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1. 发明申请

US20070255162A1 Bioimpedance measurement system and method 有权
标题翻译：生物阻抗测量系统和方法
公开(公告)号：US20070255162A1
公开(公告)日：2007-11-01
申请号：US11283057
申请日：2005-11-18
申请人： Marwan Abboud , Johnny Asmar , Chadi Harmouche
发明人： Marwan Abboud , Johnny Asmar , Chadi Harmouche
IPC分类号： A61B5/05
CPC分类号： A61B5/0537 , A61B18/02 , A61B2017/00026 , A61B2018/0022 , A61B2018/0212
摘要： Methods and systems for detecting fluid egress, assessing lesion quality, determining tissue composition or structure, determining ice coverage of catheter tip and providing tissue contact assessment, by providing a catheter having a shaft with a proximal end portion and a distal end portion, the proximal end portion and the distal end portion define at least one fluid pathway therebetween with the shaft having a plurality of electrodes, positioning the catheter at a tissue treatment site, applying an electrical current between at least two of the plurality of electrodes, measuring impedance voltage between the at least two of the plurality of electrodes and, processing the measured impedance voltage caused by the applied electrical current to determine if fluid egress is present, to assess lesion quality, to determine tissue composition, ice cover of catheter tip, and to provide contact assessment. The system may have a control unit, a microprocessor, an impedance measuring device or the like to perform processing of impedance data.
摘要翻译：用于检测流体出口的方法和系统，评估病变质量，确定组织组成或结构，通过提供具有近端部分和远端部分的轴的导管，确定导管尖端的冰覆盖和提供组织接触评估，末端部分和远端部分限定其间的至少一个流体通路，其中轴具有多个电极，将导管定位在组织治疗部位，在多个电极中的至少两个之间施加电流，测量多个电极之间的阻抗电压所述多个电极中的至少两个，并且处理由施加的电流引起的测量的阻抗电压以确定是否存在流体出口，以评估病变质量，确定组织组成，导管尖端的冰盖，并提供接触评定。系统可以具有控制单元，微处理器，阻抗测量装置等，以执行阻抗数据的处理。

2. 发明申请

US20060259023A1 Contact assessment of balloon catheters 有权
标题翻译：球囊导管接触评估
公开(公告)号：US20060259023A1
公开(公告)日：2006-11-16
申请号：US11129205
申请日：2005-05-13
申请人： Marwan Abboud , Teresa Mihalik , Johnny Asmar , Chadi Harmouche
发明人： Marwan Abboud , Teresa Mihalik , Johnny Asmar , Chadi Harmouche
IPC分类号： A61B18/02
CPC分类号： A61B5/6885 , A61B5/053 , A61B5/0538 , A61B5/6886 , A61B18/02 , A61B2017/00026 , A61B2017/00039 , A61B2017/00084 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2090/065
摘要： A method and system for determining contact assessment includes the steps of positioning a catheter at a tissue treatment site, where the catheter has a proximal end portion and a distal end portion, the proximal end portion defining at least one fluid inlet port and at least one fluid outlet port, an expandable membrane defining a cooling chamber a coolant injection lumen in fluid communication with the at least one fluid inlet port and the cooling chamber, a coolant return lumen in fluid communication with the at least one fluid outlet port and the cooling chamber, the coolant injection tube, the cooling chamber, and the primary coolant return lumen defining a fluid pathway and a temperature sensor located near the coolant return lumen; measuring an internal temperature of the chamber, and modifying the position of the catheter in response to the measured temperature. The method and system can also use a measured impedance to determine contact assessment.
摘要翻译：用于确定接触评估的方法和系统包括将导管定位在组织治疗部位的步骤，其中所述导管具有近端部分和远端部分，所述近端部分限定至少一个流体入口端口和至少一个流体出口端口，限定冷却室的可膨胀膜，与所述至少一个流体入口和所述冷却室流体连通的冷却剂注入腔，与所述至少一个流体出口和所述冷却室流体连通的冷却剂返回内腔冷却剂注入管，冷却室和第一冷却剂回流腔限定流体通路和位于冷却剂回流腔附近的温度传感器; 测量腔室的内部温度，以及响应于测量的温度改变导管的位置。该方法和系统还可以使用测量的阻抗来确定接触评估。

3. 发明申请

US20060030843A1 Endovascular cryotreatment catheter 有权
公开(公告)号：US20060030843A1
公开(公告)日：2006-02-09
申请号：US11244710
申请日：2005-10-06
申请人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Luckge , Jean-Luc Pageard , Marwan Abboud , Johnny Asmar , Abderrahim Benrabah , Ken Chen , John Lehmann , Philippe Marchand , Robert Martin , Fredric Milder , Daniel Nahon
发明人： Miriam Lane , Leonilda Capuano , David Holtan , Jean-Pierre Lalonde , Claudia Luckge , Jean-Luc Pageard , Marwan Abboud , Johnny Asmar , Abderrahim Benrabah , Ken Chen , John Lehmann , Philippe Marchand , Robert Martin , Fredric Milder , Daniel Nahon
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22001 , A61B2017/22051 , A61B2017/22054 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter. Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. Various configurations, such as surface modification of the balloon interface, or placement of particles, coatings, or expandable meshes or coils in the balloon interface, may be employed to achieve this function.

4. 发明申请

US20050228367A1 Leak detection system for catheter based medical device 审中-公开
标题翻译：基于导管的医疗器械泄漏检测系统
公开(公告)号：US20050228367A1
公开(公告)日：2005-10-13
申请号：US11129021
申请日：2005-05-13
申请人： Marwan Abboud , Johnny Asmar , John Lehmann
发明人： Marwan Abboud , Johnny Asmar , John Lehmann
IPC分类号： A61B18/02 , A61B18/18
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/0212 , A61B2018/0262
摘要： The present invention provides a medical device having an elongate body, which includes an injection lumen, an exhaust lumen, and a guidewire lumen. The medical device further includes a first pliable element defining a cooling chamber, and a second pliable element at least partially enclosing the first pliable element, defining a junction between the first and second pliable element. Moreover, a first leak detector is provided in fluid communication with the cooling chamber, while a second leak detector is in fluid communication with the junction. In addition, the medical device may be in communication with a control console, a fluid supply, or a vacuum source.
摘要翻译：本发明提供一种具有细长主体的医疗装置，其包括注射腔，排气腔和导丝腔。医疗装置还包括限定冷却室的第一柔韧元件和至少部分地包围第一柔韧元件的第二柔韧元件，其限定第一和第二柔韧元件之间的接合部。此外，第一泄漏检测器设置成与冷却室流体连通，而第二泄漏检测器与结点流体连通。此外，医疗装置可以与控制台，流体供应或真空源连通。

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