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1. 发明申请

US20160271312A1 CATHETER CONNECTION SYSTEM FOR ULTRAVIOLET LIGHT DISINFECTION 审中-公开
标题翻译：用于超紫外线消毒的导管连接系统
公开(公告)号：US20160271312A1
公开(公告)日：2016-09-22
申请号：US15074854
申请日：2016-03-18
申请人： Justin A. LANCE , Stephen BOWER , John E. ASHLEY , Jeffrey ETTER , Julia A. RASOOLY , Michael RASOOLY , Benjamin S. ARNETT
发明人： Justin A. LANCE , Stephen BOWER , John E. ASHLEY , Jeffrey ETTER , Julia A. RASOOLY , Michael RASOOLY , Benjamin S. ARNETT
IPC分类号： A61M1/28 , A61L2/00 , A61M39/16
CPC分类号： A61M1/285 , A61L2/0047 , A61M39/16 , A61M2039/167
摘要： Systems and methods of disinfection of catheter connections are provided. A transfer catheter connector can include a UV-transparent window at its distal end and a sealing plunger proximal to the UV-transparent window. A solution set connector can be inserted inside a portion of the transfer catheter connector to connect a solution set and transfer catheter. The solution set connector comprises a lumen covered by a leading membrane surface; a sealing surface configured to sealingly engage the window surface, and a piercing member configured to pierce the membrane surface. The sealing plunger, membrane surface, and window define a disinfection zone. The connectors can be connected in a disinfection position configuration in which flow is not permitted between the catheters and the connectors are irradiated with UV light. After disinfection, the connectors are advanced to a flow position in which the piercing member pierces the membrane surface, enabling flow between the catheters.
摘要翻译：提供导管连接消毒的系统和方法。转移导管连接器可包括其远端处的UV透明窗口和靠近UV透明窗口的密封柱塞。解决方案组连接器可插入转移导管连接器的一部分内，以连接溶液组和转移导管。解决方案集连接器包括被前导膜表面覆盖的管腔; 被构造成密封地接合窗表面的密封表面和构造成刺穿膜表面的刺穿构件。密封柱塞，膜表面和窗口限定了消毒区。连接器可以连接在消毒位置配置中，其中导管之间不允许流动，并且用紫外线照射连接器。在消毒之后，连接器前进到穿刺部件穿透膜表面的流动位置，从而能够在导管之间流动。

2. 发明授权

US08998924B2 Insertion handle for surgical implants 有权
标题翻译：插入手柄用于外科植入物
公开(公告)号：US08998924B2
公开(公告)日：2015-04-07
申请号：US13264498
申请日：2010-04-15
申请人： Philip J. Simpson , George A. Mansfield , Damien J. Shulock , David G. Matsuura , Walter Dean Gillespie , John E. Ashley
发明人： Philip J. Simpson , George A. Mansfield , Damien J. Shulock , David G. Matsuura , Walter Dean Gillespie , John E. Ashley
IPC分类号： A61B17/58 , A61B17/60 , A61F2/00 , A61F2/46 , A61F2/30
CPC分类号： A61F2/4611 , A61F2002/30133 , A61F2002/30538 , A61F2002/4628 , A61F2230/0015 , A61F2250/0006
摘要： An insertion handle for medical implants includes a handle with an elongate shaft extending therefrom and connection means for the implant disposed at the end of the shaft opposite the handle. The connection means includes a pivotable attachment for the implant that is controlled remotely from the handle. Both angle of the implant with respect to the handle and shaft as well as the attachment may be separately controlled and adjusted. Remote angular adjustment facilitates insertion of implants in to small surgical sites because the orientation of the implant may be repeatedly, remotely adjusted as the implant is inserted. Connectors may also be provided at the engagement surface between the handle and implant in order to provide communication with the implant or surgical site. The connectors also may serve as torque bearing members to avoid the need for separate torque bearing means such as keyways and the like.
摘要翻译：用于医疗植入物的插入手柄包括具有从其延伸的细长轴的手柄和用于植入物的连接装置，其设置在与手柄相对的轴的端部处。连接装置包括用于植入物的可枢转附件，其从手柄远程地控制。植入物相对于手柄和轴的角度以及附件可以单独控制和调整。远程角度调节有利于将植入物插入小手术部位，因为植入物的插入方向可以重复地进行远程调整。也可以在手柄和植入物之间的接合表面处设置连接器，以便提供与植入物或手术部位的连通。连接器还可以用作扭矩轴承构件，以避免需要单独的扭矩承载装置，例如键槽等。

