专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110154648A1 ELECTRONIC SENSING OF BIOLOGICAL AND CHEMICAL AGENTS USING FUNCTIONALIZED NANOSTRUCTURES 审中-公开
标题翻译：使用功能化纳米结构的生物和化学试剂的电子感测
公开(公告)号：US20110154648A1
公开(公告)日：2011-06-30
申请号：US13047593
申请日：2011-03-14
申请人： Jean Christophe Gabriel , George Gruner , Philip Collins , Basil Swanson , Fred Wudl
发明人： Jean Christophe Gabriel , George Gruner , Philip Collins , Basil Swanson , Fred Wudl
IPC分类号： H05K13/00 , B82Y99/00
CPC分类号： B82Y30/00 , G01N33/5438 , G01N33/551 , G01N33/566 , G01N33/582 , Y10T29/49002
摘要： This invention provides for an apparatus and a method for detecting the presence of pathogenic agents with sensors containing functionalized nanostructures integrated into circuits on silicon chips. The nanostructures are functionalized with molecular transducers that recognize and bind targeted analytes which are diagnostic of the pathogenic agent of interest. The molecular transducer includes a receptor portion, which binds the analyte, and an anchor portion that attaches to the nanostructure. Upon binding of the analyte, a change in molecular configuration represented by the newly formed receptor-analyte complex creates a force that is transmitted to the nanostructure via the anchor portion of the transducer. The effect of the force transmitted to the nanostructure is to alter its conductivity. The change in conductivity of the nanotube thus represents a signal that indicates the presence of the pathogenic agent of interest.
摘要翻译：本发明提供了一种用于检测病原体的存在的装置和方法，所述传感器包含集成在硅芯片上的电路中的功能化纳米结构。纳米结构用识别和结合目标分析物的分子换能器进行功能化，这些目标分析物是目标病原体的诊断。分子换能器包括结合分析物的受体部分和附着到纳米结构的锚定部分。在分析物结合后，由新形成的受体 - 分析物复合物表示的分子构型的变化产生通过换能器的锚定部分传递到纳米结构的力。传递到纳米结构的力的作用是改变其导电性。因此，纳米管的电导率的变化表示表示感兴趣的病原体的存在的信号。

2. 发明申请

US20100231242A1 ELECTRONIC SENSING OF BIOLOGICAL AND CHEMICAL AGENTS USING FUNCTIONALIZED NANOSTRUCTURES 审中-公开
标题翻译：使用功能化纳米结构的生物和化学试剂的电子感测
公开(公告)号：US20100231242A1
公开(公告)日：2010-09-16
申请号：US12634525
申请日：2009-12-09
申请人： Jean Christophe Gabriel , George Gruner , Philip Collins , Basil Swanson , Fred Wudl
发明人： Jean Christophe Gabriel , George Gruner , Philip Collins , Basil Swanson , Fred Wudl
IPC分类号： G01R27/08
CPC分类号： B82Y30/00 , G01N33/5438 , G01N33/551 , G01N33/566 , G01N33/582 , Y10T29/49002
摘要： This invention provides for an apparatus and a method for detecting the presence of pathogenic agents with sensors containing functionalized nanostructures integrated into circuits on silicon chips. The nanostructures are functionalized with molecular transducers that recognize and bind targeted analytes which are diagnostic of the pathogenic agent of interest. The molecular transducer includes a receptor portion, which binds the analyte, and an anchor portion that attaches to the nanostructure. Upon binding of the analyte, a change in molecular configuration represented by the newly formed receptor-analyte complex creates a force that is transmitted to the nanostructure via the anchor portion of the transducer. The effect of the force transmitted to the nanostructure is to alter its conductivity. The change in conductivity of the nanotube thus represents a signal that indicates the presence of the pathogenic agent of interest.
摘要翻译：本发明提供了一种用于检测病原体的存在的装置和方法，所述传感器包含集成在硅芯片上的电路中的功能化纳米结构。纳米结构用识别和结合目标分析物的分子换能器进行功能化，这些目标分析物是目标病原体的诊断。分子换能器包括结合分析物的受体部分和附着到纳米结构的锚定部分。在分析物结合后，由新形成的受体 - 分析物复合物表示的分子构型的变化产生通过换能器的锚定部分传递到纳米结构的力。传递到纳米结构的力的作用是改变其导电性。因此，纳米管的电导率的变化表示表示感兴趣的病原体的存在的信号。

