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1. 发明申请

US20150182151A1 Optical Probes for Non-Invasive Analyte Measurements 审中-公开
标题翻译：用于非侵入性分析物测量的光学探针
公开(公告)号：US20150182151A1
公开(公告)日：2015-07-02
申请号：US14638834
申请日：2015-03-04
申请人： Trent Ridder , Ben Ver Steeg , Mike Mills
发明人： Trent Ridder , Ben Ver Steeg , Mike Mills
IPC分类号： A61B5/1455 , A61B5/145
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B2562/0233 , A61B2562/0238 , A61B2562/046 , A61B2562/12 , G01N21/474 , G01N21/4795 , G01N21/49 , G01N2021/4745 , G01N2201/0846 , Y10T29/49764
摘要： An optical probe for non-invasively measuring an analyte property in a biological sample of a subject, comprises a plurality of illumination fibers that deliver source light from an optical probe input to a sample interface, a plurality of collection fibers that deliver light returned from the sample interface to an optical probe output, and wherein the illumination and collection fibers are oriented substantially perpendicular to the sample interface and the illumination and collection fibers are stacked in a plurality of linear rows to provide a stack of fibers arranged in a rectangular pattern. The optical probe is amenable to manufacturing on a scale consistent with a commercial product.
摘要翻译：一种用于非侵入性测量受试者的生物样品中的分析物质的光学探针包括将源光从光学探针输入传送到样品界面的多个照明纤维，多个收集纤维，其将从样品接口连接到光学探针输出，并且其中照明和收集光纤基本上垂直于样品界面定向，并且照明和收集光纤以多个线性行堆叠以提供以矩形图案布置的纤维堆叠。光学探针适合于与商业产品一致的尺寸制造。

2. 发明授权

US4786037A Arrangement for a spring suspension system 失效
标题翻译：弹簧悬挂系统的布置
公开(公告)号：US4786037A
公开(公告)日：1988-11-22
申请号：US916677
申请日：1986-10-15
申请人： Mike Mills
发明人： Mike Mills
IPC分类号： B60G15/06 , B60G17/02 , B62K25/08 , F16F9/18 , F16F9/36 , F16F5/00
CPC分类号： F16F9/366 , B60G15/061 , F16F9/185
摘要： Included in a spring suspension system is a main spring (1) for taking up a load or for supporting a mass. The spring is arranged on a cylinder (4) which contains a piston (5). The piston or the area of the piston rod operates via hydraulic oil against the effect of a spring function, the purpose of which is to ensure that the fluid is under pressure at all times. A moving device (7) interacts both with the fluid an with the aforementioned main spring (1), which for this purpose is so arranged as to provide the double function of serving both as a load/mass supporting spring and as a compression spring.
摘要翻译： PCT No.PCT / SE85 / 00534 Sec。 371日期1986年10月15日第 102（e）日期1986年10月15日PCT提交1985年12月19日PCT公布。公开号WO86 / 04125 日期1986年7月17日。包括在弹簧悬挂系统中的是用于承载或用于支撑质量的主弹簧（1）。弹簧布置在包含活塞（5）的气缸（4）上。活塞或活塞杆的区域通过液压油操作，以抵抗弹簧功能的作用，其目的是确保流体始终处于压力下。移动装置（7）与流体a与上述主弹簧（1）相互作用，为此，其设置为提供作为负载/质量支撑弹簧和压缩弹簧的双重功能。