3. 发明授权

US08894710B2 Lockable spinal implant 有权
标题翻译：可锁定脊柱植入物
公开(公告)号：US08894710B2
公开(公告)日：2014-11-25
申请号：US13486679
申请日：2012-06-01
申请人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
发明人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
IPC分类号： A61F2/44 , A61F2/30 , A61F2/48
CPC分类号： A61F2/44 , A61F2/30742 , A61F2/442 , A61F2/4455 , A61F2002/30079 , A61F2002/3008 , A61F2002/30133 , A61F2002/30365 , A61F2002/30405 , A61F2002/30476 , A61F2002/30484 , A61F2002/30499 , A61F2002/30505 , A61F2002/30514 , A61F2002/30522 , A61F2002/30525 , A61F2002/3055 , A61F2002/30579 , A61F2002/30581 , A61F2002/30589 , A61F2002/30601 , A61F2002/30841 , A61F2002/482 , A61F2002/485 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2230/0015 , A61F2250/0007 , A61F2250/0069 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration.
摘要翻译：脊柱植入物，其构造成部署在相邻的椎体之间。植入物具有至少一个具有缩回构型的可延伸的支撑元件，以便于植入物的展开和延伸构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。角度畸形也可以被修正，自然曲率恢复。优选地，植入物在其未展开状态下具有小于其通常通过以在椎间空间内展开的神经孔的尺寸的最小尺寸。植入物设置有锁定系统，优选地具有多个锁定元件以将植入物锁定在延伸构造中。

4. 发明申请

US20120130387A1 Insertion Handle For Surgical Implants 有权
标题翻译：插入手术用于手术植入物
公开(公告)号：US20120130387A1
公开(公告)日：2012-05-24
申请号：US13264498
申请日：2010-04-15
申请人： Philip J. Simpson , George A. Mansfield , Damien J. Shulock , David G. Matsuura , Walter Dean Gillespie , John E. Ashley
发明人： Philip J. Simpson , George A. Mansfield , Damien J. Shulock , David G. Matsuura , Walter Dean Gillespie , John E. Ashley
IPC分类号： A61B17/56
CPC分类号： A61F2/4611 , A61F2002/30133 , A61F2002/30538 , A61F2002/4628 , A61F2230/0015 , A61F2250/0006
摘要： An insertion handle for medical implants includes a handle with an elongate shaft extending therefrom and connection means for the implant disposed at the end of the shaft opposite the handle. The connection means includes a pivotable attachment for the implant that is controlled remotely from the handle. Both angle of the implant with respect to the handle and shaft as well as the attachment may be separately controlled and adjusted. Remote angular adjustment facilitates insertion of implants in to small surgical sites because the orientation of the implant may be repeatedly, remotely adjusted as the implant is inserted. Connectors may also be provided at the engagement surface between the handle and implant in order to provide communication with the implant or surgical site. The connectors also may serve as torque bearing members to avoid the need for separate torque bearing means such as keyways and the like.
摘要翻译：用于医疗植入物的插入手柄包括具有从其延伸的细长轴的手柄和用于植入物的连接装置，其设置在与手柄相对的轴的端部处。连接装置包括用于植入物的可枢转附件，其从手柄远程地控制。植入物相对于手柄和轴的角度以及附件可以单独控制和调整。远程角度调节有利于将植入物插入小手术部位，因为植入物的插入方向可以重复地进行远程调整。也可以在手柄和植入物之间的接合表面处设置连接器，以便提供与植入物或手术部位的连通。连接器还可以用作扭矩轴承构件，以避免需要单独的扭矩承载装置，例如键槽等。

