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1. 发明授权

US07535647B1 Beam splitters for, for instance, high efficiency spectral imagers 有权
标题翻译：光束分离器，例如高效光谱成像仪
公开(公告)号：US07535647B1
公开(公告)日：2009-05-19
申请号：US11803398
申请日：2007-05-11
申请人： Leonard John Otten, III , Gavin R. G. Erry
发明人： Leonard John Otten, III , Gavin R. G. Erry
IPC分类号： G02B27/14
CPC分类号： G02B27/1006 , G02B27/1086 , G02B27/144 , G02B27/145
摘要： Optical instruments having, inter alia, optics to process wavelengths of electromagnetic radiation to produce an interferogram. The instruments include an optical path and optical elements positioned along this path for splitting and recombining the wavelengths which interfere with each other to produce a plurality of different fringes of different wavelengths. The optics include matched gratings which are positioned along the optical path outside of the interferometer optics to produce first and second sets of spectrally dispersed beams. The interferometer optics includes a beam splitter and first and second mirrors. In two embodiments the beam splitter has an internal surface including three zones. The instruments can all include a detector for detecting the interferogram and means for processing the detected interferogram to produce spectral information that is spatially distributed.
摘要翻译：光学仪器尤其具有用于处理电磁辐射波长以产生干涉图的光学装置。仪器包括沿着该路径定位的光路和光学元件，用于分离和重组彼此干涉的波长，以产生多个不同波长的不同条纹。光学器件包括沿着干涉仪光学器件外部的光路定位的匹配光栅，以产生第一和第二组光谱分散的光束。干涉仪光学器件包括分束器和第一和第二反射镜。在两个实施例中，分束器具有包括三个区域的内表面。仪器都可以包括用于检测干涉图的检测器和用于处理检测到的干涉图以产生空间分布的光谱信息的装置。

2. 发明授权

US07232999B1 Laser wavefront characterization 有权
标题翻译：激光波前表征
公开(公告)号：US07232999B1
公开(公告)日：2007-06-19
申请号：US10903095
申请日：2004-07-30
申请人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
发明人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
IPC分类号： G01J5/00
CPC分类号： G01J9/00
摘要： The device and method of the present invention are useful for determining the characteristics of an infrared wavefront. The present invention involves positioning a beam of light containing the infrared wavefront to be characterized onto a distorted grating, using the grating to produce a plurality of images, determining the infrared wavefront from the plurality of images and analyzing the infrared wavefront for features that characterize the infrared wavefront.
摘要翻译：本发明的装置和方法可用于确定红外波前的特性。本发明涉及将包含要表征的红外波前的光束定位在失真的光栅上，使用光栅产生多个图像，从多个图像中确定红外波前，并分析红外波阵面的特征，红外波前。

3. 发明授权

US07104649B2 Wavefront characterization of corneas 有权
标题翻译：角膜的波前表征
公开(公告)号：US07104649B2
公开(公告)日：2006-09-12
申请号：US10115355
申请日：2002-04-02
申请人： Leonard John Otten, III , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
发明人： Leonard John Otten, III , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
IPC分类号： A61B3/10
CPC分类号： A61B3/1015 , A61B3/107 , A61F2/142 , G01J9/00
摘要： Apparatus for determining if a cornea (whether in vitro or in vivo) has been modified (either surgically or otherwise). The method includes the steps of: passing a beam of collimated light a (either coherent or incoherent) through the cornea to produce a distorted wavefront; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification. The analysis of the distorted wavefront can be for the presence of higher order aberrations, or Gausian characteristics which are indicative of modifications. More particularly, the method includes the steps of providing an optical system that has a pupil plane and an image plane at a detector; positioning the cornea in the pupil plane; passing a collimated beam of light through the cornea to produce at least two images in the image plane; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification. The apparatus includes: a source of collimated light: an optical system including a distorted grating and an imaging lens (which have a pupil plane, first and second virtual planes, and an image plane); structure for positioning the cornea in the pupil plane; and a computer. The structure for positioning the cornea (which is immersed in a suitable storage fluid) includes first and second plano/plano lenses. The first and second plano lens, which are substantially and perpendicular to and centered with respect to the axis, have less than λ/10 total distortions.
摘要翻译：用于确定角膜（无论是体外或体内）是否已被修改（手术或其他方式）的装置。该方法包括以下步骤：将准直光束（相干或非相干）通过角膜以产生畸变的波前; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。畸变波阵面的分析可以是高阶像差的存在，或表示修改的高斯特性。更具体地说，该方法包括以下步骤：提供在检测器处具有瞳孔平面和图像平面的光学系统; 将角膜定位在瞳孔平面中; 使准直的光束通过角膜，在图像平面中产生至少两个图像; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。该装置包括：准直光源：包括失真光栅和成像透镜（其具有瞳孔平面，第一和第二虚拟平面以及像平面）的光学系统; 用于将角膜定位在瞳孔平面中的结构; 和电脑。用于定位角膜（其浸入合适的储存液体中）的结构包括第一和第二平面/平视镜片。基本上和垂直于和相对于轴居中的第一和第二平面透镜具有小于λ/ 10的总失真。

