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1. 发明授权

US08554487B2 Method and apparatus for analyzing genotype data 有权
标题翻译：分析基因型数据的方法和装置
公开(公告)号：US08554487B2
公开(公告)日：2013-10-08
申请号：US11326164
申请日：2006-01-04
申请人： Ki-eun Kim , Kyung-Hee Park , Jung-joo Hwang , Jae-Heup Kim , Yeon-Su Lee , Kyusang Lee
发明人： Ki-eun Kim , Kyung-Hee Park , Jung-joo Hwang , Jae-Heup Kim , Yeon-Su Lee , Kyusang Lee
IPC分类号： G01N33/50
CPC分类号： G06F19/18 , G06F19/26
摘要： Provided are a method and apparatus for analyzing genotype data plotted in a two-dimensional space. The method includes: connecting points representing the genotype data to a predetermined point to form straight lines and obtaining angles between adjacent straight lines; extracting the two largest angles from the obtained angles; and analyzing the plotted genotype data using three groups of the genotype data separated by the two extracted largest angles. According to the present invention, when the experimental results of classifying genotype are to be analyzed, the two largest angles from the angles obtained by connecting straight lines between points representing each of the genotype data and a predetermined point plotted in a two-dimensional space are detected, and three data regions separated by the detected two largest angles are used to analyze the genotype data. Thus, a large amount of the experimental data for classifying the genotype can be analyzed rapidly and conveniently.
摘要翻译：提供了用于分析绘制在二维空间中的基因型数据的方法和装置。该方法包括：将表示基因型数据的点连接到预定点以形成直线并获得相邻直线之间的角度; 从所获得的角度提取两个最大角度; 并使用由两个提取的最大角度分离的三组基因型数据分析绘制的基因型数据。根据本发明，当分析基因型分类的实验结果时，通过连接表示各基因型数据的点和在二维空间中绘制的预定点之间的直线连接获得的角度的两个最大角度为检测到的三个数据区域被检测到的两个最大角度分开，以分析基因型数据。因此，可以快速方便地分析大量用于分类基因型的实验数据。

2. 发明申请

US20090139866A1 DEVICE FOR SEPARATING MICRO PARTICLES AND A METHOD FOR FABRICATING THE DEVICE 有权
标题翻译：用于分离微粒子的装置和用于制造装置的方法
公开(公告)号：US20090139866A1
公开(公告)日：2009-06-04
申请号：US12098870
申请日：2008-04-07
申请人： Yun Woo NAM , Jung Joo HWANG , Hyo-Il JUNG , Hui-Sung MOON , Jae Chan PARK , Jun Il SOHN , Kyoung Ho KANG
发明人： Yun Woo NAM , Jung Joo HWANG , Hyo-Il JUNG , Hui-Sung MOON , Jae Chan PARK , Jun Il SOHN , Kyoung Ho KANG
IPC分类号： B01D57/02 , C25B9/00 , B05D5/12
CPC分类号： B01D57/02 , B01L3/502761 , B01L3/502776 , B01L2200/0652 , B01L2300/0816 , B01L2400/0415 , B01L2400/0424 , B03C5/005 , B03C5/026
摘要： A device for separating micro particles is provided. The separating device comprises a sample inlet into which a sample containing micro particles is injected; fluid inlets into which fluid is injected to form a flow sheath for the sample; a plurality of outlets through which the micro particles are separated and discharged out; a channel through which the sample and the fluid flow; and a first electrode and a second electrode longitudinally disposed in parallel in the channel. The first and the second electrodes are provided in such a manner that an electrode gap between the first and the second electrodes has a curved shape. The micro particles in the sample are easily separated using a dielectrophoresis characteristic.
摘要翻译：提供了用于分离微粒的装置。分离装置包括样品入口，其中注入包含微粒的样品; 注入流体的流体入口形成样品的流动鞘; 多个出口，微粒分离出来并排出; 样品和流体流过的通道; 以及在所述通道中纵向并列设置的第一电极和第二电极。第一和第二电极被设置成使得第一和第二电极之间的电极间隙具有弯曲的形状。使用介电电泳特性容易地分离样品中的微粒。

