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1. 发明授权

US06606428B2 Angular-precision enhancement in free-space micromachined optical switches 有权
标题翻译：自由空间微加工光开关的角度精度增强
公开(公告)号：US06606428B2
公开(公告)日：2003-08-12
申请号：US09933726
申请日：2001-08-22
申请人： Evan Lee Goldstein , Lih-Yuan Lin , Robert William Tkach
发明人： Evan Lee Goldstein , Lih-Yuan Lin , Robert William Tkach
IPC分类号： G02B626
CPC分类号： G02B6/3584 , B81B3/0062 , G02B6/3518 , G02B26/0833
摘要： Integrated mechanical angular alignment-enhancement structures for incorporation into free-space micromachined optical switches are capable of achieving better than 0.1° micro-mirror angular precision and repeatability with the optical switches. The structures open the path to high port-count crossconnects with sufficiently low loss for deployment in practical optical-communications networks.
摘要翻译：用于结合到自由空间微加工光开关中的集成机械角度对准增强结构能够实现比光开关更好的0.1°微镜角度精度和重复性。该结构打开了高端口数交叉连接的路径，具有足够低的损耗，用于实际的光通信网络中的部署。

2. 发明授权

US06292600B1 Angular-precision enhancement in free-space micromachined optical switches 有权
标题翻译：自由空间微加工光开关的角度精度增强
公开(公告)号：US06292600B1
公开(公告)日：2001-09-18
申请号：US09472724
申请日：1999-12-27
申请人： Evan Lee Goldstein , Lih-Yuan Lin , Robert William Tkach
发明人： Evan Lee Goldstein , Lih-Yuan Lin , Robert William Tkach
IPC分类号： G02B626
CPC分类号： G02B6/3584 , B81B3/0062 , G02B6/3518 , G02B26/0833
摘要： Integrated mechanical angular alignment-enhancement structures for incorporation into free-space micromachined optical switches are capable of achieving better than 0.1° micro-mirror angular precision and repeatability with the optical switches. The structures open the path to high port-count crossconnects with sufficiently low loss for deployment in practical optical-communications networks.
摘要翻译：用于结合到自由空间微加工光开关中的集成机械角度对准增强结构能够实现比光开关更好的0.1°微镜角度精度和重复性。该结构打开了高端口数交叉连接的路径，具有足够低的损耗，用于实际的光通信网络中的部署。

3. 发明授权

US08778475B2 Patch for an underwire brassiere 有权
标题翻译：补丁为underwire胸罩
公开(公告)号：US08778475B2
公开(公告)日：2014-07-15
申请号：US13092309
申请日：2011-04-22
申请人： Lesa Michelle Joyce , Fredericka Lee Goldstein
发明人： Lesa Michelle Joyce , Fredericka Lee Goldstein
IPC分类号： A41C3/00 , B32B7/00
CPC分类号： A41H27/00 , A41C3/12 , Y10T428/15 , Y10T428/239 , Y10T428/2395 , Y10T428/249921 , Y10T428/2848
摘要： A patch covers a hole created on a fabric when a wire of an underwire bra breaks through, poking the delicate skin around the breast of a woman. The patch includes an outer layer made of a laminate material, an inner layer made of a close knit material. The outer layer may completely encase the inner layer.
摘要翻译：当电线胸罩的电线穿透时，贴片会覆盖在织物上产生的孔，从而刺穿女性乳房周围的微小皮肤。贴片包括由层压材料制成的外层，由紧密编织材料制成的内层。外层可以完全包住内层。