3. 发明授权

US08174394B2 System for noninvasive determination of analytes in tissue 失效
标题翻译：非侵入性测定组织中分析物的系统
公开(公告)号：US08174394B2
公开(公告)日：2012-05-08
申请号：US12562050
申请日：2009-09-17
申请人： Trent Ridder , Ben ver Steeg , Mike Mills , Bentley Laaksonen , James McNally , John Maynard , Russell Abbink
发明人： Trent Ridder , Ben ver Steeg , Mike Mills , Bentley Laaksonen , James McNally , John Maynard , Russell Abbink
IPC分类号： G08B13/14 , A61B5/1455
CPC分类号： A61B5/4845 , A61B5/0075 , A61B5/0088 , A61B5/117 , A61B5/14546 , A61B5/1455 , A61B5/1495 , A61B5/6826 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0229 , G01J3/0291 , G01J3/14 , G01J2003/1286 , G01N21/274 , G01N21/359 , G01N21/474 , G01N2201/129
摘要： An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments.
摘要翻译：一种用于通过定量红外光谱法非临床确定人体组织的分析物质的临床相关水平的精确度和准确度的装置和方法。该系统包括优化的子系统，以应对组织光谱的复杂性，高信噪比和光度精度要求，组织采样误差，校准维护问题和校准转移问题。子系统可以包括照明/调制子系统，组织采样子系统，数据采集子系统，计算子系统和校准子系统。本发明可以提供来自相同光谱信息的分析物质性质确定和鉴别确定或验证，使得未经授权的使用或误导结果比使用单独的分析物和身份确定的系统更不可能。本发明可用于控制和监视访问受控环境的个人。

4. 发明授权

US07848605B2 Method of making optical probes for non-invasive analyte measurements 有权
标题翻译：制造用于非侵入性分析物测量的光学探针的方法
公开(公告)号：US07848605B2
公开(公告)日：2010-12-07
申请号：US12185224
申请日：2008-08-04
申请人： Trent Ridder , Ben ver Steeg , Mike Mills
发明人： Trent Ridder , Ben ver Steeg , Mike Mills
IPC分类号： G02B6/44
CPC分类号： G01N21/49 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B2562/0233 , A61B2562/046 , A61B2562/12 , G01N21/474 , G01N21/4795 , G01N2021/4745 , G01N2201/0846 , Y10S385/901
摘要： An optical probe for non-invasively measuring an analyte property in a biological sample of a subject, comprises a plurality of illumination fibers that deliver source light from an optical probe input to a sample interface, a plurality of collection fibers that deliver light returned from the sample interface to an optical probe output, and wherein the illumination and collection fibers are oriented substantially perpendicular to the sample interface and the illumination and collection fibers are stacked in a plurality of linear rows to provide a stack of fibers arranged in a rectangular pattern. The optical probe is amenable to manufacturing on a scale consistent with a commercial product. Methods of making such probes are described.
摘要翻译：一种用于非侵入性测量受试者的生物样品中的分析物质的光学探针包括将源光从光学探针输入传送到样品界面的多个照明纤维，多个收集纤维，其将从样品接口连接到光学探针输出，并且其中照明和收集光纤基本上垂直于样品界面定向，并且照明和收集光纤以多个线性行堆叠以提供以矩形图案布置的纤维堆叠。光学探针适合于与商业产品一致的尺寸制造。描述制造这种探针的方法。

5. 发明申请

US20110282167A1 SYSTEM FOR NONINVASIVE DETERMINATION OF ALCOHOL IN TISSUE 审中-公开
标题翻译：用于组织中非酒精性酒精测定的系统
公开(公告)号：US20110282167A1
公开(公告)日：2011-11-17
申请号：US13145927
申请日：2010-01-23
申请人： Trent Ridder , Ben Ver Steeg , Mike Mills , Bentley Laaksonen
发明人： Trent Ridder , Ben Ver Steeg , Mike Mills , Bentley Laaksonen
IPC分类号： A61B5/1455
CPC分类号： A61B5/4845 , A61B5/0075 , A61B5/0088 , A61B5/14546 , A61B5/1455 , A61B5/1495 , A61B5/6826 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0229 , G01J3/0291 , G01J3/14 , G01J2003/1286 , G01N21/274 , G01N21/359 , G01N21/474 , G01N2201/129
摘要： An apparatus and method for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal- to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems include an illumination/modulation subsystem, a tissue sampling subsystem, a calibration maintenance subsystem, an FTIR spectrometer subsystem, a data acquisition subsystem, and a computing subsystem.
摘要翻译：一种用于通过定量红外光谱法非侵入性地确定人体组织属性的装置和方法，其临床相关的精度和准确性水平。该系统包括针对组织谱的复杂性，高信噪比和光度精度要求进行优化的子系统，组织抽样误差，校准维护问题和校准传递问题。子系统包括照明/调制子系统，组织采样子系统，校准维护子系统，FTIR光谱仪子系统，数据采集子系统和计算子系统。