3. 发明申请

US20090045063A1 APPARATUS AND METHOD FOR DETECTING PARTICLES AND MICROORGANISMS USING MAGNETIC FIELD 审中-公开
标题翻译：使用磁场检测颗粒和微生物的装置和方法
公开(公告)号：US20090045063A1
公开(公告)日：2009-02-19
申请号：US12048625
申请日：2008-03-14
申请人： Kyoung Ho KANG , Jung Joo HWANG , Jaechan PARK , Yunwoo NAM , Junil SOHN
发明人： Kyoung Ho KANG , Jung Joo HWANG , Jaechan PARK , Yunwoo NAM , Junil SOHN
IPC分类号： G01N27/26 , G01N27/30
CPC分类号： G01N15/0656
摘要： Disclosed are an apparatus and a method for detecting particles and microorganisms using a magnetic field. The apparatus comprises a magnetic sensor that is provided at an outside of a passage pipe and measures a magnetic field induced by fluid moving in the passage pipe; an electrode that is provided in the passage pipe so as to apply electric current having a predetermined frequency to the fluid moving in the passage pipe to measure impedance; and a signal processing unit that uses an intensity of the magnetic field measured by the magnetic sensor and the impedance measured by the electrode to determine concentrations of particles and microorganisms included in the fluid. According to an embodiment of the invention, using electrical properties of the particles or microorganisms, it is possible to quantitatively analyze and to identify the particles or microorganisms in real time, to improve a measuring accuracy and to manufacture an ultra small-scaled particle and microorganism detecting apparatus having a simple structure.
摘要翻译：公开了使用磁场检测颗粒和微生物的装置和方法。该装置包括设置在通道管的外侧的磁传感器，并测量在通道管中流体移动引起的磁场; 电极，其设置在所述通道管内，以便对在所述通道管中移动的流体施加具有预定频率的电流以测量阻抗; 以及信号处理单元，其使用由磁传感器测量的磁场的强度和由电极测量的阻抗来确定流体中包括的颗粒和微生物的浓度。根据本发明的一个实施方案，使用颗粒或微生物的电特性，可以实时定量分析和鉴定颗粒或微生物，以提高测量精度并制造超小型颗粒和微生物检测装置具有简单的结构。

4. 发明授权

US07375210B2 PCR primer set for detecting severe acute respiratory syndrome (SARS)-Coronavirus, method and kit for detecting SARS-Coronavirus using the same 有权
标题翻译：用于检测严重急性呼吸综合征（SARS）的PCR引物组 - 用于检测SARS的冠状病毒的冠状病毒，方法和试剂盒
公开(公告)号：US07375210B2
公开(公告)日：2008-05-20
申请号：US10997462
申请日：2004-11-24
申请人： Hee-kyun Lim , Sang-hyo Kim , Jung-joo Hwang , Young-sun Lee , Young-a Kim
发明人： Hee-kyun Lim , Sang-hyo Kim , Jung-joo Hwang , Young-sun Lee , Young-a Kim
IPC分类号： C07H21/04
CPC分类号： C12Q1/701
摘要： Provided are SARS-CoV detection PCR primers having nucleotide sequences as set forth in SEQ ID NOS: 1-46, a method for detecting SARS-CoV using the primers, and a SARS-CoV detection kit including the primers.
摘要翻译：提供具有SEQ ID NO：1-46所示核苷酸序列的SARS-CoV检测PCR引物，使用引物检测SARS-CoV的方法和包含引物的SARS-CoV检测试剂盒。

