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1. 发明授权

US09371301B2 Prenylarene compound and use thereof 有权
标题翻译：普萘酰芳烃化合物及其用途
公开(公告)号：US09371301B2
公开(公告)日：2016-06-21
申请号：US13696425
申请日：2011-05-06
申请人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Takashi Kawachi
发明人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Takashi Kawachi
IPC分类号： C07D307/36 , C07D333/06 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08
CPC分类号： C07D307/36 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08 , A61K2300/00
摘要： A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms, and R106 represents a hydrogen atom, or a saturated or unsaturated hydrocarbon group which is a straight or branched chain having 1 to 12 carbon atoms, but excluded is the case where R101 is a 3-furyl group, R102, R103, R104 and R105 are all methyl groups, and R106 is a methyl group, a 4-methyl-3-pentenyl group or a 4,8-dimethyl-3,7-nonadienyl group); or a pharmaceutically acceptable salt thereof has selective inhibitory activity on hypoxic cell growth in a broad range of the concentration and therefore is useful as an active ingredient of a medicament for cancer prevention or treatment.
摘要翻译：由通式（C）表示的化合物：（其中R 101表示取代或未取代的芳族杂环基，R 102，R 103，R 104和R 105可以相同或不同，表示氢原子，卤素原子，烷基具有1至3个碳原子的烷基或具有1至3个碳原子的卤代烷基，R 10 6表示氢原子，或具有1至12个碳原子的直链或支链的饱和或不饱和烃基，但不包括 R 101为3-呋喃基的情况，R102，R103，R104，R105均为甲基，R106为甲基，4-甲基-3-戊烯基或4,8-二甲基-3,7 - 壬二烯基）; 或其药学上可接受的盐在宽范围的浓度下对缺氧细胞生长具有选择性抑制活性，因此可用作用于癌症预防或治疗的药物的活性成分。

2. 发明授权

US07931706B2 Method and apparatus for fermentation 有权
标题翻译：发酵方法和装置
公开(公告)号：US07931706B2
公开(公告)日：2011-04-26
申请号：US11902247
申请日：2007-09-20
申请人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
发明人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
IPC分类号： C10L5/00
CPC分类号： C10L5/46 , F23G2206/201 , F23G2900/50208 , Y02E20/363 , Y02E50/10 , Y02E50/30
摘要： A cement kiln from which its brick lining has been removed, or a rotary dryer for cement production is used as a fermentation treatment apparatus 202 for converting waste matter into compost. The waste matter to be subjected to the fermentation treatment includes city waste contained in garbage bags, and its fermentation treatment is carried out by introducing the waste matter directly into the aforesaid cement kiln or the aforesaid rotary dryer for cement production without tearing the aforesaid garbage bags.
摘要翻译：作为用于将废物转化为堆肥的发酵处理装置202，使用从其排除砖衬的水泥窑或用于水泥生产的旋转干燥器。要进行发酵处理的废物包括垃圾袋中所含的城市废物，其发酵处理是通过将废物直接引入上述水泥窑或上述用于水泥生产的旋转干燥器中进行的，而不会撕裂上述垃圾袋。

3. 发明授权

US07285141B2 Method and apparatus for fermentation 有权
标题翻译：发酵方法和装置
公开(公告)号：US07285141B2
公开(公告)日：2007-10-23
申请号：US10101541
申请日：2002-03-20
申请人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
发明人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
IPC分类号： C10L5/00 , C10L5/40
CPC分类号： C10L5/46 , F23G2206/201 , F23G2900/50208 , Y02E20/363 , Y02E50/10 , Y02E50/30
摘要： A cement kiln from which its brick lining has been removed, or a rotary dryer for cement production is used as a fermentation treatment apparatus 202 for converting waste matter into compost. The waste matter to be subjected to the fermentation treatment includes city waste contained in garbage bags, and its fermentation treatment is carried out by introducing the waste matter directly into the aforesaid cement kiln or the aforesaid rotary dryer for cement production without tearing the aforesaid garbage bags.
摘要翻译：作为用于将废物转化为堆肥的发酵处理装置202，使用从其排除砖衬的水泥窑或用于水泥生产的旋转干燥器。要进行发酵处理的废物包括垃圾袋中所含的城市废物，其发酵处理是通过将废物直接引入上述水泥窑或上述用于水泥生产的旋转干燥器中进行的，而不会撕裂上述垃圾袋。