6. 发明申请

US20110178420A1 METHODS AND APPARATUSES FOR IMPROVING BREATH ALCOHOL TESTING 审中-公开
标题翻译：用于改善呼吸酒精测试的方法和装置
公开(公告)号：US20110178420A1
公开(公告)日：2011-07-21
申请号：US13008000
申请日：2011-01-17
申请人： Trent Ridder , Bill Kardeen , Bentley Laaksonen , Ben Ver Steeg , James McNally , Mike Mills
发明人： Trent Ridder , Bill Kardeen , Bentley Laaksonen , Ben Ver Steeg , James McNally , Mike Mills
IPC分类号： A61B5/08
CPC分类号： A61B5/1455 , A61B5/14546 , A61B5/4845 , G01N21/314 , G01N21/3504 , G01N21/359 , G01N21/65 , G01N33/4972 , G01N2201/129
摘要： Some embodiments of the present invention provide methods and apparatuses for improving the performance and utility of breath alcohol measurements through the use of multivariate spectroscopy. In some embodiments, the spectroscopic breath measurement can be combined with multivariate spectroscopic tissue alcohol and/or tissue biometric measurements in order to overcome the limitations encountered by existing breath alcohol measurement devices.
摘要翻译：本发明的一些实施例提供了通过使用多变量光谱来改善呼吸酒精测量的性能和效用的方法和装置。在一些实施例中，光谱呼吸测量可以与多变量光谱组织醇和/或组织生物测定结合，以克服现有呼吸酒精测量装置遇到的限制。

7. 发明申请

US20080319286A1 Optical Probes for Non-Invasive Analyte Measurements 审中-公开
标题翻译：用于非侵入性分析物测量的光学探针
公开(公告)号：US20080319286A1
公开(公告)日：2008-12-25
申请号：US12185217
申请日：2008-08-04
申请人： Trent Ridder , Ben ver Steeg , Mike Mills
发明人： Trent Ridder , Ben ver Steeg , Mike Mills
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B2562/0233 , A61B2562/0238 , A61B2562/046 , A61B2562/12 , G01N21/474 , G01N21/4795 , G01N21/49 , G01N2021/4745 , G01N2201/0846 , Y10T29/49764
摘要： An optical probe for non-invasively measuring an analyte property in a biological sample of a subject, comprises a plurality of illumination fibers that deliver source light from an optical probe input to a sample interface, a plurality of collection fibers that deliver light returned from the sample interface to an optical probe output, and wherein the illumination and collection fibers are oriented substantially perpendicular to the sample interface and the illumination and collection fibers are stacked in a plurality of linear rows to provide a stack of fibers arranged in a rectangular pattern. The optical probe is amenable to manufacturing on a scale consistent with a commercial product.
摘要翻译：一种用于非侵入性测量受试者的生物样品中的分析物质的光学探针包括将源光从光学探针输入传送到样品界面的多个照明纤维，多个收集纤维，其将从样品接口连接到光学探针输出，并且其中照明和收集光纤基本上垂直于样品界面定向，并且照明和收集光纤以多个线性行堆叠以提供以矩形图案布置的纤维堆叠。光学探针适合于与商业产品一致的尺寸制造。