3. 发明申请

US20070178477A1 Nanotube sensor devices for DNA detection 审中-公开
标题翻译：用于DNA检测的纳米管传感器装置
公开(公告)号：US20070178477A1
公开(公告)日：2007-08-02
申请号：US11212026
申请日：2005-08-24
申请人： Charles Joiner , Jean-Christophe Gabriel , George Gruner , Alexander Star
发明人： Charles Joiner , Jean-Christophe Gabriel , George Gruner , Alexander Star
IPC分类号： C12Q1/68 , C12M3/00
CPC分类号： C12Q1/6825 , G01N27/4145 , G01N27/4146 , C12Q2565/631 , C12Q2565/107
摘要： A nanotube device is configured as an electronic sensor for a target DNA sequence. A film of nanotubes is deposited over electrodes on a substrate. A solution of single-strand DNA is prepared so as to be complementary to a target DNA sequence. The DNA solution is deposited over the electrodes, dried, and removed from the substrate except in a region between the electrodes. The resulting structure includes strands of the desired DNA sequence in direct contact with nanotubes between opposing electrodes, to form a sensor that is electrically responsive to the presence of target DNA strands. Alternative assay embodiments are described which employ linker groups to attach ssDNA probes to the nanotube sensor device.
摘要翻译：纳米管装置配置为目标DNA序列的电子传感器。将纳米管膜沉积在基板上的电极上。制备单链DNA的溶液以与靶DNA序列互补。将DNA溶液沉积在电极上，干燥，除去电极之外的区域。所得结构包括与相对电极之间的纳米管直接接触的所需DNA序列的链，以形成对目标DNA链的存在电响应的传感器。描述了使用连接体将ssDNA探针连接到纳米管传感器装置的替代试验实施方案。

4. 发明申请

US20060263255A1 Nanoelectronic sensor system and hydrogen-sensitive functionalization 审中-公开
标题翻译：纳米电子传感器系统和氢敏感功能化
公开(公告)号：US20060263255A1
公开(公告)日：2006-11-23
申请号：US11354561
申请日：2006-02-14
申请人： Tzong-Ru Han , Alexander Star , Jean-Christophe Gabriel , Sergei Skarupo , John Passmore , Philip Collins , Keith Bradley , Darin Olson
发明人： Tzong-Ru Han , Alexander Star , Jean-Christophe Gabriel , Sergei Skarupo , John Passmore , Philip Collins , Keith Bradley , Darin Olson
IPC分类号： G01N33/00
CPC分类号： B82Y15/00 , B82Y10/00 , B82Y30/00 , G01N27/4141 , G01N27/4146 , G01N33/005
摘要： A new sensing technology for chemical/biomolecular sensors is provided. One such sensor detects molecular hydrogen (H2) using nanoelectronic components. A tiny, low-cost nanosensor chip can offer: (i) performance that matches or exceeds that of existing technology, (ii) plug-and-play simplicity with both digital and analog control systems, and (ii) the small size and low power consumption needed for wireless integration.
摘要翻译：提供了一种用于化学/生物分子传感器的新型传感技术。一种这样的传感器使用纳米电子部件检测分子氢（H 2 N 2）。一个小型，低成本的纳米传感器芯片可以提供：（i）匹配或超过现有技术的性能，（ii）数字和模拟控制系统的即插即用简单性，以及（ii）小尺寸和低无线集成所需的功耗。

5. 发明申请

US20060165577A1 Boron oxide and related compounds for hydrogen storage 失效
公开(公告)号：US20060165577A1
公开(公告)日：2006-07-27
申请号：US11271446
申请日：2005-11-09
申请人： Seung-Hoon Jhi , Young-Kyun Kwon , Keith Bradley , Jean-Christophe Gabriel
发明人： Seung-Hoon Jhi , Young-Kyun Kwon , Keith Bradley , Jean-Christophe Gabriel
IPC分类号： C01B17/66 , C01B35/10
CPC分类号： B01D53/02 , B01D2253/104 , B01D2253/106 , B01D2253/112 , B01D2253/306 , B01D2253/308 , B01D2256/16 , B01D2259/4525 , C01B3/001 , Y02E60/324
摘要： A hydrogen storage medium is provided, where the medium is comprised of boron oxide and closely related compounds such as orthoboric acid, metaboric acid, hydrated boric acid, and disodium borohydrate. The medium is substantially an amorphous glassy network, albeit with local regions of order, pores, and networks that provide surface area. Hydrogen is adsorbed by the medium with a heat of adsorption of about 9 kJ/mol to about 13 kJ/mol, a value which is higher than that of the heat of adsorption of hydrogen on carbon. The value for the heat of adsorption of hydrogen on the inventive storage medium is provided by computation, and corroborated by experimental observation. The higher heat of adsorption of the medium provides for operation at temperatures higher temperatures higher than those provided by carbon. Further provided are methods by which the storage medium can be prepared in such a form so as to permit high capacity hydrogen storage, as well as an apparatus, with the inventive medium disposed therein, for storing hydrogen.