4. 发明授权

US06317532B1 Method and apparatus for low loss via geometrical optimization in free-space micro-machined optical switches 有权
标题翻译：自由空间微加工光开关几何优化的低损耗方法和装置
公开(公告)号：US06317532B1
公开(公告)日：2001-11-13
申请号：US09429786
申请日：1999-10-29
申请人： Lih Yuan Lin , Evan Lee Goldstein , Robert William Tkach
发明人： Lih Yuan Lin , Evan Lee Goldstein , Robert William Tkach
IPC分类号： G02B626
CPC分类号： G02B6/3518 , G02B6/3546 , G02B26/0841
摘要： A method and apparatus for minimizing optical loss associated with light beam divergence in a free-space micro-machined optical switch is presented. The coupling efficiency of a free-space micro-machined optical switch, that is, how efficiently the switch transfers an optical light beam from an emitting optical fiber to a receiving optical fiber, is obtained by calculating the overlap integral of the wave functions of an optical beam taken in a free-space mode at an entry point in the switch and in a fiber mode at a receiving fiber facet of the optical switch. Since the optical light beam diverges as it propagates through the optical switch, and the propagation distance increases with mirror size, that coupling efficiency is limited by the ratio of the optical light beam radius and the mirror radius of the switch. Thus, through careful measurements it becomes clear that an optimal value, for a given switch, of the ratio of the size of the beam in relation to the size of the mirror of the optical switch can be determined to optimize coupling efficiency and minimize data loss.
摘要翻译：提出了一种用于最小化与自由空间微加工光开关中的光束发散相关联的光损耗的方法和装置。通过计算自由空间微加工光开关的耦合效率，即开关将光束从发射光纤传递到接收光纤的效率是有效的，在光开关的接收光纤面处，在开关的入口点处以光纤模式以自由空间模式拍摄的光束。由于光学光束在通过光学开关传播时发散，并且传播距离随着镜面尺寸而增加，所以耦合效率受到光束半径与开关镜面半径的比率的限制。因此，通过仔细测量，可以清楚的是，可以确定给定开关的光束尺寸与光开关的反射镜尺寸之比的最佳值，以优化耦合效率并最小化数据丢失。

5. 发明申请

US20110262677A1 PATCH FOR AN UNDERWIRE BRASSIERE 有权
标题翻译：适用于内部布鲁塞尔
公开(公告)号：US20110262677A1
公开(公告)日：2011-10-27
申请号：US13092309
申请日：2011-04-22
申请人： LESA MICHELLE JOYCE , Fredericka Lee Goldstein
发明人： LESA MICHELLE JOYCE , Fredericka Lee Goldstein
IPC分类号： B32B7/00 , A41C3/00
CPC分类号： A41H27/00 , A41C3/12 , Y10T428/15 , Y10T428/239 , Y10T428/2395 , Y10T428/249921 , Y10T428/2848
摘要： A patch covers a hole created on a fabric when a wire of an underwire bra breaks through, poking the delicate skin around the breast of a woman. The patch includes an outer layer made of a laminate material, an inner layer made of a high strength material.. The outer layer may completely encase the inner layer.
摘要翻译：当电线胸罩的电线穿透时，贴片会覆盖在织物上产生的孔，从而刺穿女性乳房周围的微小皮肤。贴片包括由层压材料制成的外层，由高强度材料制成的内层。外层可以完全包住内层。

6. 发明申请

US20080088795A1 Ocular imaging 有权
标题翻译：眼部成像
公开(公告)号：US20080088795A1
公开(公告)日：2008-04-17
申请号：US11786514
申请日：2007-04-11
申请人： Lee Goldstein , Norman Ford , Leo Chylack , Paul Hartung , Marc Friedman , Evan Sherr , Stephen Fantone
发明人： Lee Goldstein , Norman Ford , Leo Chylack , Paul Hartung , Marc Friedman , Evan Sherr , Stephen Fantone
IPC分类号： A61B3/14
CPC分类号： A61B3/14 , A61B3/117
摘要： A system for performing quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye includes a light source configured to transmit light toward the subject's eye, a lens configured to focus light sent from the source and scattered by the subject's eye, a measurement reflector disposed to receive at least a portion of the focused light and configured to reflect a first portion of the received light, a camera configured and disposed to receive the first portion of the received light and configured to provide indicia of an image corresponding to the first portion of the received light, and a processor coupled to the camera and configured to analyze intensities of light in the image to determine a location of a reference point corresponding to an interface of a portion of the eye.
摘要翻译：用于在受试者的眼睛上执行准弹性光散射和荧光配体扫描的系统包括：被配置为朝向被检者的眼睛透射光的光源;被配置为聚焦从源发射并被受检者眼睛散射的光的透镜;测量反射器被配置为接收聚焦光的至少一部分并且被配置为反射接收到的光的第一部分;配置和设置成接收所接收的光的第一部分并被配置为提供对应于第一部分的图像的标记的照相机以及耦合到相机并被配置为分析图像中的光的强度以确定与眼睛的一部分的界面相对应的参考点的位置的处理器。