4. 发明授权

US06464357B1 Wavefront characterization of corneas 失效
标题翻译：角膜的波前表征
公开(公告)号：US06464357B1
公开(公告)日：2002-10-15
申请号：US09895309
申请日：2001-06-29
申请人： Leonard John Otten, III , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
发明人： Leonard John Otten, III , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
IPC分类号： A61B310
CPC分类号： A61B3/1015 , A61B3/107 , A61F2/142 , G01J9/00
摘要： Apparatus for determining if a cornea (whether in vitro or in vivo) has been modified (either surgically or otherwise). The method includes the steps of: passing a beam of collimated light a (either coherent or incoherent) through the cornea to produce a distorted wavefront; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification. The analysis of the distorted wavefront can be for the presence of higher order aberrations, or Gausian characteristics which are indicative of modifications. More particularly, the method includes the steps of providing an optical system that has a pupil plane and an image plane at a detector; positioning the cornea in the pupil plane; passing a collimated beam of light through the cornea to produce at least two images in the image plane; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification. The apparatus includes: a source of collimated light: an optical system including a distorted grating and an imaging lens (which have a pupil plane, first and second virtual planes, and an image plane); structure for positioning the cornea in the pupil plane; and a computer. The structure for positioning the cornea (which is immersed in a suitable storage fluid) includes first and second plano/plano lenses. The first and second plano lens, which are substantially and perpendicular to and centered with respect to the axis, have less than &lgr;/10 total distortions.
摘要翻译：用于确定角膜（无论是体外或体内）是否已被修改（手术或其他方式）的装置。该方法包括以下步骤：将准直光束（相干或非相干）通过角膜以产生畸变的波前; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。畸变波阵面的分析可以是高阶像差的存在，或表示修改的高斯特性。更具体地说，该方法包括以下步骤：提供在检测器处具有瞳孔平面和图像平面的光学系统; 将角膜定位在瞳孔平面中; 使准直的光束通过角膜，在图像平面中产生至少两个图像; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。该装置包括：准直光源：包括失真光栅和成像透镜（其具有瞳孔平面，第一和第二虚拟平面以及像平面）的光学系统; 用于将角膜定位在瞳孔平面中的结构; 和电脑。用于定位角膜（其浸入合适的储存液体中）的结构包括第一和第二平面/平视镜片。第一和第二平面透镜基本上和垂直于并且相对于轴居中，具有小于lambd / 10的总失真。

