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1. 发明申请

US20100254510A1 APPARATUS FOR DIAGNOSING BREAST CANCER BY NESTED FILTERS COATED MULTILAYER 审中-公开
标题翻译：用于通过涂覆多层膜过滤器诊断乳腺癌的装置
公开(公告)号：US20100254510A1
公开(公告)日：2010-10-07
申请号：US12280294
申请日：2006-02-21
申请人： Kwon-Ha Yoon , Kwon-Soo Cheon
发明人： Kwon-Ha Yoon , Kwon-Soo Cheon
IPC分类号： A61B6/04 , A61B6/00
CPC分类号： A61B6/4042 , A61B6/06 , A61B6/4233 , A61B6/4441 , A61B6/502
摘要： Provided is a breast cancer diagnosing apparatus using an X-ray, in which the breast cancer diagnosing apparatus selects and uses energy within a specific band width through an energy band pass filter. In the breast cancer diagnosing apparatus, a multilayer filter unit having one or more layers of a basic filter having a multilayer structure is inserted between an X-ray generator and a breast fixing unit having a paddle fixing the breast so as to allow a predetermined band of an X-ray spectrum generated from the X-ray generator to pass therethrough and be emitted to the breast. According to the present invention, the X-ray dosage of the patient by energy within a low energy band (8-15 keV) can be reduced 5 times as compared with that by the conventional apparatus.
摘要翻译：提供了一种使用X射线的乳腺癌诊断装置，其中乳腺癌诊断装置通过能带通滤波器选择并使用特定带宽内的能量。在乳腺癌诊断装置中，将具有一层以上具有多层结构的碱性过滤器的多层过滤器单元插入到具有固定乳房的桨的X射线发生器和乳房定影单元之间，以允许预定的带由X射线发生器产生的X射线光谱通过并发射到乳房。根据本发明，与传统装置相比，能量在低能带（8-15keV）内的能量的X射线剂量可以减少5倍。

2. 发明申请

US20100074848A1 X-ray contrast agent using gold nanoparticles and process for preparing the same 审中-公开
标题翻译：使用金纳米颗粒的X射线造影剂及其制备方法
公开(公告)号：US20100074848A1
公开(公告)日：2010-03-25
申请号：US12300336
申请日：2006-08-31
申请人： Kwon-ha Yoon
发明人： Kwon-ha Yoon
IPC分类号： A61K49/04
CPC分类号： A61K49/0428 , B82Y5/00 , C08G65/334
摘要： Provided are an X-ray contrast agent using gold nanoparticles and a process for preparing the X-ray contrast agent. The X-ray contrast agent is prepared by capping gold nanoparticles with polyethylene glycol (PEG). The X-ray contrast agent is nontoxic and remains in a blood vessel for a long time so that the X-ray contrast agent can be usefully used as a computed tomography (CT) contrast agent for imaging blood vessels. Therefore, the X-ray contrast agent is useful for inspecting blood vessel structures and new blood vessels in a tumor, and obtaining perfusion images. In addition, gold provides better visibility than iodine when used in an X-ray contrast agent. Therefore, better x-ray images can be obtained using the X-ray contrast agent containing gold nanoparticles.
摘要翻译：提供了使用金纳米颗粒的X射线造影剂和制备X射线造影剂的方法。通过用聚乙二醇（PEG）覆盖金纳米颗粒制备X射线造影剂。 X射线造影剂是无毒的并且长时间保留在血管中，使得X射线造影剂可有效地用作用于血管成像的计算机断层摄影（CT）造影剂。因此，X射线造影剂可用于检查肿瘤中的血管结构和新血管，并获得灌注图像。此外，当用于X射线造影剂时，金提供比碘更好的可见性。因此，可以使用含有金纳米颗粒的X射线造影剂获得更好的X射线图像。

