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1. 发明授权

US06706020B1 Syringes and injectors incorporating magnetic fluid agitation devices 失效
标题翻译：掺入磁性流体搅拌装置的注射器和注射器
公开(公告)号：US06706020B1
公开(公告)日：2004-03-16
申请号：US09763647
申请日：2001-04-19
申请人： Klaus Urich
发明人： Klaus Urich
IPC分类号： A61M5315
CPC分类号： A61M5/14546 , A61M1/0204 , A61M5/14566 , B01F13/08
摘要： A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. The agitation element is acted on by a magnetic field to agitate the contents of the syringe. The magnetic field is generated by a source operably associated with the syringe or the injector. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.
摘要翻译：用于注射器的注射器包括主体，其包括远端排出端，可移动地设置在主体内的柱塞，以及设置在柱塞和远侧排出端之间的主体内的搅动元件。搅拌元件通过磁场作用以搅动注射器的内容物。磁场由与注射器或注射器可操作地相关联的源产生。优选地，注射器包含由搅拌元件搅动的超声造影剂。还提供了一种用于搅拌注射器内容物的注射器系统和方法。

2. 发明授权

US06471674B1 Fluid delivery systems, injector systems and methods of fluid delivery 有权
标题翻译：流体输送系统，注射器系统和流体输送方法
公开(公告)号：US06471674B1
公开(公告)日：2002-10-29
申请号：US09553822
申请日：2000-04-21
申请人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
发明人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
IPC分类号： A61M3700
CPC分类号： A61M5/1407 , A61M5/007 , A61M5/16827 , A61M39/26 , Y10S128/01
摘要： A fluid delivery system for delivery of an injection fluid to a patient generally includes a pump system to pressurize the injection fluid, a patient interface in removable fluid connection with the pump system, and a connector in fluid connection between the pump system and the patient interface. The pump system is connected to an inlet of the connector, and the patient interface is removably connected to an outlet of the connector. The connector includes a sealing member at least partly disposed within a housing of the connector that is biased to close the outlet when the patient interface is removed.
摘要翻译：用于将注射流体输送到患者的流体递送系统通常包括泵系统以对注射流体加压，与泵系统可移动流体连接的患者接口，以及在泵系统和患者接口之间的流体连接的连接器。泵系统连接到连接器的入口，患者接口可移除地连接到连接器的出口。所述连接器包括至少部分地设置在所述连接器的壳体内的密封构件，当所述患者接口被移除时，所述密封构件被偏置以关闭所述出口。

3. 发明申请

US20120330152A1 FLUID MANAGEMENT SYSTEM 有权
标题翻译：流体管理系统
公开(公告)号：US20120330152A1
公开(公告)日：2012-12-27
申请号：US13512565
申请日：2009-11-24
申请人： Claus-Peter Reisinger , Klaus Urich , Matthias Burg , Andreas Kalitzki , Samantha Anne Patterson , Kathryn Anne Louise Farrell , Andrew Murray Gow , Scott Alexander Lewis , Mark Jeffrey Edhouse
发明人： Claus-Peter Reisinger , Klaus Urich , Matthias Burg , Andreas Kalitzki , Samantha Anne Patterson , Kathryn Anne Louise Farrell , Andrew Murray Gow , Scott Alexander Lewis , Mark Jeffrey Edhouse
IPC分类号： A61B6/00 , A61M5/00
CPC分类号： A61M5/16827 , A61M5/007 , A61M5/1407 , A61M5/1413 , A61M5/1414
摘要： The fluid management system according to the invention is adapted to automatically supply fluid for injection into a patient. The fluid management system comprises a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi dose containers. The fluid transfer system connects the outlet of the containers stored within the fluid management device to the injector and the injector withdraws the fluid via fluid transfer system from the containers and injects the fluid to an administration device at the patient. The fluid management device comprises at least one rotating carousel with the axis of rotation being vertically, at least two container holders attached to the rotating carousel, said container holders being adapted to position a container vertically with the open end of the neck facing downwards and a spike holder mounted below the rotating carousel and oriented such that the spike holder would axially align a spike connected to the spike holder with the axis of the container that is to be spiked and loaded into the container holder.
摘要翻译：根据本发明的流体管理系统适于自动地向患者提供用于注射的流体。流体管理系统包括流体管理装置，流体输送系统和流体注射器。流体管理装置用于存储和管理多剂量容器。流体传送系统将存储在流体管理装置内的容器的出口连接到注射器，并且喷射器通过流体传送系统从容器中取出流体，并将流体注射到患者处的给药装置。所述流体管理装置包括至少一个旋转圆盘传送带，其旋转轴线是垂直的，至少两个容器保持器附接到旋转的圆盘传送带上，所述容器保持器适于将容器垂直定位，颈部的开口端面向下，尖头保持器安装在旋转的圆盘传送器下方并且定向成使得尖钉保持器将与尖头保持器连接的尖峰轴向对准待加标注并容纳到容器保持器中的容器的轴线。

