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    • 1. 发明授权
    • Terahertz radiating device based on semiconductor coupled quantum wells
    • 基于半导体耦合量子阱的太赫兹辐射装置
    • US07176498B2
    • 2007-02-13
    • US10743268
    • 2003-12-23
    • Boris LaikhtmanLeonid Shvartsman
    • Boris LaikhtmanLeonid Shvartsman
    • H01L27/15
    • B82Y20/00H01S5/34H01S5/3407H01S5/3425H01S2302/02
    • A semiconductor device and method of its fabrication are provided to enable the device operation in a THz spectral range. The device comprises a heterostructure including at least first and second semiconductor layers. The first and second layers are made of materials providing a quantum mechanical coupling between an electron quantum well (EQW) in the first layer and a hole quantum well (HQW) in the second layer, and providing an overlap between the valence band of the material of the second layer and the conduction band of the material of the first layer. A layout of the layers is selected so as to provide a predetermined dispersion of energy subbands in the conduction band of the first layer and the valence band of the second layer. An application of an external bias field across the first and second layers causes THz radiation originating from radiative transitions of non-equilibrium carriers between at least one of the following: neighboring energy subbands of the EQW, neighboring energy subbands of the HQW, and ground energy subbands of the EQW and HQW.
    • 提供了一种其制造的半导体器件及其制造方法,以使器件在THz光谱范围内工作。 该器件包括至少包括第一和第二半导体层的异质结构。 第一层和第二层由在第一层中的电子量子阱(EQW)和第二层中的空穴量子阱(HQW)之间提供量子力学耦合的材料制成,并且提供材料的价带之间的重叠 以及第一层材料的导带。 选择层的布局,以便在第一层的导带和第二层的价带中提供能量子带的预定色散。 跨越第一层和第二层的外部偏置场的应用导致源于非平衡载流子的辐射跃迁的THz辐射在以下至少一个之间:EQW的相邻能量子带,HQW的相邻能量子带和地面能量 EQW和HQW的子带。
    • 4. 发明申请
    • Methods and apparatus for non-invasive determination of patient's blood conditions
    • 用于非侵入性测定患者血液状况的方法和装置
    • US20070232940A1
    • 2007-10-04
    • US11604401
    • 2006-11-27
    • Ilya FineLeonid Shvartsman
    • Ilya FineLeonid Shvartsman
    • A61B5/02A61B6/00
    • A61B5/1455A61B5/0053A61B5/14535A61B5/14546A61B5/6826A61B5/6838
    • A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated. At least a portion of the measured data and stimulus related data are processed so as to determine a relation between a time function of the at least one stimulus ST(t) and a time function of the measured data OR(t). This relation is indicative of at least one blood circulation and blood coagulation related parameter of the mammal.
    • 提出了用于非侵入式确定哺乳动物血液凝固相关和血液循环相关参数的方法和装置。 至少一种刺激ST在哺乳动物的含血液培养基中非侵入性诱导预设的一段时间t ST。 选择至少一种刺激以引起以下至少一种:(a)诱导三种Virchow的三联元件中的至少两种,包括血流异常; 血液成分异常和血管壁异常,(b)引起红细胞(RBC)聚集或局部血液粘度变化。 在哺乳动物的测量位置通过在外部场施加预定时间段t m来非测量地进行测量,检测测量位置对所施加的场的响应,并且测量数据 产生指示。 处理测量数据和刺激相关数据的至少一部分,以便确定至少一个刺激ST(t)的时间函数与测量数据OR(t)的时间函数之间的关系。 该关系表示哺乳动物的至少一种血液循环和凝血相关参数。
    • 6. 发明申请
    • Methods and apparatus for non-invasive determination of patient's blood conditions
    • 用于非侵入性测定患者血液状况的方法和装置
    • US20110033385A1
    • 2011-02-10
    • US12835998
    • 2010-07-14
    • Ilya FineLeonid Shvartsman
    • Ilya FineLeonid Shvartsman
    • A61K49/00A61P43/00
    • A61B5/1455A61B5/0053A61B5/14535A61B5/14546A61B5/6826A61B5/6838
    • A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated. At least a portion of the measured data and stimulus related data are processed so as to determine a relation between a time function of the at least one stimulus ST(t) and a time function of the measured data OR(t). This relation is indicative of at least one blood circulation and blood coagulation related parameter of the mammal.
