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1. 发明申请

US20100144965A1 EPOXY THERMOSET COMPOSITIONS COMPRISING EXCESS EPOXY RESIN AND PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：包含环氧树脂的环氧热固化剂组合物及其制备方法
公开(公告)号：US20100144965A1
公开(公告)日：2010-06-10
申请号：US12598520
申请日：2008-04-22
申请人： Maurice Joel Marks , Courtney Lawrence Sherman
发明人： Maurice Joel Marks , Courtney Lawrence Sherman
IPC分类号： C08L63/00 , C08G65/02 , C08G59/68
CPC分类号： C08G59/18
摘要： In one aspect, embodiments disclosed herein relate to a process for curing a thermoset composition, including: reacting a curable composition comprising an epoxy resin, an epoxy-reactive compound, and a catalyst, wherein there is a stoichiometric excess of the epoxy resin; to form an intermediate product having unreacted epoxy groups and secondary hydroxyl groups; and etherifying at least a portion of the unreacted epoxy groups and the secondary hydroxyl groups, catalyzed by the catalyst, to form a thermoset composition.
摘要翻译：一方面，本文公开的实施方案涉及用于固化热固性组合物的方法，包括：使包含环氧树脂，环氧反应性化合物和催化剂的可固化组合物反应，其中存在化学计量过量的环氧树脂; 形成具有未反应的环氧基和仲羟基的中间产物; 以及醚化由催化剂催化的至少一部分未反应的环氧基和仲羟基以形成热固性组合物。

2. 发明申请

US20050245974A1 Methods and devices to guide therapy for ventricular fibrillation based on waveform analysis and survival benefit analysis 失效
标题翻译：基于波形分析和生存效益分析指导心室颤动治疗的方法和装置
公开(公告)号：US20050245974A1
公开(公告)日：2005-11-03
申请号：US11020315
申请日：2004-12-27
申请人： Lawrence Sherman
发明人： Lawrence Sherman
IPC分类号： A61B5/046 , A61N1/39
CPC分类号： A61N1/39 , A61B5/046 , A61B5/7257 , A61N1/3925
摘要： A method of determining a state of ventricular fibrillation from a waveform, includes: performing calculations on the Fourier transform of the waveform voltage values by using the quotient of the power in a high frequency band and of the power in a low frequency band; and determining the state of ventricular fibrillation by relating this ratio to the state of ventricular fibrillation. A defibrillation system for use in treatment of ventricular fibrillation includes at least one sensor to measure heart rhythm and at least one applicator to apply a defibrillation shock to a patient. The system further includes at least one processor which is adapted to calculate the ratio and also to obtain user input regarding survival of subgroups and average response times in the user's domain which allows calculation of an estimated maximum overall survival and selection of an optimum threshold for the ratio measure based on this maximum. The system further includes a user interface system in operative connection with the processor to provide information related to the ratio to a user.
摘要翻译：一种从波形确定心室颤动的状态的方法包括：通过使用高频带中的功率商和低频带功率的波形电压值的傅里叶变换来执行计算; 并通过将该比率与心室颤动的状态相关联来确定心室颤动的状态。用于治疗心室纤维性颤动的除颤系统包括至少一个测量心律的传感器和至少一个施加器以对患者施加除颤电击。该系统还包括至少一个处理器，其适于计算该比率，并且还可以获得与用户领域中的子组的生存和平均响应时间相关的用户输入，其允许计算估计的最大总生存期并选择最佳阈值基于此最大值的比率度量。该系统还包括与处理器可操作地连接的用户界面系统，以向用户提供与该比率有关的信息。

