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1. 发明授权

US08153467B2 Semiconductor device with groove structure to prevent molding resin overflow over a light receiving region of a photodiode during manufacture and method for manufacturing same 有权
标题翻译：具有凹槽结构的半导体器件，用于防止在制造期间模制树脂在光电二极管的光接收区域上溢出及其制造方法
公开(公告)号：US08153467B2
公开(公告)日：2012-04-10
申请号：US12398520
申请日：2009-03-05
申请人： Shuji Yoneda , Masato Oishi , Tamotsu Shinohara , Shinji Watanabe , Koji Miyata , Seiji Fukae , Kenji Yamauchi , Yoichi Goto , Masakazu Baba
发明人： Shuji Yoneda , Masato Oishi , Tamotsu Shinohara , Shinji Watanabe , Koji Miyata , Seiji Fukae , Kenji Yamauchi , Yoichi Goto , Masakazu Baba
IPC分类号： H01L21/00
CPC分类号： H01L31/0203 , H01L2224/32245 , H01L2224/48247 , H01L2224/49171 , H01L2224/73265 , H01L2924/1815 , H01L2924/3025 , H01L2224/48091 , H01L2924/00014 , H01L2924/00
摘要： A method for manufacturing a semiconductor device, includes the steps of: forming a resin layer on an upper surface of a substrate including a photodiode such that the resin layer does not cover a light receiving region of the photodiode; forming at least one groove in the resin layer so as to surround the light receiving region; and subsequently mold-sealing the photodiode by loading the substrate into a mold and filling the mold with a molding resin.
摘要翻译：一种制造半导体器件的方法，包括以下步骤：在包括光电二极管的基板的上表面上形成树脂层，使得树脂层不覆盖光电二极管的光接收区域; 在所述树脂层中形成至少一个凹槽以围绕所述光接收区域; 然后通过将基板加载到模具中并用模制树脂填充模具来模制密封光电二极管。

2. 发明授权

US07842514B2 Particle manipulation unit, chip and detection device having the same, mounted thereon, and methods of separating, capturing and detecting proteins 有权
标题翻译：其上安装有颗粒操作单元，芯片和检测装置，以及分离，捕获和检测蛋白质的方法
公开(公告)号：US07842514B2
公开(公告)日：2010-11-30
申请号：US10537292
申请日：2003-11-25
申请人： Wataru Hattori , Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
发明人： Wataru Hattori , Masakazu Baba , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
IPC分类号： G01N33/558
CPC分类号： B01D61/18 , B01D29/00 , B01D67/0062 , B01D69/00 , B01D71/02 , B01D71/027 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2400/086 , G01N33/5302
摘要： A channel (1) formed in a substrate (41) branches into channels (2, 3) at a branch point (43). On this branch point, obstacles (8) having a columnar structure are aligned at certain intervals.
摘要翻译：形成在基板（41）中的通道（1）在分支点（43）处分支成通道（2,3）。在该分支点上，具有柱状结构的障碍物（8）以一定间隔对准。

3. 发明授权

US07586091B2 Mass spectrometric system and mass spectrometry 失效
标题翻译：质谱系统和质谱
公开(公告)号：US07586091B2
公开(公告)日：2009-09-08
申请号：US10549587
申请日：2004-03-15
申请人： Katsutoshi Takahashi , Kazuhiro Iida , Masakazu Baba , Noriyuki Iguchi , Toru Sano , Hisao Kawaura , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
发明人： Katsutoshi Takahashi , Kazuhiro Iida , Masakazu Baba , Noriyuki Iguchi , Toru Sano , Hisao Kawaura , Toshitsugu Sakamoto , Wataru Hattori , Hiroko Someya
IPC分类号： H01J49/00
CPC分类号： H01J49/0418 , B01L3/502746 , B01L3/502753 , B01L2200/0663 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/16 , B01L2400/086 , G01N1/22 , G01N30/84 , G01N2030/8452
摘要： After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separated in the channel. The ionized fraction is detected by a mass spectrometry unit (363) and analyzed by an analytical result analyzing unit (371). The analytical result is stored in a memory (369) while associated with position information in a driver control unit (367) and information on laser beam irradiation condition in a laser control unit (373), and the analytical result is imaged by an imaging unit (375). The imaged analytical result is displayed on a display (377).
摘要翻译：在将样品预先分离成在微芯片（353）中形成的通道中的多个部件之后，通过激光振荡器（361）的激光束沿着分离方向照射通道，以顺序地电离通道中分离的每个部分。通过质谱分析单元（363）检测离子化分数，用分析结果分析单元（371）进行分析。分析结果与激光控制单元（373）中的驱动器控制单元（367）中的位置信息和激光束照射条件的信息相关联地存储在存储器（369）中，并且分析结果由成像单元（375）。成像分析结果显示在显示器上（377）。

