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1. 发明申请

US20100310053A1 X-RAY IRRADIATOR 有权
标题翻译： X射线辐射器
公开(公告)号：US20100310053A1
公开(公告)日：2010-12-09
申请号：US12734717
申请日：2009-03-03
申请人： Keiichiro Yamamoto
发明人： Keiichiro Yamamoto
IPC分类号： H05G1/06
CPC分类号： H05G1/06 , H01J35/025 , H05G1/10
摘要： Provided is an X-ray irradiator which reduces the occurrence of discharge resulting from the difference in electric potential in the X-ray irradiator, and which concurrently achieves reduction in size and weight. In an X-ray irradiator (1), an X-ray tube (11) and a high-voltage generator (2) are installed inside a casing (18), and an insulation oil (13) is filled in the casing (18). The high-voltage generator (2) is configured by arranging and electrically connecting together multiple ring-shaped voltage amplifying units (21). An anode (14) and a cathode (15) of the X-ray tube (11) are fitted in and thus installed in hollow portions of the voltage amplifying units (21).
摘要翻译：本发明提供一种能够减少由X射线照射装置的电位差引起的放电发生的X射线照射装置，能够同时实现小型化和轻量化。在X射线照射器（1）中，将X射线管（11）和高压发生器（2）安装在壳体（18）内，绝缘油（13）填充在壳体（18））。高电压发生器（2）通过将多个环形电压放大单元（21）布置并电连接在一起而构成。 X射线管（11）的阳极（14）和阴极（15）嵌入并安装在电压放大单元（21）的中空部分。

2. 发明授权

US06247495B1 Flow rate detection mechanism with a restriction element for mass flow meters 有权
标题翻译：具有质量流量计限制元件的流量检测机构
公开(公告)号：US06247495B1
公开(公告)日：2001-06-19
申请号：US09452636
申请日：1999-12-01
申请人： Keiichiro Yamamoto , Yoshihiro Taniguchi
发明人： Keiichiro Yamamoto , Yoshihiro Taniguchi
IPC分类号： G01F500
CPC分类号： G01F5/00 , G01F1/684 , Y10T137/7761 , Y10T137/87354 , Y10T137/87539
摘要： A flow proportioning assembly for dividing a portion of a fluid flow such as gas for presentation to a sensor includes a holder member having a central opening and forming an exterior peripheral passageway when inserted within a conduit of a flow meter housing. A resistor member can be adjustably mounted in the central opening downstream of a holder member aperture to encourage a laminar flow pattern and a large entrance port and a large exit port can communicate with a passageway that is operatively connected with a sensor. The exit port is downstream of the resistor member. Flexible fastener members can engage the resistor member and the holder member for ease of mounting. The resistor member can also comprise a helical arrangement of small fluid passageways to encourage laminar flow.
摘要翻译：用于将诸如用于呈现的气体的流体流的一部分分割成传感器的流量比例组合件包括具有中心开口的保持器构件，并且当插入到流量计壳体的管道内时形成外部周边通道。电阻器构件可以可调节地安装在保持器构件孔的下游的中央开口中，以促进层流图案，并且大的入口和大的出口可与与传感器可操作地连接的通道连通。出口在电阻构件的下游。柔性紧固件可以与电阻件和保持件接合，以方便安装。电阻器构件还可以包括小的流体通道的螺旋排列以促进层流。

