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1. 发明授权

US07800479B2 Semiconductor device having a trim cut and method of evaluating laser trimming thereof 有权
标题翻译：具有修剪切割的半导体器件及其激光修整的评估方法
公开(公告)号：US07800479B2
公开(公告)日：2010-09-21
申请号：US12292352
申请日：2008-11-18
申请人： Michio Yamashita
发明人： Michio Yamashita
IPC分类号： H01C10/00
CPC分类号： H01C17/242 , H01L28/20 , Y10T29/49082 , Y10T29/49099
摘要： A method of evaluating laser trimming of a semiconductor device having a thin film resistor is disclosed. The method includes the steps of providing the thin film resistor and laser trimming the thin film resistor by creating a first trim cut. The first trim cut bisects the thin film resistor such that the thin film resistor is divided into a first portion and a second portion. Also, the method involves measuring the insulation resistance of the thin film resistor. In addition, the method involves evaluating the trim cut based on the measured insulation resistance.
摘要翻译：公开了一种评估具有薄膜电阻器的半导体器件的激光微调的方法。该方法包括以下步骤：通过创建第一切割来提供薄膜电阻器和激光微调薄膜电阻器。第一修剪片将薄膜电阻器平分，使得薄膜电阻器被分成第一部分和第二部分。此外，该方法包括测量薄膜电阻器的绝缘电阻。此外，该方法包括基于所测量的绝缘电阻来评估修剪切割。

2. 发明申请

US20090079536A1 Semiconductor device having a trim cut and method of evaluating laser trimming thereof 有权
标题翻译：具有修剪切割的半导体器件及其激光修整的评估方法
公开(公告)号：US20090079536A1
公开(公告)日：2009-03-26
申请号：US12292352
申请日：2008-11-18
申请人： Michio Yamashita
发明人： Michio Yamashita
IPC分类号： H01C10/00
CPC分类号： H01C17/242 , H01L28/20 , Y10T29/49082 , Y10T29/49099
摘要： A method of evaluating laser trimming of a semiconductor device having a thin film resistor is disclosed. The method includes the steps of providing the thin film resistor and laser trimming the thin film resistor by creating a first trim cut. The first trim cut bisects the thin film resistor such that the thin film resistor is divided into a first portion and a second portion. Also, the method involves measuring the insulation resistance of the thin film resistor. In addition, the method involves evaluating the trim cut based on the measured insulation resistance.
摘要翻译：公开了一种评估具有薄膜电阻器的半导体器件的激光微调的方法。该方法包括以下步骤：通过创建第一切割来提供薄膜电阻器和激光微调薄膜电阻器。第一修剪片将薄膜电阻器平分，使得薄膜电阻器被分成第一部分和第二部分。此外，该方法包括测量薄膜电阻器的绝缘电阻。此外，该方法包括基于所测量的绝缘电阻来评估修剪切割。

3. 发明授权

US06825003B2 Cyclic lipopeptide acylase 失效
标题翻译：循环脂肽酰基转移酶
公开(公告)号：US06825003B2
公开(公告)日：2004-11-30
申请号：US10050150
申请日：2002-01-18
申请人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
发明人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
IPC分类号： C12N120
CPC分类号： C12P21/02 , A61K38/00 , C07K7/56 , C12N9/80
摘要： The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase. [wherein R1 is acyl; R2 is hydroxy or acyloxy; R3 is hydrogen or hydroxy; R4 is hydrogen or hydroxy; R5 is hydrogen or hydroxysulfonyloxy; and R6 is hydrogen or carbamoyl]
摘要翻译：本发明提供一种环状脂肽酰基转移酶，其可以有效地使酰基侧链环化脂肽化合物脱酰化，特别是FR901379由下列通式[I]表示的物质或其类似物，以及环肽化合物的制备方法包括使用所述酰基转移酶[其中R 1是酰基; R 2是羟基或酰氧基; R 3是氢或羟基; R 4是氢或羟基; R 5是氢或羟基磺酰氧基和R 6是氢或氨基甲酰基]

4. 发明授权

US06576135B1 Method for separating lactone-containing high-molecular weight compounds 有权
公开(公告)号：US06576135B1
公开(公告)日：2003-06-10
申请号：US10069964
申请日：2002-03-08
申请人： Tomoji Higaki , Takashi Yoshiyasu , Norihiro Hashimoto , Keiji Honda , Hiroshi Hatanaka , Michio Yamashita
发明人： Tomoji Higaki , Takashi Yoshiyasu , Norihiro Hashimoto , Keiji Honda , Hiroshi Hatanaka , Michio Yamashita
IPC分类号： B01D1508
CPC分类号： C07D498/18
摘要： A method for separating a lactone-containing high-molecular weight compound comprising subjecting a mixture of a lactone-containing high-molecular weight compound having, as its side-chain, at least one of a lower alkenyl group and a lower alkoxy group and its analogous compound(s) to either one or both steps in any order of a step (A) for adsorbing the mixture to a nonionic adsorption resin and eluting with an aqueous solvent containing silver ions, and a step (B) for adsorbing the mixture to a basic active alumina and eluting with an organic solvent to separate each of the compounds.