3. 发明授权

US4841078A Benzopyrans 失效
标题翻译：苯并吡喃
公开(公告)号：US4841078A
公开(公告)日：1989-06-20
申请号：US639038
申请日：1984-08-09
申请人： James F. Eggler , Michael R. Johnson , Lawrence Sherman
发明人： James F. Eggler , Michael R. Johnson , Lawrence Sherman
IPC分类号： C07C37/055 , C07C39/08 , C07C43/23 , C07C61/39 , C07D311/22 , C07D311/58 , C07D405/12 , C07D407/12 , C07D417/12 , C07D491/10 , C07D493/06 , C07D493/10
CPC分类号： C07D405/12 , C07C255/00 , C07C37/055 , C07C41/30 , C07C61/39 , C07D311/22 , C07D311/58 , C07D407/12 , C07D417/12 , C07D491/10 , C07D493/06 , C07D493/10
摘要： Bicyclic fused benzenoid compounds of the formula ##STR1## and pharmaceutically acceptable cationic and acid addition salts thereof, where M is O, CH.sub.2 or NR.sub.6 ; R.sub.6 is hydrogen, formyl, carbobenzyloxy or certain carboalkoxyalkyl, alkanoyl, alkyl, aralkyl or aralkylcarbonyl groups;A' is:(1) A where one of A and B is hydrogen such that when A is hydrogen, B is C(R.sub.2 R.sub.3)(CH.sub.2).sub.f Q and f is 1 or 2; when B is hydrogen, A is C(R.sub.2 R.sub.3)(CH.sub.2).sub.f Q and f is 0 or 1, when taken together A and OR.sub.1 form a lactone or certain derivatives thereof;(2) A' is ##STR2## (3) A' is Q.sub.3 ; Q is CO.sub.2 R.sub.7, COR.sub.8, C(OH)R.sub.8 R.sub.9, CN, CONR.sub.12 R.sub.13, CH.sub.2 NR.sub.12 R.sub.13, CH.sub.2 NHCOR.sub.14, CH.sub.2 NHSO.sub.2 R.sub.17 or 5-tetrazoyl;Q.sub.3 is ##STR3## 5-tetrazolyl, CH.sub.2 CONHCOR.sub.7, COOH or certain ester, amide, carboximido or sulfonimido derivatives thereof, CONHOH, CONHCONH.sub.2, or COCH.sub.2 Q.sub.4 where Q.sub.4 is CN or COOH or certain esters thereof;R.sub.1 is hydrogen, benzyl or certain acyl groups; R.sub.4 is hydrogen, certain alkyl or certain aralkyl groups; R.sub.5 is hydrogen or certain alkyl groups; Z is (C.sub.1 -C.sub.9)alkylene, optionally interrupted by O, S, SO or SO.sub.2 ; and W is hydrogen, methyl, certain aryl or cycloalkyl groups; useful in mammals as analgesics, tranquilizers, anteimetic agents, diuretics, anticonvulsants, antidiarrheals, antitussives, in treatment of glaucoma, and intermediates therefore.
摘要翻译：式（I'）的双环稠合苯并噻唑类化合物及其药学上可接受的阳离子和酸加成盐，其中M为O，CH 2或NR 6; R6是氢，甲酰基，苄氧羰基或某些烷氧基烷基，烷酰基，烷基，芳烷基或芳烷基羰基; A'为：（1）其中A和B之一为氢，使得当A为氢时，B为C（R2R3）（CH2）fQ且f为1或2; 当B为氢时，A为C（R2R3）（CH2）fQ，f为0或1，当A和OR1一起形成内酯或其某些衍生物时; （2）A'是（3）A'是Q3; Q是CO 2 R 7，COR 8，C（OH）R 8 R 9，CN，CONR 12 R 13，CH 2 NR 12 R 13，CH 2 NHCOR 14，CH 2 NHSO 2 R 17或5-四唑基; Q 4是CN或COOH或其某些酯; Q 3是CN，COOH或其某些酯;其中Q 4是CN或COOH或其某些酯; R1是氢，苄基或某些酰基; R4是氢，某些烷基或某些芳烷基; R5是氢或某些烷基; Z是（C1-C9）亚烷基，任选地被O，S，SO或SO 2中断; W是氢，甲基，某些芳基或环烷基; 因此在哺乳动物中作为止痛剂，止痛剂，促炎剂，利尿剂，抗惊厥药，止泻药，镇咳药，治疗青光眼有用。