4. 发明授权

US06972001B2 Fluid delivery system having pump systems, check valves and a removable patient interface 有权
标题翻译：流体输送系统具有泵系统，止回阀和可移除的患者接口
公开(公告)号：US06972001B2
公开(公告)日：2005-12-06
申请号：US10790299
申请日：2004-03-01
申请人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
发明人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
IPC分类号： A61M5/00 , A61M5/14 , A61M5/168 , A61M39/26 , A61M37/00
CPC分类号： A61M5/1407 , A61M5/007 , A61M5/16827 , A61M39/26 , Y10S128/01
摘要： A fluid delivery system for delivery of an injection fluid to a patient generally includes a first pump system, a second pump system, a patient interface in removable fluid connection with the first and second pump systems, and a fluid path in fluid connection between the first and second pump systems and the patient interface. The fluid path preferably includes a housing member defining a first inlet, a second inlet and an outlet. The first and second pump systems are placed in fluid connection with the respective first and second inlets of the housing member and the patient interface is placed in removable fluid connection with the outlet of the housing member. A first check valve is in fluid connection between an outlet of the first pump system and the first inlet of the housing member, and a second check valve is in fluid connection between an outlet of the second pump system and the second inlet of the housing member.
摘要翻译：用于将注射流体输送到患者的流体递送系统通常包括第一泵系统，第二泵系统，与第一和第二泵系统可移动流体连接的患者接口，以及在第一和第二泵系统之间流体连接的流体路径和第二泵系统和患者接口。流体路径优选地包括限定第一入口，第二入口和出口的壳体构件。第一和第二泵系统被放置成与壳体构件的相应的第一和第二入口流体连接，并且患者接口被放置成与壳体构件的出口可移动的流体连接。第一止回阀在第一泵系统的出口和壳体构件的第一入口之间流体连接，并且第二止回阀在第二泵系统的出口和壳体构件的第二入口之间流体连接。

