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1. 发明公开

US20240277469A1 Methods and Devices for Treating Tricuspid Valve Disease 审中-公开
公开(公告)号：US20240277469A1
公开(公告)日：2024-08-22
申请号：US18583369
申请日：2024-02-21
申请人： Vaikom S. Mahadevan , Michael J. Horzewski
发明人： Vaikom S. Mahadevan , Michael J. Horzewski
IPC分类号： A61F2/24 , A61F2/06
CPC分类号： A61F2/2418 , A61F2/06 , A61F2/2436 , A61F2220/0008
摘要： Systems and methods for treatment of tricuspid valve disease. The systems and methods can anchor a supplemental valve apparatus in the vena cavae and provide a competent valve positioned in the right atrium or in or through the tricuspid annulus without requiring an anchor in the tricuspid annulus. The supplemental valve apparatus can include a supplemental valve coupled to at least one supplemental valve structure, which can extend into at least one of the inferior vena cava or superior vena cava with the supplemental valve positioned in or adjacent the right atrium. The valve apparatus can be delivered percutaneously by a delivery system, which can include the supplement valve apparatus positioned between an inner and outer shaft that can be retracted to deploy the supplemental valve apparatus in or adjacent the right atrium. Methods of delivery and treating a tricuspid valve by a supplement valve apparatus are also described herein.

2. 发明申请

US20100022875A1 Systems and methods for monitoring and enabling use of a medical instrument 审中-公开
标题翻译：用于监测和使用医疗仪器的系统和方法
公开(公告)号：US20100022875A1
公开(公告)日：2010-01-28
申请号：US12586927
申请日：2009-09-30
申请人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
发明人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
IPC分类号： A61B8/00
CPC分类号： A61N7/00 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N2007/0073
摘要： Systems and methods monitor and enable the use of a medical instrument that is configured to be operated in a prescribed manner. The systems and methods employ a use register sized and configured to be carried by the medical instrument, which comprises a memory field for recording a start date and time at an instance of first operation of the medical instrument. The systems and methods also employ a use monitoring controller, which is adapted and configured to be coupled to the use register. The use monitoring controller includes a start validation function that compares the start date and time to a present real date and time and provides a start validation output based upon the comparison. The use monitoring controller also includes an enablement function that enables operation of the medical instrument only if the start validation output meets prescribed criteria.
摘要翻译：系统和方法监视和使用被配置为以规定的方式操作的医疗器械的使用。所述系统和方法采用由医疗器械承载的大小和构造的使用寄存器，其包括用于在医疗器械的第一次操作的情况下记录开始日期和时间的存储区域。系统和方法还采用使用监视控制器，其被适配和配置为耦合到使用寄存器。使用监视控制器包括启动验证功能，其将开始日期和时间与当前实际日期和时间进行比较，并且基于比较提供开始验证输出。使用监视控制器还包括启用功能，只有在启动验证输出满足规定的标准时才能使医疗器械的操作。

3. 发明授权

US07241270B2 Systems and methods for monitoring and enabling use of a medical instrument 有权
标题翻译：用于监测和使用医疗仪器的系统和方法
公开(公告)号：US07241270B2
公开(公告)日：2007-07-10
申请号：US10202447
申请日：2002-07-24
申请人： Michael J Horzewski , Veijo T Suorsa , Todd A Thompson
发明人： Michael J Horzewski , Veijo T Suorsa , Todd A Thompson
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N2007/0073
摘要： Systems and methods monitor and enable the use of a medical instrument that is configured to be operated in a prescribed manner. The systems and methods employ a use register sized and configured to be carried by the medical instrument, which comprises a memory field for recording a start date and time at an instance of first operation of the medical instrument. The systems and methods also employ a use monitoring controller, which is adapted and configured to be coupled to the use register. The use monitoring controller includes a start validation function that compares the start date and time to a present real date and time and provides a start validation output based upon the comparison. The use monitoring controller also includes an enablement function that enables operation of the medical instrument only if the start validation output meets prescribed criteria.
摘要翻译：系统和方法监视和使用被配置为以规定的方式操作的医疗器械的使用。所述系统和方法采用由医疗器械承载的大小和构造的使用寄存器，其包括用于在医疗器械的第一次操作的情况下记录开始日期和时间的存储区域。系统和方法还采用使用监视控制器，其被适配和配置为耦合到使用寄存器。使用监视控制器包括启动验证功能，其将开始日期和时间与当前实际日期和时间进行比较，并且基于比较提供开始验证输出。使用监视控制器还包括启用功能，只有在启动验证输出满足规定的标准时才能使医疗器械的操作。