3. 发明申请

US20070053487A1 Soft X-ray microscope 失效
标题翻译：软X射线显微镜
公开(公告)号：US20070053487A1
公开(公告)日：2007-03-08
申请号：US11510615
申请日：2006-08-28
申请人： Kwon-ha Yoon , Kyong-woo Kim
发明人： Kwon-ha Yoon , Kyong-woo Kim
IPC分类号： G21K7/00
CPC分类号： G21K7/00 , G21K2201/06 , H05G2/008
摘要： A soft X-ray microscope includes a table (10); a housing (20) installed to the upper side of the table (10) and having a partition (22); a light source chamber (30) installed lower than the partition (22) of the housing (20) to project a light to liquid jetted under a high pressure to generate plasma; a mirror chamber (40), installed above the partition (22) of the housing (20), in which first and second mirror (410 and 430) are respectively installed to upper and lower sides of a holder (420) for storing a living sample, the soft X-ray generated by the plasma generated in the light source chamber (30) illuminates the living sample, and the soft X-ray penetrated the living sample is amplified to obtain an image in an image capturing chamber; and an image capturing chamber (50) installed to the upper side of the housing (20) to amplify a light image signal amplified through the mirror chamber (40) and to capture the light image on an external screen to allow distinguishing the light image from exterior.
摘要翻译：软X射线显微镜包括台（10）; 安装在所述工作台（10）的上侧并具有隔板（22）的壳体（20）; 光源室（30），其安装在所述壳体（20）的隔板（22）的下方，以将在高压下喷射的液体投射到液体中以产生等离子体; 安装在所述壳体（20）的隔板（22）上方的反射镜室（40），其中第一和第二反射镜（410和430）分别安装在用于储存活体的保持器（420）的上侧和下侧样品中，由光源室（30）中产生的等离子体产生的软X射线照射活体样品，并且穿透活体样品的软X射线被放大，以在摄像室中获得图像; 以及安装到所述壳体（20）的上侧的图像捕获室（50），用于放大通过所述镜室（40）放大的光图像信号，并将所述光图像捕获到外部屏幕上以允许将所述光图像与外观。

4. 发明申请

US20110158379A1 COMPUTED TOMOGRAPHY SYSTEM HAVING NANO-SPATIAL RESOLUTION 审中-公开
标题翻译：具有纳米空间分辨率的计算机图像系统
公开(公告)号：US20110158379A1
公开(公告)日：2011-06-30
申请号：US12647323
申请日：2009-12-24
申请人： Kwon-Soo CHEON , Kwon Ha Yoon
发明人： Kwon-Soo CHEON , Kwon Ha Yoon
IPC分类号： H05G1/60
CPC分类号： G21K1/06 , G21K1/067 , G21K7/00
摘要： Provide is a computed tomography (CT) system having a nano-spatial resolution. The computed tomography system can obtain a 3-dimensional image having the nano-spatial resolution of less than about 100 nm from a 2-dimension image generated by limiting a thickness of a bio sample such as cells and micro-tissues or an industrial solid sample such as a semiconductor chip to a thickness of less than about 100 μm, enlarging an X-ray transmitting the sample to a high magnification of greater than about 100× using a diffractive optic having a magnification of greater than about 100× such as a zone plate, and condensing the X-ray. When the CT system having the nano-spatial resolution is used, the 3-dimensional image having the nano-spatial resolution of less than about 100 nm may be obtained from the bio sample and industrial solid sample having a thickness of less than about 100 μm that is not observed using a conventional CT system including a cone-shaped light source unit. Therefore, an internal structure (an internal short-circuit of a semiconductor chip) of the sample may be very easily detected.
摘要翻译：提供是具有纳米空间分辨率的计算机断层摄影（CT）系统。计算机断层摄影系统可以从通过限制诸如细胞和微组织或工业固体样品的生物样品的厚度产生的二维图像获得具有小于约100nm的纳米空间分辨率的三维图像例如厚度小于约100μm的半导体芯片，使用具有大于约100×的放大倍率的衍射光学器件扩大将样品透射到大于约100×的高倍率的X射线，例如区域平板，并冷凝X射线。当使用具有纳米空间分辨率的CT系统时，具有小于约100nm的纳米空间分辨率的三维图像可以从厚度小于约100μm的生物样品和工业固体样品获得使用包括锥形光源单元的常规CT系统未观察到。因此，可以非常容易地检测出样品的内部结构（半导体芯片的内部短路）。

