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1. 发明授权

US07438392B2 Microfluidic substrates having improved fluidic channels 有权
标题翻译：具有改进的流体通道的微流体基底
公开(公告)号：US07438392B2
公开(公告)日：2008-10-21
申请号：US11281090
申请日：2005-11-17
申请人： Karthik Vaideeswaran , Andrew L. McNees , John W. Krawczyk , James M. Mrvos , Mark L. Doerre , Jason T. Vanderpool , Girish S. Patil , Richard L. Warner
发明人： Karthik Vaideeswaran , Andrew L. McNees , John W. Krawczyk , James M. Mrvos , Mark L. Doerre , Jason T. Vanderpool , Girish S. Patil , Richard L. Warner
IPC分类号： B41J2/05
CPC分类号： B41J2/1632 , B41J2/14145 , B41J2/1603 , B41J2/1623 , B41J2/1628 , B41J2/1631 , B41J2/1645 , B41J2/1646
摘要： A method for improving fluidic flow for a microfluidic device having a through hole or slot therein. The method includes the steps of forming one or more openings through at least part of a thickness of a substrate from a first surface to an opposite second surface using a reactive ion etching process whereby an etch stop layer is applied to side wall surfaces in the one or more openings during alternating etching and passivating steps as the openings are etched through at least a portion of the substrate. Substantially all of the etch stop layer coating is removed from the side wall surfaces by treating the side wall surfaces using a method selected from chemical treatment and mechanical treatment, whereby a surface energy of the treated side wall surfaces is increased relative to a surface energy of the side wall surfaces containing the etch stop layer coating.
摘要翻译：一种用于改善其中具有通孔或槽的微流体装置的流体流动的方法。该方法包括以下步骤：使用反应离子蚀刻工艺从基板的第一表面至相对的第二表面形成穿过衬底的至少一部分厚度的一个或多个开口，由此将蚀刻停止层施加到一个侧壁表面或者在交替蚀刻和钝化步骤期间，当开口被蚀刻通过衬底的至少一部分时，可以有更多的开口。通过使用选自化学处理和机械处理的方法处理侧壁表面，从侧壁表面去除基本上所有的蚀刻停止层涂层，由此所处理的侧壁表面的表面能相对于所述侧壁表面包含所述蚀刻停止层涂层。

2. 发明授权

US07041226B2 Methods for improving flow through fluidic channels 有权
标题翻译：改善通过流体通道流动的方法
公开(公告)号：US07041226B2
公开(公告)日：2006-05-09
申请号：US10701225
申请日：2003-11-04
申请人： Karthik Vaideeswaran , Andrew L. McNees , John W. Krawczyk , James M. Mrvos , Cory N. Hammond , Mark L. Doerre , Jason T. Vanderpool , Girish S. Patil , Christopher J. Money , Gary R. Williams , Richard L. Warner
发明人： Karthik Vaideeswaran , Andrew L. McNees , John W. Krawczyk , James M. Mrvos , Cory N. Hammond , Mark L. Doerre , Jason T. Vanderpool , Girish S. Patil , Christopher J. Money , Gary R. Williams , Richard L. Warner
IPC分类号： G01D15/00 , H01L21/00
CPC分类号： B41J2/1632 , B41J2/14145 , B41J2/1603 , B41J2/1623 , B41J2/1628 , B41J2/1631 , B41J2/1645 , B41J2/1646
摘要： A method for improving fluidic flow for a microfluidic device having a through hole or slot therein. The method includes the steps of forming one or more openings through at least part of a thickness of a substrate from a first surface to an opposite second surface using a reactive ion etching process whereby an etch stop layer is applied to side wall surfaces in the one or more openings during alternating etching and passivating steps as the openings are etched through at least a portion of the substrate. Substantially all of the etch stop layer coating is removed from the side wall surfaces by treating the side wall surfaces using a method selected from chemical treatment and mechanical treatment, whereby a surface energy of the treated side wall surfaces is increased relative to a surface energy of the side wall surfaces containing the etch stop layer coating.
摘要翻译：一种用于改善其中具有通孔或槽的微流体装置的流体流动的方法。该方法包括以下步骤：使用反应离子蚀刻工艺从基板的第一表面至相对的第二表面形成穿过衬底的至少一部分厚度的一个或多个开口，由此将蚀刻停止层施加到一个侧壁表面或者在交替蚀刻和钝化步骤期间，当开口被蚀刻通过衬底的至少一部分时，可以有更多的开口。通过使用选自化学处理和机械处理的方法处理侧壁表面，从侧壁表面去除基本上所有的蚀刻停止层涂层，由此所处理的侧壁表面的表面能相对于所述侧壁表面包含所述蚀刻停止层涂层。

3. 发明授权

US5344424A Selectively retractable, disposable surgical knife 失效
标题翻译：选择性伸缩，一次性手术刀
公开(公告)号：US5344424A
公开(公告)日：1994-09-06
申请号：US30758
申请日：1993-03-12
申请人： Philip L. Roberts , Mark L. Doerre
发明人： Philip L. Roberts , Mark L. Doerre
IPC分类号： A61B17/32
CPC分类号： A61B17/3213 , A61B2017/320084 , A61B2017/32113
摘要： A retractable, disposable surgical knife that includes a hollow sheath and a blade assembly received for sliding movement within the hollow sheath. The blade assembly includes a slide block and a knife blade held by the slide block. A mechanism including a cooperating resilient actuator and guide track allows the blade assembly to be selectively secured in a first, retracted position wherein the blade is withdrawn into the sheath and a second, extended position wherein the blade extends from the sheath for use. A separate mechanism is provided for permanently locking the blade assembly in a third, fully retracted position wherein blade is fully withdrawn within the sheath to prevent inadvertent sticks. The permanent locking mechanism is fully concealed within the sheath so as to prevent inadvertent engagement with an object and possible release from the permanently locked position.
摘要翻译：一种可伸缩的一次性手术刀，其包括中空护套和用于在中空护套内滑动运动的刀片组件。刀片组件包括滑动块和由滑块保持的刀片。包括配合的弹性致动器和引导轨道的机构允许刀片组件选择性地固定在第一缩回位置，其中刀片被撤回到护套中，并且第二延伸位置，其中刀片从护套延伸使用。提供了一种单独的机构，用于将叶片组件永久地锁定在第三完全缩回的位置，其中叶片在护套内被完全拉出以防止无意的棍子。永久性锁定机构完全隐藏在护套内，以防止与物体意外接合并可能从永久锁定位置释放。

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