5. 发明申请

US20050186602A1 Method for amplifying a nucleic acid using a solid phase material coated with a carboxyl group or amino group 审中-公开
标题翻译：使用涂覆有羧基或氨基的固相材料来扩增核酸的方法
公开(公告)号：US20050186602A1
公开(公告)日：2005-08-25
申请号：US11042376
申请日：2005-01-25
申请人： Joon-ho Kim , Yoon-kyoung Cho , Jung-joo Hwang , Geun-bae Lim , Jeong-gun Lee
发明人： Joon-ho Kim , Yoon-kyoung Cho , Jung-joo Hwang , Geun-bae Lim , Jeong-gun Lee
IPC分类号： C12N15/10 , C12P19/34 , C12Q1/68
CPC分类号： C12N15/1006
摘要： A method for amplifying a nucleic acid using a solid phase material coated with a carboxyl group or an amino group is provided. The method includes contacting a mixture of a nucleic acid containing sample and a salt solution with the solid phase material coated with a carboxyl group or an amino group to form a nucleic acid-solid phase material complex, washing the nucleic acid-solid phase material complex with a wash buffer, and adding a reaction solution for amplifying a nucleic acid to the nucleic acid-solid phase material complex to perform an amplification reaction.
摘要翻译：提供了使用涂覆有羧基或氨基的固相材料来扩增核酸的方法。该方法包括将含有核酸的样品和盐溶液的混合物与涂覆有羧基或氨基的固相材料接触以形成核 - 固相物质络合物，洗涤核酸 - 固相物质络合物用洗涤缓冲液加入用于将核酸扩增至核酸 - 固相物质络合物的反应溶液进行扩增反应。

6. 发明申请

US20050182571A1 Sequence indexing method and system 审中-公开
标题翻译：序列索引方法和系统
公开(公告)号：US20050182571A1
公开(公告)日：2005-08-18
申请号：US11056774
申请日：2005-02-11
申请人： Ki-eun Kim , Jung-joo Hwang
发明人： Ki-eun Kim , Jung-joo Hwang
IPC分类号： G06F17/30 , G06F19/00 , G06F19/22 , G06F19/28 , G06F17/60 , G01V3/00 , G01V7/00
CPC分类号： G06F16/90344 , G06F2216/11 , G16B30/00
摘要： A sequence indexing method includes: parsing a patent document having a sequence number and a sequence list on the basis of a typical expression of a country to which the patent document was registered; first extracting the sequence number and the sequence list from the parsed patent document; and second extracting a sequence, which corresponds to the extracted sequence number, from the extracted sequence list.
摘要翻译：序列索引方法包括：根据专利文献注册的国家的典型表达方式对具有序列号和序列表的专利文献进行解析; 首先从解析的专利文献中提取序列号和序列表; 并且从提取的序列列表中第二次提取对应于所提取的序列号的序列。

7. 发明申请

US20050037414A1 PCR primer set for detecting hepatitis B virus, method for detecting hepatitis B using the primer set, and hepatitis B virus detection kit including the primer set 有权
标题翻译：用于检测乙型肝炎病毒的PCR引物组，使用引物组检测乙型肝炎的方法，以及包括引物组的乙型肝炎病毒检测试剂盒
公开(公告)号：US20050037414A1
公开(公告)日：2005-02-17
申请号：US10918000
申请日：2004-08-13
申请人： Young-sun Lee , Jung-im Han , Jung-joo Hwang , Mi-kyung Kim , Yoon-kyoung Cho , Hee-kyun Lim , Young-a Kim
发明人： Young-sun Lee , Jung-im Han , Jung-joo Hwang , Mi-kyung Kim , Yoon-kyoung Cho , Hee-kyun Lim , Young-a Kim
IPC分类号： C12N15/09 , C12Q1/68 , C12Q1/70 , C12P19/34
CPC分类号： C12Q1/706 , C12Q2565/629 , C12Q2565/543 , C12Q2531/113
摘要： Provided are a primer set selected from the group consisting of primers having nucleotide sequences as set forth in SEQ ID NOS: 1-40, a method for detecting hepatitis B virus by polymerase chain reaction (PCR) using the primer set, and a hepatitis B virus detection kit including the primer set.
摘要翻译：提供了选自由SEQ ID NO：1-40所示的核苷酸序列的引物组成的引物组，使用引物组的聚合酶链反应（PCR）检测乙型肝炎病毒的方法，以及乙型肝炎病毒检测试剂盒包括引物组。