3. 发明申请

US20130114794A1 X-Ray Generation Device 有权
标题翻译： X射线发生装置
公开(公告)号：US20130114794A1
公开(公告)日：2013-05-09
申请号：US13810597
申请日：2011-07-11
申请人： Keiichiro Yamamoto
发明人： Keiichiro Yamamoto
IPC分类号： H01J35/16
CPC分类号： H05G1/06 , H05G1/025
摘要： Provided is an X-ray generation device including an X-ray tube and a high-voltage generation unit arranged inside a housing and also having insulating oil filled in the housing, which uses no lead and is small in size, thereby achieving a reduction in manufacturing cost, and which also has high cooling performance. An X-ray generation device 1 includes an X-ray tube 2 and a high-voltage generation unit 3 inside a housing 8 and also has insulating oil 4 filled in the housing 8, the X-ray tube 2 being configured to generate an X ray, the X-ray generation device 1 characterized in that the X-ray tube 2 is arranged inside an X-ray tube holder 10, a material of the X-ray tube holder 10 contains at least bismuth oxide and a resin, and the X-ray tube holder 10 includes an opening and a plurality of slits 11, the opening being provided in a portion corresponding to an X-ray irradiation window 7 through which the X-ray tube 2 applies the X ray, the slits 11 allowing the insulating oil 4 to circulate between an inside and an outside of the X-ray tube holder 10.
摘要翻译：本发明提供一种X射线产生装置，其包括配置在壳体内部的X射线管和高压发生单元，并且还具有填充在壳体中的绝缘油，其不使用铅并且尺寸小，从而实现制造成本，并且还具有高冷却性能。 X射线产生装置1包括在壳体8内的X射线管2和高压发生单元3，并且还具有填充在壳体8中的绝缘油4，X射线管2被配置为产生X X射线产生装置1的特征在于，X射线管2配置在X射线管保持架10的内部，X射线管保持架10的材料至少含有氧化铋和树脂， X射线管支架10包括开口和多个狭缝11，该开口设置在与X射线管2施加X射线的X射线照射窗口7相对应的部分中，狭缝11允许绝缘油4在X射线管保持器10的内部和外部之间循环。

4. 发明授权

US08331533B2 X-ray irradiator 有权
标题翻译： X射线照射器
公开(公告)号：US08331533B2
公开(公告)日：2012-12-11
申请号：US12734717
申请日：2009-03-03
申请人： Keiichiro Yamamoto
发明人： Keiichiro Yamamoto
IPC分类号： H05G1/10
CPC分类号： H05G1/06 , H01J35/025 , H05G1/10
摘要： Provided is an X-ray irradiator which reduces the occurrence of discharge resulting from the difference in electric potential in the X-ray irradiator, and which concurrently achieves reduction in size and weight. In an X-ray irradiator (1), an X-ray tube (11) and a high-voltage generator (2) are installed inside a casing (18), and an insulation oil (13) is filled in the casing (18). The high-voltage generator (2) is configured by arranging and electrically connecting together multiple ring-shaped voltage amplifying units (21). An anode (14) and a cathode (15) of the X-ray tube (11) are fitted in and thus installed in hollow portions of the voltage amplifying units (21).
摘要翻译：本发明提供一种能够减少由X射线照射装置的电位差引起的放电发生的X射线照射装置，能够同时实现小型化和轻量化。在X射线照射器（1）中，将X射线管（11）和高压发生器（2）安装在壳体（18）内，绝缘油（13）填充在壳体（18））。高电压发生器（2）通过将多个环形电压放大单元（21）布置并电连接在一起而构成。 X射线管（11）的阳极（14）和阴极（15）嵌入并安装在电压放大单元（21）的中空部分。

5. 发明申请

US20100029849A1 HIGH MOLECULAR WEIGHT DERIVATIVE OF NUCLEIC ACID ANTIMETABOLITE 有权
标题翻译：高分子量重量的核酸抗微生物剂
公开(公告)号：US20100029849A1
公开(公告)日：2010-02-04
申请号：US12312157
申请日：2007-11-06
申请人： Keiichiro Yamamoto , Kazutoshi Takashio
发明人： Keiichiro Yamamoto , Kazutoshi Takashio
IPC分类号： C08F287/00
CPC分类号： A61K31/787 , A61K47/60 , A61K47/645 , C08G69/42 , C08G69/48 , C08G73/028
摘要： [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a higher therapeutic effect at a lower dose.[Means for Solving Problems] Disclosed is a high molecular weight derivative a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the nucleoside derivative is bound to the carboxyl group in the side chain of the high molecular weight compound via a highly hydrophobic linker.
摘要翻译： [问题]需要核酸抗代谢物的衍生物，其可以在较低剂量下显示更高的治疗效果。解决问题的手段公开了一种核酸抗代谢产物的高分子量衍生物，其特征在于包含包含聚乙二醇部分和侧链中具有羧基的聚合物部分的高分子量化合物和核苷衍生物，可以作为核酸抗代谢物，其中核苷衍生物通过高度疏水的接头与高分子量化合物的侧链中的羧基结合。