7. 发明申请

US20050095653A1 Ocular diagnosis of alzheimer's disease 审中-公开
标题翻译：眼科诊断阿尔茨海默病
公开(公告)号：US20050095653A1
公开(公告)日：2005-05-05
申请号：US11012937
申请日：2004-12-15
申请人： Lee Goldstein , Leo Chylack
发明人： Lee Goldstein , Leo Chylack
IPC分类号： G01N33/50 , A61K49/00 , G01N33/15 , G01N33/53 , G01N33/566 , C07K14/47 , C12Q1/68
CPC分类号： A61K49/0021
摘要： The invention features a method of diagnosing or providing a prognosis regarding the state of Alzheimer's Disease in a mammal by contacting an ocular tissue with a detectably-labeled compound, which binds to an amyloid protein. An increase in binding of the compound to the ocular tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease.
摘要翻译：本发明的特征在于一种通过使眼组织与可结合标记的化合物接触的方法来诊断或提供关于阿尔茨海默病状态的预后，其结合淀粉样蛋白。与正常对照水平的结合相比，化合物与眼组织的结合增加表明哺乳动物患有或有发展为阿尔茨海默氏病的风险。

8. 发明授权

US06243507B1 Connection-verification in optical MEMS crossconnects via mirror-dither 有权
标题翻译：通过镜像抖动在光学MEMS交叉连接中进行连接验证
公开(公告)号：US06243507B1
公开(公告)日：2001-06-05
申请号：US09472682
申请日：1999-12-27
申请人： Evan Lee Goldstein , Lih-Yuan Lin , Leda Maria Lunardi
发明人： Evan Lee Goldstein , Lih-Yuan Lin , Leda Maria Lunardi
IPC分类号： G02B612
CPC分类号： G02B6/3588 , G02B6/3512 , G02B6/3518 , G02B6/3546 , G02B6/357 , G02B6/358 , G02B6/4204 , G02B26/0833
摘要： Integrated connection-verification system for use in a micro-electro-mechanical system (MEMS) crossconnect device. The system uses application of a dithering signal such as a sinusoidal bias to an electrode plate associated with a micro-mirror switching element to dither the micro-mirror. The optical signal from the dithering micro-mirror is fed through a beam splitter, a portion of the optical signal thus being directed to a photodetector. If intensity modulation in the optical signal corresponding to the frequency of the dithering signal is detected by the photodetector associated with the micro-mirror, the connection path between the desired input and output ports is verified.
摘要翻译：用于微机电系统（MEMS）交叉连接装置的集成连接验证系统。该系统使用诸如正弦偏压的抖动信号施加到与微镜开关元件相关联的电极板来抖动微反射镜。来自抖动微镜的光信号通过分束器馈送，因此光信号的一部分被引导到光电检测器。如果由与微镜相关联的光电检测器检测到与抖动信号的频率相对应的光信号中的强度调制，则验证所需输入和输出端口之间的连接路径。