5. 发明授权

US06492513B1 Method for separating analogous organic compounds 有权
标题翻译：分离类似有机化合物的方法
公开(公告)号：US06492513B1
公开(公告)日：2002-12-10
申请号：US09926611
申请日：2001-11-26
申请人： Yutaka Nishihara , Keiji Honda , Koji Mukai , Norihiro Hashimoto , Hiroshi Hatanaka , Michio Yamashita
发明人： Yutaka Nishihara , Keiji Honda , Koji Mukai , Norihiro Hashimoto , Hiroshi Hatanaka , Michio Yamashita
IPC分类号： C07D49816
CPC分类号： C07D498/18 , B01D15/185 , B01D2215/023 , B01J39/05 , B01J39/20 , B01J39/26
摘要： The present invention relates to a method for separating a lactone-containing high-molecular weight compound having an alkyl group as its side chain from a lactone-containing high-molecular weight compound having an alkenyl group as its side chain by using a sulfonic acid group-containing cation exchange resin pretreated with silver ions.
摘要翻译：本发明涉及一种通过使用磺酸基从具有烯基作为侧链的含内酯的高分子量化合物分离具有烷基作为侧链的含内酯的高分子量化合物的方法含有银离子预处理的阳离子交换树脂。

6. 发明授权

US06423530B1 Process for preparing FR900482 and compounds analogous thereto 失效
标题翻译：制备FR900482及其类似物的方法
公开(公告)号：US06423530B1
公开(公告)日：2002-07-23
申请号：US09705898
申请日：2000-11-06
申请人： Masaru Tsuboi , Shiho Shimizu , Michio Yamashita , Yasuhisa Tsurumi , Seiji Hashimoto
发明人： Masaru Tsuboi , Shiho Shimizu , Michio Yamashita , Yasuhisa Tsurumi , Seiji Hashimoto
IPC分类号： C12N114
CPC分类号： C12P17/188 , Y10S435/929
摘要： A process for producing a compound of the general formula (I): (wherein R1 represents hydrogen, a lower alkanoyl group or a lower alkyl group; R2 and R3 each represents hydrogen or a lower alkanoyl group) characterized in that a compound of the general formula (II): (wherein R1, R2 and R3 are respectively as defined above) is reacted with a culture of a strain of microorganism belonging to the genus Fusarium or its cells harvested by filtering the broth.
摘要翻译：一种制备通式（I）的化合物的方法（其中R 1表示氢，低级烷酰基或低级烷基; R 2和R 3各自表示氢或低级烷酰基），其特征在于通式式（II）:(其中R1，R2和R3分别如上定义）与属于镰刀菌属的微生物菌株或通过过滤肉汤收获的细胞的培养物反应。

7. 发明授权

US06372474B1 Cyclic lipopeptide acylase 失效
标题翻译：循环脂肽酰基转移酶
公开(公告)号：US06372474B1
公开(公告)日：2002-04-16
申请号：US09659335
申请日：2000-09-12
申请人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
发明人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
IPC分类号： C12N950
CPC分类号： C12P21/02 , A61K38/00 , C07K7/56 , C12N9/80
摘要： The present invention provides a cyclic lipopeptide acrylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for production of a cyclic peptide compound which comprises the use of said acylase. [wherein R1 is acyl; R2 is hydroxy or acyloxy; R3 is hydrogen or hydroxy; R4 is hydrogen or hydroxy; R5 is hydrogen or hydroxysulfonyloxy; and R6 is hydrogen or carbamoyl]
摘要翻译：本发明提供一种环状脂肽丙烯酸酯，其可以有效地脱酰基环状脂肽化合物的酰基侧链，特别是由以下通式[I]表示的FR901379物质或其类似物，以及环肽化合物的制备方法包括使用所述酰基转移酶[其中R1是酰基; R2是羟基或酰氧基; R3是氢或羟基; R4是氢或羟基; R5是氢或羟基磺酰氧基; 和R6是氢或氨基甲酰基]

