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1. 发明申请

US20130022684A1 ORAL PHARMACEUTICAL COMPOSITION COMPRISING FENOFIBRIC ACID AND AN ALKALIFYING AGENT 审中-公开
标题翻译：含有抗坏血酸和碱性化合物的口服药物组合物
公开(公告)号：US20130022684A1
公开(公告)日：2013-01-24
申请号：US13637530
申请日：2011-04-12
申请人： Ki Young Jang , Mijin Park , Kyeong Soo Kim , Yong Il Kim , Jae Hyun Park , Jong Soo Woo
发明人： Ki Young Jang , Mijin Park , Kyeong Soo Kim , Yong Il Kim , Jae Hyun Park , Jong Soo Woo
IPC分类号： A61K9/14 , A61K9/20 , B29B9/12 , A61K31/192 , A61K9/00
CPC分类号： A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/5026 , A61K9/5042 , A61K9/5047 , A61K31/192
摘要： An oral pharmaceutical composition of the present invention comprising fenofibric acid or a pharmaceutically acceptable salt thereof, and 0.22 to 1 part by weight of an alkalifying agent based on 1 part by weight of fenofibric acid has improved bioavailability and a minimized absorption deviation in the gastrointestinal tract, which is useful in treating hyperlipidemia and hypertriglyceridemia.
摘要翻译：包含非诺贝酸或其药学上可接受的盐的本发明的口服药物组合物和基于1重量份非诺贝酸的0.22至1重量份的碱化剂具有改善的生物利用度和最小化的胃肠道吸收偏差，其可用于治疗高脂血症和高甘油三酯血症。

2. 发明申请

US20120110957A1 METHOD FOR PREPARING RAPIDLY DISINTEGRATING FORMULATION FOR ORAL ADMINISTRATION 审中-公开
标题翻译：制备口服药物快速消毒配方的方法
公开(公告)号：US20120110957A1
公开(公告)日：2012-05-10
申请号：US13343879
申请日：2012-01-05
申请人： Chang Hyun LEE , Jong Soo Woo , Hong Gi Yi , Kyeong Soo Kim , Ho Taek Yim
发明人： Chang Hyun LEE , Jong Soo Woo , Hong Gi Yi , Kyeong Soo Kim , Ho Taek Yim
IPC分类号： B65B63/08
CPC分类号： A61K9/0056 , A61J3/10 , A61K9/2095 , B30B11/02 , B30B11/08 , B65B9/042 , B65B9/045
摘要： A method and packaging machine for preparing rapidly disintegrating formulations for oral administration are disclosed. The present invention is characterized in that a powdery mixture including a pharmaceutically active ingredient and a sugar or a sugar alcohol powder is filled into a packaging material and, thereafter, the mixture, filled in the packaging material, is heated. The present invention can simply and economically prepare an oral formulation which undergoes rapid disintegration in the oral cavity and provides for high-quality administration to patients.
摘要翻译：公开了用于制备用于口服给药的快速崩解制剂的方法和包装机。本发明的特征在于将包含药物活性成分和糖或糖醇粉末的粉末混合物填充到包装材料中，然后将填充在包装材料中的混合物加热。本发明可以简单且经济地制备在口腔中快速崩解并提供给患者高质量给药的口服制剂。

3. 发明申请

US20110245301A1 SOLID PHARMACEUTICAL COMPOSITION COMPRISING AMLODIPINE AND LOSARTAN WITH IMPROVED STABILITY 有权
标题翻译：包含具有改善稳定性的阿片和洛沙坦的固体药物组合物
公开(公告)号：US20110245301A1
公开(公告)日：2011-10-06
申请号：US13139426
申请日：2009-06-05
申请人： Jae Hyun Park , Kyeong Soo Kim , Ho Taek Yim , Ji Hyun Im
发明人： Jae Hyun Park , Kyeong Soo Kim , Ho Taek Yim , Ji Hyun Im
IPC分类号： A61K31/44 , A61P9/00 , A61P9/12 , A61P9/04
CPC分类号： A61K31/41 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/5084 , A61K31/4178 , A61K31/44 , A61K31/4422 , A61K2300/00
摘要： The present invention relates to a solid pharmaceutical composition for preventing or treating cardiovascular disorders comprising granular forms of amlodipine and losartan which are separated from each other, and a stabilizing agent, which has improved storage stability due to minimized interaction between amlodipine and losartan.
摘要翻译：本发明涉及用于预防或治疗心血管疾病的固体药物组合物，其包含彼此分离的氨氯地平和氯沙坦的颗粒形式，以及由于氨氯地平与氯沙坦之间的相互作用最小化而具有改善的储存稳定性的稳定剂。

