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1. 发明申请

US20130237330A1 SHELL-TYPE NEEDLE BEARING AND CROSS-TYPE UNIVERSAL JOINT 有权
标题翻译：壳型轴承和交叉型通用接头
公开(公告)号：US20130237330A1
公开(公告)日：2013-09-12
申请号：US13699674
申请日：2012-01-25
申请人： Masato Higuchi , Eisho Watanabe
发明人： Masato Higuchi , Eisho Watanabe
IPC分类号： F16D3/41 , F16C19/44 , F16C33/58 , F16C19/26
CPC分类号： F16D3/41 , F16C19/225 , F16C19/26 , F16C19/44 , F16C21/005 , F16C33/58 , F16C33/586 , F16C33/588 , F16C33/64 , F16C33/7809 , F16C33/7823 , F16C33/7886 , F16C33/7889 , F16C2361/41 , F16D3/385 , Y02T10/865
摘要： Construction is achieved of a cross-type universal joint and a shell-type needle bearing that is used therein for which cost can be lowered and durability can be maintained by suitably maintaining the seal performance even when used in severe operating conditions. The portions on the outer surface of the shell-type outer ring 9a for which there is a possible of coming in sliding contact with the tip end edges of at least two seal lips 17, 18 of a plurality of seal lips of a seal ring 14 are selectively covered with a corrosion resistant coating. Preferably, the entire outer surface of the shell-type outer ring is covered by a chemically treated film having anti-corrosion properties.
摘要翻译：通过使用十字型万向接头和壳型滚针轴承来实现，即使在苛刻的操作条件下使用时也可以适当地保持密封性能，可以降低成本并保持耐久性。壳型外圈9a的外表面上的可能与密封环14的多个密封唇的至少两个密封唇17,18的前端缘滑动接触的部分选择性地覆盖有耐腐蚀涂层。优选地，壳型外圈的整个外表面被具有防腐蚀性能的化学处理膜覆盖。

2. 发明授权

US07752747B2 Manufacturing method of electronic component 有权
标题翻译：电子元件制造方法
公开(公告)号：US07752747B2
公开(公告)日：2010-07-13
申请号：US10595988
申请日：2004-12-07
申请人： Masato Higuchi , Hideki Shinkai , Osamu Ishikawa
发明人： Masato Higuchi , Hideki Shinkai , Osamu Ishikawa
IPC分类号： H05K3/30
CPC分类号： H03H9/1085 , H01L21/561 , H01L21/566 , H01L21/67126 , H01L24/97 , H01L2224/16225 , H01L2224/97 , H01L2924/00011 , H01L2924/00014 , H01L2924/01012 , H01L2924/0102 , H01L2924/01068 , H01L2924/01078 , H01L2924/01079 , H01L2924/09701 , H01L2924/181 , Y10T29/42 , Y10T29/435 , Y10T29/4913 , Y10T29/49146 , Y10T29/49158 , Y10T29/49171 , Y10T29/49172 , H01L2224/81 , H01L2924/00 , H01L2224/0401
摘要： A method of manufacturing an electronic component minimizes the occurrence of voids and degradation of characteristics in a resin-sealed portion, while reducing the costs thereof. A sealing step for sealing surface acoustic wave elements by a sealing resin member formed from a resin film is performed by mounting the surface acoustic wave elements on a collective mounting substrate and the resin film in a bag with a gas-barrier property, and causing the resin film to infiltrate between the surface acoustic wave elements mounted on the reduce-pressured-packed collective mounting substrate to be hermetically sealed by the pressure difference between the inside and the outside of the bag.
摘要翻译：电子部件的制造方法使树脂密封部的空隙的发生和特性的劣化最小化，同时降低成本。通过由树脂膜形成的密封树脂构件来密封声表面波元件的密封步骤是通过将表面声波元件安装在集体安装基板上，并将树脂膜安装在具有阻气性的袋中，在安装在减压加压集合安装基板上的声表面波元件之间渗透的树脂膜被气袋内外的压力差气密密封。

3. 发明申请

US20090005540A1 Method For Removing Sialic Acid and Method For Producing Asialoerythropoietin 审中-公开
标题翻译：去除唾液酸的方法和生产Asialo促红细胞生成素的方法
公开(公告)号：US20090005540A1
公开(公告)日：2009-01-01
申请号：US12087945
申请日：2007-01-18
申请人： Masato Higuchi
发明人： Masato Higuchi
IPC分类号： C07K14/00 , C07H1/06
CPC分类号： C07K14/505
摘要： The object is to provide a method for removing a sialic acid that can be carried out simply at a low cost and a method for producing asialoerythropoietin using the same. The method for removing a sialic acid according to the present invention includes an acidifying and heating process of acidifying and heating a solution containing erythropoietin so as to remove a sialic acid bonded to an erythropoietin molecule. Further, the method for producing asialoerythropoietin according to the present invention includes a sialic acid removing process of removing a sialic acid bonded to an erythropoietin molecule by the method for removing a sialic acid according to the present invention.
摘要翻译：本发明的目的是提供一种可以简单地以低成本除去唾液酸的方法，以及使用该方法制备唾液促红细胞生成素的方法。根据本发明的除去唾液酸的方法包括酸化和加热含有促红细胞生成素的溶液的酸化和加热方法，以除去与红细胞生成素分子结合的唾液酸。此外，本发明的唾液酸促生成素的制造方法包括通过本发明的除去唾液酸的方法除去与红细胞生成素分子结合的唾液酸的唾液酸去除方法。

