专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06492501B1 Water soluble acrylic membrane-polymer protein amphiphilic complex and application to diagnosis methods 有权
标题翻译：水溶性丙烯酸聚合物蛋白质两亲性复合物及应用于诊断方法
公开(公告)号：US06492501B1
公开(公告)日：2002-12-10
申请号：US09331036
申请日：1999-11-05
申请人： Jean-Luc Popot , Christophe Tribet , Roland Audebert
发明人： Jean-Luc Popot , Christophe Tribet , Roland Audebert
IPC分类号： C07K1708
CPC分类号： G01N33/6803 , C08F8/32 , C08F8/44 , G01N33/5432 , Y10S530/815 , C08F20/06
摘要： The invention concerns a water soluble vinyl membrane-polymer protein amphiphilic complex, characterised in that said vinyl polymer corresponds to formula (I) in which: R1 is a group: COO⊖ M+ M+ being an alkaline cation, COOR7, R7 being a sugar radical; polyoxyalkylene, polyoxyethylene; N-pyrrolidonyl; phenyl sulphonate; CONR8R9, R8 and R9 identical or different being hydrogen atom, a sugar radical, polyoxyalkylene, in particular polyoxyethylene, a zwitterion radical; R4, R5, R6 identical or different are hydrogen atom, or methyl radical; R2 is a COOR12 or CONR13R14 radical, R12 being a linear or branched alkyl or alkylene radical; R13, R14 identical or different have one of the meanings of R12, and moreover one of the two can correspond to hydrogen atom; R3 is a COOR15 or CONR16R17 radical; R15 being a (C1-C5) alkyl radical; R16, R17 having one if the meanings of R15 and moreover one of the two can correspond to hydrogen atom; x, y, z correspond to the respective percentages of units. The complex is applicable for producing reagent and diagnosis kits.
摘要翻译：本发明涉及一种水溶性乙烯基膜 - 聚合物蛋白质两亲性复合物，其特征在于所述乙烯基聚合物对应于式（I），其中：R 1为基团：COO m M + M +为碱性阳离子，COOR 7，R 7为糖基 ; 聚氧化烯，聚氧乙烯; N-吡咯烷酮; 苯基磺酸盐; CONR8R9，R8和R9相同或不同，为氢原子，糖基，聚氧化烯，特别是聚氧乙烯，两性离子基; R4，R5，R6相同或不同，是氢原子或甲基; R2是COOR12或CONR13R14基团，R12是直链或支链烷基或亚烷基; R13，R14相同或不同，具有R12的含义之一，而且两者之一可以对应于氢原子; R3是COOR15或CONR16R17基团; R15为（C1-C5）烷基; R16，R17如果R15的含义和二者之一可以对应于氢原子; x，y，z对应于单位的相应百分比。该复合物适用于生产试剂和诊断试剂盒。

2. 发明授权

US08642309B2 Polymers comprising a majority of amphiphilic monomers intended for trapping and manipulating membrane proteins 有权
标题翻译：包含大多数旨在捕获和操纵膜蛋白的两亲性单体的聚合物
公开(公告)号：US08642309B2
公开(公告)日：2014-02-04
申请号：US13509853
申请日：2010-11-16
申请人： Bernard Pucci , Fabrice Giusti , Paola Bazzacco , Jean-Luc Popot , Sharma Kshatrapati Shivaji , Gregory Durand
发明人： Bernard Pucci , Fabrice Giusti , Paola Bazzacco , Jean-Luc Popot , Sharma Kshatrapati Shivaji , Gregory Durand
IPC分类号： C08F24/00 , C08L89/00 , C12N11/04
CPC分类号： C08F220/60 , C12N11/08
摘要： The invention relates to an amphiphilic polymer comprising at least 75% of amphiphilic monomers of formula (I), the average molar mass of the polymer being between 800 and 100 000, and also water-soluble complexes between the polymer according to the invention and a hydrophobic or amphiphilic compound, in particular a membrane protein, a concentrated aqueous solution of one or more such complex(es), a product comprising one or more such complex(es) attached to a substrate by means of the polymer according to the invention, and various uses of these products.
摘要翻译：本发明涉及两亲性聚合物，其包含至少75％的式（I）的两亲性单体，聚合物的平均摩尔质量为800至100000，以及根据本发明的聚合物与水溶性络合物之间的水溶性络合物，疏水性或两亲性化合物，特别是膜蛋白，一种或多种这样的络合物的浓缩水溶液，包含一种或多种这样的复合物的产物，其通过根据本发明的聚合物附着到基底上，以及这些产品的各种用途。

3. 发明申请

US20130005016A1 POLYMERS COMPRISING A MAJORITY OF AMPHIPHILIC MONOMERS INTENDED FOR TRAPPING AND MANIPULATIONF MEMBRANE PROTEINS 有权
标题翻译：包含用于捕获和操作膜蛋白的大分子单体的主要聚合物
公开(公告)号：US20130005016A1
公开(公告)日：2013-01-03
申请号：US13509853
申请日：2010-11-16
申请人： Bernard Pucci , Jean-Luc Popot , Sharma Kshatrapati Shivaji , Fabrice Giusti , Paola Bazzacco , Gregory Durand
发明人： Bernard Pucci , Jean-Luc Popot , Sharma Kshatrapati Shivaji , Fabrice Giusti , Paola Bazzacco , Gregory Durand
IPC分类号： C08F24/00 , C12N11/04 , C08L89/00
CPC分类号： C08F220/60 , C12N11/08
摘要： The invention relates to an amphiphilic polymer comprising at least 75% of amphiphilic monomers of formula (I), the average molar mass of the polymer being between 800 and 100 000, and also water-soluble complexes between the polymer according to the invention and a hydrophobic or amphiphilic compound, in particular a membrane protein, a concentrated aqueous solution of one or more such complex(es), a product comprising one or more such complex(es) attached to a substrate by means of the polymer according to the invention, and various uses of these products.
摘要翻译：本发明涉及两亲性聚合物，其包含至少75％的式（I）的两亲性单体，聚合物的平均摩尔质量为800至100000，以及根据本发明的聚合物与水溶性络合物之间的水溶性络合物，疏水性或两亲性化合物，特别是膜蛋白，一种或多种这样的络合物的浓缩水溶液，包含一种或多种这样的复合物的产物，其通过根据本发明的聚合物附着于基底，以及这些产品的各种用途。