4. 发明授权

US06359885B1 Multi-channel packet switching apparatus having traffic flow controlling and checking functions 失效
标题翻译：具有业务流控制和检查功能的多信道分组交换设备
公开(公告)号：US06359885B1
公开(公告)日：2002-03-19
申请号：US09138310
申请日：1998-08-21
申请人： Keun Bae Kim , Paul S. Min , Kyeong-Soo Kim , Otto Schmid
发明人： Keun Bae Kim , Paul S. Min , Kyeong-Soo Kim , Otto Schmid
IPC分类号： H04L1256
CPC分类号： H04L47/29 , H04L45/38 , H04L47/10 , H04L47/26
摘要： A multi-channel packet switching apparatus having traffic flow controlling and checking functions which is capable of simply controlling the system and having a simpler construction by concurrently performing a cell copy function and a cell routing function for providing a multi-casting function. The apparatus includes a synchronizing unit for synchronizing the cells recirculated through the recirculation link with the cells newly inputted into the routing unit based on time and providing to the routing unit, a reverse direction flow control requesting unit for counting the number of cells which are recirculated at every cell time and requesting a reverse direction flow control to a traffic providing source when the thusly counted number exceeds a threshold value, a reverse direction buffering control unit for restricting a cell output to the output port through which a request signal is outputted when a reverse direction flow control request signal is received from the traffic receiving source until the request signal is released, an error cell removing unit for removing an error cell based on the routing tag error among the cells from the bypass link by the routing unit within a predetermined time, and a cell loss counting unit for counting the cell loss which are not recirculated by the recirculation path setting unit by the input port.
摘要翻译：一种具有业务流控制和检查功能的多信道分组交换设备，其能够简单地控制系统并且通过同时执行小区复制功能和用于提供多播功能的小区路由功能具有更简单的结构。该装置包括：同步单元，用于基于时间将再循环链路再循环的单元与新输入到路由单元中的单元同步，并向路由单元提供反向流控制请求单元，用于对再循环的单元数进行计数在每个小区时间，并且当这样计数的数量超过阈值时向流量提供源请求反向流量控制;反向缓冲控制单元，用于将小区输出限制到输出端口，通过该输出端口输出请求信号从业务接收源接收到逆向流量控制请求信号，直到请求信号被释放为止，在预定的路由单元内，基于来自旁路链路的小区中的路由标签错误去除错误小区的差错小区删除单元时间，以及用于计数不再循环的细胞损失的细胞损失计数单元由再循环路径设定单元由输入端口填充。

