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1. 发明申请

US20090029877A1 Automated System for Isolating, Amplifying, and Detecting a Target Nucleic Acid Sequence Present in a Fluid Sample 审中-公开
标题翻译：用于分离，扩增和检测存在于流体样品中的靶核酸序列的自动系统
公开(公告)号：US20090029877A1
公开(公告)日：2009-01-29
申请号：US12241349
申请日：2008-09-30
申请人： Kelly G. AMMANN , Ralph E. BURNS , Ernest V. Hansberry , Glenn A. HORNER , Cheryl A. JAKUB , John E. KLING , Donald J. NIEGLOS , Robert E. Schneider , Robert J. SMITH
发明人： Kelly G. AMMANN , Ralph E. BURNS , Ernest V. Hansberry , Glenn A. HORNER , Cheryl A. JAKUB , John E. KLING , Donald J. NIEGLOS , Robert E. Schneider , Robert J. SMITH
IPC分类号： C40B60/12 , C12M1/40
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译：用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，进行分析物分离程序，以及确定目标分析物的存在的站。自动插座输送系统将反应容器从一个站移动到另一个站。分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

2. 发明申请

US20080268528A1 Automated analyzer for use in performing nucleic Acid-based amplification reactions 有权
标题翻译：用于进行基于核酸的扩增反应的自动分析仪
公开(公告)号：US20080268528A1
公开(公告)日：2008-10-30
申请号：US11873818
申请日：2007-10-17
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12M1/34 , C12M1/40
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译：用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。分析仪包括用于自动准备标本样品的台站，在规定温度下培养样品规定的时间，进行分析物分离程序，并确定目标分析物的存在。自动插座输送系统将反应容器从一个站移动到另一个站。分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

3. 发明授权

US06335166B1 Automated process for isolating and amplifying a target nucleic acid sequence 有权
标题翻译：用于分离和扩增靶核酸序列的自动化过程
公开(公告)号：US06335166B1
公开(公告)日：2002-01-01
申请号：US09303030
申请日：1999-04-30
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12Q168
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译：用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，预处理分析物分离程序以及确定目标分析物的存在的站。自动插座输送系统将反应容器从一个站移动到另一个站。分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

4. 发明授权

US4348209A Determining quantitative degree of ethylene oxide exposure in sterilization processes 失效
标题翻译：确定灭菌过程中环氧乙烷暴露的定量程度
公开(公告)号：US4348209A
公开(公告)日：1982-09-07
申请号：US305418
申请日：1981-09-25
申请人： J. Barry Murtaugh , Dean G. Laurin , John E. Kling , Archie G. Woodworth
发明人： J. Barry Murtaugh , Dean G. Laurin , John E. Kling , Archie G. Woodworth
IPC分类号： G01N33/00 , G01N31/04 , G01N31/10
CPC分类号： G01N33/0047
摘要： A method of quantitatively determining the amount of exposure of an object to ethylene oxide gas. A preweighed ethylene oxide-permeable container, which encloses a predetermined amount of catalyst for the reaction of the ethylene oxide gas to form a liquid, is placed adjacent to the object. The object and container are then exposed to ethylene oxide gas for controlled time and at a known humidity and temperature. The container is then reweighed. The weight gain of the container is a quantitative indication of the amount of exposure to ethylene oxide gas. The test system may be calibrated against its effect in known concentrations of ethylene oxide gas, so that the precise amount of exposure to ethylene oxide gas can be determined.
摘要翻译：定量测定物体与环氧乙烷气体的接触量的方法。包围预定量的用于环氧乙烷气体反应形成液体的催化剂的预先称重的环氧乙烷渗透性容器被放置在与物体相邻的位置。然后将物体和容器暴露于环氧乙烷气体以控制时间并且在已知的湿度和温度下。然后将容器重新称重。容器的重量增加是暴露于环氧乙烷气体的量的定量指示。测试系统可以根据其在已知浓度的环氧乙烷气体中的影响进行校准，从而可以确定暴露于环氧乙烷气体的精确量。