5. 发明申请

US20080089472A1 Dual-radiation type mammography apparatus and breast imaging method using the mammography apparatus 审中-公开
标题翻译：双辐射型乳房摄影装置和使用乳房摄影装置的乳房成像方法
公开(公告)号：US20080089472A1
公开(公告)日：2008-04-17
申请号：US11902756
申请日：2007-09-25
申请人： Kwon-Ha Yoon
发明人： Kwon-Ha Yoon
IPC分类号： A61B6/04
CPC分类号： A61B6/482 , A61B6/4035 , A61B6/502
摘要： A dual-radiation type mammography apparatus for examining a breast by taking a breast image using x-ray beams is provided. The mammography apparatus includes an x-ray generating unit generating the x-ray beams, a first collimator provided with transmission holes through which a solid angle beam generated from the x-ray beams radiated from the x-ray generating unit, in the course of which the solid angle beam is changed into a plurality of beams each having a predetermined size, a plurality of multi-layered filter units that filters off some of the beams passing through the holes of the first collimator to deflect only beams in a first specific energy band, a breast fixing unit fixing the breast B that will be scanned by the beams deflected by the multi-layered filter units, and a plurality of image output units provided for the respective beams scanning the breast fixed by the breast fixing unit and reforming two-dimensional images formed by the beams deflected at different angles into a three-dimensional image.
摘要翻译：提供了一种通过使用X射线束拍摄乳房图像来检查乳房的双照射型乳房摄影装置。乳房摄影装置包括产生x射线束的X射线产生单元，设置有透射孔的第一准直仪，从X射线产生单元辐射的X射线束产生的立体角光束通过该透射孔在其中立体角光束被改变成每个具有预定尺寸的多个光束;多个多层滤光器单元，其滤除通过第一准直仪的孔的一些光束，以仅使光束以第一比能量偏转固定胸部B的乳房定影单元，其将被由多层过滤器单元偏转的光束扫描;以及多个图像输出单元，其设置用于扫描由乳房固定单元固定的乳房的各个梁，并重整两个由以不同角度偏转成三维图像的光束形成的三维图像。

6. 发明授权

US07474729B2 Soft X-ray microscope 失效
标题翻译：软X射线显微镜
公开(公告)号：US07474729B2
公开(公告)日：2009-01-06
申请号：US11510615
申请日：2006-08-28
申请人： Kwon-ha Yoon , Kyong-woo Kim
发明人： Kwon-ha Yoon , Kyong-woo Kim
IPC分类号： G21K7/00
CPC分类号： G21K7/00 , G21K2201/06 , H05G2/008
摘要： A soft X-ray microscope includes a table (10); a housing (20) installed to the upper side of the table (10) and having a partition (22); a light source chamber (30) installed lower than the partition (22) of the housing (20) to project a light to liquid jetted under a high pressure to generate plasma; a mirror chamber (40), installed above the partition (22) of the housing (20), in which first and second mirror (410 and 430) are respectively installed to upper and lower sides of a holder (420) for storing a living sample, the soft X-ray generated by the plasma generated in the light source chamber (30) illuminates the living sample, and the soft X-ray penetrated the living sample is amplified to obtain an image in an image capturing chamber; and an image capturing chamber (50) installed to the upper side of the housing (20) to amplify a light image signal amplified through the mirror chamber (40) and to capture the light image on an external screen to allow distinguishing the light image from exterior.
摘要翻译：软X射线显微镜包括台（10）; 安装在所述工作台（10）的上侧并具有隔板（22）的壳体（20）; 光源室（30），其安装在所述壳体（20）的隔板（22）的下方，以将在高压下喷射的液体投射到液体中以产生等离子体; 安装在所述壳体（20）的隔板（22）上方的反射镜室（40），其中第一和第二反射镜（410和430）分别安装在用于储存活体的保持器（420）的上侧和下侧样品中，由光源室（30）中产生的等离子体产生的软X射线照射活体样品，并且穿透活体样品的软X射线被放大，以在摄像室中获得图像; 以及安装到所述壳体（20）的上侧的图像捕获室（50），以放大通过所述镜室（40）放大的光图像信号，并将所述光图像捕获到外部屏幕上以允许将所述光图像与外观。

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