5. 发明申请

US20110190772A1 POWERED TISSUE MODIFICATION DEVICES AND METHODS 审中-公开
标题翻译：动力组织修改装置和方法
公开(公告)号：US20110190772A1
公开(公告)日：2011-08-04
申请号：US13078376
申请日：2011-04-01
申请人： Vahid Saadat , Jeffery L. Bleich , Kenneth J. Michlitsch , John E. Ashley
发明人： Vahid Saadat , Jeffery L. Bleich , Kenneth J. Michlitsch , John E. Ashley
IPC分类号： A61B17/56
CPC分类号： A61B17/1659 , A61B17/1671
摘要： A device for modifying tissue in a spine may include: a shah having a proximal portion and a distal portion, the distal portion having dimensions which allow h to be passed into an epidural space of the spine and between target and non-target tissues at least one distal force application member extending from the distal portion of the shall and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member.
摘要翻译：用于修改脊柱中的组织的装置可以包括：具有近端部分和远端部分的髋部，所述远端部分具有允许h至少进入脊柱的硬膜外腔和靶和非靶组织之间的尺寸从远端部分延伸的一个远端力施加构件应构造成便于将锚固力和张紧力中的至少一个施加到轴上; 至少一个可动组织修改构件，其在远端部分处或其附近与所述轴联接; 至少一个驱动构件与所述至少一个组织修改构件联接以激活所述至少一个组织修改构件; 以及与所述至少一个驱动构件联接的至少一个动力传递构件，以向所述至少一个驱动构件输送动力。

6. 发明申请

US20110130835A1 Adjustable Distraction Cage With Linked Locking Mechanisms 有权
标题翻译：可调牵引笼与链锁机构
公开(公告)号：US20110130835A1
公开(公告)日：2011-06-02
申请号：US12787281
申请日：2010-05-25
申请人： John E. Ashley , Philip J. Simpson , Walter Dean Gillespie , Damien J. Shulock , Murali Kadaba , David G. Matsuura , George A. Mansfield, III , Thomas Grotz , Rudy Pretti
发明人： John E. Ashley , Philip J. Simpson , Walter Dean Gillespie , Damien J. Shulock , Murali Kadaba , David G. Matsuura , George A. Mansfield, III , Thomas Grotz , Rudy Pretti
IPC分类号： A61F2/44
CPC分类号： A61F2/441 , A61F2/30742 , A61F2/442 , A61F2/4455 , A61F2/4611 , A61F2002/30079 , A61F2002/3008 , A61F2002/30133 , A61F2002/30365 , A61F2002/30405 , A61F2002/30476 , A61F2002/30484 , A61F2002/30499 , A61F2002/30505 , A61F2002/30514 , A61F2002/30522 , A61F2002/30525 , A61F2002/3055 , A61F2002/30551 , A61F2002/30565 , A61F2002/30579 , A61F2002/30581 , A61F2002/30589 , A61F2002/30601 , A61F2002/30841 , A61F2002/482 , A61F2002/485 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2230/0015 , A61F2250/0007 , A61F2250/0069 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a refracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning
摘要翻译：脊柱植入物，其构造成部署在相邻的椎体之间。植入物具有至少一个具有折射构造的可延伸的支撑元件，以便于植入物的展开和延伸的构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。植入物在其未展开状态下具有小于其通常通过的神经孔的尺寸的最小尺寸，以被部署在椎间空间内。植入物具有锁定系统，该锁定系统具有多个连接的锁定元件，其一致地工作以将植入物锁定在延伸构造中。也可以提供骨接合锚，以确保安全的定位