4. 发明授权

US09034789B2 Adsorption carbon, and adsorbent 有权
标题翻译：吸附碳和吸附剂
公开(公告)号：US09034789B2
公开(公告)日：2015-05-19
申请号：US13583181
申请日：2011-03-02
申请人： Masato Higuchi , Takao Kimura , Masayoshi Takeuchi , Kisaburo Deguchi
发明人： Masato Higuchi , Takao Kimura , Masayoshi Takeuchi , Kisaburo Deguchi
IPC分类号： B01J20/20 , A61K33/44 , B01J20/28 , B01J20/30
CPC分类号： A61K33/44 , B01J20/20 , B01J20/28069 , B01J20/2808 , B01J20/3078
摘要： Provided are an adsorptive carbon which can effectively adsorb vivotoxins such as advanced glycation end products (AGEs), and an adsorbent containing the adsorptive carbon as an active ingredient. The adsorptive carbon according to the present invention has a total pore volume of 0.10 to 1.0 mL/g, an average pore diameter of 1.0 to 2.0 nm, and an absorbance of an infrared absorption band at 1650-1800 cm−1 of no less than 0.005.
摘要翻译：提供了可以有效吸附诸如晚期糖基化终产物（AGEs）等生物毒素和含有吸附性碳的吸附剂作为活性成分的吸附碳。根据本发明的吸附碳的总孔体积为0.10〜1.0mL / g，平均孔径为1.0〜2.0nm，1650〜1800cm -1的红外吸收带的吸光度不小于 0.005。

5. 发明授权

US08547714B2 Output inverter for single phase and output current detecting method thereof 有权
标题翻译：单相输出逆变器及其输出电流检测方法
公开(公告)号：US08547714B2
公开(公告)日：2013-10-01
申请号：US12161066
申请日：2006-12-25
申请人： Masato Higuchi
发明人： Masato Higuchi
IPC分类号： H02H7/122 , H02H9/02
CPC分类号： H02M7/53871 , H02M7/5387 , H02M2001/0009
摘要： There are provided an output inverter for single phase which can detect a current with high precision through a smaller number of components, and an output current detecting method thereof. A first current detector (6) is disposed between a positive electrode P side of a DC power supply and a parallel connector (1) in a first arm (8), a second current detector (7) is disposed between a negative electrode N side of the DC power supply and a parallel connector (4) in a second arm (9), a current in a first convection mode is detected by the first current detector (6), a current in a second convection mode is detected by the second current detector (7), and an output current is detected from signals output from the first current detector (6) and the second current detector (7).
摘要翻译：提供了一种用于单相的输出反相器，其可以通过较少数量的部件以高精度检测电流，以及其输出电流检测方法。第一电流检测器（6）设置在直流电源的正电极P侧和第一臂（8）中的并联连接器（1）之间，第二电流检测器（7）设置在负极N侧的直流电源和第二臂（9）中的并联连接器（4），由第一电流检测器（6）检测第一对流模式的电流，第二对流模式中的电流被第二对流模式电流检测器（7），并且从从第一电流检测器（6）和第二电流检测器（7）输出的信号检测输出电流。

6. 发明授权

US08537550B2 Wiring board and power conversion device 失效
标题翻译：接线板和电源转换装置
公开(公告)号：US08537550B2
公开(公告)日：2013-09-17
申请号：US13329423
申请日：2011-12-19
申请人： Masato Higuchi , Yasuhiko Kawanami , Katsushi Terazono , Koji Higashikawa , Akira Sasaki , Takayuki Morihara , Takashi Aoki , Tetsuya Ito , Yukihisa Nakabayashi , Tasuku Isobe , Kiyonori Koguma
发明人： Masato Higuchi , Yasuhiko Kawanami , Katsushi Terazono , Koji Higashikawa , Akira Sasaki , Takayuki Morihara , Takashi Aoki , Tetsuya Ito , Yukihisa Nakabayashi , Tasuku Isobe , Kiyonori Koguma
IPC分类号： H05K7/20
CPC分类号： H01L23/473 , H01L25/112 , H01L2224/16225 , H01L2224/32225 , H01L2924/1305 , H01L2924/13055 , H01L2924/13091 , H01L2924/3011 , H02M7/003 , H01L2924/00
摘要： A wiring board includes a conductor plate including a wiring portion and an electrode portion connected to a power conversion semiconductor element, a liquid-cooling pipe mounted near the conductor plate and causing a cooling liquid to be supplied therethrough, and an insulating resin material arranged at least between the conductor plate and the liquid-cooling pipe.
摘要翻译：布线基板包括：导体板，包括布线部分和连接到功率转换半导体元件的电极部分;液体冷却管，安装在导体板附近并使冷却液供应到其中;以及绝缘树脂材料，布置在至少在导体板和液体冷却管之间。

