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1. 发明申请

US20190091237A1 METHOD FOR PREVENTION OR TREATMENT OF DIABETIC COMPLICATIONS 审中-公开
公开(公告)号：US20190091237A1
公开(公告)日：2019-03-28
申请号：US15864665
申请日：2018-01-08
申请人： KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人： Kwon-Soo HA , Yeon-Ju LEE , Min-Soo KIM
IPC分类号： A61K31/5517 , A61P3/10
CPC分类号： A61K31/5517 , A61P3/10
摘要： Disclosed is a composition for the prevention or treatment of diabetic complications, containing a benzodiazepine-based compound, thereby effectively preventing or treating diseases resulting from hyperglycemia, which is the leading cause of diabetes, especially diseases caused by vascular leakage.

2. 发明申请

US20180145341A1 COMPONENT FOR FUEL CELL INCLUDING GRAPHENE FOAM AND FUNCTIONING AS FLOW FIELD AND GAS DIFFUSION LAYER 审中-公开
公开(公告)号：US20180145341A1
公开(公告)日：2018-05-24
申请号：US15814839
申请日：2017-11-16
申请人： Seoul National University, R&DB Foundation , Institute for Basic Science , Kangwon National University, University-Industry Cooperation Foundation
发明人： Yung-Eun SUNG , Yong-Hun CHO , Ji Eun PARK , Chi-Yeong AHN , Sungjun KIM
IPC分类号： H01M8/0234 , H01M8/0258 , H01M8/1018 , H01M8/241 , H01M8/04007
CPC分类号： H01M8/0234 , H01M8/0258 , H01M8/04007 , H01M8/1004 , H01M8/1018 , H01M8/241 , H01M2008/1095
摘要： The present invention relates to a component including graphene foam and functioning as a flow field and a gas diffusion layer (GDL) for a fuel cell. More particularly, a component functioning as a flow field and a GDL for a fuel cell according to the present invention is made of graphene foam that enhances mass transport and suffers no corrosion under operating conditions of the fuel cell when compared with a conventional flow field, thereby realizing excellent performance and durability. Furthermore, the component functions as the GDL so a thickness of a membrane electrode assembly is reduced thereby improving cell performance significantly.

3. 发明申请

US20170175167A1 COMPOSITION FOR DIAGNOSING CANCER USING PKA ACTIVITY AND INFORMATION PROVIDING METHOD FOR DIAGNOSING METASTASIS 审中-公开
公开(公告)号：US20170175167A1
公开(公告)日：2017-06-22
申请号：US15123840
申请日：2014-05-13
申请人： AMOGREENTECH CO., LTD. , KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人： Kwon-Soo HA , Deok-Hoon KONG
IPC分类号： C12Q1/48 , C12N9/12
CPC分类号： C12Q1/485 , C12N9/1205 , G01N33/574 , G01N2333/912
摘要： Disclosed is a composition for diagnosing cancer, including an agent for measuring PKA (Protein Kinase A) activity.

4. 发明申请

US20170084965A1 MANUFACTURING METHOD OF HIGH PURITY LITHIUM PHOSPHATE FROM THE WASTE LIQUID OF THE EXHAUSTED LITIUM-ION BATTERY 审中-公开
公开(公告)号：US20170084965A1
公开(公告)日：2017-03-23
申请号：US15240792
申请日：2016-08-18
申请人： KANGWON NATIONAL UNIVERSITY University-Industry Cooperation Foundation
发明人： Young Jun SONG
IPC分类号： H01M10/54 , B01D15/10 , B04B1/00 , C22B3/24 , C02F1/66 , C01B25/30 , C22B26/12 , C22B3/46 , H01M10/0525 , C02F11/00
CPC分类号： H01M10/54 , B01D15/10 , C01B25/30 , C01B25/301 , C01B25/303 , C02F1/5236 , C02F11/14 , C02F2101/105 , C02F2103/34 , C22B7/006 , C22B26/12 , H01M4/5825 , H01M10/0525 , Y02P10/234 , Y02W30/84
摘要： Provided is a method of manufacturing a high-purity lithium phosphate by utilizing a lithium waste liquid of a wasted battery. Lithium phosphate is manufactured and refined by using a minimized amount of sodium hydroxide and by using phosphate, lithium hydroxide, and an optimized pH condition, so that it is possible to manufacture high-purity lithium phosphate from which fine impurities which cannot be removed by cleaning are effective removed. A waste water treatment process of processing waste water as to be immediately discharged is integrated, so that the method is very efficient and environment-friendly. Therefore, since the high-purity lithium phosphate can be manufactured by utilizing a lithium waste liquid discarded in a wasted battery recycling process, the method has an effect in that the method is applied to a wasted battery recycling industry to prevent environmental pollution and facilitate recycling resources.