5. 发明授权

US09162026B2 Injector system 有权
标题翻译：注射器系统
公开(公告)号：US09162026B2
公开(公告)日：2015-10-20
申请号：US13512548
申请日：2010-11-24
申请人： Matthias Burg , Klaus Urich
发明人： Matthias Burg , Klaus Urich
IPC分类号： A61M5/142 , A61M5/168 , G06F19/00
CPC分类号： A61M5/14212 , A61M5/16827 , A61M2205/6018 , A61M2205/6054 , G06F19/00 , G06F19/3468
摘要： The present disclosure relates to a pump injector containing a processor, a pump or a motor with advance for a piston which is suitable for driving liquid out of a container or a cartridge, a data storage device, and a device for data transfer, wherein the processor is electronically connected to the data storage device, to a control unit for the pump or motor, and to the device for data transfer. The injector is suitable for being connected to a container or a cartridge for fluid transfer, which contains a multiplicity of doses of a parenteral solution and has an additional data storage device fixedly connected thereto. The device for data transfer is suitable for reading out information from the additional data storage device on the container including at least one specification in respect to the identity of the product stored in the container or in the cartridge is stored in the container, a maximum dose per patient, and a maximum usage period after opening the container.
摘要翻译：本公开涉及一种泵喷射器，其包含处理器，泵或马达，其具有用于活塞的推进器，该活塞适合于将液体从容器或墨盒驱出，数据存储装置和用于数据传输的装置，其中，处理器电连接到数据存储设备，连接到泵或电机的控制单元，以及用于数据传输的设备。注射器适于连接到用于流体转移的容器或药筒，其包含多个剂量的肠胃外溶液，并且具有与其固定连接的附加数据存储装置。用于数据传输的装置适于从容器上的附加数据存储装置读出信息，其中包括关于存储在容器中的产品的身份或存储在容器中的盒中的至少一个规格，最大剂量每个患者和打开容器后的最大使用期限。

6. 发明授权

US09555189B2 Fluid management device having rotating carousel with container holders for vertically positioning a container during automated spiking and injection into patient 有权
标题翻译：流体管理装置具有带有容器保持器的旋转转盘，用于在自动加注和注入患者期间垂直定位容器
公开(公告)号：US09555189B2
公开(公告)日：2017-01-31
申请号：US13512565
申请日：2010-11-24
申请人： Claus-Peter Reisinger , Klaus Urich , Matthias Burg , Andreas Kalitzki , Samantha Anne Patterson , Kathryn Anne Louise Farrell , Andrew Murray Gow , Scott Alexander Lewis , Mark Jeffrey Edhouse
发明人： Claus-Peter Reisinger , Klaus Urich , Matthias Burg , Andreas Kalitzki , Samantha Anne Patterson , Kathryn Anne Louise Farrell , Andrew Murray Gow , Scott Alexander Lewis , Mark Jeffrey Edhouse
IPC分类号： B65B1/36 , A61M5/168 , B67B7/04 , A61M5/00 , A61M5/14
CPC分类号： A61M5/16827 , A61M5/007 , A61M5/1407 , A61M5/1413 , A61M5/1414
摘要： A fluid management system adapted to automatically supply fluid for injection into a patient is disclosed. The fluid management system includes a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi-dose containers. The fluid transfer system connects an outlet of these containers to the injector which withdraws a fluid from the containers via the fluid transfer system and injects the fluid to an administration device at the patient. The fluid management device includes at least one rotating carousel having a vertical axis of rotation, at least two container holders attached to the rotating carousel and adapted to position the container vertically with a septum covered end facing downwards, and a spike holder mounted below the rotating carousel and oriented so the spike holder axially aligns a spike connected to the spike holder with the axis of the container.
摘要翻译：公开了一种流体管理系统，其适于自动地将流体注入患者体内。流体管理系统包括流体管理装置，流体输送系统和流体注射器。流体管理装置用于存储和管理多剂量容器。流体传输系统将这些容器的出口连接到注射器，该注射器通过流体传送系统从容器中抽出流体，并将流体注射到患者处的给药装置。流体管理装置包括至少一个具有垂直旋转轴线的旋转圆盘传送器，至少两个容器保持器，其附接到旋转的圆盘传送带，并且适于将容器垂直地定位，其中隔膜覆盖的端部面向下，以及安装在旋转圆盘传送带并且定向成使得尖钉保持器轴向对准连接到钉座的钉与容器的轴线。