7. 发明申请

US20120207421A1 OUTER RING FOR A SHELL-TYPE RADIAL NEEDLE BEARING AND MANUFACTURING METHOD THEREOF 有权
标题翻译：壳型径向轴承的外圈及其制造方法
公开(公告)号：US20120207421A1
公开(公告)日：2012-08-16
申请号：US13391933
申请日：2011-09-22
申请人： Masato Higuchi , Noriyuki Takeo , Yoshiaki Komura
发明人： Masato Higuchi , Noriyuki Takeo , Yoshiaki Komura
IPC分类号： F16C33/58 , B21D53/10 , C21D7/06
CPC分类号： B21D53/12 , B21D53/10 , B24C1/10 , F16C19/466 , F16C21/005 , F16C33/588 , F16C33/64 , F16C2220/40 , F16C2220/42 , F16C2240/18 , F16C2361/41 , F16D3/385 , F16D3/41 , Y10T29/49689
摘要： An outer ring 6a for a shell-type radial needle bearing having a cylindrical shape with a bottom is achieved for which fatigue life of the bottom plate section 9a and the continuous section between the bottom plate section 9a and the cylindrical section 8a is improved, as well as the anti-corrosion characteristic of the outer ring 6a is improved and the outer ring 6a can be prevented from coming out of the bearing without an increase in cost. After obtaining an intermediate raw material 35 having a cylindrical section and a bottom plate section from a metal raw material, shot peening is performed on the intermediate material 35 to create residual compressive stress in the surface and surface layer section on the outer surface side of the cylindrical section 8a and the bottom plate section 9a such that the residual compressive stress in the surface layer section on the outer surface side is greater than the in the surface layer section on the inner surface side, and from the surface to a depth of 0.03 mm is 700 MPa to 1600 MPa.
摘要翻译：实现了具有底部圆柱形的壳型径向滚针轴承的外圈6a，底板部9a和底板部9a与圆筒部8a之间的连续部分的疲劳寿命得到改善，如并且外圈6a的防锈特性得到改善，并且可以防止外圈6a从轴承中脱出而不增加成本。在从金属原料获得具有圆筒形部分和底板部分的中间原料35之后，对中间材料35进行喷丸硬化，以在中间材料35的外表面侧的表面和表层部分产生残留的压缩应力圆筒部8a和底板部9a，使得外表面侧的表层部的残留压缩应力大于内表面侧的表层部，并且从表面到0.03mm的深度为700MPa〜1600MPa。

8. 发明申请

US20050092154A1 Cutter apparatus for flat plate building material 审中-公开
标题翻译：平板建筑材料切割机
公开(公告)号：US20050092154A1
公开(公告)日：2005-05-05
申请号：US10730987
申请日：2003-12-10
申请人： Masato Higuchi
发明人： Masato Higuchi
IPC分类号： B28D1/24 , B23D47/04 , B26D1/143 , B27B5/06 , B28D1/04 , B26D5/08 , B26D1/14
CPC分类号： B23D47/045 , B27B5/063 , B28D1/04 , Y10T83/7697 , Y10T83/869
摘要： A cutter apparatus for a flat plate building material according to the present invention comprises: an inclined base having a slope; a cutter having a rotary blade for cutting a slipping-down flat plate building material; and cutter fixing means for installing the rotary blade at a predetermined height from the slope, the cutter fixing means comprising: a cutter rail trained between the opposite ends of the inclined base in the direction of the width of the base; a movable support section movable along the cutter rail; and a cutter holder mounted on the movable support section for supporting a casing of the cutter.
摘要翻译：根据本发明的用于平板建筑材料的切割装置包括：具有斜面的倾斜基座; 具有用于切割平滑平板建筑材料的旋转刀片的切割器; 以及切割器固定装置，用于将旋转刀片安装在与斜面相同的预定高度处，刀具固定装置包括：在基座的宽度方向上在倾斜基座的相对端之间经过训练的刀轨; 可移动支撑部分，其可沿着所述切割器轨道移动; 以及安装在所述可动支撑部上用于支撑所述切割器的壳体的刀架。