4. 发明申请

US20070273852A1 Exposure Apparatus, Exposure Method, Device Manufacturing Method, and System 有权
标题翻译：曝光装置，曝光方法，装置制造方法和系统
公开(公告)号：US20070273852A1
公开(公告)日：2007-11-29
申请号：US11662591
申请日：2006-06-30
申请人： Masayoshi Arai
发明人： Masayoshi Arai
IPC分类号： G03B27/42 , G03B27/52
CPC分类号： G03F7/70458 , G03F7/7005 , G03F7/70525 , G03F7/70558 , G03F7/70575 , G03F7/70625 , H01S3/10069 , H01S3/1055 , H01S3/1394 , H01S3/225 , H01S2301/08
摘要： An exposure apparatus is equipped with a laser unit that emits a laser beam, a memory that stores a first information which shows a first relation indicating a relation between a linewidth error of a pattern formed on a wafer and a spectral characteristic of the laser beam emitted from the laser unit, and a main controller that controls the spectral width of the laser beam via a laser controller, based on the first information and on information related to a reticle that is to be used. Main controller performs spectral width control of the laser beam so as to suppress linewidth error, based on the first information and on the information related to the reticle that is to be used.
摘要翻译：曝光装置配备有发射激光束的激光单元，存储第一信息的存储器，该第一信息表示表示晶片上形成的图案的线宽误差与发射的激光束的光谱特性之间的关系的第一关系以及通过激光控制器控制激光束的光谱宽度的主控制器，基于第一信息和与要使用的掩模版有关的信息。主控制器根据第一信息和与要使用的掩模版有关的信息，进行激光束的光谱宽度控制，以抑制线宽误差。

5. 发明申请

US20050176655A1 Novel macrolide derivatives havaing effect of potentiating antifungal activity 失效
标题翻译：新型大环内酯衍生物具有增强抗真菌活性的作用
公开(公告)号：US20050176655A1
公开(公告)日：2005-08-11
申请号：US10472044
申请日：2002-10-29
申请人： Satoshi Omura , Hiroshi Tomoda , Toshiaki Sunazuka , Masayoshi Arai , Tohru Nagamitsu
发明人： Satoshi Omura , Hiroshi Tomoda , Toshiaki Sunazuka , Masayoshi Arai , Tohru Nagamitsu
IPC分类号： A01N43/04 , A61K31/7048 , A61P31/10 , C07H17/08
CPC分类号： C07H17/08 , A61K31/7048
摘要： Macrolide derivatives having enhancing effect for activities of azole antifungal agents, acting at low concentration and within a short time against fungal infection and reducing the frequency of appearance of resistant microorganisms. One such substance is a compound represented by the formula [I]: wherein R1 is Ac, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is H, when R1 Bzl, R2 and R3 are Bzl, and R4 is Me; when R1 is Ac, R2 and R3 are Pr, and R4 is Me; when R1 is Ac, R2 and R3 are Hex, and R4 is Me; when R1 is Ac, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 and R3 are Pr, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is Me; when R1 is H, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 is H, R3 is Bzl, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is H, or when R1 is H, R2 and R3 are Hex, and R4 is Et.
摘要翻译：大环内酯衍生物对唑类抗真菌剂的活性具有增强的作用，在低浓度和短时间内对真菌感染起作用，并降低抗性微生物出现的频率。一种这样的物质是由式[I]表示的化合物：其中R1是Ac，R2和R3是Ac，R4是Me; 当R1为H时，R2和R3为Ac，R4为Me; 当R1为H时，R2和R3为Ac，R4为H时，当R1Bz1，R2和R3为Bz1，R4为Me时; 当R1为Ac时，R2和R3为Pr，R4为Me; 当R1为Ac时，R2和R3为Hex，R4为Me; 当R1为Ac时，R2和R3为Bz1，R4为Me; 当R1为H时，R2和R3为Pr，R4为Me; 当R1为H时，R2和R3为Hex，R4为Me; 当R1为H时，R2和R3为Bz1，R4为Me; 当R1为H时，R2为H，R3为Bz1，R4为Me; 当R1为H时，R2和R3为Hex，R4为H，或当R1为H时，R2和R3为Hex，R4为Et。