4. 发明申请

US20090070045A1 DIAGNOSIS SUPPORTING SYSTEM 审中-公开
标题翻译：诊断支持系统
公开(公告)号：US20090070045A1
公开(公告)日：2009-03-12
申请号：US12263147
申请日：2008-10-31
申请人： Wataru HATTORI , Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
发明人： Wataru HATTORI , Toru Sano , Masakazu Baba , Kazuhiro Iida , Hisao Kawaura , Noriyuki Iguchi , Hiroko Someya
IPC分类号： G06F19/00 , G06F17/18
CPC分类号： G01N27/44717 , G16H10/60 , G16H15/00
摘要： A diagnosis supporting system (10) includes a diagnosis data obtaining unit (20) that obtains diagnosis data in which a movement parameter reflecting a movement speed of each component in separating a sample collected from a test subject into plural components with a chip (12) and a character of each component is in correspondence, a parameter storing unit (34) that stores the movement parameter of a characteristic component showing a state of suffering from a specific disease in correspondence with the disease, a relationship data storing unit (35) that stores relationship data showing a relationship between the character of the characteristic component and a possibility of suffering from a specific disease, a detecting unit (21) that detects the characteristic component from the diagnosis data based on the movement parameter of the characteristic component and the movement parameter of the diagnosis data by making reference to the parameter storing unit (34), and an inference processing unit (22) that infers the possibility that the test subject is suffering by making reference to the relationship data storing unit (35) based on the character of the detected characteristic component.
摘要翻译：诊断支持系统（10）包括诊断数据获取单元（20），该诊断数据获取单元（20）获取诊断数据，其中，用芯片（12）将反映从测试对象收集的样本的每个组件的移动速度反映成多个组件的移动参数，并且每个部件的字符相对应，存储与疾病相对应地显示出患有特定疾病的状态的特征部件的移动参数的参数存储部（34），关系数据存储部（35），其中，存储表示特征成分的特征与患有特定疾病的可能性之间的关系的关系数据，根据特征成分的移动参数和运动来检测来自诊断数据的特征成分的检测部（21）参考存储单元（34）的诊断数据的参数以及推断处理（22），其基于检测到的特征分量的特性，参考关系数据存储单元（35）推测测试对象遭受的可能性。

5. 发明授权

US07274016B2 Liquid switch, and microchip and mass-analyzing system using the same 失效
标题翻译：液体开关，微芯片和质量分析系统使用相同
公开(公告)号：US07274016B2
公开(公告)日：2007-09-25
申请号：US10537295
申请日：2003-12-02
申请人： Kazuhiro Iida , Masakazu Baba , Hisao Kawaura , Toru Sano , Noriyuki Iguchi , Hiroko Someya , Wataru Hattori , Minoru Asogawa
发明人： Kazuhiro Iida , Masakazu Baba , Hisao Kawaura , Toru Sano , Noriyuki Iguchi , Hiroko Someya , Wataru Hattori , Minoru Asogawa
IPC分类号： G01N21/69 , H01J49/00 , B01D59/44
CPC分类号： B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2400/0688 , G01N30/20 , H01J49/04 , Y10T137/4891
摘要： A liquid sample (104) introduced in a main flow passage (101) is held in a dam portion (105), and a trigger liquid (106) is filled in a trigger flow passage (102). In this state, the trigger liquid (106) is further introduced at desired timing into the trigger flow passage (102) so that the front end portion of the level of the trigger liquid (106) is advanced and the front end portion is brought to be into contact with the dam portion (105). This causes the liquid sample (104) to move to the right (downstream side) in the figure, resulting in the liquid sample (104) flowing out to the downstream side of the main flow passage (101). This means that the trigger liquid (106) provides priming to realize a liquid switch.
摘要翻译：引入到主流路（101）中的液体样品（104）保持在坝部（105）中，并且将触发液体（106）填充在触发流路（102）中。在这种状态下，触发液体（106）在所需的时刻被进一步引入到触发流路（102）中，使得触发液体（106）的高度的前端部分前进，前端部分与坝部（105）接触。这使得液体样品（104）移动到图中的右侧（下游侧），导致液体样品（104）流出到主流动通道（101）的下游侧。这意味着触发液体（106）提供启动以实现液体开关。