4. 发明授权

US07220232B2 Method for delivering ultrasonic energy 失效
标题翻译：提供超声波能量的方法
公开(公告)号：US07220232B2
公开(公告)日：2007-05-22
申请号：US10202407
申请日：2002-07-24
申请人： Veijo T Suorsa , Todd A Thompson , Michael J Horzewski
发明人： Veijo T Suorsa , Todd A Thompson , Michael J Horzewski
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B8/4427 , A61B8/4444 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , A61N2007/0073
摘要： Ultrasound energy is delivered to an ultrasound transducer. The ultrasound energy is delivered at an output frequency that varies over time within a range of output frequencies, and a tuning function selects from within the range an operating output frequency for the ultrasound transducer based upon preprogrammed selection rules. The ultrasound energy is delivered to the ultrasound transducer at or near the operating output frequency selected, to perform a therapeutic or diagnostic function for a specified treatment time, after which operation of the ultrasound transducer is disabled.
摘要翻译：超声能量传递到超声波换能器。超声能量以输出频率的范围内随时间变化的输出频率传送，并且调谐功能基于预编程的选择规则从超声换能器的工作输出频率范围内选择。超声能量在所选择的操作输出频率处或其附近被输送到超声波换能器，以在指定的治疗时间内执行治疗或诊断功能，之后禁用超声换能器的操作。

5. 发明授权

US06638206B2 Methods and apparatus for loading radioactive seeds into brachytherapy needles 失效
公开(公告)号：US06638206B2
公开(公告)日：2003-10-28
申请号：US09998610
申请日：2001-11-29
申请人： Thomas C Green , Michael J Horzewski , Jason Klofstad
发明人： Thomas C Green , Michael J Horzewski , Jason Klofstad
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61M5/329 , A61M2210/166 , A61N5/1007 , A61N5/1027 , A61N2005/1009 , A61N2005/101 , A61N2005/1011
摘要： Methods and apparatus are provided for loading therapeutic materials into brachytherapy needles. The apparatus comprises a loading tube with a lumen and two transverse slots, and radioactive seed and spacer cartridges slidably received within the transverse slots. The apparatus may be used in conjunction with a standard brachytherapy plunger and needle coupled to, respectively, the proximal and distal ends of the loading tube. The plunger dislodges seeds and spacers from the cartridge chambers to load the needle with a predetermined packing arrangement.

6. 发明授权

US4748982A Reinforced balloon dilatation catheter with slitted exchange sleeve and method 失效
标题翻译：增强球囊扩张导管与切口交换套管及方法
公开(公告)号：US4748982A
公开(公告)日：1988-06-07
申请号：US000653
申请日：1987-01-06
申请人： Michael J. Horzewski , Paul G. Yock
发明人： Michael J. Horzewski , Paul G. Yock
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02
CPC分类号： A61M25/104 , A61M25/0054 , A61M2025/0063 , A61M2025/0183 , A61M2025/1063 , A61M2025/107 , A61M25/0108
摘要： Balloon dilatation catheter adapted to be utilized in connection with a guiding catheter and a guide wire. The catheter comprises a flexible elongate tubular member having proximal and distal extremities and having a lumen extending therethrough. An inflatable balloon is mounted on the distal extremity of the tubular member. The interior of the inflatable balloon is in communication with the lumen. A sleeve extends through the balloon and extends rearwardly from the balloon and alongside the lumen. The sleeve has a guidewire lumen extending therethrough. The guidewire lumen is adapted to receive a guide wire extending therethrough and extending rearwardly of the flexible elongate element into a region adjacent the proximal extremity of the proximal elongate element. The sleeve has a slit extending longitudinally of the same from the proximal extremity of the sleeve to a region adjacent the balloon permitting the guide wire to be removed therethrough.