4. 发明申请

US20140057242A1 Personalized Electronic Education 审中-公开
标题翻译：个性化电子教育
公开(公告)号：US20140057242A1
公开(公告)日：2014-02-27
申请号：US13595664
申请日：2012-08-27
申请人： Lawrence SHERMAN
发明人： Lawrence SHERMAN
IPC分类号： G09B7/00
CPC分类号： G09B7/00
摘要： In general, in an aspect, embodiments of the invention can provide, a semi- or fully-automatic computer-implemented method for personalized electronic education of a student, the method including, performing a computerized assessment of the student, using a knowledge assessment module, to determine a knowledge deficit of the student associated with at least one concept, defining a learning profile for the student using a learning profile generation module, receiving, at a server module, a computerized explanation submission based on the learning profile, evaluating, using an explanation submission evaluation module of the server module, the received explanation submission based on an understanding of the concept by the student after presentation to the student of the explanation submission, and rating, using the explanation submission evaluation module, the explanation submission based on the evaluation.
摘要翻译：一般来说，在一方面，本发明的实施例可以提供一种半自动或全自动的计算机实现的用于学生个性化电子教育的方法，所述方法包括：使用知识评估模块对学生进行计算机化评估确定与至少一个概念相关联的学生的知识缺陷，使用学习简档生成模块定义学生的学习简档，在服务器模块处接收基于学习简档的计算机化解释提交，评估，使用服务器模块的说明提交评估模块，基于在向学生呈现说明提交之后对学生的概念的理解的接收到的解释提交，以及使用解释提交评估模块进行评价，基于评估。

5. 发明授权

US3398221A Method of producing shoe inserts 失效
标题翻译：生产鞋垫的方法
公开(公告)号：US3398221A
公开(公告)日：1968-08-20
申请号：US46264965
申请日：1965-06-09
申请人： LAWRENCE SHERMAN , GARRY SHERMAN
发明人： LAWRENCE SHERMAN , GARRY SHERMAN
IPC分类号： A43B7/28
CPC分类号： A43B7/28 , Y10T156/1028

6. 发明授权

US4118559A 9-Hydroxyhexahydrodibenzo[O,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans and intermediates therefor 失效
标题翻译： 9-羟基六氢二苯并[8 O，d {9吡喃，1-取代-9-羟基六氢二苯并[b，d] {9]吡喃及其中间体
公开(公告)号：US4118559A
公开(公告)日：1978-10-03
申请号：US804306
申请日：1977-06-07
申请人： Michael Ross Johnson , Lawrence Sherman Melvin, Jr.
发明人： Michael Ross Johnson , Lawrence Sherman Melvin, Jr.
IPC分类号： A61K31/35 , A61K31/352 , A61P25/04 , C07C37/055 , C07C43/205 , C07C45/45 , C07D307/88 , C07D311/22 , C07D311/80 , C07D493/10 , C07D405/06
CPC分类号： C07D493/10 , C07C37/055 , C07C43/205 , C07C43/2055 , C07C45/45 , C07D307/88 , C07D311/22 , C07D311/80
摘要： 9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans wherein the substituent is hydrogen, methyl, hydroxymethyl, formyl, carboxy, carbamyl, amino, mono- and di-alkylamino, alkanoylamino, phenalkylsulfonamido or alkylsulfonamido, and the corresponding 9-ketones, all of which are useful as CNS agents, especially as analgesics and tranquilizers, intermediates therefor the processes for their preparation.
摘要翻译： 9-羟基六氢二苯并[b，d]吡喃，1-取代-9-羟基六氢二苯并[b，d]吡喃，其中取代基是氢，甲基，羟甲基，甲酰基，羧基，氨基甲酰基，氨基，一烷基氨基和二烷基氨基，烷酰基氨基，苯烷基亚磺酰氨基或烷基磺酰氨基，以及相应的9-酮，它们都可用作CNS剂，特别是作为止痛剂和镇定剂，其制备方法的中间体。