6. 发明申请

US20050157445A1 Nanostructures with electrodeposited nanoparticles 有权
标题翻译：具有电沉积纳米粒子的纳米结构
公开(公告)号：US20050157445A1
公开(公告)日：2005-07-21
申请号：US10945803
申请日：2004-09-20
申请人： Keith Bradley , Alona Davis , Jean-Christophe Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
发明人： Keith Bradley , Alona Davis , Jean-Christophe Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
IPC分类号： G01N27/00 , G01N27/414 , G01N33/00 , H02H1/00
CPC分类号： B82Y30/00 , G01N27/4146 , G01N33/005 , Y10S977/72
摘要： A nanoelectronic device includes a nanostructure, such as a nanotube or network of nanotubes, disposed on a substrate. Nanoparticles are disposed on or adjacent to the nanostructure so as to operatively effect the electrical properties of the nanostructure. The nanoparticles may be composed of metals, metal oxides, or salts, and nanoparticles composed of different materials may be present. The amount of nanoparticles may be controlled to preserve semiconductive properties of the nanostructure, and the substrate immediately adjacent to the nanostructure may remain substantially free of nanoparticles. A method for fabricating the device includes electrodeposition of the nanoparticles using one or more solutions of dissolved ions while providing an electric current to the nanostructures but not to the surrounding substrate.
摘要翻译：纳米电子器件包括设置在衬底上的纳米结构，例如纳米管或纳米管网络。将纳米颗粒设置在纳米结构上或与纳米结构相邻，以便有效地影响纳米结构的电性能。纳米颗粒可以由金属，金属氧化物或盐组成，并且可以存在由不同材料组成的纳米颗粒。可以控制纳米颗粒的量以保持纳米结构的半导体性质，并且紧邻纳米结构的衬底可以基本上不含纳米颗粒。制造该器件的方法包括使用一种或多种溶解离子的溶液电沉积纳米颗粒，同时向纳米结构提供电流，而不向周围的衬底提供电流。

7. 发明授权

US06834508B2 Hydrogen storage and supply system 失效
标题翻译：储氢系统
公开(公告)号：US06834508B2
公开(公告)日：2004-12-28
申请号：US10285731
申请日：2002-10-31
申请人： Keith Bradley , Jeff Wyatt , Seung-Hoon Jhi , Young-Kyun Kwon , Jean Christophe Gabriel , George Gruner
发明人： Keith Bradley , Jeff Wyatt , Seung-Hoon Jhi , Young-Kyun Kwon , Jean Christophe Gabriel , George Gruner
IPC分类号： F17C1100
CPC分类号： F17C11/005 , G06Q50/06 , Y02E60/321 , Y02P90/45
摘要： This invention provides for an apparatus and a method for operation of a cryogenic hydrogen storage system that contains a porous medium configured to adsorb hydrogen. The hydrogen storage and supply system includes a hydrogen source apparatus and a cryosorptive storage apparatus. Methods and devices that allow for an energy efficient filling of the cryosorptive apparatus from the hydrogen source apparatus are described. The cryosorptive hydrogen storage apparatus is filled with cold, pressurized hydrogen. During the course of filling, heat is generated in the cryosorptive storage device by the process of hydrogen adsorption on to the host medium. Methods and devices are provided for the removal the generated heat and the warm hydrogen. Further provided are devices and methods for the capture and recycle of escaped hydrogen within the hydrogen source apparatus.
摘要翻译：本发明提供了一种用于操作低温氢存储系统的装置和方法，所述低温储氢系统包含构造成吸附氢气的多孔介质。氢存储和供给系统包括氢源装置和低温存储装置。描述允许从氢源装置对冷冻摄影装置进行能量效率充填的方法和装置。冷藏式氢存储装置充满冷的加压氢气。在填充过程中，通过氢吸附到主介质上的过程，在冷冻存储装置中产生热量。提供了用于去除所产生的热量和温氢的方法和装置。还提供了用于在氢源装置内捕获和再循环逸出的氢的装置和方法。