6. 发明申请

US20060063273A1 Separating apparatus, separating method, and mass analyzing system 审中-公开
标题翻译：分离装置，分离方法和质量分析系统
公开(公告)号：US20060063273A1
公开(公告)日：2006-03-23
申请号：US10536908
申请日：2003-12-01
申请人： Minoru Asogawa , Masakazu Baba , Hisao Kawaura , Toru Sano , Kazuhiro Iida , Noriyuki Iguchi , Hiroko Someya
发明人： Minoru Asogawa , Masakazu Baba , Hisao Kawaura , Toru Sano , Kazuhiro Iida , Noriyuki Iguchi , Hiroko Someya
IPC分类号： G01N1/10
CPC分类号： G01N30/72 , Y10T436/2575
摘要： Individual components are separated with a high concentration and accurately, from a sample containing components-to-be-separated. The separation apparatus includes a channel through which a sample containing components-to-be-separated moves; and gateway portions partitioning the separation channel into a plurality of compartments. The separation apparatus further includes an external force imposing unit, which imposes external force to the components-to-be-separated so as to allow them to move through the channel. The external force imposing unit is configured so as to alternately repeatedly execute a first external force imposing pattern by which the external force is imposed in the forward direction of the channel, and a second external force imposing pattern by which the external force is imposed in the direction opposite to the forward direction along the channel. This makes it possible to fractionate the components-to-be-separated into any of the compartments.
摘要翻译：从含有待分离成分的样品中分离高浓度和准确的各组分。分离装置包括通道，通过该通道将含有要分离的成分的样品移动; 以及将分离通道分隔成多个隔室的通道部分。分离装置还包括外力施加单元，其向待分离的部件施加外力，以允许它们移动通过通道。外力施加单元被配置为交替地重复地执行第一外力施加模式，外力施加在通道的向前方向上，第二外力施加模式，外力施加在通道中方向与通道的向前方向相反。这使得可以将要分离的组分分馏成任何隔室。

7. 发明申请

US20060032071A1 Sample drying device as well as mass spectrometer and mass spectrometry system therewith 审中-公开
标题翻译：样品干燥装置以及质谱仪和质谱系统
公开(公告)号：US20060032071A1
公开(公告)日：2006-02-16
申请号：US10536767
申请日：2003-11-28
申请人： Masakazu Baba , Toru Sano , Kazuhiro Uda , Hisao Kawaura , Noriyuki Iguchi , Wataru Hattori , Hiroko Someya , Minoru Asogawa
发明人： Masakazu Baba , Toru Sano , Kazuhiro Uda , Hisao Kawaura , Noriyuki Iguchi , Wataru Hattori , Hiroko Someya , Minoru Asogawa
IPC分类号： F26B19/00
CPC分类号： H01J49/04 , G01N1/40
摘要： A channel (103) is formed in a substrate (101) and a drying area (107) comprising a plurality of pillars (105) is formed in one end of the channel (103). A cover (109) is formed over the channel (103), except the area above the drying area (107). When a sample is introduced into the channel (103), it is guided to the drying area (107) by capillary phenomenon. The drying area (107) is heated by a heater (111) to evaporate the solvent for concentrating and drying the solute.
摘要翻译：在衬底（101）中形成通道（103），并且在通道（103）的一端形成包括多个柱（105）的干燥区域（107）。除了干燥区域（107）上方的区域之外，在通道（103）上方形成有盖（109）。当样品被引入通道（103）时，通过毛细管现象被引导到干燥区域（107）。干燥区域（107）被加热器（111）加热以蒸发溶剂以浓缩和干燥溶质。