7. 发明申请

US20050245973A1 Methods and devices to characterize the probability of successful defibrillation and determine treatments for ventricular fibrillation 失效
标题翻译：表征成功除颤的概率的方法和装置，并确定心室颤动的治疗
公开(公告)号：US20050245973A1
公开(公告)日：2005-11-03
申请号：US10955898
申请日：2004-09-30
申请人： Lawrence Sherman
发明人： Lawrence Sherman
IPC分类号： A61B5/046 , A61N1/39
CPC分类号： A61N1/3925 , A61B5/046
摘要： A method of determining a state of ventricular fibrillation from waveform obtained at sampling rates and with filtering typical of current clinical devices, includes: performing calculations to produce the autocorrelation function of the measured ventricular fibrillation heart rhythm over a given range of lags; determining a first value related to the sum of the absolute values of the series of values forming the autocorrelation function over the given range of lags over the period of time; and determining the state of ventricular fibrillation by relating the first value or the logarithm of the first value to the state of ventricular fibrillation. A defibrillation system for use in treatment of ventricular fibrillation includes at least one sensor to measure heart rhythm and at least one applicator to apply a defibrillation shock to a patient. The system further includes at least one processor in communication with the sensor and the applicator which is adapted to calculate the first value related to the sum of the absolute values of the values in the autocorrelation function over the given range of lags over the period of time. The system further includes a user interface system in operative connection with the processor to provide information related to the first value to a user.
摘要翻译：根据以采样率获得的波形和当前临床装置典型的滤波来确定心室颤动状态的方法包括：执行计算以在给定的滞后范围内产生所测量的心室颤动心律的自相关函数; 确定在所述时间段内在所述滞后范围内形成所述自相关函数的所述一系列值的绝对值的和相关的第一值; 以及通过将第一值的第一值或对数与心室颤动的状态相关联来确定心室颤动的状态。用于治疗心室纤维性颤动的除颤系统包括至少一个测量心律的传感器和至少一个施加器以对患者施加除颤电击。所述系统还包括与所述传感器和所述施加器通信的至少一个处理器，所述至少一个处理器适于计算与所述自动相关函数中的所述值的所述绝对值之和相对于所述延迟的给定范围在所述时间段内的所述第一值。该系统还包括与处理器可操作地连接的用户接口系统，以向用户提供与第一值有关的信息。

8. 发明申请

US20050222951A1 Systems and methods of targeting savings 审中-公开
标题翻译：瞄准储蓄的制度和方法
公开(公告)号：US20050222951A1
公开(公告)日：2005-10-06
申请号：US10817139
申请日：2004-04-02
申请人： Lawrence Sherman
发明人： Lawrence Sherman
IPC分类号： G06Q40/00 , G06F17/60
CPC分类号： G06Q40/02 , G06Q20/102
摘要： Systems and methods of targeting savings deposits are provided that enable a depositor, such as a customer of a financial institution, to save money for various purposes or goals. A financial institution can make offers for targeting savings deposits to its customers using a financial statement that the financial institution prepares and provides to its customers to report information related to customers' financial accounts. Such offers can be solicited or unsolicited and can include one or more targeted savings plans customized to meet customers' savings goals. The financial statement can be further used to enable customers to enroll in one or more targeted savings plans and to make savings transactions according to such plans. A credit card account statement can be used for such purposes such that customers can make targeted savings deposits along with making payments to credit card accounts.
摘要翻译：提供了针对储蓄存款的系统和方法，使存款人（如金融机构的客户）可以为各种目的或目标节省资金。金融机构可以使用财务报表向客户提供定向储蓄存款的报价，金融机构准备并提供给客户报告与客户财务账目相关的信息。这些优惠可以被请求或主动提供，并且可以包括一个或多个定制的储蓄计划，以满足客户的储蓄目标。财务报表可以进一步用于使客户能够注册一个或多个有针对性的储蓄计划，并根据此类计划进行储蓄交易。信用卡帐户对帐单可用于此类目的，以便客户可以进行有针对性的储蓄存款以及向信用卡账户付款。

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