7. 发明申请

US20100145455A1 Lockable spinal implant 审中-公开
标题翻译：可锁定脊柱植入物
公开(公告)号：US20100145455A1
公开(公告)日：2010-06-10
申请号：US12380840
申请日：2009-03-04
申请人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
发明人： Philip J. Simpson , David G. Matsuura , Walter Dean Gillespie , George A. Mansfield, III , John E. Ashley
IPC分类号： A61F2/44
CPC分类号： A61F2/44 , A61F2/30742 , A61F2/442 , A61F2/4455 , A61F2002/30079 , A61F2002/3008 , A61F2002/30133 , A61F2002/30365 , A61F2002/30405 , A61F2002/30476 , A61F2002/30484 , A61F2002/30499 , A61F2002/30505 , A61F2002/30514 , A61F2002/30522 , A61F2002/30525 , A61F2002/3055 , A61F2002/30579 , A61F2002/30581 , A61F2002/30589 , A61F2002/30601 , A61F2002/30841 , A61F2002/482 , A61F2002/485 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2230/0015 , A61F2250/0007 , A61F2250/0069 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration.
摘要翻译：脊柱植入物，其构造成部署在相邻的椎体之间。植入物具有至少一个具有缩回构型的可延伸的支撑元件，以便于植入物的展开和延伸构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。角度畸形也可以被修正，自然曲率恢复。优选地，植入物在其未展开状态下具有小于其通常通过以在椎间空间内展开的神经孔的尺寸的最小尺寸。植入物设置有锁定系统，优选地具有多个锁定元件以将植入物锁定在延伸构造中。

8. 发明申请

US20100114318A1 Prosthetic Intervertebral Discs 审中-公开
标题翻译：假体椎间盘
公开(公告)号：US20100114318A1
公开(公告)日：2010-05-06
申请号：US11970156
申请日：2008-01-07
申请人： Darin C. Gittings , Michael L. Reo , Janine C. Robinson , John E. Ashley , Nicholas C. Koske , Roxanne L. Richman , Elizabeth V. Wistrom , Uriel Hiram Chee
发明人： Darin C. Gittings , Michael L. Reo , Janine C. Robinson , John E. Ashley , Nicholas C. Koske , Roxanne L. Richman , Elizabeth V. Wistrom , Uriel Hiram Chee
IPC分类号： A61F2/44 , A61B17/70
CPC分类号： A61F2/4425 , A61F2/30742 , A61F2/3094 , A61F2/442 , A61F2002/30009 , A61F2002/30014 , A61F2002/30075 , A61F2002/30133 , A61F2002/30168 , A61F2002/30179 , A61F2002/30224 , A61F2002/30331 , A61F2002/30387 , A61F2002/30462 , A61F2002/30471 , A61F2002/305 , A61F2002/30523 , A61F2002/3055 , A61F2002/30563 , A61F2002/30566 , A61F2002/30576 , A61F2002/30579 , A61F2002/30581 , A61F2002/30586 , A61F2002/30594 , A61F2002/30662 , A61F2002/30884 , A61F2002/30889 , A61F2002/30897 , A61F2002/30899 , A61F2002/30971 , A61F2002/4415 , A61F2002/443 , A61F2002/444 , A61F2002/448 , A61F2002/4495 , A61F2002/4677 , A61F2002/485 , A61F2210/0061 , A61F2220/0025 , A61F2220/0033 , A61F2220/0075 , A61F2220/0091 , A61F2230/0015 , A61F2230/0043 , A61F2230/0058 , A61F2230/0069 , A61F2250/0018 , A61F2250/0028
摘要： Prosthetic intervertebral discs, systems including such prosthetic intervertebral discs, and methods for using the same are described. The subject prosthetic discs include upper and lower endplates separated by a compressible core member. The subject prosthetic discs exhibit stiffness in the vertical direction, torsional stiffness, bending stiffness in the sagittal plane, and bending stiffness in the front plane, where the degree of these features can be controlled independently by adjusting the components, construction, and other features of the discs.
摘要翻译：描述了假体椎间盘，包括这种假体椎间盘的系统及其使用方法。主体假体盘包括由可压缩的芯构件分开的上端板和下端板。主体假体椎盘在垂直方向呈现刚度，扭转刚度，矢状面中的弯曲刚度和前平面中的弯曲刚度，其中这些特征的程度可以通过调整部件，构造和其他特征来独立地控制光盘。

