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1. 发明授权

US11536713B2 Method for searching and screening for target of anti-cancer agent using non-human animal model having NOG established cancer cell line transplanted therein 有权
公开(公告)号：US11536713B2
公开(公告)日：2022-12-27
申请号：US13519059
申请日：2010-12-24
申请人： Masami Suzuki , Koichi Matsubara , Atsuhiko Kato , Chie Kato , Shinta Kobayashi , Yu Jau Chen , Masaki Yamazaki
发明人： Masami Suzuki , Koichi Matsubara , Atsuhiko Kato , Chie Kato , Shinta Kobayashi , Yu Jau Chen , Masaki Yamazaki
IPC分类号： G01N33/50 , A01K67/027
摘要： An objective of the present invention is to provide non-human animal models of cancer pathology, which mimic the hierarchical organization, cancer progression process, or biological property of human cancer tissues, and uses thereof. To achieve the objective described above, first, the present inventors transplanted cells of NOG-established cancer lines into NOG mice and morphologically observed the resulting tissue organization. As a result, the non-human animal models were demonstrated to exhibit pathologies (the hierarchical organization, cancer progression process, or biological properties of the cancer cells) similar to that of human cancer. Specifically, the present inventors succeeded in preparing non-human animal models exhibiting pathologies more similar to a human cancer, and cell culture systems using NOG-established cancer cell lines where the in vitro cell morphology is more similar to that of human cancer.

2. 发明授权

US08464681B2 Power unit for vehicle 有权
标题翻译：车辆动力单元
公开(公告)号：US08464681B2
公开(公告)日：2013-06-18
申请号：US12714184
申请日：2010-02-26
申请人： Kenji Matsuo , Masaki Yamazaki
发明人： Kenji Matsuo , Masaki Yamazaki
IPC分类号： F02N11/08
CPC分类号： B60K6/48 , B60L11/12 , B60Y2200/12 , F02N11/00 , F02N15/022 , Y02T10/6221 , Y10T74/19219 , Y10T74/20177
摘要： A vehicle power unit including a speed reducing gear train including a starter driven gear, a starting one-way clutch interposed between the starter driven gear and a crankshaft. The speed reducing gear train and the starting one-way clutch are provided between a starter motor and the crankshaft. A transmission includes gear trains for a plurality of gear speeds wherein the gear trains are provided between a main shaft and a counter shaft. A hybrid type configuration is possible wherein the starter motor produces power for driving the vehicle and to impart a drive assisting force. The starter motor can be changed over between a normal rotational operation and a reverse rotational operation. A power transmission idle gear is interposed between the starter driven gear and a power transmitting gear through a running one-way clutch for permitting power transmission to the side of the main shaft.
摘要翻译：一种车辆动力单元，包括包括起动器从动齿轮的减速齿轮系，以及置于起动器从动齿轮和曲轴之间的起动单向离合器。减速齿轮系和起动单向离合器设置在起动电动机和曲轴之间。变速器包括用于多个齿轮速度的齿轮系，其中齿轮系设置在主轴和副轴之间。混合型配置是可能的，其中起动马达产生用于驱动车辆的动力并赋予驱动辅助力。起动马达可以在正常旋转操作和反向旋转操作之间切换。动力传动空转齿轮通过运行中的单向离合器插入起动从动齿轮和动力传递齿轮之间，以允许动力传递到主轴侧。

3. 发明申请

US20090195240A1 Pickup coil having adjustable characteristic frequency 有权
标题翻译：拾音线圈具有可调特征频率
公开(公告)号：US20090195240A1
公开(公告)日：2009-08-06
申请号：US12319774
申请日：2009-01-12
申请人： Masaki Yamazaki
发明人： Masaki Yamazaki
IPC分类号： G01R33/02 , G01P3/48
CPC分类号： F02P7/0677
摘要： A pickup coil includes a sensing unit having an iron core, a permanent magnet magnetically coupled to a rear end position of the iron core, and a coil for sensing a change of magnetic flux occurring in the iron core; and a supporting frame member. The sensing unit is molded with a cup-shaped resin case. The sensing unit is integrally molded with the supporting frame member and is mounted on a mounting object via the supporting frame member. A plurality of weight units for adjusting a characteristic frequency of the coil is stored in a weight storage section formed inside the resin case at a position spaced away from the supporting frame member. The weight storage section is sized such that one or more weight units are accommodated therein.
摘要翻译：拾取线圈包括具有铁心的感测单元，与铁芯的后端位置磁耦合的永磁体，以及用于感测铁芯中产生的磁通变化的线圈; 和支撑框架构件。传感单元用杯形树脂盒模制。感测单元与支撑框架构件一体地模制并且经由支撑框架构件安装在安装对象上。用于调节线圈的特征频率的多个重量单元被存储在形成在树脂壳体内部的与支撑框架构件间隔开的位置处的重量存储部分中。重量存储部分的尺寸使得一个或多个重量单元被容纳在其中。

