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    • 1. 发明申请
    • ANTIBODY CAPABLE OF BINDING TO SPECIFIC REGION OF PERIOSTIN, AND METHOD FOR MEASURING PERIOSTIN USING SAME
    • 能够结合周期蛋白的特定区域的抗体以及使用其测量周期蛋白的方法
    • US20140308685A1
    • 2014-10-16
    • US14342996
    • 2012-09-06
    • Kenji IzuharaShoichiro OhtaKazuhiko ArimaHiroshi ShiraishiShoichi SuzukiTomoaki HoshinoYoshinori AzumaJunya Ono
    • Kenji IzuharaShoichiro OhtaKazuhiko ArimaHiroshi ShiraishiShoichi SuzukiTomoaki HoshinoYoshinori AzumaJunya Ono
    • G01N33/68C07K16/18
    • G01N33/6893C07K16/18C07K2317/14C07K2317/33G01N2333/47G01N2800/12
    • The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin. The method of testing for pulmonary fibrosis or interstitial pneumonia of the present invention includes the steps of a) measuring the amount or concentration of periostin in a sample derived from a subject, which measuring includes detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin and b) comparing the amount or concentration of the periostin in the sample derived from the subject with an amount or concentration of periostin in a sample derived from a living body not suffering from pulmonary fibrosis and interstitial pneumonia.
    • 本发明提供了一种精度更高的用于测定样品中的骨膜素的方法和试剂,提高骨膜素测定精度的方法以及以更高的精度测定肺纤维化或间质性肺炎的方法。 本发明的抗体与选自由EMI区域,R1区域,R2区域和骨膜素的R3区域或其切割产物组成的组中的至少一个区域结合。 用于测定骨膜素的方法和试剂以及本发明的骨膜素测定精度的提高方法的特征在于,检测从由EMI区域,R1区域,R2区域和R3组成的组中选择的至少一个区域 骨膜素的区域 本发明的肺纤维化或间质性肺炎的检测方法包括以下步骤:a)测量衍生自受试者的样品中骨膜素的量或浓度,所述测量包括检测至少一个选自以下的区域: EMI区域,R1区域,R2区域和骨膜素的R3区域,以及b)将源自受试者的样品中骨膜素的量或浓度与衍生自活体的样品中骨膜素的量或浓度进行比较 不患肺纤维化和间质性肺炎。
    • 3. 发明授权
    • Electrically-operated two-wheeled vehicle
    • 电动两轮车
    • US08534408B2
    • 2013-09-17
    • US13614428
    • 2012-09-13
    • Eisuke KajiharaDai KataokaJun AdachiJunya OnoAsuka Ito
    • Eisuke KajiharaDai KataokaJun AdachiJunya OnoAsuka Ito
    • B62D61/02B62M6/00
    • B62M7/12B60Y2200/126B62K2204/00Y10T74/19Y10T74/19126
    • An electrically-operated two wheeled vehicle provided with a swing unit which pivotally supports a drive wheel WR. The swing unit includes: a first rotary electric machine having a first rotor; a second rotary electric machine having a second rotor; and a planetary gear mechanism which combines a rotational drive force of the first and second rotors to each other and transmits a product of rotational drive forces to a drive wheel WR in a state where a rotational speed is increased. The first and second rotary electric machines are arranged parallel to each other in the longitudinal direction of a vehicle such that an axis Ax2 of the second rotor is positioned in front of an axis Ax1 of the first rotor along the vehicle body. This arrangement prevents a height position of a lower surface of a swing unit from becoming excessively low.
    • 一种电动二轮车,其具有枢转地支撑驱动轮WR的摆动单元。 摆动单元包括:具有第一转子的第一旋转电机; 具有第二转子的第二旋转电机; 以及行星齿轮机构,其将第一和第二转子的旋转驱动力彼此组合,并且在旋转速度增加的状态下将旋转驱动力的乘积传递到驱动轮WR。 第一和第二旋转电机在车辆的纵向彼此平行配置,使得第二转子的轴线Ax2位于沿着车体的第一转子的轴线Ax1的前方。 这种布置防止摆动单元的下表面的高度位置变得过低。
    • 5. 发明申请
    • SEAT BELT RETRACTOR
    • 座椅皮带扣
    • US20100193622A1
    • 2010-08-05
    • US12669280
    • 2008-07-14
    • Junya Ono
    • Junya Ono
    • B60R22/40
    • B60R22/40B60R2022/402
    • A seatbelt retractor includes an acceleration sensor. The acceleration sensor includes a sensor case having a supporting surface which is maintained horizontal. A self-standing inertia body whose bottom surface is placed on the supporting surface is installed inside the sensor case in a self-standing condition, and which tilts when a horizontal acceleration is exerted. An actuating member which, in accordance with a tilting movement of the self-standing inertia body, activates a lock mechanism to lock the extraction of the seat belt. An outer contour of a contact area where the supporting surface of the sensor case and the bottom surface of the self-standing inertia body are in surface contact is configured such that a distance from a center axis of the self-standing inertia body to the outer contour differ, in a horizontal plane, in a first direction and in a second direction orthogonal to the first direction.
    • 安全带卷收器包括加速度传感器。 加速度传感器包括具有保持水平的支撑表面的传感器壳体。 将底面放置在支撑面上的自立式惯性体安装在传感器外壳的自立状态下,当施加水平加速度时倾斜。 致动构件,其根据所述自立式惯性体的倾斜运动,启动锁定机构以锁定所述安全带的抽出。 传感器外壳的支撑面与自立式惯性体的底面接触的接触区域的外轮廓构成为从自支撑惯性体的中心轴到外侧的距离 轮廓在水平面上在与第一方向正交的第一方向和第二方向上不同。
    • 8. 发明申请
    • ELECTRICALLY-OPERATED TWO-WHEELED VEHICLE
    • 电动两轮车
    • US20130081893A1
    • 2013-04-04
    • US13614428
    • 2012-09-13
    • Eisuke KAJIHARADai KataokaJun AdachiJunya OnoAsuka Ito
    • Eisuke KAJIHARADai KataokaJun AdachiJunya OnoAsuka Ito
    • B62K11/00B62M11/14
    • B62M7/12B60Y2200/126B62K2204/00Y10T74/19Y10T74/19126
    • An electrically-operated two wheeled vehicle provided with a swing unit which pivotally supports a drive wheel WR. The swing unit includes: a first rotary electric machine having a first rotor; a second rotary electric machine having a second rotor; and a planetary gear mechanism which combines a rotational drive force of the first and second rotors to each other and transmits a product of rotational drive forces to a drive wheel WR in a state where a rotational speed is increased. The first and second rotary electric machines are arranged parallel to each other in the longitudinal direction of a vehicle such that an axis Ax2 of the second rotor is positioned in front of an axis Ax1 of the first rotor along the vehicle body. This arrangement prevents a height position of a lower surface of a swing unit from becoming excessively low.
    • 一种电动二轮车,其具有枢转地支撑驱动轮WR的摆动单元。 摆动单元包括:具有第一转子的第一旋转电机; 具有第二转子的第二旋转电机; 以及行星齿轮机构,其将第一和第二转子的旋转驱动力彼此组合,并且在旋转速度增加的状态下将旋转驱动力的乘积传递到驱动轮WR。 第一和第二旋转电机在车辆的纵向彼此平行配置,使得第二转子的轴线Ax2位于沿着车体的第一转子的轴线Ax1的前方。 这种布置防止摆动单元的下表面的高度位置变得过低。