6. 发明授权

US08791263B2 Cortistatin A analog and use thereof 有权
标题翻译：皮质他汀类似物及其用途
公开(公告)号：US08791263B2
公开(公告)日：2014-07-29
申请号：US13823265
申请日：2011-09-16
申请人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Satoru Tamura
发明人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Satoru Tamura
IPC分类号： C07D405/04 , C07D217/02 , A61K45/00 , A61K31/4725 , A61P43/00 , A61P35/00 , C07D407/10 , C07F7/18 , A61K45/06
CPC分类号： C07D407/10 , A61K31/4725 , A61K45/06 , C07D405/04 , C07F7/1804
摘要： A compound represented by the general formula (M): (wherein R1 represents a substituted or unsubstituted aromatic heterocyclic group, R2 represents a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 3 carbon atoms, OR3, N(R3)2, C(═O)OR3 or C(═O)N(R3)2, R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 4 carbon atoms, R4 represents a hydrogen atom, an oxygen atom or OR5, and R5 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an acyl group having 1 to 3 carbon atoms); or a pharmaceutically acceptable salt thereof is a cortistatin A analog which is useful as an active ingredient of medicaments for cancer prevention or treatment in that the analog can be mass-produced by chemical synthesis due to its simple chemical structure and retains the same biological activities as those of cortistatin A.
摘要翻译：由通式（M）表示的化合物：其中，R1表示取代或未取代的芳香族杂环基，R2表示氢原子，取代或未取代的碳原子数1〜3的烷基，OR3，N（R3）2， C（= O）OR 3或C（= O）N（R3）2，R3表示氢原子，碳原子数1〜4的烷基或碳原子数1〜4的酰基，R4表示氢原子，氧原子或OR 5，R5表示氢原子，碳原子数1〜3的烷基或碳原子数1〜3的酰基）。或其药学上可接受的盐是可用作癌症预防或治疗药物的活性成分的皮质激素A类似物，因为类似物可以通过化学合成由于其简单的化学结构而大规模生产，并保持与皮质激素A.

7. 发明申请

US20130065937A1 NOVEL PRENYLARENE COMPOUND AND USE THEREOF 有权
标题翻译：新颖的苯乙烯化合物及其用途
公开(公告)号：US20130065937A1
公开(公告)日：2013-03-14
申请号：US13696425
申请日：2011-05-06
申请人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Takashi Kawachi
发明人： Motomasa Kobayashi , Naoyuki Kotoku , Masayoshi Arai , Takashi Kawachi
IPC分类号： C07D333/08 , A61P35/00 , A61K31/341 , A61K31/381 , C07D307/36
CPC分类号： C07D307/36 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08 , A61K2300/00
摘要： A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms, and R106 represents a hydrogen atom, or a saturated or unsaturated hydrocarbon group which is a straight or branched chain having 1 to 12 carbon atoms, but excluded is the case where R101 is a 3-furyl group, R102, R103, R104 and R105 are all methyl groups, and R106 is a methyl group, a 4-methyl-3-pentenyl group or a 4,8-dimethyl-3,7-nonadienyl group); or a pharmaceutically acceptable salt thereof has selective inhibitory activity on hypoxic cell growth in a broad range of the concentration and therefore is useful as an active ingredient of a medicament for cancer prevention or treatment.
摘要翻译：由通式（C）表示的化合物：（其中R 101表示取代或未取代的芳族杂环基，R 102，R 103，R 104和R 105可以相同或不同，表示氢原子，卤素原子，烷基具有1至3个碳原子的烷基或具有1至3个碳原子的卤代烷基，R 10 6表示氢原子，或具有1至12个碳原子的直链或支链的饱和或不饱和烃基，但不包括 R 101为3-呋喃基的情况，R102，R103，R104，R105均为甲基，R106为甲基，4-甲基-3-戊烯基或4,8-二甲基-3,7 - 壬二烯基）; 或其药学上可接受的盐在宽范围的浓度下对缺氧细胞生长具有选择性抑制活性，因此可用作用于癌症预防或治疗的药物的活性成分。