4. 发明申请

US20060187007A1 Electronic key system for vehicle, and vehicle 失效
公开(公告)号：US20060187007A1
公开(公告)日：2006-08-24
申请号：US11358579
申请日：2006-02-21
申请人： Takeshi Konno , Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Sho Yamamoto , Yusuke Funayose
发明人： Takeshi Konno , Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Sho Yamamoto , Yusuke Funayose
IPC分类号： B60R25/10 , G05B19/00
CPC分类号： B60R25/24 , B60R2325/306 , G07C9/00309 , G07C2209/62 , G07C2209/63
摘要： An electronic key system for a vehicle provides a warning corresponding to a traveling state if an occupant has dropped the electronic key while a vehicle is running. A control unit 14 of the vehicle outputs a request signal Sr to the electronic key 12 at transmission intervals T corresponding to the traveling state. An answer signal Sa caused by the request signal Sr from the electronic key 12 is detected. A warning lamp 68 is lit up at a point after the detection of the answer signal Sa stops. The transmission interval T of the request signal Sr is specified in a map 88 stored in the control unit 14, and is set short corresponding to the increase of the vehicle speed V, the acceleration/deceleration ‘a’, and the yaw rate Y.

5. 发明授权

US06966223B2 Vehicle speed display apparatus 有权
标题翻译：车速显示装置
公开(公告)号：US06966223B2
公开(公告)日：2005-11-22
申请号：US10753109
申请日：2004-01-07
申请人： Masaki Yamazaki , Takeshi Nakazawa
发明人： Masaki Yamazaki , Takeshi Nakazawa
IPC分类号： G01P3/42 , B60K31/18 , B60K35/00 , G01D7/08 , G01P1/04 , G01P1/07 , G01P3/00 , G01P21/00 , G01P21/02 , G06F9/00 , G11C7/00
CPC分类号： G01P1/07
摘要： A vehicle speed display apparatus capable of displaying an accurate vehicle speed in either 2WD mode or in 4WD mode. A vehicle speed calculating unit 51 calculates the vehicle speed, according to the output from a wheel rotational speed sensor 22. A 2WD/4WD detecting unit 52 switches the destination of the vehicle speed calculated by the vehicle speed-calculating unit 51 between a 2WD correcting unit 53 and a 4WD correcting unit 54, depending whether the vehicle is traveling in 2WD mode or in 4WD mode. The 2WD correcting unit 53 corrects the vehicle speed in the 2WD mode using a first correction coefficient for the 2WD mode, and the 4WD correcting unit 54 corrects the vehicle speed in the 4WD mode using a second correction coefficient for the 4WD mode. The corrected vehicle speed is displayed by a vehicle speed display unit 55.
摘要翻译：能够以2WD模式或4WD模式显示准确车速的车速显示装置。车速计算单元51根据车轮转速传感器22的输出计算车速.2WD / 4WD检测单元52将由车速计算单元51计算出的车速的目的地切换到2WD校正单元53和4WD校正单元54，这取决于车辆是以2WD模式还是以4WD模式行驶。 2WD校正单元53使用2WD模式的第一校正系数来校正2WD模式中的车速，并且4WD校正单元54使用用于4WD模式的第二校正系数来校正4WD模式中的车速。校正车速由车速显示单元55显示。

