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    • 2. 发明授权
    • Implantable sensor and system for measurement and control of blood
constituent levels
    • 用于测量和控制血液成分水平的植入式传感器和系统
    • US6122536A
    • 2000-09-19
    • US981860
    • 1998-06-23
    • Xiaoguong SunJeffrey I. JosephKatherine D. Crothall
    • Xiaoguong SunJeffrey I. JosephKatherine D. Crothall
    • A61B5/145A61B5/00A61B5/029A61B5/1459A61B5/1495A61M5/142A61M5/172
    • A61M5/14276A61B5/0031A61B5/14532A61B5/1459A61B5/412A61B5/6876A61B5/6884A61B5/029A61M2205/3507A61M5/1723
    • This invention is an implantable sensor and system capable of measuring, controlling, monitoring and reporting blood constituent levels. The implantable sensor for sensing in vivo the level of at least one blood constituent in mammalian vascular tissue having at least one source of radiation from infrared through visible light, arranged to direct the radiation at the tissue where it is affected by interaction with the tissue, and at least one detector. The invention also encompasses a device for measuring and controlling the level of a blood constituent, such as glucose or oxygen, and includes an implantable infrared source module for generating an output signal representative of the sensed infrared radiation. The system includes a processor module responsive to the output signal which performs spectral analysis of the output signal and generates a control signal. The system further includes other devices for dispensing doses of medications or controlling organ function in response to the control signal.
    • PCT No.PCT / US96 / 11435 Sec。 371日期1998年6月23日第 102(e)1998年6月23日PCT PCT 1996年7月8日PCT公布。 出版物WO97 / 01986 日期1997年1月23日本发明是能够测量,控制,监测和报告血液成分水平的植入式传感器和系统。 用于在体内感测哺乳动物血管组织中至少一种血液成分的水平的植入式传感器,其具有至少一个来自红外线的可见光的辐射源,所述至少一个源通过可见光被引导,以将辐射引导到组织受到与组织的相互作用的影响, 和至少一个检测器。 本发明还包括用于测量和控制诸如葡萄糖或氧的血液成分的水平的装置,并且包括用于产生表示所感测的红外辐射的输出信号的可植入红外源模块。 该系统包括响应于输出信号的处理器模块,其执行输出信号的频谱分析并产生控制信号。 该系统还包括用于分配药物剂量或响应于控制信号控制器官功能的其它装置。
    • 5. 发明授权
    • System and method for managing diabetes
    • 治疗糖尿病的系统和方法
    • US07179226B2
    • 2007-02-20
    • US10176390
    • 2002-06-19
    • Katherine D. CrothallBogdan Butoi-TeodorescuPeter Laakmann
    • Katherine D. CrothallBogdan Butoi-TeodorescuPeter Laakmann
    • A61B5/00
    • G06F19/3475G06F19/00G06F19/3456G16H10/60G16H40/63Y10S128/92
    • A diabetes management system and method used to manage the blood glucose level of a diabetes patient. The system includes at least one portable electronic device and a database system. The portable electronic device allows the patient to input different types of data into the processor to calculate insulin and carbohydrate intake recommendations for the patient. A time/date stamp is individually generated and stored for each type of data inputted by the patient. The diabetes management system also includes a database system which stores (i) activity data associated with the physical activity of the patient, (ii) blood glucose data associated with the blood glucose level of the patient, (iii) meal intake data associated with the food intake of the patient, and (iv) insulin intake data associated with the insulin intake of the patient.
    • 用于管理糖尿病患者血糖水平的糖尿病管理系统和方法。 该系统包括至少一个便携式电子设备和数据库系统。 便携式电子设备允许患者将不同类型的数据输入到处理器中以计算患者的胰岛素和碳水化合物摄入建议。 针对由患者输入的每种类型的数据分别生成和存储时间/日期戳。 糖尿病管理系统还包括数据库系统,其存储(i)与患者的身体活动相关的活动数据,(ii)与患者的血糖水平相关联的血糖数据,(iii)与 患者的食物摄取量,和(iv)与患者的胰岛素摄入量相关的胰岛素摄入量数据。