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    • 2. 发明申请
    • SPECTRAL DECONVOLUTION IN ION CYCLOTRON RESONANCE MASS SPECTROMETRY
    • 离子循环共振质谱分析中的光谱分解
    • US20110251801A1
    • 2011-10-13
    • US12755977
    • 2010-04-07
    • Alexander MISHARINKonstantin NovoselovVladimir M. Doroshenko
    • Alexander MISHARINKonstantin NovoselovVladimir M. Doroshenko
    • G06F19/00H01J49/26
    • H01J49/0036H01J49/38
    • A method and system for deconvolution of a frequency spectrum obtained in an ICR mass spectrometer based on a detection of ion oscillation overtones of the M-th order (where the integer M>1). A plurality of frequency peaks is collected within the frequency spectrum corresponding respectively to oscillations of different groups of ions, and associates at least one of the frequency peaks having a frequency f and a measured amplitude A with a particular group of the ions. The method and system identify whether the frequency peak is related to one of an overtone frequency, a subharmonic frequency, a higher harmonic frequency, or a side-shifted frequency of the oscillations of the different group of ions. The method and system derive calculated amplitudes of the overtone frequency peaks associated with the groups of ions by incorporating measured amplitudes of the frequency peaks related to the subharmonic frequency, the higher harmonic frequency, or the side-shifted frequency associated with the groups of ions into the calculated amplitudes of the overtone frequency peaks. The method and system generate a deconvoluted frequency spectrum including the overtone frequency peaks associated with the different groups of ions.
    • 基于对M阶离子振荡泛音(其中整数M> 1)的检测,在ICR质谱仪中获得的频谱的去卷积方法和系统。 在分别对应于不同离子组的振荡的频谱内收集多个频率峰值,并且将具有频率f和测量幅度A的频率峰值中的至少一个与特定的一组离子相关联。 该方法和系统识别频率峰值是否与不同离子组的振荡的泛音频率,次谐波频率,高次谐波频率或侧移频率之一相关。 该方法和系统通过将与次谐波频率,高次谐波频率或与离子组相关联的侧移频率相关的频率峰值的测量幅度并入到离子组相关的泛音频率峰值中来计算振幅 计算的泛音频率峰值的幅度。 该方法和系统产生包括与不同离子组相关的泛音频率峰值的解卷积频谱。
    • 5. 发明授权
    • Spectral deconvolution in ion cyclotron resonance mass spectrometry
    • 离子回旋共振质谱中的光谱去卷积
    • US08825413B2
    • 2014-09-02
    • US12755977
    • 2010-04-07
    • Alexander MisharinKonstantin NovoselovVladimir M. Doroshenko
    • Alexander MisharinKonstantin NovoselovVladimir M. Doroshenko
    • G01N31/00H01J49/38H01J49/00H03F1/26
    • H01J49/0036H01J49/38
    • A method and system for deconvolution of a frequency spectrum obtained in an ICR mass spectrometer based on a detection of ion oscillation overtones of the M-th order (where the integer M>1). A plurality of frequency peaks is collected within the frequency spectrum corresponding respectively to oscillations of different groups of ions, and associates at least one of the frequency peaks having a frequency f and a measured amplitude A with a particular group of the ions. The method and system identify whether the frequency peak is related to one of an overtone frequency, a subharmonic frequency, a higher harmonic frequency, or a side-shifted frequency of the oscillations of the different group of ions. The method and system derive calculated amplitudes of the overtone frequency peaks associated with the groups of ions by incorporating measured amplitudes of the frequency peaks related to the subharmonic frequency, the higher harmonic frequency, or the side-shifted frequency associated with the groups of ions into the calculated amplitudes of the overtone frequency peaks. The method and system generate a deconvoluted frequency spectrum including the overtone frequency peaks associated with the different groups of ions.
    • 基于对M阶离子振荡泛音(其中整数M> 1)的检测,在ICR质谱仪中获得的频谱的去卷积方法和系统。 在分别对应于不同离子组的振荡的频谱内收集多个频率峰值,并且将具有频率f和测量幅度A的频率峰值中的至少一个与特定的一组离子相关联。 该方法和系统识别频率峰值是否与不同离子组的振荡的泛音频率,次谐波频率,高次谐波频率或侧移频率之一相关。 该方法和系统通过将与次谐波频率,高次谐波频率或与离子组相关联的侧移频率相关的频率峰值的测量幅度并入到离子组相关的泛音频率峰值中来计算振幅 计算的泛音频率峰值的幅度。 该方法和系统产生包括与不同离子组相关的泛音频率峰值的解卷积频谱。