6. 发明申请

US20080156236A1 PULVERIZED COAL COMBUSTION BOILER 审中-公开
标题翻译：粉煤燃烧锅炉
公开(公告)号：US20080156236A1
公开(公告)日：2008-07-03
申请号：US11958763
申请日：2007-12-18
申请人： Osamu Ito , Masayuki Taniguchi , Hironobu Kobayashi , Keiichiro Yamamoto , Yoshio Shimogori , Teruyuki Okazaki , Kenji Kiyama
发明人： Osamu Ito , Masayuki Taniguchi , Hironobu Kobayashi , Keiichiro Yamamoto , Yoshio Shimogori , Teruyuki Okazaki , Kenji Kiyama
IPC分类号： F23D1/00 , F23K3/00
CPC分类号： F23D1/00 , F23C6/047 , F23M5/08
摘要： A pulverized coal combustion boiler 100 comprising: a furnace 50; a plurality of burners 6 for supplying and burning pulverized coal fuel in the furnace arranged at positions of a plurality of stages having different heights on a furnace front wall 51 and a furnace rear wall 52 of furnace wall surfaces forming the furnace 50, the furnace rear wall 52 arranged for facing the furnace front wall 51; a plurality of mills 2 arranged for supplying the pulverized coal fuel to the plurality of burners 6 arranged at each of the plurality of stages; and pulverized fuel pipes 5 arranged for distributing and supplying the pulverized coal to the plurality of burners 6 at each of the stages of the furnace front wall 51 and the furnace rear wall 52 from each of the plurality of mills 2.
摘要翻译：一种粉煤燃烧锅炉100，包括：炉50; 多个燃烧器6，用于在炉壁前壁51和炉后壁52上形成炉子50的炉后表面上设置多个不同高度位置的炉子中的粉煤燃料，炉后方布置成面向炉前壁51的壁52; 多个研磨机2，其设置用于将粉煤燃料供给到布置在多个阶段中的多个燃烧器6; 以及粉碎燃料管5，其布置成从多个轧机2的炉前壁51和炉后壁52的每个阶段向多个燃烧器6分配和供应粉煤。

7. 发明授权

US08188222B2 High molecular weight derivative of nucleic acid antimetabolite 有权
标题翻译：核酸抗代谢物的高分子量衍生物
公开(公告)号：US08188222B2
公开(公告)日：2012-05-29
申请号：US12312157
申请日：2007-11-06
申请人： Keiichiro Yamamoto , Kazutoshi Takashio
发明人： Keiichiro Yamamoto , Kazutoshi Takashio
IPC分类号： C07K5/037 , C07H19/06 , C07H19/067 , C07H19/073 , C07H19/09 , C07H19/16 , C07H19/167 , C07H19/173 , C07H19/19 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K31/708 , A61K38/06 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/16
CPC分类号： A61K31/787 , A61K47/60 , A61K47/645 , C08G69/42 , C08G69/48 , C08G73/028
摘要： [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a higher therapeutic effect at a lower dose.[Means for Solving Problems] Disclosed is a high molecular weight derivative a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the nucleoside derivative is bound to the carboxyl group in the side chain of the high molecular weight compound via a highly hydrophobic linker.
摘要翻译： [问题]需要核酸抗代谢物的衍生物，其可以在较低剂量下显示更高的治疗效果。解决问题的手段公开了一种核酸抗代谢产物的高分子量衍生物，其特征在于包含包含聚乙二醇部分和侧链中具有羧基的聚合物部分的高分子量化合物和核苷衍生物，可以作为核酸抗代谢物，其中核苷衍生物通过高度疏水的接头与高分子量化合物的侧链中的羧基结合。

8. 发明申请

US20090281300A1 HIGH-MOLECULAR WEIGHT DERIVATIVE OF NUCLEIC ACID ANTIMETABOLITE 有权
标题翻译：高分子重量衍生物的核酸抗微生物剂
公开(公告)号：US20090281300A1
公开(公告)日：2009-11-12
申请号：US12312009
申请日：2007-11-01
申请人： Keiichiro Yamamoto , Kazutoshi Takashio
发明人： Keiichiro Yamamoto , Kazutoshi Takashio
IPC分类号： C07H19/06
CPC分类号： A61K31/787 , A61K47/60 , A61K47/645 , C08G69/10 , C08G69/40 , C08G69/48
摘要： [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a high therapeutic effect at a low dose.[Means For Solving Problems] Disclosed is a high molecular weight derivative of a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the carboxyl group in the side chain is bound to a hydroxyl group in the nucleoside derivative via an ester bond. Also disclosed is a method for producing the high molecular weight derivative.
摘要翻译： [问题]需要可以在低剂量下显示高治疗效果的核酸抗代谢物的衍生物。解决问题的手段公开了核酸抗代谢物的高分子量衍生物，其特征在于包含高分子量化合物，其包含聚乙二醇部分和在侧链具有羧基的聚合物部分和核苷衍生物其可以作为核酸抗代谢物，其中侧链中的羧基通过酯键与核苷衍生物中的羟基结合。还公开了高分子量衍生物的制造方法。