8. 发明申请

US20050043600A1 Low-noise optical probes for reducing ambient noise 失效
标题翻译：用于降低环境噪声的低噪声光学探头
公开(公告)号：US20050043600A1
公开(公告)日：2005-02-24
申请号：US10957843
申请日：2004-10-04
申请人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David Tobler , Thomas Gerhardt , Eugene Mason , Mike Mills
发明人： Mohamed Diab , Esmaiel Kiani-Azarbayjany , David Tobler , Thomas Gerhardt , Eugene Mason , Mike Mills
IPC分类号： A61B5/022 , A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/145 , A61B5/1455 , G01N21/17 , G01N21/59 , H05K1/18
CPC分类号： A61B5/14552 , A61B5/02427 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B2562/08 , A61B2562/12 , H05K1/189
摘要： An optical probe, which is particularly suited to reduce noise in measurements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip, measures characteristics of the material. A neonatal and adult disposable embodiment of the probe include adhesive coated surfaces to securely affix the probe onto the patient. In addition, the surface of the probe is specially constructed to reduce the effect of ambient noise.
摘要翻译：光学探头特别适用于减少在容易压缩的材料（例如手指，脚趾，额头，耳垂或唇部）上进行的测量中的噪音，测量材料的特性。探针的新生儿和成人一次性实施例包括粘合剂涂覆的表面以牢固地将探针附接到患者身上。此外，探头的表面是特别构造的，以减少环境噪声的影响。

9. 发明申请

US20150208983A9 SYSTEM FOR NONINVASIVE DETERMINATION OF ALCOHOL IN TISSUE 审中-公开
标题翻译：用于组织中非酒精性酒精测定的系统
公开(公告)号：US20150208983A9
公开(公告)日：2015-07-30
申请号：US13145927
申请日：2010-01-23
申请人： Trent Ridder , Ben Ver Steeg , Mike Mills , Bentley Laaksonen
发明人： Trent Ridder , Ben Ver Steeg , Mike Mills , Bentley Laaksonen
IPC分类号： A61B5/1455 , A61B5/145
CPC分类号： A61B5/4845 , A61B5/0075 , A61B5/0088 , A61B5/117 , A61B5/14546 , A61B5/1455 , A61B5/1495 , A61B5/6826 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0229 , G01J3/0291 , G01J3/14 , G01J2003/1286 , G01N21/274 , G01N21/359 , G01N21/474 , G01N2201/129
摘要： An apparatus and method for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal- to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems include an illumination/modulation subsystem, a tissue sampling subsystem, a calibration maintenance subsystem, an FTIR spectrometer subsystem, a data acquisition subsystem, and a computing subsystem.
摘要翻译：一种用于通过定量红外光谱法非侵入性地确定人体组织属性的装置和方法，其临床相关的精度和准确性水平。该系统包括针对组织谱的复杂性，高信噪比和光度精度要求进行优化的子系统，组织抽样误差，校准维护问题和校准传递问题。子系统包括照明/调制子系统，组织采样子系统，校准维护子系统，FTIR光谱仪子系统，数据采集子系统和计算子系统。

10. 发明申请

US20100010325A1 System for Noninvasive Determination of Analytes in Tissue 失效
标题翻译：无创测定组织中分析物的系统
公开(公告)号：US20100010325A1
公开(公告)日：2010-01-14
申请号：US12562050
申请日：2009-09-17
申请人： Trent Ridder , Ben ver Steeg , James McNally , John Maynard , Russell Abbink , Mike Mills , Bentley Laaksonen
发明人： Trent Ridder , Ben ver Steeg , James McNally , John Maynard , Russell Abbink , Mike Mills , Bentley Laaksonen
IPC分类号： A61B5/1455 , A61B5/117 , G06F7/04
CPC分类号： A61B5/4845 , A61B5/0075 , A61B5/0088 , A61B5/117 , A61B5/14546 , A61B5/1455 , A61B5/1495 , A61B5/6826 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0229 , G01J3/0291 , G01J3/14 , G01J2003/1286 , G01N21/274 , G01N21/359 , G01N21/474 , G01N2201/129
摘要： An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments.
摘要翻译：一种用于通过定量红外光谱法非临床确定人体组织的分析物质的临床相关水平的精确度和准确度的装置和方法。该系统包括优化的子系统，以应对组织光谱的复杂性，高信噪比和光度精度要求，组织采样误差，校准维护问题和校准转移问题。子系统可以包括照明/调制子系统，组织采样子系统，数据采集子系统，计算子系统和校准子系统。本发明可以提供来自相同光谱信息的分析物质性质确定和鉴别确定或验证，使得未经授权的使用或误导结果比使用单独的分析物和身份确定的系统更不可能。本发明可用于控制和监视访问受控环境的个人。

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