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1. 发明申请

US20110224279A1 ANTICANCER AGENT 审中-公开
标题翻译： ANTICANCER代理
公开(公告)号：US20110224279A1
公开(公告)日：2011-09-15
申请号：US12920167
申请日：2009-02-27
申请人： Waldemar Kolanus , Michael Karl Hoch , Joachim L. Schultze , Birgit Loeer
发明人： Waldemar Kolanus , Michael Karl Hoch , Joachim L. Schultze , Birgit Loeer
IPC分类号： A61K31/713 , C07H21/02 , C07K7/08 , C12N15/12 , C07K16/00 , C07K9/00 , C12Q1/00 , C12Q1/68 , A61P35/00
CPC分类号： A61K38/1709 , A61K38/10 , C07K14/47
摘要： The present invention relates to a nucleic acid molecule and a pharmaceutical or diagnostic composition for the therapeutic and/or prophylactic treatment or diagnosis of cancer and/or metastasis thereof, comprising a nucleic acid molecule, or an amino acid sequence related to Trim71 and/or its mammalian and non mammalian orthologs and/or a nucleic acid sequence of the gene encoding for Trim71 and/or its mammalian and non mammalian orthologs.
摘要翻译：本发明涉及用于治疗和/或预防治疗或诊断其癌症和/或转移的核酸分子和药物或诊断组合物，其包含核酸分子或与Trim71相关的氨基酸序列和/或其哺乳动物和非哺乳动物直系同源物和/或编码Trim71和/或其哺乳动物和非哺乳动物直系同源物的基因的核酸序列。

2. 发明授权

US5429025A Severing apparatus for sheet-laminating machines 失效
标题翻译：片材层压机切割装置
公开(公告)号：US5429025A
公开(公告)日：1995-07-04
申请号：US143422
申请日：1993-10-26
申请人： Peter Bartsch , Karl Hoch
发明人： Peter Bartsch , Karl Hoch
IPC分类号： B26D1/29 , B26D5/02 , B26D7/01 , B32B38/00
CPC分类号： B32B38/0004 , B26D1/295 , B26D5/02 , B26D7/015 , B32B37/223 , Y10T83/02 , Y10T83/4812 , Y10T83/734 , Y10T83/741 , Y10T83/9401
摘要： A severing apparatus for sheet-laminating machines for separating sheets, transported as single sheets and coated with a continuous film layer, with severing of the overhanging film layer in the edge region of the overlapping area by means of a moving knife, wherein on a rotary table taking hold of the sheet line from below, at least one and preferably several knives, distributed at equal intervals over the periphery, are pivotably mounted with an essentially radial cutting edge, which, by means of a cam control, on passing over the edge of the sheet line, can be lowered from a raised position into an operating position gliding on the sheet line and can be raised again running up from the sheet line, and wherein the circumferential speed of the knife section cutting into the film layer is appreciably greater than the conveying speed of the sheet line.
摘要翻译：一种用于分离作为单片并被涂覆有连续薄膜层的薄片层压机的切断装置，其中借助于移动的刀将重叠区域的边缘区域中的悬垂薄膜层切断，其中在旋转从下方抓住片材线的工作台，在周边上以相等的间隔分布的至少一个并且优选多个刀片的工作台可枢转地安装有基本上径向的切割边缘，该基本上径向的切割边缘通过凸轮控制在通过边缘可以从升起位置降低到在片材线上滑动的工作位置，并且可以从片材线再次升高，并且切割成膜层的刀具部分的圆周速度明显更大比片材线的输送速度快。

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