7. 发明授权

US06855103B2 Radioactive implantable devices and methods and apparatuses for their production and use 失效
标题翻译：放射性植入装置及其生产和使用的方法和装置
公开(公告)号：US06855103B2
公开(公告)日：2005-02-15
申请号：US10217379
申请日：2002-08-13
申请人： Ludger Dinkelborg , Klaus Urich
发明人： Ludger Dinkelborg , Klaus Urich
IPC分类号： A61B17/00 , A61F2/00 , A61K51/00 , A61K51/12 , A61M36/04 , A61N5/10 , C23G1/08 , C25D5/10 , C25D7/00 , C25D7/04 , C25D17/12 , C25F3/00 , A61N5/00
CPC分类号： A61K51/1282 , A61F2210/0095 , A61N5/1002
摘要： A radiolabeled implantable device includes a base, a first layer including Cu and a radioactive isotope on the base, and a second layer including Sn on the first layer. Preferably, the base is formed of stainless steel and the radioactive isotope is a radioisotope of Re, such as 188Re or 186Re. Alternately, radioisotopes of the following elements may be used: Be, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, As, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, In, Sn, Sb, Te, Hf, Ta, W, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Po, At, Th, Pa, U, Np, Pu, Am, Cm, Bk, Cf, Es, Fm, Md, No, Lr. In addition, a process for producing a radiolabeled implantable device includes depositing a first layer including Cu and a radioactive isotope on a base, and depositing a second layer including Sn on the first layer. The process may further include removing Cr2O3 from the base and/or rinsing the base prior to depositing the first layer thereon.
摘要翻译：放射性标记的可植入装置包括基底，在基底上包括Cu和放射性同位素的第一层和在第一层上包含Sn的第二层。优选地，基底由不锈钢形成，并且放射性同位素是Re的放射性同位素，例如<188> Re或<186> Re。或者，可以使用以下元素的放射性同位素：Be，Sc，Ti，V，Cr，Mn，Fe，Co，Ni，Cu，Zn，Ga，Ge，As，Y，Zr，Nb，Mo，Tc，Ru ，Rh，Pd，Ag，Cd，In，Sn，Sb，Te，Hf，Ta，W，Os，Ir，Pt，Au，Hg，Tl，Pb，Bi，Po，At，Th，Pa，U，Np ，Pu，Am，Cm，Bk，Cf，Es，Fm，Md，No，Lr。此外，生产放射性标记的可植入装置的方法包括在基底上沉积包含Cu和放射性同位素的第一层，并在第一层上沉积包含Sn的第二层。该方法还可以包括在沉积第一层之前从基底中除去Cr 2 O 3和/或漂洗基底。

8. 发明授权

US06699219B2 Fluid delivery systems, injector systems and methods of fluid delivery 有权
标题翻译：流体输送系统，注射器系统和流体输送方法
公开(公告)号：US06699219B2
公开(公告)日：2004-03-02
申请号：US10281661
申请日：2002-10-28
申请人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
发明人： Michael F. Emig , Klaus Urich , Frederick Trombley, III , Joseph B. Havrilla , Edward J. Rhinehart , Gerald W. Callan
IPC分类号： A61M3700
CPC分类号： A61M5/1407 , A61M5/007 , A61M5/16827 , A61M39/26 , Y10S128/01
摘要： A fluid delivery system for delivery of an injection fluid to a patient generally includes a pump system to pressurize the injection fluid, a patient interface in removable fluid connection with the pump system, and a connector in fluid connection between the pump system and the patient interface. The pump system is connected to an inlet of the connector, and the patient interface is removably connected to an outlet of the connector. The connector includes a sealing member at least partly disposed within a housing of the connector that is biased to close the outlet when the patient interface is removed.
摘要翻译：用于将注射流体输送到患者的流体递送系统通常包括泵系统以对注射流体加压，与泵系统可移动流体连接的患者接口，以及在泵系统和患者接口之间的流体连接的连接器。泵系统连接到连接器的入口，患者接口可移除地连接到连接器的出口。所述连接器包括至少部分地设置在所述连接器的壳体内的密封构件，当所述患者接口被移除时，所述密封构件被偏置以关闭所述出口。