9. 发明申请

US20100057204A1 Hydraulically Actuated Expanding Spine Cage With Extendable Locking Anchor 有权
标题翻译：液压驱动扩展脊柱笼与可扩展的锁定锚
公开(公告)号：US20100057204A1
公开(公告)日：2010-03-04
申请号：US12548260
申请日：2009-08-26
申请人： Murali Kadaba , Philip J. Simpson , John E. Ashley , Walter Dean Gillespie , Thomas Grotz , George A. Mansfield, III , David G. Matsuura , Rudy Peretti
发明人： Murali Kadaba , Philip J. Simpson , John E. Ashley , Walter Dean Gillespie , Thomas Grotz , George A. Mansfield, III , David G. Matsuura , Rudy Peretti
IPC分类号： A61F2/44
CPC分类号： A61F2/44 , A61F2/30742 , A61F2/442 , A61F2/4455 , A61F2002/30079 , A61F2002/3008 , A61F2002/30133 , A61F2002/30365 , A61F2002/30405 , A61F2002/30476 , A61F2002/30484 , A61F2002/30499 , A61F2002/30505 , A61F2002/30514 , A61F2002/30522 , A61F2002/30525 , A61F2002/3055 , A61F2002/30579 , A61F2002/30581 , A61F2002/30589 , A61F2002/30601 , A61F2002/30841 , A61F2002/482 , A61F2002/485 , A61F2210/009 , A61F2220/0025 , A61F2220/0033 , A61F2230/0015 , A61F2250/0007 , A61F2250/0069 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023
摘要： A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can also be corrected, and natural curvatures restored. Preferably, the implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system preferably having a plurality of locking elements to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning
摘要翻译：脊柱植入物，其构造成部署在相邻的椎体之间。植入物具有至少一个具有缩回构型的可延伸的支撑元件，以便于植入物的展开和延伸构造，以便扩大植入物并有效地分散椎间盘空间，稳定运动节段并消除病理脊柱运动。角度变形也可以被修正，自然曲率恢复。优选地，植入物在其未展开状态下具有小于其通常通过以在椎间空间内展开的神经孔的尺寸的最小尺寸。植入物设置有锁定系统，优选地具有多个锁定元件以将植入物锁定在延伸构造中。也可以提供骨接合锚，以确保安全的定位

10. 发明授权

US06767347B2 Catheter for delivery of energy to a surgical site 有权
标题翻译：导管将能量输送到手术部位
公开(公告)号：US06767347B2
公开(公告)日：2004-07-27
申请号：US09776231
申请日：2001-02-01
申请人： Hugh R. Sharkey , Joel Saal , Jeffrey A. Saal , John E. Ashley
发明人： Hugh R. Sharkey , Joel Saal , Jeffrey A. Saal , John E. Ashley
IPC分类号： A61B1818
CPC分类号： A61B18/082 , A61B10/02 , A61B17/00491 , A61B17/1671 , A61B17/29 , A61B17/320016 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B18/00 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/32113 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1412 , A61B2018/1425 , A61B2018/1435 , A61B2018/1455 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0144 , A61M25/0155 , A61M25/0158 , A61M2025/0063 , A61M2025/0064 , A61M2025/0163 , A61N1/06 , A61N1/40
摘要： A catheter for delivering energy to a surgical site is disclosed. The catheter includes at a proximal end a handle and at a distal end a probe. The catheter includes at least one energy delivery device and an activation element. The at least one energy delivery device is located at the distal end of the catheter to deliver energy to portions of the surgical site. The activation element is located at the distal end of the catheter, to transition the probe from a linear to a multi-dimensional shape, within the surgical site. Methods for deploying the probe from the linear to multi-dimensional shape are disclosed. In another embodiment of the invention, the catheter includes a heating element fabricated on a substrate by photo-etching to deliver thermal energy to portions of the surgical site. In another embodiment of the invention, the catheter includes an energy delivery element, a tip and a blade. The energy delivery element is located at the distal end of the catheter to deliver energy to portions of the intervertebral disc. The blade is positioned within a first lumen of the tip and is extensible beyond the tip, to cut selected portions within the intervertebral disc. In another embodiment of the invention, a catheter includes both energy and material transfer elements and an interface on the handle thereof. The interface couples the energy delivery element and the material transfer element to external devices for energy and material transfer to and from the intervertebral disc.

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