8. 发明申请

US20070140946A1 Dispersed growth of nanotubes on a substrate 审中-公开
标题翻译：纳米管在基体上的分散生长
公开(公告)号：US20070140946A1
公开(公告)日：2007-06-21
申请号：US11703293
申请日：2007-02-07
申请人： Jean-Christophe Gabriel , Keith Bradley , Philip Collins
发明人： Jean-Christophe Gabriel , Keith Bradley , Philip Collins
IPC分类号： D01F9/12
CPC分类号： D01F9/12 , B82Y10/00 , B82Y30/00 , D01F9/127 , H01L29/1025 , H01L29/12 , H01L29/66409 , H01L29/772
摘要： Methods of forming a dispersion of nanostructures, a distribution of carbon nanotubes, and an array of nanostructure devices are described. The methods involve providing a substrate, applying growth promoter to at least a portion of the substrate, exposing the substrate and the growth promoter to a plasma, and forming a dispersion of nanostructures from the growth promoter after the plasma exposure. Exposing the substrate and the growth promoter to a plasma disperses at least a portion of the growth promoter as distinct, isolated growth promoter areas over the substrate. Preferably, the growth promoter areas are nanoparticles between about 1 nm and 50 nm in size and they are dispersed approximately uniformly over the substrate. An array of nanostructure devices is also described. The array of devices includes a substrate, a dispersion of nanostructures disposed discontinuously on the substrate and an array of electrodes in contact with the dispersion of nanostructures. The nanostructures may be nanotubes or nanowires. Preferably, the dispersion of nanostructures is approximately planar and substantially in contact with the substrate. Regions containing nanostructures can provide electrical communication between two or more electrodes.
摘要翻译：描述形成纳米结构分散体，碳纳米管分布和纳米结构器件阵列的方法。所述方法包括提供底物，将生长促进剂施用于至少一部分底物，将底物和生长促进剂暴露于血浆，以及在等离子体暴露后从生长促进剂形成纳米结构的分散体。将底物和生长促进剂暴露于等离子体将至少一部分生长促进剂分散在衬底上作为不同的分离的生长促进剂区域。优选地，生长促进剂区域是尺寸在约1nm和50nm之间的纳米颗粒，并且它们大致均匀地分散在基底上。还描述了纳米结构器件的阵列。器件阵列包括衬底，不连续地设置在衬底上的纳米结构的分散体和与纳米结构分散体接触的电极阵列。纳米结构可以是纳米管或纳米线。优选地，纳米结构的分散体近似平面并且基本上与基底接触。包含纳米结构的区域可以提供两个或更多个电极之间的电连通。

9. 发明申请

US20070132043A1 Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices 有权
标题翻译：用于化学和生物分析物的纳米电子传感器，包括电容和生物膜装置
公开(公告)号：US20070132043A1
公开(公告)日：2007-06-14
申请号：US11400038
申请日：2006-04-06
申请人： Keith Bradley , Ying-Lan Chang , Jean-Christophe Gabriel , John Passmore , Sergei Skarupo , Eugene Tu , Christian Valcke
发明人： Keith Bradley , Ying-Lan Chang , Jean-Christophe Gabriel , John Passmore , Sergei Skarupo , Eugene Tu , Christian Valcke
IPC分类号： H01L29/00
CPC分类号： G01N27/4146 , B82Y10/00 , B82Y15/00 , G01N27/4145 , H01L29/0665 , H01L29/0673 , Y10S977/742
摘要： Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes inorganic gases, organic vapors, biomolecules, viruses and the like. A number of embodiments of capacitive sensors having alternative architectures are described. Particular examples include integrated cell membranes and membrane-like structures in nanoelectronic sensors.
摘要翻译：描述了纳米电子传感器的实施例，包括用于检测分析物无机气体，有机蒸气，生物分子，病毒等的传感器。描述了具有替代架构的电容传感器的许多实施例。具体实例包括纳米电子传感器中的集成细胞膜和膜状结构。

10. 发明申请

US20070208243A1 Nanoelectronic glucose sensors 审中-公开
标题翻译：纳米电子葡萄糖传感器
公开(公告)号：US20070208243A1
公开(公告)日：2007-09-06
申请号：US11274747
申请日：2005-11-15
申请人： Jean-Christophe Gabriel , Shripal Gandhi , Alexander Star , Christian Valcke
发明人： Jean-Christophe Gabriel , Shripal Gandhi , Alexander Star , Christian Valcke
IPC分类号： A61B5/05
CPC分类号： B82Y15/00 , A61B5/14532 , A61B5/14865 , A61B2562/04 , B82Y10/00 , C12Q1/006 , G01N27/4146 , H01L51/0049
摘要： A nanostructured electronic device for detection and measurement of biomolecules, such as blood glucose. Also disclosed are methods of using and manufacturing devices employing nanotubes as electronic transducers.
摘要翻译：用于检测和测量生物分子的纳米结构电子装置，例如血糖。还公开了使用和制造使用纳米管作为电子换能器的装置的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式