专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20190076844A1 MODULAR MOBILE FIELD-DEPLOYABLE LABORATORY FOR RAPID, ON-SITE DETECTION AND ANALYSIS OF BIOLOGICAL TARGETS 审中-公开
公开(公告)号：US20190076844A1
公开(公告)日：2019-03-14
申请号：US16185178
申请日：2018-11-09
申请人： MRIGlobal
发明人： Jonathan L. Jacobs , Joseph A. Russell , Jacob R. Aspinwall
IPC分类号： B01L9/02 , C12Q1/686 , A45F4/02
摘要： A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

2. 发明申请

US20210116430A1 CHEMICAL AGENT DETECTOR WITH 30 SECOND CYCLE 有权
公开(公告)号：US20210116430A1
公开(公告)日：2021-04-22
申请号：US17072714
申请日：2020-10-16
申请人： MRIGlobal
发明人： Eric Peters , Louis Anderson , Charmel Grisham , Sara Paalhar , Sylvanna Couch
IPC分类号： G01N30/74 , G01N30/54 , G01N30/06
摘要： A gas chromatography instrument is provided that is capable of analyzing samples both quickly and accurately. The detector includes a first unit and a second unit that alternate between collection mode and desorption mode. This allows one unit to collect the sample, while the other unit desorbs another sample before the units switch operations. The alternating collection and desorption modes allows the detector to generate a data point approximately every thirty seconds, with each alternating unit.

3. 发明申请

US20150059580A1 FORENSIC AIR AND SURFACE SAMPLER TECHNOLOGY (FASST) COLLECTOR 审中-公开
标题翻译：审判空气和表面采样技术（FASST）收集器
公开(公告)号：US20150059580A1
公开(公告)日：2015-03-05
申请号：US14121380
申请日：2014-08-26
申请人： MRIGlobal
发明人： Joseph W. Clement , Peter J. Anderson , Micah R. Decker , Thomas J. Keeley , Mary E. Pierce , Valorie T. Ryan , Darren J. Radke
IPC分类号： B03C3/68 , B03C3/38
CPC分类号： B03C3/68 , B03C3/145 , B03C3/32 , B03C3/363 , B03C3/368 , B03C3/41 , B03C3/49 , B03C3/82 , B03C2201/04 , B03C2201/26
摘要： A particle collector for collecting biological material using electrostatic precipitator (ESP) technology including a removable ESP collection tube having an electrode wire suspended therein, a high voltage power supply coupled to the electrode wire for generating an ionization field within the collection tube causing smaller particles entering the collection tube to precipitate onto the walls of the collection tube, electronics including a microcontroller for controlling the operation of the collector, and a housing assembly for housing the collection tube, the high voltage power supply and the electronics. Some embodiments include an interlock system for disabling high voltage to the electrode wire if certain system parameters are not met, a static discharge mechanism for dissipating excess electrostatic charge which may accumulate on the collection tube during operation, and an altitude adjustment mechanism for adjusting the amount of high voltage supplied to the electrode wire based upon the altitude at which the collector is being used. A portable hand-held embodiment of the particle collector is also disclosed.
摘要翻译：一种用于使用静电除尘器（ESP）技术收集生物材料的颗粒收集器，其包括具有悬挂在其中的电极丝的可移除的ESP收集管，耦合到所述电极丝的高压电源，用于在所述收集管内产生电离场，导致较小的颗粒进入所述收集管沉淀到所述收集管的壁上，所述电子器件包括用于控制所述收集器的操作的微控制器，以及用于容纳所述收集管，所述高压电源和所述电子器件的壳体组件。一些实施例包括用于在不满足某些系统参数的情况下禁止对电极线的高电压的互锁系统，用于消除在运行期间可能积聚在收集管上的过量静电荷的静电放电机构和用于调节量的高度调节机构基于收集器被使用的高度提供给电极线的高电压。还公开了颗粒收集器的便携式手持实施例。

4. 发明申请

US20220331806A1 MODULAR MOBILE FIELD-DEPLOYABLE LABORATORY FOR RAPID, ON-SITE DETECTION AND ANALYSIS OF BIOLOGICAL TARGETS 有权
公开(公告)号：US20220331806A1
公开(公告)日：2022-10-20
申请号：US17808563
申请日：2022-06-24
申请人： MRIGlobal
发明人： Jonathan L. Jacobs , Joseph A. Russell , Jacob R. Aspinwall
IPC分类号： B01L9/02 , C12Q1/686 , A45F4/02 , A45F3/04 , A45C5/04 , B01L1/00 , A45C5/14 , A45C7/00
摘要： A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

5. 发明授权

US10913709B2 STAT3 inhibitor formulation 有权
公开(公告)号：US10913709B2
公开(公告)日：2021-02-09
申请号：US16603110
申请日：2018-04-05
申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services , GLG Pharma, LLC , MRIGLobal
发明人： Robert H. Shoemaker , Michael W. Lovell , Jonathan M. White , Shanker Gupta
IPC分类号： C07C309/73 , A61P35/00 , C07C215/10 , A61K9/00 , A61K9/08
摘要： Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.