    • 提出了用于非侵入式确定哺乳动物血液凝固相关和血液循环相关参数的方法和装置。 至少一种刺激ST在哺乳动物的含血液培养基中非侵入性诱导预设时间tST。 选择至少一种刺激以引起以下至少一种:(a)诱导三种Virchow的三联元件中的至少两种,包括血流异常; 血液成分异常和血管壁异常,(b)引起红细胞(RBC)聚集或局部血液粘度变化。 在哺乳动物的测量位置通过在外部场施加预定的时间段tm而非侵入性地进行测量,检测测量位置对所施加的场的响应,并且产生表示其的测量数据。 处理测量数据和刺激相关数据的至少一部分,以便确定至少一个刺激ST(t)的时间函数与测量数据OR(t)的时间函数之间的关系。 该关系表示哺乳动物的至少一种血液循环和凝血相关参数。
    • 7. 发明授权
    • Methods and apparatus for non-invasive determination of patient's blood conditions
    • 用于非侵入性测定患者血液状况的方法和装置
    • US07758505B2
    • 2010-07-20
    • US11604401
    • 2006-11-27
    • Ilya FineLeonid Shvartsman
    • Ilya FineLeonid Shvartsman
    • A61B5/00
    • A61B5/1455A61B5/0053A61B5/14535A61B5/14546A61B5/6826A61B5/6838
    • A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated. At least a portion of the measured data and stimulus related data are processed so as to determine a relation between a time function of the at least one stimulus ST(t) and a time function of the measured data OR(t). This relation is indicative of at least one blood circulation and blood coagulation related parameter of the mammal.
    • 提出了用于非侵入式确定哺乳动物血液凝固相关和血液循环相关参数的方法和装置。 至少一种刺激ST在哺乳动物的含血液培养基中非侵入性诱导预设时间tST。 选择至少一种刺激以引起以下至少一种:(a)诱导三种Virchow的三联元件中的至少两种,包括血流异常; 血液成分异常和血管壁异常,(b)引起红细胞(RBC)聚集或局部血液粘度变化。 在哺乳动物的测量位置通过在外部场施加预定的时间段tm而非侵入性地进行测量,检测测量位置对所施加的场的响应,并且产生表示其的测量数据。 处理测量数据和刺激相关数据的至少一部分,以便确定至少一个刺激ST(t)的时间函数与测量数据OR(t)的时间函数之间的关系。 该关系表示哺乳动物的至少一种血液循环和凝血相关参数。
    • 10. 发明授权
    • Method for non-invasive optical measurements of blood parameters
    • 血液参数无创光学测量方法
    • US06587704B1
    • 2003-07-01
    • US09652350
    • 2000-08-31
    • Ilya FineLeonid Shvartsman
    • Ilya FineLeonid Shvartsman
    • A61B500
    • A61B5/0059G06F19/00
    • A non-invasive method of optical measurements is presented for determining at least one desired parameter of patient's blood. The method utilizes reference data indicative of the values of the desired blood parameter as a function of at least two measurable parameters. At least one of the measurable parameters is derived from scattering spectral features of the medium highly sensitive to patient individuality, and the at least one other measurable parameter is indicative of artificial kinetics of the optical characteristics of the patient's blood perfused fleshy medium. A condition of artificial kinetics is created at a measurement location, and maintained during a certain time. Measurements are carried out with different wavelengths of incident light during a time period including this certain time. Measured data is in the form of time evolutions of light responses of the medium corresponding to the different wavelengths. By analyzing the measured data, the at least two measurable parameters are extracted, and the reference data is utilized to determine the at least one desired blood parameter.
    • 提出了用于确定患者血液的至少一个期望参数的非侵入性光学测量方法。 该方法利用指示所需血液参数的值作为至少两个可测量参数的函数的参考数据。 可测量参数中的至少一个来自对患者个性高度敏感的介质的散射光谱特征,并且至少一个其他可测量参数表示患者血液灌注肉质培养基的光学特性的人为动力学。 在测量位置产生人造动力学条件,并在一定时间内保持。 在包括这一定时间的时间段内,用不同波长的入射光进行测量。 测量数据是对应于不同波长的介质的光响应的时间演变的形式。 通过分析测量数据,提取至少两个可测量参数,并且使用参考数据来确定至少一个期望的血液参数。