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    • 7. 发明申请
    • SYSTEM AND METHOD FOR MONITORING AN ANALYTE
    • 用于监测分析仪的系统和方法
    • US20070111225A1
    • 2007-05-17
    • US11463834
    • 2006-08-10
    • James LambertAnita FisherMark Borchert
    • James LambertAnita FisherMark Borchert
    • C12Q1/68G01N33/53G06F19/00
    • G01N21/6428G01N15/1459G01N2015/0088
    • The present invention provides for a monitoring system and method to monitor an analyte, including determining the presence of the analyte and analyzing the analyte; for example, cellular chorography and biological threats. The system and method use a fluidics apparatus (e.g., a flow cytometer), a computer, a probe synthesizer and/or an initial set of fluorophore conjugated probes to monitor the analyte. The fluidics apparatus is adapted to determine the presence of the analyte based on the intrinsic fluorescence of the analyte, and/or to determine the binding of the probes to the analyte in the sample. The binding information is analyzed by the computer by comparing the binding results with a database of information regarding the analyte. The information gained allows the probe synthesizer to synthesize new probes for a subsequent iteration of the process, wherein additional information regarding the analyte is gained with every iteration.
    • 本发明提供了一种用于监测分析物的监测系统和方法,包括确定分析物的存在并分析分析物; 例如,细胞chorography和生物威胁。 该系统和方法使用流体学装置(例如,流式细胞仪),计算机,探针合成仪和/或初始的荧光团缀合探针组来监测分析物。 流体设备适于基于分析物的固有荧光确定分析物的存在,和/或确定探针与样品中分析物的结合。 通过将结合结果与关于分析物的信息的数据库进行比较,计算机分析结合信息。 所获得的信息允许探针合成器合成新的探针,用于随后的迭代过程,其中每次迭代获得关于分析物的附加信息。