专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20140308685A1 ANTIBODY CAPABLE OF BINDING TO SPECIFIC REGION OF PERIOSTIN, AND METHOD FOR MEASURING PERIOSTIN USING SAME 有权
标题翻译：能够结合周期蛋白的特定区域的抗体以及使用其测量周期蛋白的方法
公开(公告)号：US20140308685A1
公开(公告)日：2014-10-16
申请号：US14342996
申请日：2012-09-06
申请人： Kenji Izuhara , Shoichiro Ohta , Kazuhiko Arima , Hiroshi Shiraishi , Shoichi Suzuki , Tomoaki Hoshino , Yoshinori Azuma , Junya Ono
发明人： Kenji Izuhara , Shoichiro Ohta , Kazuhiko Arima , Hiroshi Shiraishi , Shoichi Suzuki , Tomoaki Hoshino , Yoshinori Azuma , Junya Ono
IPC分类号： G01N33/68 , C07K16/18
CPC分类号： G01N33/6893 , C07K16/18 , C07K2317/14 , C07K2317/33 , G01N2333/47 , G01N2800/12
摘要： The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin. The method of testing for pulmonary fibrosis or interstitial pneumonia of the present invention includes the steps of a) measuring the amount or concentration of periostin in a sample derived from a subject, which measuring includes detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin and b) comparing the amount or concentration of the periostin in the sample derived from the subject with an amount or concentration of periostin in a sample derived from a living body not suffering from pulmonary fibrosis and interstitial pneumonia.
摘要翻译：本发明提供了一种精度更高的用于测定样品中的骨膜素的方法和试剂，提高骨膜素测定精度的方法以及以更高的精度测定肺纤维化或间质性肺炎的方法。本发明的抗体与选自由EMI区域，R1区域，R2区域和骨膜素的R3区域或其切割产物组成的组中的至少一个区域结合。用于测定骨膜素的方法和试剂以及本发明的骨膜素测定精度的提高方法的特征在于，检测从由EMI区域，R1区域，R2区域和R3组成的组中选择的至少一个区域骨膜素的区域本发明的肺纤维化或间质性肺炎的检测方法包括以下步骤：a）测量衍生自受试者的样品中骨膜素的量或浓度，所述测量包括检测至少一个选自以下的区域： EMI区域，R1区域，R2区域和骨膜素的R3区域，以及b）将源自受试者的样品中骨膜素的量或浓度与衍生自活体的样品中骨膜素的量或浓度进行比较不患肺纤维化和间质性肺炎。

2. 发明授权

US09347954B2 Antibody capable of binding to specific region of periostin, and method of measuring periostin using the same 有权
标题翻译：能够结合骨膜素的特定区域的抗体以及使用其的骨膜素测定方法
公开(公告)号：US09347954B2
公开(公告)日：2016-05-24
申请号：US14342996
申请日：2012-09-06
申请人： Kenji Izuhara , Shoichiro Ohta , Kazuhiko Arima , Hiroshi Shiraishi , Shoichi Suzuki , Tomoaki Hoshino , Yoshinori Azuma , Junya Ono
发明人： Kenji Izuhara , Shoichiro Ohta , Kazuhiko Arima , Hiroshi Shiraishi , Shoichi Suzuki , Tomoaki Hoshino , Yoshinori Azuma , Junya Ono
IPC分类号： C07K16/18 , G01N33/68
CPC分类号： G01N33/6893 , C07K16/18 , C07K2317/14 , C07K2317/33 , G01N2333/47 , G01N2800/12
摘要： The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin. The method of testing for pulmonary fibrosis or interstitial pneumonia of the present invention includes the steps of a) measuring the amount or concentration of periostin in a sample derived from a subject, which measuring includes detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin and b) comparing the amount or concentration of the periostin in the sample derived from the subject with an amount or concentration of periostin in a sample derived from a living body not suffering from pulmonary fibrosis and interstitial pneumonia.
摘要翻译：本发明提供了一种精度更高的用于测定样品中的骨膜素的方法和试剂，提高骨膜素测定精度的方法以及以更高的精度测定肺纤维化或间质性肺炎的方法。本发明的抗体与选自由EMI区域，R1区域，R2区域和骨膜素的R3区域或其切割产物组成的组中的至少一个区域结合。用于测定骨膜素的方法和试剂以及本发明的骨膜素测定精度的提高方法的特征在于，检测从由EMI区域，R1区域，R2区域和R3组成的组中选择的至少一个区域骨膜素的区域本发明的肺纤维化或间质性肺炎的检测方法包括以下步骤：a）测量衍生自受试者的样品中骨膜素的量或浓度，所述测量包括检测至少一个选自以下的区域： EMI区域，R1区域，R2区域和骨膜素的R3区域，以及b）将源自受试者的样品中骨膜素的量或浓度与衍生自活体的样品中骨膜素的量或浓度进行比较不患肺纤维化和间质性肺炎。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式