6. 发明授权

US08148975B2 Pickup coil for sensing rotary speed of engine, the coil including adjustable weight member 有权
标题翻译：用于检测发动机转速的拾取线圈，线圈包括可调重量构件
公开(公告)号：US08148975B2
公开(公告)日：2012-04-03
申请号：US12319774
申请日：2009-01-12
申请人： Masaki Yamazaki
发明人： Masaki Yamazaki
IPC分类号： G01B7/30
CPC分类号： F02P7/0677
摘要： A pickup coil includes a sensing unit having an iron core, a permanent magnet magnetically coupled to a rear end position of the iron core, and a coil for sensing a change of magnetic flux occurring in the iron core; and a supporting frame member. The sensing unit is molded with a cup-shaped resin case. The sensing unit is integrally molded with the supporting frame member and is mounted on a mounting object via the supporting frame member. A plurality of weight units for adjusting a characteristic frequency of the coil is stored in a weight storage section formed inside the resin case at a position spaced away from the supporting frame member. The weight storage section is sized such that one or more weight units are accommodated therein.
摘要翻译：拾取线圈包括具有铁心的感测单元，与铁芯的后端位置磁耦合的永磁体，以及用于感测铁芯中产生的磁通变化的线圈; 和支撑框架构件。传感单元用杯形树脂盒模制。感测单元与支撑框架构件一体地模制并且经由支撑框架构件安装在安装对象上。用于调节线圈的特征频率的多个重量单元被存储在形成在树脂壳体内部的与支撑框架构件间隔开的位置处的重量存储部分中。重量存储部分的尺寸使得一个或多个重量单元被容纳在其中。

7. 发明申请

US20110067367A1 AIR CLEANER APPARATUS 失效
标题翻译：空气清洁设备
公开(公告)号：US20110067367A1
公开(公告)日：2011-03-24
申请号：US12883998
申请日：2010-09-16
申请人： Sho YAMAMOTO , Shigeru Kodaira , Tatsuya Shiokawa , Masaki Yamazaki , Hiromitsu Shiina , Shun Fujitsu , Yukinori Kurakawa
发明人： Sho YAMAMOTO , Shigeru Kodaira , Tatsuya Shiokawa , Masaki Yamazaki , Hiromitsu Shiina , Shun Fujitsu , Yukinori Kurakawa
IPC分类号： B01D50/00
CPC分类号： F02M35/162
摘要： An air cleaner apparatus includes a lid that covers an opening formed in an air cleaner box is provided with an intake port communicating with the opening. In addition, a regulator is attached to an upper wall portion of the air cleaner box, the intake port is extended to the upper wall portion of the air cleaner box so as to cover the regulator, and the regulator is placed facing inside an intake passage connecting between the intake port and the opening. The air cleaner apparatus so configured provides a sufficient cooling effect, and is excellent in ease of maintenance.
摘要翻译：一种空气滤清器装置，包括覆盖空气滤清器箱形成的开口的盖，该盖设有与开口连通的进气口。此外，调节器附接到空气滤清器箱的上壁部分，进气口延伸到空气滤清器箱的上壁部分以覆盖调节器，并且调节器面向入口通道连接在进气口和开口之间。这样构成的空气滤清器装置具有足够的冷却效果，并且易于维护。

8. 发明申请

US20100229814A1 POWER UNIT FOR VEHICLE 有权
标题翻译：车辆动力单元
公开(公告)号：US20100229814A1
公开(公告)日：2010-09-16
申请号：US12714184
申请日：2010-02-26
申请人： Kenji Matsuo , Masaki Yamazaki
发明人： Kenji Matsuo , Masaki Yamazaki
IPC分类号： F02N11/08 , F16H59/04
CPC分类号： B60K6/48 , B60L11/12 , B60Y2200/12 , F02N11/00 , F02N15/022 , Y02T10/6221 , Y10T74/19219 , Y10T74/20177
摘要： A vehicle power unit including a speed reducing gear train including a starter driven gear, a starting one-way clutch interposed between the starter driven gear and a crankshaft. The speed reducing gear train and the starting one-way clutch are provided between a starter motor and the crankshaft. A transmission includes gear trains for a plurality of gear speeds wherein the gear trains are provided between a main shaft and a counter shaft. A hybrid type configuration is possible wherein the starter motor produces power for driving the vehicle and to impart a drive assisting force. The starter motor can be changed over between a normal rotational operation and a reverse rotational operation. A power transmission idle gear is interposed between the starter driven gear and a power transmitting gear through a running one-way clutch for permitting power transmission to the side of the main shaft.
摘要翻译：一种车辆动力单元，包括包括起动器从动齿轮的减速齿轮系，以及置于起动器从动齿轮和曲轴之间的起动单向离合器。减速齿轮系和起动单向离合器设置在起动电动机和曲轴之间。变速器包括用于多个齿轮速度的齿轮系，其中齿轮系设置在主轴和副轴之间。混合型配置是可能的，其中起动马达产生用于驱动车辆的动力并赋予驱动辅助力。起动马达可以在正常旋转操作和反向旋转操作之间切换。动力传动空转齿轮通过运行中的单向离合器插入起动从动齿轮和动力传递齿轮之间，以允许动力传递到主轴侧。