7. 发明申请

US20140046313A1 TISSUE NECROSIS METHODS AND APPARATUS 审中-公开
标题翻译：组织损伤方法和装置
公开(公告)号：US20140046313A1
公开(公告)日：2014-02-13
申请号：US13754268
申请日：2013-01-30
申请人： Michael J. Pederson , Patrick J. Phillips , John P. Madden , Michael J. Horzewski
发明人： Michael J. Pederson , Patrick J. Phillips , John P. Madden , Michael J. Horzewski
IPC分类号： A61N7/02
CPC分类号： A61N7/02 , A61B17/2202 , A61B17/3478 , A61B2017/22021 , A61B2018/00011 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61N7/022 , A61N2007/0043 , A61N2007/0052 , A61N2007/0069 , A61N2007/0078 , A61N2007/0091 , A61N2007/0095
摘要： Apparatus and methods for creating tissue necrosis include an energy delivery apparatus that can be positioned adjacent a target treatment site such as a vessel without direct contact with the treatment site tissue. Collimated energy is then directed to the vessel to create necrotic regions in the tissue. Exemplary use in renal vessels creates necrotic regions in adjacent nerves which can alleviate hypertension in a patient.
摘要翻译：用于产生组织坏死的装置和方法包括能量输送装置，其能够定位在诸如血管的目标治疗部位附近而不与治疗部位组织直接接触。然后将准直的能量引导至血管以在组织中产生坏死区域。在肾血管中的示例性用途在相邻神经中产生可以减轻患者高血压的坏死区域。

8. 发明申请

US20080208084A1 Systems and methods for applying ultrasound energy to increase tissue perfusion and/or vasodilation without substantial deep heating of tissue 审中-公开
标题翻译：用于施加超声能量以增加组织灌注和/或血管舒张的系统和方法而没有对组织的大量深度加热
公开(公告)号：US20080208084A1
公开(公告)日：2008-08-28
申请号：US12082627
申请日：2008-04-11
申请人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
发明人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B90/50 , A61B2017/00725 , A61B2017/00734 , A61B2018/00023 , H04N1/387 , H04N1/58
摘要： Systems and methods apply ultrasound energy to achieve vasodilation and/or to increase tissue perfusion without causing substantial deep tissue heating.
摘要翻译：系统和方法应用超声波能量以实现血管舒张和/或增加组织灌注而不引起显着的深层组织加热。

9. 发明授权

US07229423B2 Systems and methods for applying audible acoustic energy to increase tissue perfusion and/or vasodilation 失效
公开(公告)号：US07229423B2
公开(公告)日：2007-06-12
申请号：US10359040
申请日：2003-02-05
申请人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
发明人： Michael J. Horzewski , Veijo T. Suorsa , Todd A. Thompson
IPC分类号： A61H1/00
CPC分类号： A61H23/0236 , A61H2205/08 , A61N7/00
摘要： Systems and methods apply audible acoustic energy to cause vasodilation and/or to increase tissue perfusion.

10. 发明授权

US07101333B2 Methods and apparatus for loading radioactive seeds into brachytherapy needles 失效
公开(公告)号：US07101333B2
公开(公告)日：2006-09-05
申请号：US10693598
申请日：2003-10-23
申请人： Thomas C. Green , Michael J. Horzewski , Jason Klofstad
发明人： Thomas C. Green , Michael J. Horzewski , Jason Klofstad
IPC分类号： A61M36/00 , A61M5/00
CPC分类号： A61M37/0069 , A61M5/329 , A61M2210/166 , A61N5/1007 , A61N5/1027 , A61N2005/1009 , A61N2005/101 , A61N2005/1011
摘要： Methods and apparatus are provided for loading therapeutic materials into brachytherapy needles. The apparatus comprises a loading tube with a lumen and two transverse slots, and radioactive seed and spacer cartridges slidably received within the transverse slots. The apparatus may be used in conjunction with a standard brachytherapy plunger and needle coupled to, respectively, the proximal and distal ends of the loading tube. The plunger dislodges seeds and spacers from the cartridge chambers to load the needle with a predetermined packing arrangement.

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