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    • 1. 发明申请
    • IMMUNOCHROMATOGRAPHIC MEDIUM AND IMMUNOCHROMATOGRAPHIC METHOD
    • 免疫组织化学和免疫组织化学方法
    • US20110244597A1
    • 2011-10-06
    • US13130884
    • 2009-11-19
    • Kazuya TsukadaTsuneko Fujii
    • Kazuya TsukadaTsuneko Fujii
    • G01N33/543
    • G01N33/558B82Y5/00G01N33/582
    • Disclosed are an immunochromatographic medium and an immunochromatographic method in which, even when plural items exceeding four items are detected which are the number of colors that can be detected by colored latex particles, the plural items can be detected and quantified simultaneously. The immunochromatographic medium comprises a support, a label-attached reagent immobilized on a labeling agent, and detection portions on which a material capable of combining with a substance to be detected in a sample is immobilized, the label-attached reagent and the detection portions being provided on the support, featured in that the labeling agent is a phosphor nanoparticle and the detection portions are shaped in the form of dots.
    • 公开了免疫色谱介质和免疫色谱法,其中即使检测到超过四个项目的多个项目是可以由着色胶乳颗粒检测的颜色数量,也可以同时检测和量化多个项目。 免疫色谱介质包含载体,固定在标记试剂上的标记附着试剂和固定有能够与待检测物质组合的材料的检测部分,标记试剂和检测部分为 其特征在于,标记剂是荧光体纳米颗粒,并且检测部分以点的形式成形。
    • 3. 发明申请
    • LABELING FLUORESCENT COMPOUND
    • 标签荧光化合物
    • US20100044673A1
    • 2010-02-25
    • US12531092
    • 2008-03-26
    • Kazuya TsukadaKazuyoshi GoanHisatake Okada
    • Kazuya TsukadaKazuyoshi GoanHisatake Okada
    • H01L33/00G01N33/58C09K11/08
    • C09K9/02B82Y30/00G01N21/64G01N33/587Y10T428/2991
    • A labeling fluorescent compound which enables highly stable detection in vital labeling and has high sensitivity. The labeling fluorescent compound is characterized by being composed of inorganic fluorescent nanoparticles which have a surface modification compound disposed on the surface thereof and have an average particle diameter of 1.0-20 nm. It is further characterized in that the proportion of the length of the surface modification compound as measured from the surface of the inorganic fluorescent nanoparticles to the particle diameter of the inorganic fluorescent nanoparticles is from 0.10 to 0.50, and that the proportion of the specific gravity of the inorganic fluorescent nanoparticles having the surface modification compound fixed thereto to the specific gravity of the inorganic fluorescent nanoparticles not having the surface modification compound is from 0.80 to 0.40.
    • 标记荧光化合物,能够在生物标记中进行高度稳定的检测并具有高灵敏度。 标记荧光化合物的特征在于由其表面上设置有平均粒径为1.0〜20nm的表面改性化合物的无机荧光纳米粒子构成。 其特征在于,从无机荧光纳米粒子的表面测定的表面改性化合物的长度与无机荧光纳米粒子的粒径的比例为0.10〜0.50,并且比重 具有固定有表面改性化合物的无机荧光纳米颗粒的比重为不具有表面改性化合物的无机荧光纳米粒子的比重为0.80〜0.40。
    • 8. 发明授权
    • Surface defect test method and surface defect tester
    • 表面缺陷测试方法和表面缺陷测试仪
    • US5898491A
    • 1999-04-27
    • US49015
    • 1998-03-27
    • Takayuki IshiguroIzuo HoraiKazuya Tsukada
    • Takayuki IshiguroIzuo HoraiKazuya Tsukada
    • G01N21/93G01N21/95H01L21/66H01L23/544G01N21/88
    • H01L22/34G01N21/93G01N21/9501H01L22/12
    • The surface defect test method and tester according to the invention comprises a sensitivity calibration disk formed with n (n is an integer equal to or larger than 2) false defect rows each including 3 or more false defects each formed in a radial or peripheral direction provided in the peripheral direction of the calibration disk at a predetermined angle pitch. The false defects of each false defect row take in the form of protrusions or recesses having substantially the same size, adjacent ones of the false defects are physically separated by a predetermined distance larger than a width of a laser spot and the false defects of a certain one of the false defect rows are different in size from the false defects of other false defect rows, regulating the detection sensitivity according to a result of the test, producing, from a result of a test of the calibration disk with the regulated detection sensitivity, data relating a level of a detection signal to a size of the false defect as a reference data for determination of the size and obtaining the size of the defect from the level of the detection signal when the disk to be tested on defect on the basis of the reference data for determination of the size.