9. 发明授权

US06268336B1 Pharmaceutical composition for treatment of hepatic diseases 失效
标题翻译：用于治疗肝病的药物组合物
公开(公告)号：US06268336B1
公开(公告)日：2001-07-31
申请号：US09202614
申请日：1998-12-18
申请人： Yoshiro Niitsu , Junji Kato , Masato Higuchi
发明人： Yoshiro Niitsu , Junji Kato , Masato Higuchi
IPC分类号： A61K3816
CPC分类号： A61K38/1816
摘要： The present invention relates to a pharmaceutical composition for treatment of hepatic diseases which comprises erythropoietin as an active ingredient to reduce excess iron ions in the liver of a mammal with hepatic diseases, thus improving hepatic functions of said mammal. According to the present pharmaceutical composition with erythropoietin as an active ingredient, excess iron ions in the liver of a mammal with hepatic diseases can be decreased, so it is effective for treatment of chronic hepatitis, hepatic carcinoma, hepatocirrhosis etc. due to excess iron ions. Further, patient's anemia accompanying venesection can be prevented while excretion of excess iron ions can be promoted by using the venesection therapy in combination with the administration of said pharmaceutical composition. Furthermore, the pharmaceutical composition of the present invention is administered into a patient with chronic hepatitis C for whom IFN therapy is not effective to improve hepatic functions after which conventional IFN therapy is conducted whereby its therapeutic effect on said hepatitis can be expected.
摘要翻译：本发明涉及一种用于治疗肝病的药物组合物，其包含红细胞生成素作为活性成分，以减少具有肝脏疾病的哺乳动物肝脏中过量的铁离子，从而改善所述哺乳动物的肝功能。根据本发明的具有红细胞生成素作为活性成分的药物组合物，可以减少具有肝脏疾病的哺乳动物肝脏中的过量铁离子，因此由于过量的铁离子对治疗慢性肝炎，肝癌，肝硬化等有效。此外，通过与所述药物组合物的给药相结合，可以通过使用Venesection治疗来促进排泄过量铁离子，同时可以预防患有血液循环的贫血。此外，将本发明的药物组合物施用于慢性丙型肝炎患者，其中IFN治疗对于改善肝功能无效，之后进行常规IFN治疗，从而可以预期其对所述肝炎的治疗效果。

10. 发明授权

US5856444A Thrombocytopoiesis stimulating factor 失效
标题翻译：血小板生成刺激因子
公开(公告)号：US5856444A
公开(公告)日：1999-01-05
申请号：US849073
申请日：1997-07-18
申请人： Makoto Kawakita , Hiromitsu Matsuzaki , Kiyoshi Takatsuki , Kazushi Shibuya , Masato Higuchi
发明人： Makoto Kawakita , Hiromitsu Matsuzaki , Kiyoshi Takatsuki , Kazushi Shibuya , Masato Higuchi
IPC分类号： A61K38/00 , C07K14/475 , C07K14/52 , C07K1/18
CPC分类号： C07K14/475 , C07K14/524 , A61K38/00
摘要： An object of the present invention is to provide a physiologically active substance having activity in acting on the megakaryocyte-platelet system, in promoting the differentiation and maturation of megakaryocytes, and in promoting the formation of platelets. The present invention relates to a thrombocytopoiesis stimulating factor, characterized in having the following amino acid sequence in its molecule, and to a medicinal composition for treating thrombocytopenia, characterized in containing thrombocytopoiesis stimulating factor as an active component: Xaa Gly Asn Asn Asp Glu Ser Asn Ile Ser Phe Lys Glu Lys Asp Ile (where Xaa indicates that the amino acid is unspecified). The physiologically active substance is useful as an active component or the like in therapeutics and preventives for thrombocytopenia and thrombocytopenic purpura associated with chemotherapy and marrow grafts, and for various other diseases which are prone to bleeding attributed to thrombocytopenia.
摘要翻译： PCT No.PCT / JP95 / 04226 Sec。 371日期1997年7月18日 102（e）日期1997年7月18日PCT提交1995年11月30日PCT公布。公开号WO96 / 16987 日本6月6日，本发明的目的是提供一种在巨核细胞 - 血小板系统上具有活性的生理活性物质，促进巨核细胞的分化和成熟，促进血小板的形成。本发明涉及一种血小板生成刺激因子，其特征在于在其分子中具有以下氨基酸序列，以及用于治疗血小板减少症的药物组合物，其特征在于含有血小板生成刺激因子作为活性成分：Xaa Gly Asn Asn Asp Glu Ser Asn Ile Ser Phe Lys Glu Lys Asp Ile（其中Xaa表示氨基酸未被指定）。生理活性物质可用作与化学疗法和骨髓移植物相关的血小板减少症和血小板减少性紫癜的治疗剂和预防剂以及易于因血小板减少症引起的出血的各种其它疾病的活性成分等。

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