5. 发明授权

US5859846A Fully-interconnected asynchronous transfer mode switching apparatus 失效
标题翻译：全互联异步传输模式切换装置
公开(公告)号：US5859846A
公开(公告)日：1999-01-12
申请号：US685527
申请日：1996-07-24
申请人： Kyeong Soo Kim , Hyup Jong Kim
发明人： Kyeong Soo Kim , Hyup Jong Kim
IPC分类号： H04Q3/00 , H04L12/931 , H04Q11/04 , H04L12/56
CPC分类号： H04L12/5601 , H04L49/101 , H04L49/106 , H04L49/1584 , H04L49/3081 , H04Q11/0478 , H04L2012/5605 , H04L2012/5626 , H04L2012/5674 , H04L49/253
摘要： A fully-interconnected ATM switching apparatus comprising a plurality of line interface circuits, each of the line interface circuits including an input port driver for extracting an SDH transmission frame containing cell data with a fixed length and a connection identifier from an input signal, appending a routing tag to the extracted SDH transmission frame and outputting the resultant SDH transmission frame through an input dedicated bus and an output port driver for receiving a cell stream from an output dedicated bus, removing the routing tag from the received cell stream, translating a channel identifier in the connection identifier and transferring the resultant SDH transmission frame to an adjacent node, a system clock distributor for generating a clock signal, an initialization controller for controlling system initialization and restart operations, a switch maintenance controller for performing a switch maintenance control operation in response to a network managing cell, a switch call processing controller for performing a call processing operation, a switch module controller for controlling a switching operation, and a plurality of switch output multiplexers for switching cells from the input port drivers to the output port drivers under the control of the switch module controller.
摘要翻译：一种完全互连的ATM交换设备，包括多个线路接口电路，每个线路接口电路包括用于从输入信号中提取包含固定长度的小区数据和连接标识符的SDH传输帧的输入端口驱动器，路由标签到所提取的SDH传输帧，并通过输入专用总线输出所得到的SDH传输帧，以及用于从输出专用总线接收信元流的输出端口驱动器，从接收的信元流中移除路由标签，翻译信道标识符在连接标识符中并将所得到的SDH传输帧传送到相邻节点，用于产生时钟信号的系统时钟分配器，用于控制系统初始化和重新启动操作的初始化控制器，响应于执行开关维护控制操作的开关维护控制器到网络管理单元，用于执行呼叫处理操作的瘙痒呼叫处理控制器，用于控制切换操作的开关模块控制器，以及用于在开关模块控制器的控制下将单元从输入端口驱动器切换到输出端口驱动器的多个开关输出多路复用器。

6. 发明授权

US5732085A Fixed length packet switching apparatus using multiplexers and demultiplexers 失效
标题翻译：使用多路复用器和解复用器的固定长度分组交换设备
公开(公告)号：US5732085A
公开(公告)日：1998-03-24
申请号：US573093
申请日：1995-12-15
申请人： Kyeong Soo Kim , Hyup Jong Kim , Keun Bae Kim , Jeong Jin Lee
发明人： Kyeong Soo Kim , Hyup Jong Kim , Keun Bae Kim , Jeong Jin Lee
IPC分类号： H04Q11/04 , H04J3/24 , H04L12/70 , H04L12/931 , H04L12/937 , H04J3/26 , H04L12/56
CPC分类号： H04L12/5601 , H04J3/247 , H04L49/106 , H04L49/3081 , H04L2012/5672 , H04L2012/5681 , H04L2012/5684
摘要： The present invention relates to a fixed length packet switching apparatus using multiplexers and demultiplexers in which the apparatus has an output buffer-type construction, protects itself from a temporary overflow occurrence of an output terminal and has the construction of the mutual flow control to enhance its entire performance. The present invention can protect the entire operations as well as enhance the entire performance of the switching apparatus by preventing an obstacle of the switching apparatus due to an overflow temporarily generated from an output terminal, process without a loss of excessive cells a traffic phenomenon of one output port in the switching apparatus, reduce the necessary buffer according to the effect of the rate gain and process smoothly input traffic of the internal buffer having a burst characteristic. Further more, the present invention has a duplicate function of cells able to provide a broadcast-type service distributed to subscribers at one time so that the subscribers can receive a distributed service to thereby increase the effectiveness of the channel.
摘要翻译：本发明涉及一种使用多路复用器和解复用器的固定长度分组交换设备，其中该设备具有输出缓冲型结构，保护自身免受输出终端的暂时溢出的影响，并且具有相互流控制的结构以增强其整体表现。本发明可以通过防止由于从输出端暂时产生的溢出而导致的开关装置的障碍物来提高整个操作的整体性能，而不会损失过多的电池一个交通现象输出端口，根据速率增益的影响减少必要的缓冲器，并处理具有突发特性的内部缓冲器的平滑输入业务。此外，本发明具有能够一次提供分配给用户的广播型服务的小区的重复功能，使得用户可以接收分布式服务，从而增加频道的有效性。