5. 发明授权

US07560256B2 Automated process for detecting the presence of a target nucleic acid in a sample 有权
标题翻译：用于检测样品中靶核酸的存在的自动化过程
公开(公告)号：US07560256B2
公开(公告)日：2009-07-14
申请号：US11168374
申请日：2005-06-29
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12P19/34 , C12Q1/68 , C07H21/02 , C07H21/04 , C07H21/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated process for detecting the presence of a target nucleic acid in a sample. The process includes separating the target nucleic acid from other material present in the sample at a first station, transferring the separated target nucleic acid from the first station to a second station using a rotatable transport mechanism, combining the transferred target nucleic acid and reagents for performing an amplification reaction at the second station, and performing an amplification reaction. A product of the amplification reaction is detected as an indication of the presence of the target nucleic acid in the sample.
摘要翻译：用于检测样品中靶核酸的存在的自动化过程。该方法包括在第一站将目标核酸与样品中存在的其他物质分离，使用可转移的转运机制将分离的目标核酸从第一站转移到第二站，将转移的靶核酸和试剂结合，以进行第二站的扩增反应，进行扩增反应。检测扩增反应的产物作为样品中靶核酸的存在的指示。

6. 发明申请

US20090095419A1 Method and Apparatus for Stripping a Contact-Limiting Element from a Pipette Probe 有权
公开(公告)号：US20090095419A1
公开(公告)日：2009-04-16
申请号：US12335814
申请日：2008-12-16
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： B29C63/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

7. 发明授权

US5201725A Needle free I.V. adapter 失效
标题翻译：无针脚I.V. 适配器
公开(公告)号：US5201725A
公开(公告)日：1993-04-13
申请号：US765807
申请日：1991-09-26
申请人： John E. Kling
发明人： John E. Kling
IPC分类号： A61M39/00 , A61M39/02 , A61M39/26
CPC分类号： A61M39/02 , A61M39/26
摘要： A medical connector assembly comprises a connector body having a fluid passage there through, a valve member, and means, responsive to a compressive force placed on the medical connector, for permitting a fluid to freely communicate between openings in the connector body. The valve member can be constructed using a single element having a slit therein or it can be constructed using two separate halves which when joined together form an interface slit. In a preferred embodiment, when a compressive force is exerted against the connector body, sufficient distortion is experienced by the valve member to open the slit and permit fluid flow between connector body openings.
摘要翻译：医疗连接器组件包括连接器主体，其具有通过其的流体通道，阀构件和响应于放置在医疗连接器上的压缩力的装置，用于允许流体在连接器主体中的开口之间自由连通。阀构件可以使用在其中具有狭缝的单个元件来构造，或者可以使用两个分开的半部构造，当连接在一起形成界面狭缝时。在优选实施例中，当对连接器主体施加压缩力时，阀构件经受了充分的变形以打开狭缝并允许流体在连接器主体开口之间流动。

8. 发明授权

US09598723B2 Automated analyzer for performing a nucleic acid-based assay 有权
公开(公告)号：US09598723B2
公开(公告)日：2017-03-21
申请号：US11873818
申请日：2007-10-17
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12M1/34 , C12M1/40 , C12Q1/68 , B01F9/00 , B01L7/00 , B03C1/28 , B03C1/30 , G01N35/02 , B01L9/06 , G01N35/00 , G01N35/10 , G01N35/04
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

9. 发明授权

US08569020B2 Method for simultaneously performing multiple amplification reactions 有权
标题翻译：进行多重核酸扩增程序的方法
公开(公告)号：US08569020B2
公开(公告)日：2013-10-29
申请号：US12241350
申请日：2008-09-30
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12P1/34 , C12Q1/68 , C07H21/02 , C07H21/04 , C07H21/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated method for performing multiple nucleic acid amplification procedures in multiple receptacles of a set of receptacles contained in an analyzer.
摘要翻译：一种用于在包含在分析器中的一组容器的多个容器中执行多个核酸扩增程序的自动化方法。

10. 发明授权

US08569019B2 Method for performing an assay with a nucleic acid present in a specimen 有权
标题翻译：用存在于样品中的核酸进行测定的方法
公开(公告)号：US08569019B2
公开(公告)日：2013-10-29
申请号：US11931722
申请日：2007-10-31
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： C12P19/34 , C12Q1/68 , C07H21/02 , C07H21/04 , C07H21/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated process for isolating and amplifying a target nucleic acid in a self-contained analyzer.
摘要翻译：用于在自含分析仪中分离和扩增靶核酸的自动化方法。

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