9. 发明申请

US20120316435A1 INJECTOR SYSTEM 有权
标题翻译：喷油器系统
公开(公告)号：US20120316435A1
公开(公告)日：2012-12-13
申请号：US13512548
申请日：2010-11-24
申请人： Matthias Burg , Klaus Urich
发明人： Matthias Burg , Klaus Urich
IPC分类号： A61M5/20 , A61B6/00
CPC分类号： A61M5/14212 , A61M5/16827 , A61M2205/6018 , A61M2205/6054 , G06F19/00 , G06F19/3468
摘要： The present disclosure relates to an injector containing a processor, a pump or a motor with advance for a piston, which is suitable for driving liquid out of a cartridge, a data storage device, a device for data transfer, wherein the processor is electronically connected to the data storage device, to a control unit for the pump or the motor, and to the device for data transfer; wherein the injector is suitable for being connected to a container or a cartridge for fluid transfer, which container or cartridge contains a multiplicity of doses of a parenteral solution; wherein a data storage device is fixedly connected to the container or the cartridge; wherein the device for data transfer is suitable for reading out information from the data storage device on the container or the cartridge; and wherein at least one specification in respect of the identity of the product stored in the container or in the cartridge is stored in the data storage device on the container or the cartridge. The disclosure furthermore relates to a container or a cartridge, which contains a multiplicity of doses of a parenteral solution, wherein a data storage device is fixedly connected to the container or the cartridge.
摘要翻译：本公开涉及一种包含处理器，泵或电动机的喷射器，其具有用于活塞的前进，其适合于将液体从盒中驱出，数据存储装置，用于数据传送的装置，其中处理器电连接到数据存储装置，用于泵或电动机的控制单元，以及用于数据传送的装置; 其中所述注射器适于连接到用于流体转移的容器或药筒，所述容器或药筒包含多种剂量的肠胃外溶液; 其中数据存储装置固定地连接到所述容器或所述盒; 其中用于数据传送的装置适于从容器或盒上的数据存储装置中读出信息; 并且其中关于存储在所述容器中或所述盒中的产品的身份的至少一个规范被存储在所述容器或所述盒上的所述数据存储装置中。此外，本公开涉及容纳多个剂量的肠胃外溶液的容器或药筒，其中数据存储装置固定地连接到容器或药筒。

10. 发明授权

US06966894B1 Syringes and injectors incorporating mechanical fluid agitation devices 失效
标题翻译：注射器和注射器结合机械流体搅拌装置
公开(公告)号：US06966894B1
公开(公告)日：2005-11-22
申请号：US09763646
申请日：1999-08-26
申请人： Klaus Urich
发明人： Klaus Urich
IPC分类号： A61M5/142 , A61M1/02 , A61M5/145 , B01F11/00 , B01F13/00 , A61M37/00 , A61M5/00 , A61M5/315 , A61M31/00
CPC分类号： B01F13/005 , A61M1/0204 , A61M5/14546 , B01F11/0002 , B01F11/0017 , B01F11/0022 , B01F13/0052 , B01F2003/0035
摘要： A syringe for use with an injector includes a body comprising a distal discharge end, a plunger movably disposed within the body, and an agitation element disposed within the body between the plunger and the distal discharge end. A movement mechanism is operably associated with the injector to move the syringe in such a way that the at least one agitation element agitates a fluid contained in the syringe. Preferably, the syringe contains an ultrasound contrast agent that is agitated by the agitation element. An injector system and a method for agitating the contents of a syringe are also provided.
摘要翻译：用于注射器的注射器包括主体，其包括远端排出端，可移动地设置在主体内的柱塞，以及设置在柱塞和远侧排出端之间的主体内的搅动元件。移动机构与注射器可操作地相关联以使注射器以使得至少一个搅动元件搅动包含在注射器中的流体的方式移动。优选地，注射器包含由搅拌元件搅动的超声造影剂。还提供了一种用于搅拌注射器内容物的注射器系统和方法。

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