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1. 发明授权

US5307693A Force-sensing system, including a magnetically mounted rocking element 失效
标题翻译：力传感系统，包括一个磁力安装的摇摆元件
公开(公告)号：US5307693A
公开(公告)日：1994-05-03
申请号：US7304
申请日：1993-01-21
申请人： Joseph E. Griffith , Gabriel L. Miller
发明人： Joseph E. Griffith , Gabriel L. Miller
IPC分类号： G01L1/14 , G01B7/34 , G01L1/08 , G01L1/16 , G01N37/00 , G01Q60/38
CPC分类号： G01Q60/38 , B82Y35/00 , Y10S977/865 , Y10S977/873
摘要： A force-sensing system suitable, for example, for atomic force microscopy. This system includes a rocking beam, a base, and means for supporting the beam adjacent a surface of the base such that the beam can pivot about at least one axis parallel to the base surface. In contrast to rocking-beam systems of the prior art, the support means comprise at least one pivot element that can be held against the base surface by a magnetic field.
摘要翻译：适用于例如原子力显微镜的力感测系统。该系统包括摆动梁，基座和用于支撑邻近基座的表面的梁的装置，使得梁可绕平行于基座表面的至少一个轴线枢转。与现有技术的摇臂系统相比，支撑装置包括至少一个枢转元件，该枢轴元件可通过磁场抵靠基座表面。

2. 发明授权

US5756887A Mechanism for changing a probe balance beam in a scanning probe microscope 失效
标题翻译：在扫描探针显微镜中更换探头平衡梁的机制
公开(公告)号：US5756887A
公开(公告)日：1998-05-26
申请号：US807310
申请日：1997-02-27
申请人： Charles E. Bryson, III , Joseph E. Griffith , Gabriel L. Miller
发明人： Charles E. Bryson, III , Joseph E. Griffith , Gabriel L. Miller
IPC分类号： G01B11/24 , G01B21/30
CPC分类号： G01Q70/02 , B82Y35/00 , Y10S977/86
摘要： A scanning probe microscope equipped with a mechanism for exchanging a probe balance beam from the scan head, wherein the probe balance beam is of the type which is magnetically constrained on the scan head. A magnet having a magnetic field strength greater than that of the scan head magnet is utilized to overcome the attractive force exerted on the balance beam by the scan head magnet and transfer the balance beam from the scan head to a plate in a holding station on the sample table of the microscope. Completely automatic operation is achieved without operator handling of the balance beam.
摘要翻译：一种配备有用于从扫描头交换探针平衡光束的机构的扫描探针显微镜，其中探针平衡光束是被磁力约束在扫描头上的类型。利用具有大于扫描磁头磁体的磁场强度的磁体来克服由扫描磁头磁体施加在平衡梁上的吸引力，并将平衡梁从扫描头传送到保持站上的板上样品台的显微镜。无需操作人员处理平衡梁即可实现全自动操作。

3. 发明授权

US5627371A Tilting positioner for a micropositioning device 失效
标题翻译：用于微型定位装置的倾斜定位器
公开(公告)号：US5627371A
公开(公告)日：1997-05-06
申请号：US600658
申请日：1996-02-09
申请人： Joseph E. Griffith , Rafael N. Kleiman
发明人： Joseph E. Griffith , Rafael N. Kleiman
IPC分类号： G01N37/00 , G01B7/34 , G01N23/00 , G01N27/00 , G01Q10/04 , G02B7/00 , G05D3/00 , G05D3/10 , H02N2/00
CPC分类号： G01Q10/04 , B82Y35/00 , Y10S977/872
摘要： A scanning probe microscope positioner including an elongated rigid member which is controllably tilted in a predictable manner. One end of the rigid member is subjected to differential motion on opposite sides of its longitudinal axis so as to cause its opposite end to partake of lateral displacement which is a magnification of the differential motion. By a careful selection of component materials and sizes, inherent thermal compensation can be attained.
摘要翻译：扫描探针显微镜定位器，其包括可预测地可控地倾斜的细长的刚性构件。刚性构件的一端在其纵向轴线的相对侧上受到差动运动，从而使其相对端部偏移作为差速运动的放大倍率。通过仔细选择部件材料和尺寸，可以获得固有的热补偿。