9. 发明授权

US07626494B2 Moving body, and electronic key system for moving body 失效
标题翻译：移动体，移动体电子钥匙系统
公开(公告)号：US07626494B2
公开(公告)日：2009-12-01
申请号：US11354504
申请日：2006-02-15
申请人： Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Takeshi Konno , Sho Yamamoto , Yusuke Funayose
发明人： Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Takeshi Konno , Sho Yamamoto , Yusuke Funayose
IPC分类号： B60Q1/00 , B60T8/32 , G06F19/00 , G06G7/70
CPC分类号： B60R25/04 , B60R25/241 , G07C9/00309 , G07C2009/00793 , G07C2209/04
摘要： An electronic key system 100 for a moving body, for example an all-terrain vehicle 10, includes an electronic key 11 and a control unit 50. The electronic key 11 transmits a control code Md stored in a ROM 76. The control unit 50 reads a speed limit Vs and a power limit Ws out of one of first to fourth control mode data Md1 to Md4, which corresponds to the received control code Md, and supplies the limits to a drive control performing section 104. The drive control performing section 104 controls an engine 22 in accordance with the speed limit Vs and the power limit Ws to limit a travel speed V and power W. This renders the driving performance appropriate to the driving condition and/or the driver.
摘要翻译：用于移动体，例如全地形车10的电子钥匙系统100包括电子钥匙11和控制单元50.电子钥匙11发送存储在ROM76中的控制代码Md。控制单元50读取与接收到的控制码Md对应的第一至第四控制模式数据Md1至Md4中的一个速度限制Vs和功率限制Ws，并将该限制提供给驱动控制执行部分104.驱动控制执行部分104 根据速度限制Vs和功率限制Ws控制发动机22，以限制行驶速度V和功率W.这使得驾驶性能适合于驾驶状况和/或驾驶员。

10. 发明申请

US20060181409A1 Moving body, and electronic key system for moving body 失效
标题翻译：移动体，移动体电子钥匙系统
公开(公告)号：US20060181409A1
公开(公告)日：2006-08-17
申请号：US11354504
申请日：2006-02-15
申请人： Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Takeshi Konno , Sho Yamamoto , Yusuke Funayose
发明人： Takao Yamamoto , Tomohiko Yashiro , Masaki Yamazaki , Takeshi Konno , Sho Yamamoto , Yusuke Funayose
IPC分类号： G08B1/00
CPC分类号： B60R25/04 , B60R25/241 , G07C9/00309 , G07C2009/00793 , G07C2209/04
摘要： An electronic key system 100 for a moving body, for example an all-terrain vehicle 10, includes an electronic key 11 and a control unit 50. The electronic key 11 transmits a control code Md stored in a ROM 76. The control unit 50 reads a speed limit Vs and a power limit Ws out of one of first to fourth control mode data Md1 to Md4, which corresponds to the received control code Md, and supplies the limits to a drive control performing section 104. The drive control performing section 104 controls an engine 22 in accordance with the speed limit Vs and the power limit Ws to limit a travel speed V and power W. This renders the driving performance appropriate to the driving condition and/or the driver.
摘要翻译：用于移动体，例如全地形车10的电子钥匙系统100包括电子钥匙11和控制单元50.电子钥匙11发送存储在ROM76中的控制代码Md。控制单元50读取与接收的控制码Md对应的第一至第四控制模式数据Md 1至Md 4中的一个速度限制Vs和功率限制Ws，并将该限制提供给驱动控制执行部件104.驱动控制执行部分104根据速度限制Vs和功率限制Ws来控制发动机22，以限制行驶速度V和功率W.这使驾驶性能适合驾驶状况和/或驾驶员。

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