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    • 7. 发明申请
    • Novel Plexin Polypeptide, Dna Encoding the Same and Use Thereof
    • 新型Plexin多肽,Dna编码相同,并使用它们
    • US20070212365A1
    • 2007-09-13
    • US10573262
    • 2004-10-28
    • Hisashi KogaOsamu OharaHaruhiko KosekiMitsuhiro OkadaAkiyoshi UemuraHiroki ArakawaMitsuhiro Tada
    • Hisashi KogaOsamu OharaHaruhiko KosekiMitsuhiro OkadaAkiyoshi UemuraHiroki ArakawaMitsuhiro Tada
    • A61K39/00G01N33/574C07H21/04C12P21/06C12N5/06C07K14/82
    • C07K14/705A61K38/00
    • The object of the invention is to provide novel DNA, a gene containing the DNA, novel polypeptide encoded by the DNA, a recombinant protein containing the polypeptide, or an antibody against the polypeptide, which is useful for development and screening of prophylactic, therapeutic and diagnostic drug for angiogenesis and conservation of functions in various organs, angiogenesis at the time of tumor and regeneration of various organs, proliferation, differentiation and preservation of function of the cells in various organs, aging, and dysfunction. Means to Solve the Problem A DNA comprising a base sequence encoding one of the following polypeptide (a) or (b): (a) a polypeptide comprising the full length or a part of an amino acid sequence which is the same or substantially the same as an amino acid sequence represented by SEQ ID NO:1, SEQ ID NO:15 or SEQ ID NO:18, and (b) a polypeptide comprising an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:1, SEQ ID NO:15 or SEQ ID NO:18 by deletion, substitution or addition of a part of the amino acids and having a biological activity substantially equivalent to the polypeptide (a).
    • 本发明的目的是提供新的DNA,含有DNA的基因,由DNA编码的新型多肽,含有多肽的重组蛋白或抗多肽的抗体,其可用于开发和筛选预防性治疗和 用于血管发生的诊断药物和各种器官功能的保存,肿瘤时的血管发生和各种器官的再生,增殖,分化和保存各种器官,衰老和功能障碍中的细胞的功能。 解决问题的方法包含编码以下多肽(a)或(b)之一的碱基序列的DNA:(a)包含相同或基本相同的氨基酸序列的全长或部分的多肽 作为由SEQ ID NO:1,SEQ ID NO:15或SEQ ID NO:18表示的氨基酸序列,和(b)包含源自SEQ ID NO:1所示氨基酸序列的氨基酸序列的多肽, SEQ ID NO:15或SEQ ID NO:18,通过缺失,取代或添加一部分氨基酸并且具有与多肽(a)基本相同的生物活性。
    • 8. 发明授权
    • Game token dispenser
    • 游戏令牌分配器
    • US5366110A
    • 1994-11-22
    • US915718
    • 1992-07-28
    • Takatoshi TakemotoYoshihide KuriharaKoshiro NakaiSakuji YaegashiHiroyasu ObaraMitsuhiro Tada
    • Takatoshi TakemotoYoshihide KuriharaKoshiro NakaiSakuji YaegashiHiroyasu ObaraMitsuhiro Tada
    • G07D1/02G07F11/00
    • G07D1/02
    • A game token dispenser is equipped with a token hopper for dispensing, to a token receiving port, a predetermined number of tokens supplied from a token reservoir. The token hopper is divided into a sequentially operating preliminary hopper and a dispensing hopper. The preliminary hopper has a sensor for detecting whether or not there are any tokens received from the reservoir, and a conveying mechanism for conveying the tokens forwardly. The dispensing hopper has a sensor for detecting whether or not there are any tokens received from the preliminary hopper. A discharging mechanism is provided for discharging the tokens one by one to the token receiving port. The dispenser preferably includes a display, on a front surface of a housing, for displaying whether or not it is possible to dispense the tokens and the number of the tokens dispensed. The dispenser preferably also includes a counting sensor disposed in a dispensing path between the dispensing hopper and the token receiving port for counting the tokens dispensed. The dispenser may also include a sensor located adjacent to the token receiving port for detecting whether the tokens overlap one another. This latter sensor may also be capable of sensing whether or not the tokens are stored in the token receiving port for a predetermined time. When the predetermined number of tokens, as counted by the counting sensor, are dispensed, upon detection that the tokens are stored in the token receiving port the dispenser displays an information message such as "now dispensing", and any paper currency can be prohibited from being inserted into the dispenser.
    • PCT No.PCT / JP91 / 01654 Sec。 371日期:1992年7月28日 102(e)日期1992年7月28日PCT 1991年11月19日PCT PCT。 公开号WO92 / 09346 日期为1992年11月6日。游戏令牌分配器配备有令牌料斗,用于向令牌接收端口分配从令牌储存器提供的预定数量的令牌。 令牌料斗被分为顺序操作的预料斗和分配料斗。 预备料斗具有用于检测是否存在从储存器接收到的令牌的传感器,以及用于向前传送令牌的输送机构。 分配料斗具有用于检测是否存在从预备料斗接收的任何标记的传感器。 提供排放机构,用于将令牌逐个排出到令牌接收端口。 分配器优选地包括在壳体的前表面上的显示器,用于显示是否可以分配令牌和分配的令牌的数量。 分配器优选地还包括设置在分配料斗和令牌接收端口之间的分配路径中的计数传感器,用于计数分配的令牌。 分配器还可以包括位于令牌接收端口附近的传感器,用于检测令牌是否彼此重叠。 后一种传感器还可能能够感测令牌是否存储在令牌接收端口中一段预定的时间。 当通过计数传感器计数的预定数量的令牌被分配时,在检测到令牌被存储在令牌接收端口中时,分配器显示诸如“现在分配”的信息消息,并且可以禁止任何纸币 插入分配器。
    • 9. 发明申请
    • GAME SYSTEM AND GAME MACHINE
    • 游戏系统和游戏机
    • US20090137297A1
    • 2009-05-28
    • US12090263
    • 2006-10-25
    • Shigehito MukasaMitsuhiro TadaDaisuke Yoro
    • Shigehito MukasaMitsuhiro TadaDaisuke Yoro
    • A63F9/00
    • A63F9/00A63F9/0096A63F2250/027
    • A present invention provides a game system in which a battle game according to a game skill of a player is realized in a target hitting game. In the game system, the target hitting game is played with a game machine. The game system includes a criterial strength determination device for determining criterial strength of the player, win-loss influence information control device for changing the information having the influence on win or loss of the opponent based on measurement strength measured for the hit in the game, the win-loss influence information control device changing the information having the influence on win or loss of the player based on the criterial strength when the target is not hit, and a win-loss judgment device for judging the win or loss of the game based on the information having the influence on win or loss of the player and the opponent.
    • 本发明提供一种游戏系统,其中,在目标打击游戏中实现根据玩家的游戏技能的战斗游戏。 在游戏系统中,用游戏机玩目标打击游戏。 游戏系统包括:用于根据游戏中的命中测量的测量强度来确定玩家的标准强度的标准强度确定装置,用于改变对对手的失败影响的信息的胜利影响信息控制装置; 所述失败影响信息控制装置根据所述目标未被击中的标准强度来改变对所述玩家的胜负的影响的信息,以及用于判断所述游戏的胜负失败的胜利判断装置 对玩家和对手的胜利或损失有影响的信息。