4. 发明授权

US5032574A Novel antimicrobial peptide 失效
标题翻译：新型抗菌肽
公开(公告)号：US5032574A
公开(公告)日：1991-07-16
申请号：US199206
申请日：1988-05-26
申请人： Craig G. Wilde , Joseph E. Griffith , Marian N. Marra , Randal W. Scott
发明人： Craig G. Wilde , Joseph E. Griffith , Marian N. Marra , Randal W. Scott
IPC分类号： C12N15/09 , A61K38/00 , A61P31/04 , C07K1/14 , C07K1/18 , C07K1/20 , C07K14/47 , C12N5/10 , C12P21/02 , C12R1/91
CPC分类号： C07K14/4723 , A61K38/00
摘要： This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu- leu-arg-val-gly-asn-cys-leu-ile-gly-gly-val-ser-phe-thr-try-cys-thr-arg-val. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.
摘要翻译：本发明提供了可用作抗微生物剂的纯化多肽。该纯化的多肽已经衍生自人粒细胞，分子量约为3,700道尔顿，N-末端氨基酸序列为val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr -glu-leu-arg-val-gly-asn-cys-leu-ile-gly-gly-val-ser-phe-thr-try-cys-thr-ar-val-val。本发明还提供了生产该多肽的方法，含该多肽的药物组合物及其用途。

5. 发明授权

US4501060A Dielectrically isolated semiconductor devices 失效
标题翻译：绝缘半导体器件
公开(公告)号：US4501060A
公开(公告)日：1985-02-26
申请号：US460399
申请日：1983-01-24
申请人： Robert C. Frye , Joseph E. Griffith , Yiu H. Wong
发明人： Robert C. Frye , Joseph E. Griffith , Yiu H. Wong
IPC分类号： H01L21/20 , H01L21/762 , H01L21/306 , H01L21/76
CPC分类号： H01L21/76264 , H01L21/2007 , H01L21/76297 , H01L21/76275 , H01L21/76283 , Y10S438/977
摘要： Dielectrically isolated single crystal silicon of high quality is produced by an extremely convenient process. This process involves the fusing of two silicon bodies where at least one of these bodies has a region of silicon oxide. The bodies are contacted so that the silicon oxide is at an interface between the two bodies. The bodies are then heated to an elevated temperature while applying a nominal electrical potential across the interface. This combination of applied potential and temperature permanently fuses the two bodies without producing any significant damage to the crystal quality of these bodies.
摘要翻译：通过非常方便的工艺生产高质量的绝缘隔离单晶硅。该方法涉及两个硅体的熔合，其中这些主体中的至少一个具有氧化硅区域。物体接触，使得氧化硅在两个物体之间的界面处。然后将这些物体加热到升高的温度，同时在界面上施加标称电位。这种施加电位和温度的组合使两个物体永久熔化，而不会对这些物体的晶体质量造成任何显着的损害。

6. 发明授权

US5210027A DNA encoding novel antimicrobial polypeptide and methods for obtaining such polypeptide 失效
标题翻译：编码新型抗微生物多肽的DNA和获得这种多肽的方法
公开(公告)号：US5210027A
公开(公告)日：1993-05-11
申请号：US730341
申请日：1991-07-15
申请人： Craig G. Wilde , Joseph E. Griffith , Marian N. Marra , Randal W. Scott
发明人： Craig G. Wilde , Joseph E. Griffith , Marian N. Marra , Randal W. Scott
IPC分类号： A61K38/00 , C07K14/47 , C12N1/21 , C12N15/12
CPC分类号： C07K14/4723 , A61K38/00
摘要： This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu-leu-arg-val-gly-asn-cys-leu-ilu-gly-gly-val-ser-phe-thr-tyr-cys-cys-thr-arg-val. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.
摘要翻译：本发明提供了可用作抗微生物剂的纯化多肽。该纯化的多肽已经衍生自人粒细胞，分子量约为3,700道尔顿，N-末端氨基酸序列为val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr -glu-leu-arg-val-gly-作为n-cys-leu-ilu-gly-gly-val-ser-phe-thr-tyr-cys-cys-thr-arg-val。本发明还提供了生产该多肽的方法，含该多肽的药物组合物及其用途。