9. 发明申请

US20080039468A1 Novel 3-Phenyltetrahydrocinnolin-5-Ol Derivative and Medicinal Use Thereof 审中-公开
标题翻译：新型3-苯基四氢喔啉-5-醇衍生物及其药物用途
公开(公告)号：US20080039468A1
公开(公告)日：2008-02-14
申请号：US11597232
申请日：2005-06-08
申请人： Yoshitaka Sato , Yoshikazu Suzuki , Keiichiro Yamamoto , Shunsuke Kuroiwa , Sakiko Maruyama
发明人： Yoshitaka Sato , Yoshikazu Suzuki , Keiichiro Yamamoto , Shunsuke Kuroiwa , Sakiko Maruyama
IPC分类号： A61K31/502 , A61P35/00 , C07D237/28
CPC分类号： C07D237/28
摘要： A 3-phenyltetrahydrocinnolin-5-ol derivative represented by the following general formula (1) (wherein Z represents 2-carboxyethyl, 3-dimethylaminopropyl etc.; X represents trifluoromethyl etc.; X′ represents hydrogen, etc.; and Y anti Y′ each represents methyl, hydrogen, etc.), a physiologically acceptable salt thereof, or a prodrug of either. They have cytostatic activity against tumor cells and hence are effective as an antitumor agent.
摘要翻译：由以下通式（1）表示的3-苯基四氢噌啉-5-醇衍生物（其中Z表示2-羧乙基，3-二甲基氨基丙基等; X表示三氟甲基等; X'表示氢等; Y抗Y “各自表示甲基，氢等等），其生理上可接受的盐，或其前体药物。它们对肿瘤细胞具有细胞抑制活性，因此作为抗肿瘤剂是有效的。

10. 发明授权

US08517607B2 X-ray generation device 有权
标题翻译： X射线发生装置
公开(公告)号：US08517607B2
公开(公告)日：2013-08-27
申请号：US13810597
申请日：2011-07-11
申请人： Keiichiro Yamamoto
发明人： Keiichiro Yamamoto
IPC分类号： H01J35/16
CPC分类号： H05G1/06 , H05G1/025
摘要： Provided is an X-ray generation device including an X-ray tube and a high-voltage generation unit arranged inside a housing and also having insulating oil filled in the housing, which uses no lead and is small in size, thereby achieving a reduction in manufacturing cost, and which also has high cooling performance. An X-ray generation device 1 includes an X-ray tube 2 and a high-voltage generation unit 3 inside a housing 8 and also has insulating oil 4 filled in the housing 8, the X-ray tube 2 being configured to generate an X ray, the X-ray generation device 1 characterized in that the X-ray tube 2 is arranged inside an X-ray tube holder 10, a material of the X-ray tube holder 10 contains at least bismuth oxide and a resin, and the X-ray tube holder 10 includes an opening and a plurality of slits 11, the opening being provided in a portion corresponding to an X-ray irradiation window 7 through which the X-ray tube 2 applies the X ray, the slits 11 allowing the insulating oil 4 to circulate between an inside and an outside of the X-ray tube holder 10.
摘要翻译：本发明提供一种X射线产生装置，其包括配置在壳体内部的X射线管和高压发生单元，并且还具有填充在壳体中的绝缘油，其不使用铅并且尺寸小，从而实现制造成本，并且还具有高冷却性能。 X射线产生装置1包括在壳体8内的X射线管2和高压发生单元3，并且还具有填充在壳体8中的绝缘油4，X射线管2被配置为产生X X射线产生装置1的特征在于，X射线管2配置在X射线管保持架10的内部，X射线管保持架10的材料至少含有氧化铋和树脂， X射线管支架10包括开口和多个狭缝11，该开口设置在与X射线管2施加X射线的X射线照射窗口7相对应的部分中，狭缝11允许绝缘油4在X射线管保持器10的内部和外部之间循环。

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