5. 发明授权

US07712900B2 Wavefront characterization of corneas 失效
标题翻译：角膜的波前表征
公开(公告)号：US07712900B2
公开(公告)日：2010-05-11
申请号：US11825391
申请日：2007-07-03
申请人： Leonard John Otten , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
发明人： Leonard John Otten , Gavin R. G. Erry , Simon C. Woods , Paul Harrison
IPC分类号： A61B3/10
CPC分类号： A61B3/1015 , A61B3/107 , A61F2/142 , G01J9/00
摘要： Apparatus for determining whether cornea (vitro or in vivo) has been modified (surgically or otherwise). The method includes the steps of: passing a beam of collimated light through the cornea to produce a distorted wavefront; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification. The analysis of the distorted wavefront can be for the presence of higher order aberrations, or Gausian characteristics which are indicative of modifications. The method includes the steps of providing an optical system that has a pupil plane and an image plane at a detector; positioning the cornea in the pupil plane; passing a collimated beam of light through the cornea to produce at least two images in the image plane; determining the characteristics of the distorted wavefront; and analyzing the distorted wavefront for characteristics that identify the presence of a modification.
摘要翻译：用于确定角膜（体外或体内）是否已被修改（手术或其他）的装置。该方法包括以下步骤：将准直光束通过角膜以产生扭曲的波前; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。畸变波阵面的分析可以是高阶像差的存在，或表示修改的高斯特性。该方法包括以下步骤：在检测器处提供具有瞳孔平面和图像平面的光学系统; 将角膜定位在瞳孔平面中; 使准直的光束通过角膜，在图像平面中产生至少两个图像; 确定畸变波前的特征; 并分析畸变波阵面以识别修改的存在的特征。

6. 发明授权

US07638768B1 Laser wavefront characterization 有权
标题翻译：激光波前表征
公开(公告)号：US07638768B1
公开(公告)日：2009-12-29
申请号：US11820651
申请日：2007-06-19
申请人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
发明人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
IPC分类号： G01J5/00
CPC分类号： G01J9/00
摘要： The device and method of the present invention are useful for determining the characteristics of an infrared wavefront. The present invention involves positioning a beam of light containing the infrared wavefront to be characterized onto a distorted grating, using the grating to produce a plurality of images, determining the infrared wavefront from the plurality of images and analyzing the infrared wavefront for features that characterize the infrared wavefront.
摘要翻译：本发明的装置和方法可用于确定红外波前的特性。本发明涉及将包含要表征的红外波前的光束定位在失真的光栅上，使用光栅产生多个图像，从多个图像中确定红外波前，并分析红外波阵面的特征，红外波前。

7. 发明授权

US06331059B1 High resolution, multispectral, wide field of view retinal imager 有权
标题翻译：高分辨率，多光谱，宽视场视网膜成像仪
公开(公告)号：US06331059B1
公开(公告)日：2001-12-18
申请号：US09767256
申请日：2001-01-22
申请人： Alexis Kudryashov , Andrey Viktorovich Larichev , Leonard John Otten, III
发明人： Alexis Kudryashov , Andrey Viktorovich Larichev , Leonard John Otten, III
IPC分类号： A61B310
CPC分类号： A61B3/103
摘要： An ophthalmic instrument (for obtaining high resolution, wide field of area multi-spectral retinal images) including a fundus retinal imager, (which includes optics for illuminating and imaging the retina of the eye); apparatus for generating a reference beam coupled to the fundus optics to form a reference area on the retina; a wavefront sensor optically coupled to the fundus optics for measuring the wavefront produced by optical aberrations within the eye and the imager optics; wavefront compensation optics coupled to the fundus optics for correcting large, low order aberrations in the wavefront; a high resolution detector optically coupled to the imager optics and the wavefront compensation optics; and a computer (which is connected to the wavefront sensor, the wavefront compensation optics, and the high resolution camera) including an algorithm for correcting, small, high order aberrations on the wavefront and residual low order aberrations.
摘要翻译：包括眼底视网膜成像仪（其包括用于照射和成像眼睛的视网膜的光学器件）的眼科仪器（用于获得高分辨率，宽范围的多光谱视网膜图像）; 用于产生耦合到眼底光学器件以在视网膜上形成参考区域的参考光束的装置; 光学耦合到眼底光学器件的波前传感器，用于测量由眼睛和成像器光学器件内的光学像差产生的波前; 波前补偿光学耦合到眼底光学，用于校正波前的大，低阶像差; 光学耦合到成像器光学器件和波前补偿光学器件的高分辨率检测器; 以及计算机（其连接到波前传感器，波前补偿光学器件和高分辨率相机），其包括用于校正波前的残留低阶像差的小，高阶像差的算法。