7. 发明授权

US5693997A Non-tilting plate actuator for use in a micropositioning device 失效
标题翻译：用于微型定位装置的非倾斜板致动器
公开(公告)号：US5693997A
公开(公告)日：1997-12-02
申请号：US599570
申请日：1996-02-09
申请人： Joseph E. Griffith , Rafael N. Kleiman
发明人： Joseph E. Griffith , Rafael N. Kleiman
IPC分类号： G01B7/34 , G01N13/00 , G01N27/00 , G01Q10/04 , H01J37/20 , H01L41/09 , H02N2/02 , H02N2/00 , H01L41/08
CPC分类号： G01Q10/04 , B82Y35/00 , H01L41/0953 , H01L41/096 , H02N2/028
摘要： A non-tilting positioner for a micropositioning device constructed of piezoelectric plate actuators each arranged with a pair of opposed parallel edges respectively coupled to first and second elements. A first surface of each plate is divided into quadrants, with first electrodes in each of the quadrants. At least one second electrode is provided on the opposed surface. Electric voltages are applied to the first and second electrodes with appropriate polarities so as to generate an electric field through the thickness of the plate which is of a first polarity in a first pair of diagonally opposite quadrants and is of the opposite polarity in the second pair of diagonally opposite quadrants. Movement along a line parallel to the plane of the plate is thereby effected. Movement in a third orthogonal direction can also be attained by selecting an appropriate electrode pattern. A compact design with double the range is attained by providing at least two of the aforedescribed actuators which are arranged with their plates in parallel or coplanar relation to each other, with a rigid intermediate element being coupled to one end of each of the actuator plates. This "doubling back" of the plates is inherently thermally compensated and eliminates parasitic vertical motion associated with the desired horizontal motion.
摘要翻译：一种用于由压电板致动器构成的微定位装置的非倾斜定位器，每个压电板致动器均布置有分别联接到第一和第二元件的一对相对的平行边缘。每个板的第一表面被分成象限，每个象限中具有第一电极。在相对表面上设置至少一个第二电极。以适当的极性将电压施加到第一和第二电极，以便通过在第一对斜面相对象限中具有第一极性的板的厚度产生电场，并且在第二对中具有相反极性的电场的对角相对的象限。从而平行于板的平面的线移动。也可以通过选择合适的电极图案来实现第三正交方向的移动。通过提供至少两个上述致动器来实现具有两倍范围的紧凑设计，所述至少两个致动器以它们的板彼此平行或共面的关系布置，刚性中间元件联接到每个致动器板的一端。板的“加倍”是固有的热补偿，并消除与期望的水平运动相关联的寄生垂直运动。

8. 发明授权

US4457972A Enhanced adhesion by high energy bombardment 失效
标题翻译：通过高能量轰击增强附着力
公开(公告)号：US4457972A
公开(公告)日：1984-07-03
申请号：US327896
申请日：1981-12-07
申请人： Joseph E. Griffith , Yuanxun Qiu , Thomas A. Tombrello
发明人： Joseph E. Griffith , Yuanxun Qiu , Thomas A. Tombrello
IPC分类号： B29C35/08 , B29C65/14 , C23C26/02 , H01L21/263 , H01L21/3105 , H01L21/48 , H01L31/0224 , H01L31/0392 , H05K1/03 , H05K3/04 , H05K3/38 , B32B7/04 , B32B15/04
CPC分类号： B29C65/1425 , B29C65/1403 , B29C65/1496 , B29C66/45 , B29C66/472 , B32B37/06 , C23C26/02 , H01L21/263 , H01L21/3105 , H01L21/4846 , H01L31/0224 , H05K3/381 , B29C2035/0872 , B29C66/71 , B29C66/7392 , B29C66/7394 , B32B2310/0881 , B32B2311/02 , B32B2311/12 , H05K1/0306 , H05K1/032 , H05K2201/015 , H05K2203/0528 , H05K2203/107 , H05K3/04 , H05K3/388 , Y02E10/50 , Y10S228/903 , Y10S428/901 , Y10T428/24917 , Y10T428/263 , Y10T428/264 , Y10T428/265 , Y10T428/31536 , Y10T428/31544 , Y10T428/31678 , Y10T428/31692 , Y10T428/31699
摘要： Films (12) of gold, copper, silicon nitride, or other materials are firmly bonded to insulator substrates (12) such as silica, a ferrite, or Teflon (polytetrafluorethylene) by irradiating the interface with high energy ions. Apparently, track forming processes in the electronic stopping region cause intermixing in a thin surface layer resulting in improved adhesion without excessive doping. Thick layers can be bonded by depositing or doping the interfacial surfaces with fissionable elements or alpha emitters.
摘要翻译：金，铜，氮化硅或其他材料的薄膜（12）通过用高能离子照射界面而牢固地结合到绝缘体基底（12）如二氧化硅，铁氧体或特氟隆（聚四氟乙烯）上。显然，电子停止区域中的轨迹形成过程导致在薄的表面层中混合，导致改善的粘合性而不会过度掺杂。可以通过用可裂变元件或α发射体沉积或掺杂界面来结合厚层。

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