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1. 发明申请

US20100069994A1 METHODS OF INDUCING PARESTHESIA USING WIRELESS NEUROSTIMULATION 审中-公开
标题翻译：使用无线神经元诱导麻醉的方法
公开(公告)号：US20100069994A1
公开(公告)日：2010-03-18
申请号：US12624383
申请日：2009-11-23
申请人： Lawrence James Cauller
发明人： Lawrence James Cauller
IPC分类号： A61N1/34
CPC分类号： A61N1/0551 , A61N1/0529 , A61N1/0536 , A61N1/0556 , A61N1/08
摘要： A grooved electrode adapted for interfacing cellular matter is provided. The grooved electrode includes grooves adapted for electrically interfacing the grooved electrode with cellular matter growing along the body of the grooved electrode. Further, the grooved electrode includes a wireless transponder adapted to electrically interface with cellular matter and to relay such interactions via RF signals. The RF signals received by the wireless transponder are modulated in response to electrical signals generated by the cellular matter, which are detected by the transponder. The grooved electrode may be implanted within peripheral nerves for treating various neurological conditions, which may include nerve rehabilitation and prosthetic actuation, severe pain, obstructive sleep apnea and so forth.
摘要翻译：提供了一种适用于接口细胞物质的开槽电极。带槽电极包括适于将带槽电极与沿着带槽电极主体生长的细胞物质电接口的凹槽。此外，带槽电极包括适于与蜂窝物质电接口并经由RF信号中继这种相互作用的无线应答器。由无线应答器接收的RF信号响应于由应答器检测到的由蜂窝状物质产生的电信号进行调制。沟槽电极可以植入外周神经中，用于治疗各种神经疾病，其可以包括神经康复和假体致动，严重的疼痛，阻塞性睡眠呼吸暂停等。

2. 发明申请

US20080319506A1 Grooved electrode and wireless microtransponder system 有权
标题翻译：沟槽电极和无线微型应答器系统
公开(公告)号：US20080319506A1
公开(公告)日：2008-12-25
申请号：US11821678
申请日：2007-06-25
申请人： Lawrence James Cauller
发明人： Lawrence James Cauller
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0529 , A61N1/0536 , A61N1/0556 , A61N1/08
摘要： A grooved electrode adapted for interfacing cellular matter is provided. The grooved electrode includes grooves adapted for electrically interfacing the grooved electrode with cellular matter growing along the body of the grooved electrode. Further, the grooved electrode includes a wireless transponder adapted to electrically interface with cellular matter and to relay such interactions via RF signals. The RF signals received by the wireless transponder are modulated in response to electrical signals generated by the cellular matter, which are detected by the transponder. The grooved electrode may be implanted within peripheral nerves for treating various neurological conditions, which may include nerve rehabilitation and prosthetic actuation, severe pain, obstructive sleep apnea and so forth.
摘要翻译：提供了一种适用于接口细胞物质的开槽电极。带槽电极包括适于将带槽电极与沿着带槽电极主体生长的细胞物质电接口的凹槽。此外，带槽电极包括适于与蜂窝物质电接口并经由RF信号中继这种相互作用的无线应答器。由无线应答器接收的RF信号响应于由应答器检测到的由蜂窝状物质产生的电信号进行调制。沟槽电极可以植入外周神经中，用于治疗各种神经疾病，其可以包括神经康复和假体致动，严重的疼痛，阻塞性睡眠呼吸暂停等。

3. 发明申请

US20120065701A1 Grooved Electrode and Wireless Microtransponder System 审中-公开
标题翻译：沟槽电极和无线微型应答器系统
公开(公告)号：US20120065701A1
公开(公告)日：2012-03-15
申请号：US13298185
申请日：2011-11-16
申请人： Lawrence James Cauller
发明人： Lawrence James Cauller
IPC分类号： A61N1/375 , B82Y5/00
CPC分类号： A61N1/0551 , A61N1/0529 , A61N1/0536 , A61N1/0556 , A61N1/08
摘要： A grooved electrode adapted for interfacing cellular matter is provided. The grooved electrode includes grooves adapted for electrically interfacing the grooved electrode with cellular matter growing along the body of the grooved electrode. Further, the grooved electrode includes a wireless transponder adapted to electrically interface with cellular matter and to relay such interactions via RF signals. The RF signals received by the wireless transponder are modulated in response to electrical signals generated by the cellular matter, which are detected by the transponder. The grooved electrode may be implanted within peripheral nerves for treating various neurological conditions, which may include nerve rehabilitation and prosthetic actuation, severe pain, obstructive sleep apnea and so forth.
摘要翻译：提供了一种适用于接口细胞物质的开槽电极。带槽电极包括适于将带槽电极与沿着带槽电极主体生长的细胞物质电接口的凹槽。此外，带槽电极包括适于与蜂窝物质电接口并经由RF信号中继这种相互作用的无线应答器。由无线应答器接收的RF信号响应于由应答器检测到的由蜂窝状物质产生的电信号进行调制。沟槽电极可以植入外周神经中，用于治疗各种神经疾病，其可以包括神经康复和假体致动，严重的疼痛，阻塞性睡眠呼吸暂停等。