8. 发明授权

US08025087B2 Ultrasonic vibration welder 有权
标题翻译：超声波振动焊机
公开(公告)号：US08025087B2
公开(公告)日：2011-09-27
申请号：US12670321
申请日：2008-07-23
申请人： Masayoshi Arai , Shigetomi Morita
发明人： Masayoshi Arai , Shigetomi Morita
IPC分类号： B32B37/00
CPC分类号： B29C66/8227 , B23K20/106 , B29C65/08 , B29C66/1122 , B29C66/43 , B29C66/80 , B29C66/81433 , B29C66/8167 , B29C66/8322 , B29C66/9513
摘要： The present invention solves the problem that a connecting portion between a horn and a vibration transmission rod has a tendency to get damaged and the problem associated with the structure in which a chip is attached to an end of the vibration transmission rod, which occur with the known ultrasonic vibration welder. A vibration transmission rod has an end surface serving as a vibration-and-pressure application surface, and a polygonal cross section. The vibration transmission rod is disposed at an end of a horn in such a manner that they vibrate together. The vibration transmission rod and a mass are formed separately. The mass applies pressure to a projection formed at a nodal point of the vibration transmission rod.
摘要翻译：本发明解决了喇叭和振动传动杆之间的连接部分具有被损坏的倾向的问题，以及与传动杆端部附接有芯片的结构有关的问题，已知超声波振动焊机。振动传递杆具有用作振动和压力施加表面的端面和多边形横截面。振动传递杆以它们一起振动的方式设置在喇叭的一端。振动传递杆和质量分别形成。质量对形成在振动传递杆的节点处的突起施加压力。

9. 发明申请

US20090201479A1 LASER LIGHT SOURCE CONTROL METHOD, LASER LIGHT SOURCE DEVICE, AND EXPOSURE APPARATUS 审中-公开
标题翻译：激光光源控制方法，激光光源装置和曝光装置
公开(公告)号：US20090201479A1
公开(公告)日：2009-08-13
申请号：US11814997
申请日：2006-01-30
申请人： Masayoshi Arai
发明人： Masayoshi Arai
IPC分类号： G03B27/54 , G03B27/32 , H01S3/10
CPC分类号： H01S3/225 , B23K26/032 , B23K26/064 , B23K26/0643 , B23K26/0648 , B23K26/0665 , B23K26/705 , G03F7/70041 , G03F7/70566 , G03F7/70575 , G03F7/7085 , H01S3/0014 , H01S3/10061 , H01S3/10069 , H01S3/101 , H01S3/104 , H01S3/1308 , H01S3/134
摘要： An exposure apparatus includes a laser light source that emits a laser beam as an exposure beam by pulse oscillation; a detection system that detects a rotation angle of an external shape of the laser beam emitted by the pulse oscillation from a corresponding laser light source; and a control device that controls a rotation angle of the external shape of the laser beam or a rotation angle of a linearly polarized light component of a corresponding laser beam or both of them, based on the rotation angle detected by the detection system.
摘要翻译：曝光装置包括通过脉冲振荡发射激光束作为曝光光束的激光光源; 检测系统，其从相应的激光光源检测由脉冲振荡发射的激光束的外部形状的旋转角度; 以及控制装置，其基于由检测系统检测到的旋转角度来控制激光束的外部形状的旋转角度或相应的激光束的线偏振光分量的旋转角度或两者的旋转角度。

10. 发明申请

US20100206487A1 ULTRASONIC VIBRATION WELDER 有权
标题翻译：超声波振动焊机
公开(公告)号：US20100206487A1
公开(公告)日：2010-08-19
申请号：US12670321
申请日：2008-07-23
申请人： Masayoshi Arai , Shigetomi Morita
发明人： Masayoshi Arai , Shigetomi Morita
IPC分类号： B23K1/06 , B32B37/00
CPC分类号： B29C66/8227 , B23K20/106 , B29C65/08 , B29C66/1122 , B29C66/43 , B29C66/80 , B29C66/81433 , B29C66/8167 , B29C66/8322 , B29C66/9513
摘要： The present invention solves the problem that a connecting portion between a horn and a vibration transmission rod has a tendency to get damaged and the problem associated with the structure in which a chip is attached to an end of the vibration transmission rod, which occur with the known ultrasonic vibration welder. A vibration transmission rod has an end surface serving as a vibration-and-pressure application surface, and a polygonal cross section. The vibration transmission rod is disposed at an end of a horn in such a manner that they vibrate together. The vibration transmission rod and a mass are formed separately. The mass applies pressure to a projection formed at a nodal point of the vibration transmission rod.
摘要翻译：本发明解决了喇叭和振动传动杆之间的连接部分具有被损坏的倾向的问题，以及与传动杆端部附接有芯片的结构有关的问题，已知超声波振动焊机。振动传递杆具有用作振动和压力施加表面的端面和多边形横截面。振动传递杆以它们一起振动的方式设置在喇叭的一端。振动传递杆和质量分别形成。质量对形成在振动传递杆的节点处的突起施加压力。

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