9. 发明申请

US20050084918A1 Method for the identification of agents that inhibit or promote cataracts and uses thereof 失效
标题翻译：用于鉴定抑制或促进白内障及其用途的药剂的方法
公开(公告)号：US20050084918A1
公开(公告)日：2005-04-21
申请号：US10983780
申请日：2004-11-09
申请人： Ashley Bush , Lee Goldstein
发明人： Ashley Bush , Lee Goldstein
IPC分类号： G01N33/50 , A61K31/47 , A61K45/00 , A61P27/12 , C07D215/28 , G01N33/15 , G01N33/483 , G01N33/53 , G01N33/68 , C12Q1/26 , G01N33/537 , G01N33/543
CPC分类号： G01N33/6893 , A61K31/47 , G01N2500/04 , G01N2800/166
摘要： Described are methods for the identification of agents useful in the treatment or prevention of cataracts. Also described are methods for the identification of agents that may inadvertently promote or accelerate the formation of cataracts, and methods of treating or preventing injuries to or diseases of the ocular lens, retina and/or macular. More specifically, the invention describes methods for the identification of pharmacological agents useful in treating cataracts by inhibiting the cross-linking of eye lens proteins.
摘要翻译：描述了用于鉴定可用于治疗或预防白内障的药剂的方法。还描述了用于鉴定可能不经意地促进或加速白内障形成的药剂的方法，以及治疗或预防眼透镜，视网膜和/或黄斑的损伤或疾病的方法。更具体地，本发明描述了通过抑制眼晶状体蛋白质的交联来鉴定可用于治疗白内障的药理学试剂的方法。

10. 发明授权

US06337859B1 Non-blocking crossconnect apparatus 失效
标题翻译：非阻塞交叉连接装置
公开(公告)号：US06337859B1
公开(公告)日：2002-01-08
申请号：US09002241
申请日：1997-12-31
申请人： Evan Lee Goldstein , Lih-Yuan Lin , Adel Abdel Moneim Saleh , Jane Marie Simmons
发明人： Evan Lee Goldstein , Lih-Yuan Lin , Adel Abdel Moneim Saleh , Jane Marie Simmons
IPC分类号： H04Q116
CPC分类号： H04Q3/68 , H04Q2213/13076 , H04Q2213/13146 , H04Q2213/13166 , H04Q2213/1334 , H04Q2213/13341
摘要： A non-blocking crossconnect apparatus includes a primary bi-directional crossconnect device and a plurality of secondary bi-directional crossconnect devices. The primary crossconnect device has a plurality of pairs of bi-directional signal ports. A first one of each of the plurality of pairs of the bi-directional signal ports are arranged in a first set and a corresponding second one of each of the plurality of pairs of the bi-directional signal ports are arranged in a second set. Each secondary crossconnect device is associated with a respective one of the plurality of pairs of bi-directional signal ports and has a pair of secondary bi-directional signal ports and a pair of bi-directional signal leads. A first one of each pair of the bi-directional signal leads is operably connected to a respective one of the bi-directional signal ports in the first set and a second one of each pair of the bi-directional signal leads is operably connected to a respective one of the bi-directional signal ports in the second set. By utilizing symmetry and the bi-directional nature of communication lines, the present invention yields a rearrangeably non-blocking crossconnect apparatus as well as a strictly non-blocking crossconnect apparatus.
摘要翻译：非阻塞交叉连接装置包括主要双向交叉连接装置和多个次级双向交叉连接装置。主交叉连接装置具有多对双向信号端口。多对双向信号端口中的每一对中的第一个布置在第一组中，并且多对双向信号端口中的每一对双向信号端口中的相应的第二组布置在第二组中。每个次级交叉连接装置与多对双向信号端口中的相应一个相关联并且具有一对辅助双向信号端口和一对双向信号引线。每对双向信号引线中的第一个可操作地连接到第一组中的双向信号端口中的相应一个，并且每对双向信号引线中的第二个可操作地连接到相应的第二组中的双向信号端口之一。通过利用通信线路的对称性和双向性，本发明产生了可重新布置的非阻塞交叉连接装置以及严格无阻塞的交叉连接装置。

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