4. 发明申请

US20100022908A1 System and Method for Interfacing Cellular Matter with a Machine 审中-公开
标题翻译：将细胞与机器接触的系统和方法
公开(公告)号：US20100022908A1
公开(公告)日：2010-01-28
申请号：US12558734
申请日：2009-09-14
申请人： Lawrence James Cauller
发明人： Lawrence James Cauller
IPC分类号： A61B5/0476 , A61B5/0484
CPC分类号： A61B5/415 , A61B5/0031 , A61B5/0476 , A61B5/418 , A61B2560/0219 , G06F3/011
摘要： A system for interfacing cellular matter with a machine comprising a transponder implantable in cellular matter and configured to detect a first signal. The system also includes a receiver external to the cellular matter and configured to receive a second signal in response to the transponder detection of the first signal. A transmitter is also included in the system to transmit a third signal to a machine in response to the receiver receipt of the second signal.
摘要翻译：一种用于将细胞物质与机器接口的系统，包括可移植到细胞物质中并被配置为检测第一信号的应答器。该系统还包括在蜂窝状物外部的接收器，并且被配置为响应于第一信号的应答器检测而接收第二信号。系统中还包括发射机，以响应于接收机接收第二信号而将第三信号发送到机器。

5. 发明申请

US20090163889A1 Biodelivery System for Microtransponder Array 审中-公开
标题翻译：微型应答器阵列生物传送系统
公开(公告)号：US20090163889A1
公开(公告)日：2009-06-25
申请号：US12323952
申请日：2008-11-26
申请人： Lawrence James Cauller , Richard Weiner
发明人： Lawrence James Cauller , Richard Weiner
IPC分类号： A61M5/32 , A61M5/315
CPC分类号： A61N1/37229 , A61B5/6849 , A61B2560/0219 , A61B2562/028 , A61N1/36071 , A61N1/36125 , A61N1/37205 , A61N1/3756
摘要： Methods and devices for hypodermic implanting micro-transponders into a body. The method includes preassembling an array of micro-transponders into a cannula which is configured for tissue penetration and injection.
摘要翻译：用于皮下注射微转发体进入体内的方法和装置。该方法包括将微转发器阵列预先组装到配置成用于组织穿透和注射的插管中。

6. 发明授权

US09089707B2 Systems, methods and devices for paired plasticity 有权
标题翻译：用于成对可塑性的系统，方法和装置
公开(公告)号：US09089707B2
公开(公告)日：2015-07-28
申请号：US12485040
申请日：2009-06-15
申请人： Michael P Kilgard , Lawrence James Cauller , Navzer Engineer , Christa McIntyre , Will Rosellini
发明人： Michael P Kilgard , Lawrence James Cauller , Navzer Engineer , Christa McIntyre , Will Rosellini
IPC分类号： A61N1/00 , A61N1/36 , G09B23/28 , A61M21/02 , H04R25/00 , A61F11/00 , A61M21/00
CPC分类号： A61N1/36167 , A61F11/00 , A61M21/00 , A61M21/02 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2021/0077 , A61M2205/3515 , A61M2230/06 , A61M2230/08 , A61M2230/10 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/50 , A61M2230/60 , A61M2230/65 , A61N1/36014 , A61N1/36053 , A61N1/36067 , A61N1/36082 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36139 , A61N5/0618 , A61N5/0622 , G09B19/00 , G09B19/003 , G09B23/28 , H04R25/75
摘要： Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
摘要翻译：用于配对训练的系统，方法和装置包括时间控制，以便可以同时提供训练和神经刺激。配对培训可能包括治疗，康复和绩效增强培训。影响神经的神经刺激，如影响皮层下的区域，如基底核，坐骨神经或杏仁核诱导脑中的可塑性，增强各种疗法的作用，例如用于治疗耳鸣，中风，创伤性脑损伤和创伤后应激障碍。

7. 发明授权

US07630771B2 Grooved electrode and wireless microtransponder system 有权
标题翻译：沟槽电极和无线微型应答器系统
公开(公告)号：US07630771B2
公开(公告)日：2009-12-08
申请号：US11821678
申请日：2007-06-25
申请人： Lawrence James Cauller
发明人： Lawrence James Cauller
IPC分类号： A61N1/375
CPC分类号： A61N1/0551 , A61N1/0529 , A61N1/0536 , A61N1/0556 , A61N1/08
摘要： A grooved electrode adapted for interfacing cellular matter is provided. The grooved electrode includes grooves adapted for electrically interfacing the grooved electrode with cellular matter growing along the body of the grooved electrode. Further, the grooved electrode includes a wireless transponder adapted to electrically interface with cellular matter and to relay such interactions via RF signals. The RF signals received by the wireless transponder are modulated in response to electrical signals generated by the cellular matter, which are detected by the transponder. The grooved electrode may be implanted within peripheral nerves for treating various neurological conditions, which may include nerve rehabilitation and prosthetic actuation, severe pain, obstructive sleep apnea and so forth.
摘要翻译：提供了一种适用于接口细胞物质的开槽电极。带槽电极包括适于将带槽电极与沿着带槽电极主体生长的细胞物质电接口的凹槽。此外，带槽电极包括适于与蜂窝物质电接口并经由RF信号中继这种相互作用的无线应答器。由无线应答器接收的RF信号响应于由应答器检测到的由蜂窝状物质产生的电信号进行调制。沟槽电极可以植入外周神经中，用于治疗各种神经疾病，其可以包括神经康复和假体致动，严重的疼痛，阻塞性睡眠呼吸暂停等。

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