8. 发明授权

US07517650B2 Method of diagnosing breast cancer and compositions therefor 有权
标题翻译：诊断乳腺癌的方法及其组成
公开(公告)号：US07517650B2
公开(公告)日：2009-04-14
申请号：US11368141
申请日：2006-03-03
申请人： Yun-sun Nam , Seung-Hak Choi , Jae-Heup Kim , Jung-joo Hwang , Yeon-Su Lee , Tae-jin Ahn
发明人： Yun-sun Nam , Seung-Hak Choi , Jae-Heup Kim , Jung-joo Hwang , Yeon-Su Lee , Tae-jin Ahn
IPC分类号： C07H21/04 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/156
摘要： A method of diagnosing breast cancer in an individual aged younger than 41 or older than 54 is provided. The method comprises obtaining a nucleic acid from the individual and determining a nucleotide at a polymorphic site of the nucleic acid. Polynucleotides specific to breast cancer, a microarray comprising the polynucleotides, and diagnostic kits are also provided.
摘要翻译：提供了一种在年龄小于41岁或以下的个体中诊断乳腺癌的方法。该方法包括从个体获得核酸并确定核酸的多态位点处的核苷酸。还提供了对乳腺癌特异性的多核苷酸，包含多核苷酸的微阵列和诊断试剂盒。

9. 发明申请

US20080194422A1 PCR PRIMER SET DETECTING SEVERE ACUTE RESPIRATORY SYNDROME (SARS)-CORONAVIRUS, METHOD AND KIT FOR DETECTING SARS-CORONAVIRUS USING THE SAME 审中-公开
标题翻译： PCR PRIMER SET检测严重的急性呼吸综合征（SARS） - 用于检测使用其的SARS-CORONAVIRUS的方法和试剂盒
公开(公告)号：US20080194422A1
公开(公告)日：2008-08-14
申请号：US12106686
申请日：2008-04-21
申请人： Hee-kyun LIM , Sang-hyo KIM , Jung-joo HWANG , Young-sun LEE , Young-a KIM
发明人： Hee-kyun LIM , Sang-hyo KIM , Jung-joo HWANG , Young-sun LEE , Young-a KIM
IPC分类号： C40B30/10 , C07H21/00 , C12Q1/68
CPC分类号： C12Q1/701
摘要： Provided are SARS-CoV detection PCR primers having nucleotide sequences as set forth in SEQ ID NOS: 1-46, a method for detecting SARS-CoV using the primers, and a SARS-CoV detection kit including the primers.
摘要翻译：提供具有SEQ ID NO：1-46所示核苷酸序列的SARS-CoV检测PCR引物，使用引物检测SARS-CoV的方法和包含引物的SARS-CoV检测试剂盒。

10. 发明申请

US20080096186A1 PCR PRIMER SET FOR DETECTING SEVERE ACUTE RESPIRATORY SYNDROME (SARS)-CORONAVIRUS, METHOD AND KIT FOR DETECTING SARS-CORONAVIRUS USING THE SAME 有权
标题翻译：用于检测严重急性呼吸道综合征（SARS）的PCR引物组 - 用于检测使用其的SARS-角膜结肠炎的方法和试剂盒
公开(公告)号：US20080096186A1
公开(公告)日：2008-04-24
申请号：US10997462
申请日：2004-11-24
申请人： Hee-kyun Lim , Sang-hyo Kim , Jung-joo Hwang , Young-sun Lee , Young-a Kim
发明人： Hee-kyun Lim , Sang-hyo Kim , Jung-joo Hwang , Young-sun Lee , Young-a Kim
IPC分类号： C12Q1/70 , C12Q1/68 , C07H21/02
CPC分类号： C12Q1/701
摘要： Provided are SARS-CoV detection PCR primers having nucleotide sequences as set forth in SEQ ID NOS: 1-46, a method for detecting SARS-CoV using the primers, and a SARS-CoV detection kit including the primers.
摘要翻译：提供具有SEQ ID NO：1-46所示核苷酸序列的SARS-CoV检测PCR引物，使用引物检测SARS-CoV的方法和包含引物的SARS-CoV检测试剂盒。

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