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1. 发明授权

US08676383B2 Device for carrying out chemical or biological reactions 有权
标题翻译：用于进行化学或生物反应的装置
公开(公告)号：US08676383B2
公开(公告)日：2014-03-18
申请号：US11850345
申请日：2007-09-05
申请人： Lim Hi Tan , Jew Kwee Ngui , Hon Siu Shin , Ui Leng Soh , Yang Hooi Kee , Hock Lai Khoo , Mark T. Reed , Ching Ong Lau , Wolfgang Heimberg
发明人： Lim Hi Tan , Jew Kwee Ngui , Hon Siu Shin , Ui Leng Soh , Yang Hooi Kee , Hock Lai Khoo , Mark T. Reed , Ching Ong Lau , Wolfgang Heimberg
IPC分类号： G05B21/00
CPC分类号： B01L7/52 , B01L3/50855 , B01L7/54 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , B01L2300/1827 , B01L2300/1855 , C12Q1/686 , G01N21/6452
摘要： The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures. Because the reaction vessel receiving element is suitable for receiving standard microtiter plates, the device according to the invention may be integrated in existing process sequences.
摘要翻译：本发明涉及一种用于与反应容器接收元件进行化学或生物反应的装置，用于接收具有几个反应容器的微量滴定板，其中反应容器接收元件具有以规则图案排列以容纳相应的反应容器，用于加热反应容器接收元件的加热装置和用于冷却反应容器的冷却装置。本发明的特征在于将反应容器接收元件分成几段。各个片段彼此热分离，并且每个片段被分配加热装置，其可以独立于其它片段致动。通过反应容器接收元件的分割，可以将区域设定并保持在不同的温度。因为反应容器接收元件适于接收标准微量滴定板，所以根据本发明的装置可以集成在现有的工艺顺序中。

2. 发明申请

US20090203120A1 Thermal Cycling Apparatus and Method for Providing Thermal Uniformity 审中-公开
标题翻译：热循环装置和提供热均匀性的方法
公开(公告)号：US20090203120A1
公开(公告)日：2009-08-13
申请号：US12421568
申请日：2009-04-09
申请人： Hon Siu Shin , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
发明人： Hon Siu Shin , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
IPC分类号： C12M1/00
CPC分类号： B01L7/52 , B01L2300/0829 , B01L2300/1822
摘要： An apparatus and method for rapid thermal cycling including a thermal diffusivity plate. The thermal diffusivity plate can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling by a thermoelectric module. An edge heater can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling.
摘要翻译：一种用于快速热循环的装置和方法，包括热扩散板。热扩散板可以通过热电模块的热循环期间在整个热块组件中提供显着的温度均匀性。边缘加热器可以在热循环期间在整个热块组件中提供显着的温度均匀性。

3. 发明申请

US20080274511A1 DEVICE FOR CARRYING OUT CHEMICAL OR BIOLOGICAL REACTIONS 有权
标题翻译：执行化学或生物反应的装置
公开(公告)号：US20080274511A1
公开(公告)日：2008-11-06
申请号：US11850345
申请日：2007-09-05
申请人： Lim Hi TAN , Jew Kween Ngui , Hon Siu Shin , Ui Leng Soh , Yang Hooi Kee , Hock Lai Khoo , Mark T. Reed , Ching Ong Lau , Wolfgang Heimberg
发明人： Lim Hi TAN , Jew Kween Ngui , Hon Siu Shin , Ui Leng Soh , Yang Hooi Kee , Hock Lai Khoo , Mark T. Reed , Ching Ong Lau , Wolfgang Heimberg
IPC分类号： C12P19/34 , C12M1/02 , C12M1/34
CPC分类号： B01L7/52 , B01L3/50855 , B01L7/54 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , B01L2300/1827 , B01L2300/1855 , C12Q1/686 , G01N21/6452
摘要： The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures. Because the reaction vessel receiving element is suitable for receiving standard microtiter plates, the device according to the invention may be integrated in existing process sequences.
摘要翻译：本发明涉及一种用于与反应容器接收元件进行化学或生物反应的装置，用于接收具有几个反应容器的微量滴定板，其中反应容器接收元件具有以规则图案排列以容纳相应的反应容器，用于加热反应容器接收元件的加热装置和用于冷却反应容器的冷却装置。本发明的特征在于将反应容器接收元件分成几段。各个片段彼此热分离，并且每个片段被分配加热装置，其可以独立于其它片段致动。通过反应容器接收元件的分割，可以将区域设定并保持在不同的温度。因为反应容器接收元件适于接收标准微量滴定板，所以根据本发明的装置可以集成在现有的工艺顺序中。