8. 发明授权

US06331238B1 Method of patterning a substrate with an atomic mask 失效
标题翻译：原子掩模和用原子掩模图案化衬底的方法
公开(公告)号：US06331238B1
公开(公告)日：2001-12-18
申请号：US09602061
申请日：2000-06-23
申请人： Takashi Yokoyama , Masakazu Baba
发明人： Takashi Yokoyama , Masakazu Baba
IPC分类号： C25D502
CPC分类号： B32B27/20 , Y10T428/24917 , Y10T428/24926 , Y10T428/265 , Y10T428/31678
摘要： There is provided a method of patterning a substrate with an atomic mask having a mask substrate and first atoms adsorbed on the mask substrate, the first atoms forming a mask pattern having a one-atomic thickness, including the steps, in sequence, of (a) depositing adatoms over a surface of a substrate to be patterned, the adatoms having low reactivity with second atoms of which the substrate is composed, and (b) putting the atomic mask close to the substrate in such a distance that the first atoms make a chemical bond with the adatoms, so that adatoms located nearest to the first atoms are desorbed out of the substrate to form a pattern on the substrate, the pattern being defined as an area where none of the adatoms exists. In accordance with the above mentioned method, it is possible to form a pattern on the sub-nanometer or nanometer order with high accuracy and in a short period of time, and it is also possible to repeatedly form the same pattern by using the atomic mask.
摘要翻译：提供了一种利用具有掩模衬底的原子掩模和吸附在掩模衬底上的第一原子的原子掩模图案化衬底的方法，第一原子形成具有一个原子厚度的掩模图案，其包括以下步骤：（a ）在待图案化的衬底的表面上沉积吸附原子，所述原子与所述衬底的第二原子具有低反应性，和（b）将所述原子掩模放置在所述衬底附近，使得所述第一原子形成与吸附原子的化学键，使得位于最靠近第一原子的吸附原子从衬底中解吸出来，以在衬底上形成图案，该图案被定义为不存在吸收原子的区域。根据上述方法，可以以高精度和短时间在亚纳米或纳米级上形成图案，并且还可以通过使用原子掩模重复形成相同的图案。

9. 发明授权

US07785533B2 Chip, device using the chip, and method of using the same 失效
标题翻译：使用芯片的芯片，器件及其使用方法
公开(公告)号：US07785533B2
公开(公告)日：2010-08-31
申请号：US10571585
申请日：2004-09-13
申请人： Machiko Fujita , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Wataru Hattori , Masakazu Baba , Noriyuki Iguchi
发明人： Machiko Fujita , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Wataru Hattori , Masakazu Baba , Noriyuki Iguchi
IPC分类号： G01N21/01
CPC分类号： B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L2200/0689 , B01L2200/141 , B01L2300/041 , B01L2300/0816 , B82Y30/00 , B82Y35/00 , G01N27/44791
摘要： A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).
摘要翻译：形成在芯片上的通道打开而不污染通道的内容物。设置在基板（103）上的通道（107a）和（107b）通过将由树脂层（102）和板状盖（101）构成的盖（113）压在基板（103）的表面上而被覆盖，。定影装置具有保持片（112）的板状盖（101），放置有基板（103）的基板（108）和螺钉（106））的保持板（104）。当覆盖通道（107a）和（107b）时，螺钉（106）被紧固并且盖（113）被压到基板（103）上以被固定。并且，当打开通道（107a）和（107b）的上部时，螺杆（106）向上转动并释放压力，并且从基板（103）的上部移除盖（113）。

10. 发明申请

US20070048179A1 Chip, device using the chip, and method of using the same 失效
标题翻译：使用芯片的芯片，器件及其使用方法
公开(公告)号：US20070048179A1
公开(公告)日：2007-03-01
申请号：US10571585
申请日：2004-09-13
申请人： Machiko Fujita , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Wataru Hattori , Masakazu Baba , Noriyuki Iguchi
发明人： Machiko Fujita , Toru Sano , Kazuhiro Iida , Hisao Kawaura , Wataru Hattori , Masakazu Baba , Noriyuki Iguchi
IPC分类号： G01N31/22
CPC分类号： B01L3/502707 , B01L3/502715 , B01L3/502746 , B01L2200/0689 , B01L2200/141 , B01L2300/041 , B01L2300/0816 , B82Y30/00 , B82Y35/00 , G01N27/44791
摘要： A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).
摘要翻译：形成在芯片上的通道打开而不污染通道的内容物。设置在基板（103）上的通道（107a）和（107b）通过将由树脂层（102）和板状盖（101）构成的盖（113）压到基板的表面 103）。定影装置具有保持片（112）的板状盖（101），放置有基板（103）的基板（108）和螺钉（106））的保持板（104）。当覆盖通道（107a）和（107b）时，螺钉（106）被紧固并且盖（113）被压到基板（103）上以被固定。并且，当打开通道（107a）和（107b）的上部时，螺杆（106）向上转动并释放压力，并且将盖（113）从基板的上部移除（ 103）。

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