    • 根据本发明的表面缺陷测试方法和测试仪包括形成有n(n是等于或大于2的整数)的灵敏度校准盘,每个包含3个或更多个假的缺陷行,每个虚假缺陷各自形成在径向或周向上提供 在校准盘的圆周方向上以预定的角度间距。 每个假缺陷行的假缺陷采取具有基本相同尺寸的突起或凹槽的形式,相邻的假缺陷在物理上分开大于激光斑的宽度的预定距离,并且一定的假缺陷 假缺陷行中的一个与其他错误缺陷行的假缺陷大小不同,根据测试结果调节检测灵敏度,从具有调节检测灵敏度的校准盘的测试结果, 将检测信号的电平与虚假缺陷的大小相关联的数据作为参考数据,用于确定尺寸并根据检测信号的电平获得缺陷的大小,当基于 用于确定尺寸的参考数据。
    • 9. 发明授权
    • Sensitivity calibration disk for surface defect tester
    • 表面缺陷测试仪的灵敏度校准盘
    • US5875027A
    • 1999-02-23
    • US048993
    • 1998-03-27
    • Takayuki IshiguroIzuo HoraiKazuya Tsukada
    • Takayuki IshiguroIzuo HoraiKazuya Tsukada
    • G01N21/88G11B5/84G01J1/02
    • G11B5/84G01N21/88
    • A calibration disk for calibrating a sensitivity of a surface defect tester, according to the present invention, comprises n (n is an integer equal to or larger than 2) false defect rows each including 3 or more false defects each formed in a radial or peripheral direction provided in the peripheral direction of the calibration disk at a predetermined angle pitch. The false defects of each false defect row take in the form of protrusions or recesses having substantially the same size, adjacent ones of the false defects are physically separated by a predetermined distance larger than a width of a laser spot and the false defects of a certain one of the false defect rows are different in size from the false defects of other false defect rows.
    • 根据本发明的用于校准表面缺陷测试器的灵敏度的校准盘包括n(n是等于或大于2的整数)的假缺陷行,每个包括3个或更多个在径向或周边形成的假缺陷 方向以预定的角度间距设置在校准盘的圆周方向上。 每个假缺陷行的假缺陷采取具有基本相同尺寸的突起或凹槽的形式,相邻的假缺陷在物理上分开大于激光斑的宽度的预定距离,并且一定的假缺陷 其中一个虚假缺陷行的大小与其他虚假缺陷行的虚假缺陷不同。
    • 10. 发明授权
    • Silver halide photographic light-sensitive material
    • 卤化银照相感光材料
    • US5013637A
    • 1991-05-07
    • US596776
    • 1990-10-11
    • Kazuya Tsukada
    • Kazuya Tsukada
    • G03C1/30G03C1/76G03C1/85G03C1/89
    • G03C1/85G03C1/89
    • A silver halide photographic light-sensitive material is disclosed which is improved in antistatic property. The photographic material comprises a support, a silver halide emulsion layer and an antistatic layer comprising a water-soluble conductive polymer, a hydrophobic polymer particle and a silane coupling agent represented by the following Formula I: ##STR1## wherein X is an oxygen atom or a --OCO-- group; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each an alkyl group or an aryl group which may be the same or different and are allowed to be substituted, and at least one of the groups represented by R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is a group containing a double bond, a halogen atom, an epoxy group, an acid anhydride residue, an alkoxy group, an alkoxycarbonyl group, an amino group, an acryloyl group, a methacryloyl group, an acrylamido group, a methacrylamido group or a haloacylamino group; n.sup.1, n.sup.2 and n.sup.3 are each 0 or 1, which may be the same or different, provided that the total of n.sup.1, n.sup.2 and n.sup.3 is 1 or more.
    • 公开了一种抗静电性能得到改善的卤化银照相感光材料。 照相材料包括载体,卤化银乳剂层和包含水溶性导电聚合物,疏水性聚合物颗粒和由下式I表示的硅烷偶联剂的抗静电层:其中X为 氧原子或-OCO-基; R 1,R 2,R 3和R 4各自为可以相同或不同且被取代的烷基或芳基,R1,R2,R3和R4表示的基团中的至少一个为含有 双键,卤素原子,环氧基,酸酐残基,烷氧基,烷氧基羰基,氨基,丙烯酰基,甲基丙烯酰基,丙烯酰胺基,甲基丙烯酰胺基或卤代酰氨基; n1,n2和n3各自为0或1,其可以相同或不同,条件是n1,n2和n3的总数为1或更大。