6. 发明申请

US20180193843A1 MODULAR MOBILE FIELD-DEPLOYABLE LABORATORY FOR THE DETECTION, SEQUENCING AND ANALYSIS OF EMERGING INFECTIOUS DISEASES 审中-公开
公开(公告)号：US20180193843A1
公开(公告)日：2018-07-12
申请号：US15866073
申请日：2018-01-09
申请人： MRIGlobal
发明人： Jonathan L. Jacobs , Joseph A. Russell , Jacob R. Aspinwall
IPC分类号： B01L9/02 , C12Q1/04 , B01L7/00 , C12M1/00 , B01L3/00 , C12Q1/24 , G01N15/04 , G01N21/64 , G01N33/483 , G01N33/50 , G01N1/00 , G01N15/00
CPC分类号： B01L9/02 , A45C11/20 , A45C15/00 , A45F3/04 , A45F4/02 , B01L1/52 , B01L3/0275 , B01L3/502 , B01L3/5082 , B01L7/52 , B01L9/06 , B01L9/543 , B01L2200/028 , B01L2200/16 , B01L2200/18 , B01L2300/046 , B01L2300/0636 , B01L2300/0645 , B01L2300/0877 , B01L2300/18 , B01L2400/0424 , B01L2400/0487 , C12M41/14 , C12Q1/04 , C12Q1/24 , G01N15/04 , G01N21/6428 , G01N33/483 , G01N33/50 , G01N35/00871 , G01N2001/002 , G01N2015/0019 , G01N2015/0065 , G01N2035/00178 , G01N2035/00326 , G01N2035/00881 , G01N2800/00 , G01N2800/26
摘要： A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The mobile laboratory can be configured either in a single backpack configuration or in a footlocker configuration wherein both configurations include a plurality of different compartments specifically configured for holding all of the necessary equipment for successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source, a cold storage compartment for frozen and chilled critical reagents, a PCR detection system, a DNA/RNA sequencing system, a bioinformatics analysis system, a centrifuge, and a deployable workbench area which provides a stable workstation when either the backpack or footlocker configuration is deployed.

7. 发明授权

US09051558B2 Method for immune cell-assisted bacterial culturing 有权
标题翻译：免疫细胞辅助细菌培养方法
公开(公告)号：US09051558B2
公开(公告)日：2015-06-09
申请号：US13972888
申请日：2013-08-21
申请人： MRIGlobal
发明人： Kelly Brown , Richard Winegar , Jacqueline Bortzner , Nicole Moritz , Stephanie Sorrell
IPC分类号： C12N1/00 , C12N1/12 , C12N1/20 , C12Q1/04
CPC分类号： C12N1/20 , C12Q1/04 , Y02A50/57
摘要： A method of culturing fastidious bacteria where a conditioned cell culture medium is prepared in which eukaryotic cells have been cultured, but where the medium is substantially free of the cultured cells. Fastidious bacteria are cultured in the medium. The conditioned cell culture medium can contain secreted factors from the cells. These factors promote the growth of the fastidious bacteria. The fastidious bacterial culture is maintained for a time period sufficient for the fastidious bacteria to multiply. The fastidious bacteria are analyzed using PCR, DNA sequencing or microbiology characterization.
摘要翻译：培养细菌的方法，其中制备了已培养真核细胞但培养基基本上不含培养细胞的条件细胞培养基。在培养基中培养繁殖细菌。条件细胞培养基可以含有细胞分泌的因子。这些因素促进了细菌的生长。将细菌培养物保持一段足以使繁殖细菌繁殖的时间。使用PCR，DNA测序或微生物学表征来分析繁殖细菌。

8. 发明申请

US20140057272A1 METHOD FOR IMMUNE CELL-ASSISTED BACTERIAL CULTURING 有权
标题翻译：免疫细胞辅助细菌培养方法
公开(公告)号：US20140057272A1
公开(公告)日：2014-02-27
申请号：US13972888
申请日：2013-08-21
申请人： MRIGlobal
发明人： Kelly Brown , Richard Winegar , Jacqueline Bortzner , Nicole Moritz , Stephanie Sorrell
IPC分类号： C12N1/20 , C12Q1/04
CPC分类号： C12N1/20 , C12Q1/04 , Y02A50/57
摘要： A method of culturing fastidious bacteria where a conditioned cell culture medium is prepared in which eukaryotic cells have been cultured, but where the medium is substantially free of the cultured cells. Fastidious bacteria are cultured in the medium. The conditioned cell culture medium can contain secreted factors from the cells. These factors promote the growth of the fastidious bacteria. The fastidious bacterial culture is maintained for a time period sufficient for the fastidious bacteria to multiply. The fastidious bacteria are analyzed using PCR, DNA sequencing or microbiology characterization.
摘要翻译：培养细菌的方法，其中制备了已培养真核细胞但培养基基本上不含培养细胞的条件细胞培养基。在培养基中培养繁殖细菌。条件细胞培养基可以含有细胞分泌的因子。这些因素促进了细菌的生长。将细菌培养物保持一段足以使繁殖细菌繁殖的时间。使用PCR，DNA测序或微生物学表征来分析繁殖细菌。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式