5. 发明授权

US09390710B2 Method for reranking speech recognition results 有权
标题翻译：重新排列语音识别结果的方法
公开(公告)号：US09390710B2
公开(公告)日：2016-07-12
申请号：US14604991
申请日：2015-01-26
申请人： SOGANG UNIVERSITY RESEARCH FOUNDATION , KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人： Jung Yun Seo , Sang Woo Kang , Myoung-Wan Koo , Hark Soo Kim , Hyeok Ju Ahn , Yeong Kil Song , Maeng Sik Choi
IPC分类号： G10L15/06
CPC分类号： G10L15/063 , G10L15/08 , G10L25/27 , G10L2015/0635
摘要： Provided is a speech recognition method using machine learning, including: receiving a speech signal as an input, performing speech recognition to generate speech recognition result information including multiple candidate sentences and ranks of the respective candidate sentences; processing the multiple candidate sentences included in the speech recognition result information according to a machine learning model which is learned in advance and changing the ranks of the multiple candidate sentences to re-rank the multiple candidate sentences; and selecting the highest-rank candidate sentence among the re-ranked multiple candidate sentences as a speech recognition result. Particularly, the machine learning model is generated by: receiving the speech signal and a correct answer sentence as inputs; generating the speech recognition result information and a correct answer set; generating learning data by using the correct answer set; and performing the machine learning of changing the ranks of the candidate sentences.
摘要翻译：提供了一种使用机器学习的语音识别方法，包括：接收语音信号作为输入，执行语音识别以产生包括各候选语句的多个候选句子和等级的语音识别结果信息; 根据预先学习的机器学习模型来处理包括在语音识别结果信息中的多个候选句子，并且改变多个候选句子的等级以重新排列多个候选句子; 并且在重新排列的多个候选句子中选择最高等级的候选句子作为语音识别结果。特别地，机器学习模型通过以下方式产生：接收语音信号和正确答案作为输入; 生成语音识别结果信息和正确答案集; 通过使用正确的答案集生成学习数据; 并执行机器学习改变候选句子的行列。

6. 发明申请

US20140128323A1 Method for prevention or treatment of diabetic angiogenesis impairment using C-peptide 有权
标题翻译：使用C肽预防或治疗糖尿病血管生成障碍的方法
公开(公告)号：US20140128323A1
公开(公告)日：2014-05-08
申请号：US13987544
申请日：2013-08-06
申请人： AMOGREENTECH CO., LTD. , KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人： Kwon-Soo Ha , Young-Cheol Lim
IPC分类号： A61K38/17
CPC分类号： A61K38/1709 , A61K38/17 , A61K38/1703
摘要： Disclosed are a method and a composition for the prevention or treatment of diabetic angiogenesis impairment or diabetic wound-healing impairment, using C-peptide. Found to be able to induce angiogenesis through chemotatic migration of endothelial cells, cell migration to wounded areas, capillary-like network formation, and ERK1/2 and Akt phosphorylation and NO production, C-peptide has prophylactic or therapeutic applications in a broad spectrum of various diabetic complications including diabetic angiogenesis impairment.
摘要翻译：公开了使用C肽预防或治疗糖尿病血管生成障碍或糖尿病性伤口愈合损伤的方法和组合物。发现能够通过内皮细胞的趋化性迁移，细胞迁移到受伤区域，毛细管样网络形成和ERK1 / 2和Akt磷酸化和NO产生来诱导血管发生，C-肽在广泛范围内具有预防或治疗应用各种糖尿病并发症包括糖尿病血管生成障碍。

