含有分离介质和低密度高粘度液体的密封的初级容器。 当容器含有血液并离心时,分离介质能够将红细胞与血浆分离,并且主容器具有第一压力。 该系统还包括含有钙凝固活化剂的密封的次级容器。 次级容器具有小于第一压力的第二压力。 该系统还包括具有带有第一端和第二端的插管的转移装置。 第一和第二端适于刺穿密封的初级和次级容器,以便在第一和第二容器之间提供流体连通。