8. 发明授权

US06207434B1 Process for the deacylation of cyclic lipopeptides 有权
标题翻译：环状脂肽脱酰的方法
公开(公告)号：US06207434B1
公开(公告)日：2001-03-27
申请号：US09142045
申请日：1998-09-03
申请人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
发明人： Satoshi Ueda , Miho Tanaka , Masami Ezaki , Kazutoshi Sakamoto , Seiji Hashimoto , Nobutaka Oohata , Masaru Tsuboi , Michio Yamashita
IPC分类号： C12N914
CPC分类号： C12R1/465 , C07K7/56 , C12N9/80
摘要： There is provided a cyclic lipopeptide acylase which is capable of deacylating the acyl side chain of a cyclic lipopeptide compound, e.g. Substance FR901379 or its analog, of the general formula [I] with effectiveness as well a method of producing a cyclic peptide compound which comprises using the acylase.
摘要翻译：提供了能够使环状脂肽化合物的酰基侧链脱酰化的环状脂肽酰基酶。物质FR901379或其具有通式[I]的类似物，其有效性以及包含使用酰基转移酶的环肽化合物的制备方法。

9. 发明授权

US5446022A WF11243 substance 失效
标题翻译： WF11243物质
公开(公告)号：US5446022A
公开(公告)日：1995-08-29
申请号：US140074
申请日：1993-11-04
申请人： Akihiko Fujie , Shigehiro Takase , Michio Yamashita , Tomoko Sato , Seiji Hashimoto , Masakuni Okuhara
发明人： Akihiko Fujie , Shigehiro Takase , Michio Yamashita , Tomoko Sato , Seiji Hashimoto , Masakuni Okuhara
IPC分类号： A61K38/00 , C07K7/08 , C12P21/04 , C07K11/02 , A61K38/12 , C12N1/14 , C12P21/02
CPC分类号： C07K7/08 , A61K38/00 , Y10S435/911
摘要： The present invention relates to a novel polypeptide having the following presumed structure: ##STR1## and the compound has both excellent fungicidal and protozoicidal effects.
摘要翻译： PCT No.PCT / JP92 / 00586 Sec。 371日期：1993年11月4日 102（e）日期1993年11月4日PCT提交1992年5月8日PCT公布。 WO92 / 19648 PCT出版物本发明涉及具有以下推定结构的新型多肽：t杀真菌剂和原生动物作用。

10. 发明授权

US4768363A Method of levelling two-layered clad metal sheet 失效
标题翻译：两层复合金属板的整平方法
公开(公告)号：US4768363A
公开(公告)日：1988-09-06
申请号：US887033
申请日：1986-07-02
申请人： Michio Yamashita , Hiroshi Yoshida , Toru Sasaki , Hideo Abe , Tsuneo Nagamine , Norio Takashima , Hideki Watanabe , Shuji Watanabe
发明人： Michio Yamashita , Hiroshi Yoshida , Toru Sasaki , Hideo Abe , Tsuneo Nagamine , Norio Takashima , Hideki Watanabe , Shuji Watanabe
IPC分类号： B21B1/38 , B21B37/44 , B21D1/02 , C21D1/00 , B21D37/16 , B21D3/02
CPC分类号： B21D1/02 , B21B37/44 , C21D1/00 , B21B2001/383
摘要： A method for preventing the camber of a two-layered clad metal sheet having a base layer and a covering layer of different metals which exhibit different amounts of thermal contraction. The method comprises developing a temperature difference .DELTA. T expressed by the following formula between the base layer and the covering layer during a hot levelling, by providing a greater cooling effect before or during levelling to the layer which exhibits the greater thermal contraction than to the layer which exhibits the smaller thermal contraction:.DELTA.T=f (.DELTA..alpha., .alpha., a, To)where,.DELTA..alpha.: the difference in thermal expansion coefficient between both metalsa: the clad ratio (ratio of covering layer thickness to total sheet thickness)To: hot leveller inlet temperature (.degree.C.).alpha.: mean thermal expansion coefficient of both metals.Since the layer which exhibits a greater thermal contraction is forcibly cooled before or during a hot levelling adequately and by a required amount, the clad metal sheet does not exhibit any substantial camber after cooled down to the room temperature.
摘要翻译： PCT No.PCT / JP85 / 00658 Sec。 371日期：1986年7月2日 102（e）日期1986年7月2日PCT提交1985年11月28日PCT公布。公开号WO86 / 03435 日期：1986年6月19日。一种防止具有不同金属的基底层和覆盖层的两层复合金属片的弯度的方法，其具有不同的热收缩量。该方法包括在热平整过程中在基底层和覆盖层之间通过下列公式表示的温差DELTA T，通过在与层之间呈现更大的热收缩的层的平整之前或期间提供更大的冷却效果其表现出较小的热收缩：DELTA T = f（DELTAα，α，a，To）其中，ΔTAα：两种金属之间的热膨胀系数之差a：包层比（覆盖层厚度与总板厚的比率）To：热矫平机入口温度（℃）α：两种金属的平均热膨胀系数。由于表现出较大的热收缩的层在热调平之前或期间被充分地强度冷却并且所需的量，所以在冷却至室温后，复合金属板不会显示任何实质的弧度。

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