7. 发明申请

US20140112962A1 PHARMACEUTICAL COMPOSITION COMPRISING AMIDE DERIVATIVE INHIBITING THE GROWTH OF CANCER CELLS AND NON-METALLIC SALT LUBRICANT 有权
标题翻译：包含酰胺衍生物抑制癌细胞和非金属盐润滑剂生长的药物组合物
公开(公告)号：US20140112962A1
公开(公告)日：2014-04-24
申请号：US14124436
申请日：2012-05-18
申请人： Yong Il Kim , Kyeong Soo Kim , Jin Cheul Kim , Yo Han Kim , Jae Hyun Park , Jong Soo Woo
发明人： Yong Il Kim , Kyeong Soo Kim , Jin Cheul Kim , Yo Han Kim , Jae Hyun Park , Jong Soo Woo
IPC分类号： A61K47/44 , A61K47/26 , A61K47/10 , A61K47/14 , A61K47/02 , A61K47/36 , A61K31/517 , A61K47/12
CPC分类号： A61K47/44 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2031 , A61K9/2077 , A61K31/517 , A61K47/02 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/36 , C07D401/12
摘要： Disclosed is a pharmaceutical composition comprising an amide derivative or a pharmaceutically acceptable salt thereof and a non-metallic salt lubricant, which can be used as an effective cancer cell-growth inhibitor owing to its enhanced storage stability with no quality changes over time.
摘要翻译：公开了一种药物组合物，其包含其酰胺衍生物或其药学上可接受的盐和非金属盐润滑剂，其可以用作有效的癌细胞生长抑制剂，这是由于其增强的储存稳定性而随时间而没有质量变化。

8. 发明授权

US08673945B2 Solid pharmaceutical composition comprising amlodipine and losartan 有权
标题翻译：包含氨氯地平和氯沙坦的固体药物组合物
公开(公告)号：US08673945B2
公开(公告)日：2014-03-18
申请号：US13140348
申请日：2009-12-28
申请人： Jong Soo Woo , Jae Hyun Park , Young Il Kim , Kyeong Soo Kim , Ho Taek Yim , Ji Hyun Im
发明人： Jong Soo Woo , Jae Hyun Park , Young Il Kim , Kyeong Soo Kim , Ho Taek Yim , Ji Hyun Im
IPC分类号： A61K31/41 , A61K31/44
CPC分类号： A61K31/41 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/5084 , A61K31/4178 , A61K31/44 , A61K31/4422 , A61K2300/00
摘要： The present invention relates to a solid pharmaceutical composition for preventing or treating cardiovascular disorders comprising amlodipine and losartan as active ingredients, and a disintegrant which is a mixture of at least two components selected from the group consisting of sodium starch glycolate, crosscarmellose sodium, and crosspovidone, which exhibits a high and stable level of amlodipine and losartan dissolution rates.
摘要翻译：本发明涉及一种用于预防或治疗包含氨氯地平和氯沙坦作为活性成分的心血管疾病的固体药物组合物，和崩解剂，其是选自淀粉羟乙酸钠，交联羧甲基纤维素钠和交联聚维酮的至少两种组分的混合物，其表现出高且稳定的氨氯地平和氯沙坦溶出速率水平。

