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1. 发明授权

US06183512B2 Flexible annuloplasty system 有权
标题翻译：弹性瓣环成形术系统
公开(公告)号：US06183512B2
公开(公告)日：2001-02-06
申请号：US09293214
申请日：1999-04-16
申请人： Myron Howanec, Jr. , Michael John Scott , Brian Eugene Brutcher , Jerry L. Jackman
发明人： Myron Howanec, Jr. , Michael John Scott , Brian Eugene Brutcher , Jerry L. Jackman
IPC分类号： A61F224
CPC分类号： A61F2/2451 , Y10S623/904
摘要： A design and method of implantation is disclosed for a flexible annuloplasty system for repairing a valve in a patient's heart. The annuloplasty system includes an elongate, flexible band with a needle attached to one end of the band and a fit adjuster attached to the other end of the band. The band is made of silicone and includes a plurality of fibers that are configured to prevent axial elongation of the band. In addition, the plurality of fibers ensure that a suture will catch on the fibers and prevent the suture from tearing out of the band.
摘要翻译：公开了一种用于修复患者心脏中的瓣膜的柔性瓣环成形术系统的植入设计和方法。瓣膜成形术系统包括细长的柔性带，其带有附接到带的一端的针和附接到带的另一端的配合调节器。该带由硅树脂制成并且包括被配置为防止带的轴向伸长的多个纤维。此外，多根纤维确保缝合线将捕获在纤维上并防止缝合线从带上撕裂。

2. 发明授权

US07008591B2 Supercritical fluid extraction process for tissue preparation 有权
公开(公告)号：US07008591B2
公开(公告)日：2006-03-07
申请号：US09981274
申请日：2001-10-17
申请人： Ralph Kafesjian , Myron Howanec, Jr.
发明人： Ralph Kafesjian , Myron Howanec, Jr.
IPC分类号： A16L11/00 , A16F2/76
CPC分类号： A61L27/3687 , A61L2/0011 , A61L2/0088 , A61L2/0094 , A61L27/3604 , Y10S623/915
摘要： The present invention provides methods for preparing tissue for incorporation into xenografts and bioprosthetic devices. The methods of the invention make use of supercritical fluids to remove infectious materials and chemical agents from tissues, as well as to permeate a tissue with a chemical agent (e.g. tanning, cross-linking, and bioactive agents).

3. 发明授权

US06964682B2 Heart valve holder that resist suture looping 有权
标题翻译：心脏瓣膜支架阻止缝合环
公开(公告)号：US06964682B2
公开(公告)日：2005-11-15
申请号：US09745386
申请日：2000-12-21
申请人： Diana Nguyen-Thien-Nhon , Myron Howanec, Jr. , Ralph Kafesjian , Delos M. Cosgrove , Robert Stobie , Hung Ly Lam
发明人： Diana Nguyen-Thien-Nhon , Myron Howanec, Jr. , Ralph Kafesjian , Delos M. Cosgrove , Robert Stobie , Hung Ly Lam
IPC分类号： A61F2/24 , A61F2/48
CPC分类号： A61F2/2427 , A61F2/2412
摘要： An improved holder, system and method for implanting a tissue-type prosthetic mitral heart valve that prevents suture looping and may also constrict the commissure posts of the valve. The holder may include two relatively movable plates, one of which attaches to the valve sewing on the inflow end of the valve ring and the other which attaches via sutures or similar expedient to the valve commissures on the outflow end. Separation of the plates places the sutures in tension and constricts the commissures. The sutures may be strands or filaments, or may be wider bands of flexible biocompatible material. If bands are used, they desirably cover the commissure post tips to further help prevent suture looping thereover. The flexible lengths of material extend directly between commissures of the valve, or may extending radially inward from each commissure to a central upstanding member. Desirably, a slide is created by the flexible lengths of material adjacent each commissure post, for example by crossing over suture filaments at or radially inward from the commissure posts. If an upstanding member is used, the lengths of suture extend axially beyond the commissure post tips to create a tent that wards off sutures that otherwise might loop around the tips during advancement of the valve along an array of pre-implanted sutures.
摘要翻译：改进的用于植入组织型假体二尖瓣心脏瓣膜的保持器，系统和方法，其防止缝合线环绕并且还可以约束瓣膜的连合柱。保持器可以包括两个相对可移动的板，其中一个连接到阀环的流入端上的阀缝合，另一个通过缝合线或类似的方式附接到流出端上的阀连接。板的分离使缝合线处于紧张状态并限制合缝。缝合线可以是股线或长丝，或者可以是更宽的柔性生物相容性材料带。如果使用条带，它们理想地覆盖连合后端，以进一步有助于防止缝合在其上。柔性长度的材料在阀的连合之间直接延伸，或者可以从每个连接处径向向内延伸到中心直立构件。期望地，通过邻近每个连合柱的柔性长度的材料产生滑块，例如通过在接合柱上或径向向内穿过缝合线。如果使用直立的构件，则缝合线的长度轴向延伸超过连合后端，以产生防止缝合线的帐篷，否则，可以沿着预先植入的缝合线阵列推进阀门周围的尖端。

4. 发明授权

US06503274B1 Method of implanting a flexible annuloplasty system 有权
标题翻译：植入柔性瓣膜成形术系统的方法
公开(公告)号：US06503274B1
公开(公告)日：2003-01-07
申请号：US09708895
申请日：2000-11-08
申请人： Myron Howanec, Jr. , Michael John Scott , Brian Eugene Brutcher , Jerry L. Jackman
发明人： Myron Howanec, Jr. , Michael John Scott , Brian Eugene Brutcher , Jerry L. Jackman
IPC分类号： A61F206
CPC分类号： A61F2/2451 , Y10S623/904
摘要： A design and method of implantation is disclosed for a flexible annuloplasty system for repairing a valve in a patient's heart. The annuloplasty system includes an elongate, flexible band with a needle attached to one end of the band and a fit adjuster attached to the other end of the band. The band is made of silicone and includes a plurality of fibers that are configured to prevent axial elongation of the band. In addition, the plurality of fibers ensure that a suture will catch on the fibers and prevent the suture from tearing out of the band.
摘要翻译：公开了一种用于修复患者心脏中的瓣膜的柔性瓣环成形术系统的植入设计和方法。瓣膜成形术系统包括细长的柔性带，其带有附接到带的一端的针和附接到带的另一端的配合调节器。该带由硅树脂制成并且包括被配置为防止带的轴向伸长的多个纤维。此外，多根纤维确保缝合线将捕获在纤维上并防止缝合线从带上撕裂。

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