8. 发明授权

US08882274B1 Laser wavefront characterization 有权
标题翻译：激光波前表征
公开(公告)号：US08882274B1
公开(公告)日：2014-11-11
申请号：US12536333
申请日：2009-08-05
申请人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
发明人： Leonard John Otten, III , Paul Harrison , Desirae L. Cuevas , Paul Fournier
IPC分类号： A61B3/10 , A61B3/00
CPC分类号： A61B3/1015 , A61B3/0008
摘要： The device and method of the present invention are useful for determining the characteristics of an infrared wavefront. The present invention involves positioning a beam of light containing the infrared wavefront to be characterized onto a distorted grating, using the grating to produce a plurality of images, determining the infrared wavefront from the plurality of images and analyzing the infrared wavefront for features that characterize the infrared wavefront.
摘要翻译：本发明的装置和方法可用于确定红外波前的特性。本发明涉及将包含要表征的红外波前的光束定位在失真的光栅上，使用光栅产生多个图像，从多个图像中确定红外波前，并分析红外波阵面的特征，红外波前。

9. 发明授权

US07419264B1 Ophthalmic aberrometer for measuring aberrations in the eye 有权
标题翻译：用于测量眼睛像差的眼科畸变仪
公开(公告)号：US07419264B1
公开(公告)日：2008-09-02
申请号：US10981996
申请日：2004-11-04
申请人： Leonard John Otten, III , Paul Harrison , Gavin Erry
发明人： Leonard John Otten, III , Paul Harrison , Gavin Erry
IPC分类号： A61B3/14
CPC分类号： A61B3/1015
摘要： A ophthalmic aberrometer uses a wavefront sensor aligned with an eye under examination through an optical path and a light source for introducing a light beam into the eye via the optical path, wherein the optical path has a reference through which the light beam passes before passing to an eye retina to form a reference spot on the retina, a focus dynamic range extender, and an astigmatism dynamic range extender positioned in the optical path between the reference and an eye under examination. The wavefront sensor is positioned to receive a wavefront reflected from the eye retina via the optical path.
摘要翻译：眼科畸变仪使用通过光路与被检查眼睛对准的波前传感器，以及用于经由光路将光束引入眼睛的光源，其中光路具有光束在经过之前通过的参考眼视网膜在视网膜上形成参考斑点，聚焦动态范围扩展器，以及位于参考眼和被检眼之间的光路中的像散动态范围扩展器。波前传感器被定位成经由光路接收从眼睛视网膜反射的波前。

10. 发明授权

US06992775B2 Hyperspectral retinal imager 有权
标题翻译：高光谱视网膜成像仪
公开(公告)号：US06992775B2
公开(公告)日：2006-01-31
申请号：US10651491
申请日：2003-08-29
申请人： Peter Soliz , Leonard John Otten, III , Paul Wiley Truitt
发明人： Peter Soliz , Leonard John Otten, III , Paul Wiley Truitt
IPC分类号： G01B9/02
CPC分类号： G01J3/453 , A61B3/12 , G01J3/28 , G01J3/2823
摘要： An ophthalmic instrument (for obtaining high resolution, wide field of area hyperspectral retinal images for various sized eyes) includes a fundus retinal imager, (which includes optics for illuminating and imaging the retina of the eye); apparatus for generating a real time image of the area being imaged and the location of the hyperspectral region of interest; a high efficiency spatially modulated common path Fourier transform hyperspectral imager, a high resolution detector optically coupled to the hyperspectral and fundus imager optics; and a computer (which is connected to the real time scene imager, the illumination source, and the high resolution camera) including an algorithm for recovery and calibration of the hyperspectral images.
摘要翻译：一种眼科仪器（用于获得高分辨率，宽范围的各种大小眼睛的高光谱视网膜图像）包括眼底视网膜成像仪（其包括用于照射和成像眼睛视网膜的光学器件）; 用于生成被成像区域的实时图像和感兴趣的高光谱区域的位置的装置; 高效率空间调制共路径傅里叶变换超光谱成像仪，高分辨率检测器，光学耦合到高光谱和眼底成像光学器件; 以及包括用于高光谱图像的恢复和校准的算法的计算机（连接到实时场景成像器，照明源和高分辨率相机）。

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