9. 发明授权

US06980519B1 Multi-table based grant generator for improved granularity in an ATM-PON 有权
标题翻译：基于多表的授权生成器，用于改进ATM-PON中的粒度
公开(公告)号：US06980519B1
公开(公告)日：2005-12-27
申请号：US09616408
申请日：2000-07-14
申请人： David N Horn , Kyeong-Soo Kim , J H J Maessen
发明人： David N Horn , Kyeong-Soo Kim , J H J Maessen
IPC分类号： H04L12/44 , H04L12/56 , G01R31/08
CPC分类号： H04Q11/0067 , H04L12/5602 , H04L2012/5605 , H04L2012/561 , H04L2012/5615 , H04L2012/5679 , H04Q2011/0064
摘要： A multi-table-based grant generator in accordance with the present invention solves the issue of bandwidth granularity, while maintaining the simplicity of a table approach. The present invention grant generator provides grants of fine granularity for regulation of upstream transmission of cells in an ATM PON. Multiple grant tables having differing bandwidth granularities are linked together through a simple grant distribution mechanism. The grant tables and grant distribution mechanisms can be recursively linked to achieve a number of different granularities. The grant generator of the present invention is based on multiple grant tables with a combination of multiplexers, dividers, and address counters. The grant generator provides both larger and smaller bandwidths for data grants as well as PLOAM grants without large size grant tables. In one exemplary embodiment of the present invention, improved granularity is achieved, where a first grant table is used for one size of bandwidth grant, e.g., data grants, and the second grant table is used for another size of bandwidth grant, e.g., low bandwidth data grants as well as PLOAM grants. A simple clock divider couples to each of the grant tables through corresponding address counters. The clock divider provides a set number of bandwidth grants from each table over a complete cycle. The clock divider also selects an appropriate input port of a multiplexer through which the grants from each grant table are respectively transmitted. By having the ability to issue variable sized bandwidth grants, the granularity is significantly improved, thereby translating to a more efficient use of the bandwidth. More specifically, grants of a finer granularity can be issued without the need for an excessively large grant table usually thought to be necessary to produce fine granularities.
摘要翻译：根据本发明的基于多表的授权生成器解决了带宽粒度的问题，同时保持了表方法的简单性。本发明的授权生成器提供用于调整ATM PON中的小区的上行传输的细粒度的准许。具有不同带宽粒度的多个授权表通过简单的授权分配机制链接在一起。授权表和授权分配机制可以递归链接以实现多个不同的粒度。本发明的授权生成器基于具有多路复用器，分频器和地址计数器的组合的多个授权表。授权生成器为数据授予提供较大和较小的带宽以及无大容量授权表的PLOAM授权。在本发明的一个示例性实施例中，实现了改进的粒度，其中第一授权表用于一个大小的带宽授权，例如数据许可，并且第二许可表用于另一大小的带宽授权，例如低带宽数据授权以及PLOAM资助。简单的时钟分频器通过相应的地址计数器耦合到每个授权表。时钟分频器在一个完整的周期内提供每个表的一组数量的带宽授权。时钟分频器还选择分配了来自每个授权表的授权的多路复用器的适当输入端口。通过具有发布可变大小的带宽授权的能力，显着提高了粒度，从而转化为更有效地使用带宽。更具体地，可以发出更细粒度的授予，而不需要通常被认为是产生细粒度所必需的过大的授权表。

10. 发明授权

US06771908B2 Fast protection switching by snooping on downstream signals in an optical network 有权
标题翻译：通过窥探光网络中的下行信号进行快速保护切换
公开(公告)号：US06771908B2
公开(公告)日：2004-08-03
申请号：US09781863
申请日：2001-02-12
申请人： Peter Van Eijk , Reed K. Even , Piet Van Heyningen , Song Jiang , Kyeong-Soo Kim , Woojune Kim , Fengkun Liu , Yong-Kwan Park
发明人： Peter Van Eijk , Reed K. Even , Piet Van Heyningen , Song Jiang , Kyeong-Soo Kim , Woojune Kim , Fengkun Liu , Yong-Kwan Park
IPC分类号： H04B1008
CPC分类号： H04J14/0291 , H04B10/032 , H04B10/272 , H04J3/0682 , H04J14/0282 , H04Q11/0066 , H04Q11/0067 , H04Q2011/0079 , H04Q2011/0081 , H04Q2011/0083
摘要： An optical network has an optical splitter connected to (1) a working optical subscriber unit (OSU) of a working circuit, (2) a protection OSU of a protection circuit, and (3) one or more optical network terminals (ONTs), where an ONT has (i) a working line termination (LT) unit of the working circuit and connected to the optical splitter via a working optical fiber and (ii) a protection LT unit of the protection circuit and connected to the optical splitter via a protection optical fiber. The present invention enables fast protection switching from the working circuit to the protection circuit. The arrival times of corresponding downstream cells are measured at both the working and protection LT units of the ONT, and information related to the arrival times is transmitted from the ONT to the protection OSU. A propagation delay value is generated based on the transmitted information for use by the protection OSU for communications with the ONT if and when protection switching is implemented upon detection of a failure in the working circuit.
摘要翻译：光网络具有连接到（1）工作电路的工作光用户单元（OSU）的光分路器，（2）保护电路的保护OSU，以及（3）一个或多个光网络终端（ONT）其中ONT具有（i）工作电路的工作线路终端（LT）单元，并且经由工作光纤连接到分光器，以及（ii）保护电路的保护LT单元，并经由保护光纤。本发明能够从工作电路到保护电路的快速保护切换。在ONT的工作和保护LT单元上测量相应下游单元的到达时间，并且与ONT相关的信息从ONT发送到保护OSU。如果在检测到工作电路中的故障时实现保护切换，则基于被保护OSU用于与ONT通信的传输信息生成传播延迟值。

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