7. 发明授权

US11492654B2 Method for measuring protein kinase activity and kit for same 有权
公开(公告)号：US11492654B2
公开(公告)日：2022-11-08
申请号：US15123859
申请日：2014-05-13
申请人： AMOGREENTECH CO., LTD. , KANGWON NATIONAL UNIVERSITY UNIVERSITY—INDUSTRY COOPERATION FOUNDATION
发明人： Kwon-Soo Ha , Deok-Hoon Kong
IPC分类号： C12Q1/48
摘要： Disclosed is a method of measuring protein kinase activity, including a) attaching GMBS (N-[γ-maleimidobutyryloxy]sulfosuccinimide ester) to a base plate, b) attaching a substrate that reacts with a protein kinase to the base plate having GMBS attached thereto, thus manufacturing a kit for measuring protein kinase activity, c) introducing, to the kit, a mixture of a sample to be analyzed and a buffer including triton X-100, and d) probing phosphorylation of the substrate caused by the protein kinase contained in the sample, thereby measuring the activity of the protein kinase.

8. 发明授权

US11020405B2 Method for prevention or treatment of diabetic complications 有权
公开(公告)号：US11020405B2
公开(公告)日：2021-06-01
申请号：US16428073
申请日：2019-05-31
申请人： KANGWON NATIONAL UNIVERSITY UNIVERSITY-INDUSTRY COOPERATION FOUNDATION
发明人： Kwon-Soo Ha , Yeon-Ju Lee , Min-Soo Kim
IPC分类号： A61K31/197 , A61K31/5517 , A61P3/10
摘要： Disclosed is a composition for the prevention or treatment of diabetic complications, containing a benzodiazepine-based compound, thereby effectively preventing or treating diseases resulting from hyperglycemia, which is the leading cause of diabetes, especially diseases caused by vascular leakage.

9. 发明授权

US10897890B2 Microchip mimicking female reproductive organs and method for fabricating the same 有权
公开(公告)号：US10897890B2
公开(公告)日：2021-01-26
申请号：US16014138
申请日：2018-06-21
申请人： KANGWON NATIONAL UNIVERSITY University-Industry Cooperation Foundation
发明人： Seung Tae Lee , Jung Im Yun , Song Baek
IPC分类号： A01N1/02 , C12N5/071 , C12M3/06 , G01N1/30 , C12M1/22 , C12N5/075 , A61D19/02 , C12N5/076 , C12M1/32
摘要： A microchip includes a first chamber and second chamber formed to a predetermined depth in a member made of polydimethylsiloxane (PDMS); and a channel (microchannel) connecting the first chamber to the second chamber. These components mimic in vivo organs which produce by selecting capacitated motile sperm from semen and causing the selected sperm to meet mature oocyte, and these components are capable of effectively producing motile capacitated good-quality sperms from sperms ejaculated outside the body.

10. 发明申请

US20190256479A1 METHOD OF PREPARING EZETIMIBE AND INTERMEDIATE THEREOF 审中-公开
公开(公告)号：US20190256479A1
公开(公告)日：2019-08-22
申请号：US16146129
申请日：2018-09-28
申请人： Kangwon National University, University Industry Cooperation Foundation
发明人： Phil Ho Lee , Koo Yeon Lee , Yonghyeon Baek , Kyusik Um , Byeong Su Kim
IPC分类号： C07D263/26 , C07D205/08 , B01J31/22 , B01J31/38
摘要： Disclosed is a method of preparing ezetimibe, including cross-metathesis using a Grubbs 2nd catalyst and deprotection using a Pearlman's catalyst, and an intermediate thereof. The method of preparing ezetimibe is useful as an efficient ezetimibe synthesis technique in pharmaceutical fields using ezetimibe as a raw material.

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