4. 发明授权

US08859271B2 Thermal cycling apparatus and method for providing thermal uniformity 有权
标题翻译：热循环装置和提供热均匀性的方法
公开(公告)号：US08859271B2
公开(公告)日：2014-10-14
申请号：US13029085
申请日：2011-02-16
申请人： Hon Siu Shin , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
发明人： Hon Siu Shin , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
IPC分类号： C12M1/00 , C12M3/00 , B01L7/00
CPC分类号： B01L7/52 , B01L2300/0829 , B01L2300/1822
摘要： An apparatus and method for rapid thermal cycling including a thermal diffusivity plate. The thermal diffusivity plate can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling by a thermoelectric module. An edge heater can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling.
摘要翻译：一种用于快速热循环的装置和方法，包括热扩散板。热扩散板可以通过热电模块的热循环期间在整个热块组件中提供显着的温度均匀性。边缘加热器可以在热循环期间在整个热块组件中提供显着的温度均匀性。

5. 发明申请

US20110136219A1 THERMAL CYCLING APPARATUS AND METHOD FOR PROVIDING THERMAL UNIFORMITY 有权
标题翻译：热循环装置和提供热均匀性的方法
公开(公告)号：US20110136219A1
公开(公告)日：2011-06-09
申请号：US13029085
申请日：2011-02-16
申请人： Hon Siu SHIN , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
发明人： Hon Siu SHIN , Jew Kwee Ngui , Chee Kiong Lim , Ching Ong Lau , Lim Hi Tan , Yang Hooi Kee
IPC分类号： C12M1/00
CPC分类号： B01L7/52 , B01L2300/0829 , B01L2300/1822
摘要： An apparatus and method for rapid thermal cycling including a thermal diffusivity plate. The thermal diffusivity plate can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling by a thermoelectric module. An edge heater can provide substantial temperature uniformity throughout the thermal block assembly during thermal cycling.
摘要翻译：一种用于快速热循环的装置和方法，包括热扩散板。热扩散板可以通过热电模块的热循环期间在整个热块组件中提供显着的温度均匀性。边缘加热器可以在热循环期间在整个热块组件中提供显着的温度均匀性。

6. 发明申请

US20070184548A1 Device for carrying out chemical or biological reactions 审中-公开
标题翻译：用于进行化学或生物反应的装置
公开(公告)号：US20070184548A1
公开(公告)日：2007-08-09
申请号：US11470463
申请日：2006-09-06
申请人： Lim Hi Tan , Jew Ngui , Hon Shin , Ui Soh , Yang Kee , Hook Khoo , Mark Reed , Wolfgang Heimberg
发明人： Lim Hi Tan , Jew Ngui , Hon Shin , Ui Soh , Yang Kee , Hook Khoo , Mark Reed , Wolfgang Heimberg
IPC分类号： C12M1/34 , C12P19/34
CPC分类号： B01L7/52 , B01L7/54 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , B01L2300/1827
摘要： The invention relates to a device for carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures. Because the reaction vessel receiving element is suitable for receiving standard microtiter plates, the device according to the invention may be integrated in existing process sequences.
摘要翻译：本发明涉及一种用于与反应容器接收元件进行化学或生物反应的装置，用于接收具有几个反应容器的微量滴定板，其中反应容器接收元件具有以规则图案排列以容纳相应的反应容器，用于加热反应容器接收元件的加热装置和用于冷却反应容器的冷却装置。本发明的特征在于将反应容器接收元件分成几段。各个片段彼此热分离，并且每个片段被分配加热装置，其可以独立于其它片段致动。通过反应容器接收元件的分割，可以将区域设定并保持在不同的温度。因为反应容器接收元件适于接收标准微量滴定板，所以根据本发明的装置可以集成在现有的工艺顺序中。

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