4. 发明申请

US20130023026A1 IMMOBILIZATION OF MEMBRANE PROTEINS ONTO SUPPORTS VIA AN AMPHIPHILE 有权
标题翻译：通过AMPHIPHILE将膜蛋白质固定在支持物上
公开(公告)号：US20130023026A1
公开(公告)日：2013-01-24
申请号：US13479890
申请日：2012-05-24
申请人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
发明人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
IPC分类号： C08F20/56 , C12N11/08
CPC分类号： C07K1/1077 , C07K17/06
摘要： The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
摘要翻译：本发明涉及膜蛋白固定在载体上的领域。本发明涉及包含载体和附着于其表面的至少一种膜蛋白的产品，其特征在于所述膜蛋白使用所述膜蛋白与之复合的两亲分子连接到所述载体上。它还涉及一种制备此类产品的方法，以及诊断，药物设计和生物技术领域的各种应用。它还涉及一种试剂盒以及官能化两亲性分子，用于制备根据本发明的包含载体和两亲分子的产物，其中两亲分子和载体通过疏水键，离子键，特定键相互作用或共价键。

5. 发明申请

US20090275066A1 IMMOBILIZATION OF MEMBRANE PORTEINS ONTO SUPPORTS VIA AN AMPHIPHILE 有权
标题翻译：通过AMPHIPHILE将膜蛋白质固定在支持物上
公开(公告)号：US20090275066A1
公开(公告)日：2009-11-05
申请号：US12514656
申请日：2007-11-13
申请人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
发明人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
IPC分类号： C12Q1/34 , C07K17/00 , C07K14/76 , C07K14/555 , C07K16/00 , C12N11/00 , G01N33/543 , C40B30/00 , C12N9/00 , C08F210/00 , C07K2/00 , C08B37/00 , C08F251/00
CPC分类号： C07K1/1077 , C07K17/06
摘要： The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
摘要翻译：本发明涉及膜蛋白固定在载体上的领域。本发明涉及包含载体和附着于其表面的至少一种膜蛋白的产品，其特征在于所述膜蛋白使用所述膜蛋白与之复合的两亲分子连接到所述载体上。它还涉及一种制备此类产品的方法，以及诊断，药物设计和生物技术领域的各种应用。它还涉及一种试剂盒以及官能化两亲性分子，用于制备根据本发明的包含载体和两亲分子的产物，其中两亲分子和载体通过疏水键，离子键，特定键相互作用或共价键。

6. 发明授权

US08674044B2 Immobilization of membrane proteins onto supports via an amphiphile 有权
标题翻译：通过两亲物将膜蛋白固定在载体上
公开(公告)号：US08674044B2
公开(公告)日：2014-03-18
申请号：US13479890
申请日：2012-05-24
申请人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
发明人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
IPC分类号： A61K47/48 , C08G63/48 , C08G63/91 , C08L89/00 , D21H19/50 , C08F20/00 , C08F22/38 , C08F26/00 , C08F120/00 , C08F220/54 , C08F220/70 , C08F222/38 , C08F226/02 , C08F236/00 , C12Q1/00
CPC分类号： C07K1/1077 , C07K17/06
摘要： The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
摘要翻译：本发明涉及膜蛋白固定在载体上的领域。本发明涉及包含载体和附着于其表面的至少一种膜蛋白的产品，其特征在于所述膜蛋白使用所述膜蛋白与之复合的两亲分子连接到所述载体上。它还涉及一种制备此类产品的方法，以及诊断，药物设计和生物技术领域的各种应用。它还涉及一种试剂盒以及官能化两亲性分子，用于制备根据本发明的包含载体和两亲分子的产物，其中两亲分子和载体通过疏水键，离子键，特定键相互作用或共价键。

7. 发明授权

US08207263B2 Immobilization of membrane proteins onto supports via an amphiphile 有权
标题翻译：通过两亲物将膜蛋白固定在载体上
公开(公告)号：US08207263B2
公开(公告)日：2012-06-26
申请号：US12514656
申请日：2007-11-13
申请人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
发明人： Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
IPC分类号： A61K47/48 , C08G63/48 , C08G63/91 , C08L89/00 , D21H19/50 , C08F20/00 , C08F22/38 , C08F26/00 , C08F120/00 , C08F220/54 , C08F220/70 , C08F222/38 , C08F226/02 , C08F236/00 , C12Q1/00
CPC分类号： C07K1/1077 , C07K17/06
摘要： The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
摘要翻译：本发明涉及膜蛋白固定在载体上的领域。本发明涉及包含载体和附着于其表面的至少一种膜蛋白的产品，其特征在于所述膜蛋白使用所述膜蛋白与之复合的两亲分子连接到所述载体上。它还涉及一种制备此类产品的方法，以及诊断，药物设计和生物技术领域的各种应用。它还涉及一种试剂盒以及官能化两亲性分子，用于制备根据本发明的包含载体和两亲分子的产物，其中两亲分子和载体通过疏水键，离子键，特定键相互作用或共价键。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式